Granulocytic Sarcoma

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Xiaoming Zhang - One of the best experts on this subject based on the ideXlab platform.

  • 18f fdg pet ct of primary cervical Granulocytic Sarcoma
    Clinical Nuclear Medicine, 2015
    Co-Authors: Lichun Zheng, Xiangliu Ouyang, Wenjun Zhang, Xiaoming Zhang
    Abstract:

    : Granulocytic Sarcoma is an uncommon solid extramedullary tumor composed of immature leukocytes and commonly associated with acute myelogenous leukemia. Isolated Granulocytic Sarcoma in the cervix of uterus is exceedingly rare. Hereby we describe a case of FDG PET/CT finding of cervical Granulocytic Sarcoma without acute myelogenous leukemia in a 51-year-old patient.

  • 18F-FDG PET/CT of Primary Cervical Granulocytic Sarcoma.
    Clinical Nuclear Medicine, 2015
    Co-Authors: Lichun Zheng, Xiangliu Ouyang, Wenjun Zhang, Xiaoming Zhang
    Abstract:

    : Granulocytic Sarcoma is an uncommon solid extramedullary tumor composed of immature leukocytes and commonly associated with acute myelogenous leukemia. Isolated Granulocytic Sarcoma in the cervix of uterus is exceedingly rare. Hereby we describe a case of FDG PET/CT finding of cervical Granulocytic Sarcoma without acute myelogenous leukemia in a 51-year-old patient.

Patricia Aoun - One of the best experts on this subject based on the ideXlab platform.

  • Granulocytic Sarcoma of the small intestine
    Archives of Pathology & Laboratory Medicine, 2009
    Co-Authors: Shane K Kohl, Patricia Aoun
    Abstract:

    Abstract Granulocytic Sarcoma is an extramedullary tumor of myeloblasts and/or immature myeloid cells, which can develop at any anatomic site and is often a forerunner to the development of acute myelogenous leukemia. Granulocytic Sarcoma of the gastrointestinal tract most frequently involves the small intestine and most often presents with abdominal pain and obstruction. Pathologists must consider Granulocytic Sarcoma in any mass of unknown origin with a diffusely infiltrating population of tumor cells, as the diagnosis is often initially unrecognized, especially in nonleukemic patients. Multiple ancillary modalities are available to assist pathologists in making the correct diagnosis so that appropriate therapy can be initiated.

Lichun Zheng - One of the best experts on this subject based on the ideXlab platform.

  • 18f fdg pet ct of primary cervical Granulocytic Sarcoma
    Clinical Nuclear Medicine, 2015
    Co-Authors: Lichun Zheng, Xiangliu Ouyang, Wenjun Zhang, Xiaoming Zhang
    Abstract:

    : Granulocytic Sarcoma is an uncommon solid extramedullary tumor composed of immature leukocytes and commonly associated with acute myelogenous leukemia. Isolated Granulocytic Sarcoma in the cervix of uterus is exceedingly rare. Hereby we describe a case of FDG PET/CT finding of cervical Granulocytic Sarcoma without acute myelogenous leukemia in a 51-year-old patient.

  • 18F-FDG PET/CT of Primary Cervical Granulocytic Sarcoma.
    Clinical Nuclear Medicine, 2015
    Co-Authors: Lichun Zheng, Xiangliu Ouyang, Wenjun Zhang, Xiaoming Zhang
    Abstract:

    : Granulocytic Sarcoma is an uncommon solid extramedullary tumor composed of immature leukocytes and commonly associated with acute myelogenous leukemia. Isolated Granulocytic Sarcoma in the cervix of uterus is exceedingly rare. Hereby we describe a case of FDG PET/CT finding of cervical Granulocytic Sarcoma without acute myelogenous leukemia in a 51-year-old patient.

Miguel N Burnier - One of the best experts on this subject based on the ideXlab platform.

  • orbital Granulocytic Sarcoma
    British Journal of Ophthalmology, 1997
    Co-Authors: F A Stockl, A M Dolmetsch, M A Saornil, R L Font, Miguel N Burnier
    Abstract:

    AIM Orbital Granulocytic Sarcoma is a localised tumour composed of cells of myeloid origin. Histological diagnosis can be difficult in patients with poorly differentiated orbital tumours and no evidence of systemic leukaemia. The naphthol AS-D chloracetate esterase (Leder stain) and immunohistochemical stains for lysozyme and MAC387 were used to determine the staining characteristics of these tumours. A case series of seven patients with orbital Granulocytic Sarcoma is presented. METHODS Seven patients with orbital Granulocytic Sarcoma were studied. Haematoxylin and eosin, Leder, and lysozyme stained sections were available in seven cases. Unstained formalin fixed paraffin embedded sections of seven cases were available for immunohistochemical evaluation using the avidin-biotin-complex technique for MAC387. RESULTS The mean age of presentation of the orbital tumour was 8.8 years. Four patients presented with an orbital tumour before any systemic manifestations of leukaemia. In two cases the diagnosis of the orbital tumour and systemic leukaemia was made simultaneously. There was one case of established systemic myeloid leukaemia in remission with the subsequent development of orbital Granulocytic Sarcoma. Six of seven cases (86%) were positive for the Leder stain. Five of seven cases (71%) showed positive immunoreactivity with lysozyme. The immunohistochemical stain for MAC387 was positive in all seven cases (100%) including one case that was negative for both lysozyme and Leder stains. CONCLUSIONS Orbital Granulocytic Sarcoma is a tumour that affects children and can present with rapidly progressive proptosis. This tumour may develop before, during, or after the occurrence of systemic leukaemia. The combination of Leder and lysozyme stains is useful in the diagnosis of orbital Granulocytic Sarcoma. MAC387 may be a more reliable marker for orbital Granulocytic Sarcoma.

Seung Eun Jung - One of the best experts on this subject based on the ideXlab platform.

  • Granulocytic Sarcoma of bowel ct findings
    Radiology, 2007
    Co-Authors: Eugene K Choi, Hyun Kwon Ha, Seong Ho Park, Seung Eun Jung
    Abstract:

    Purpose: To evaluate retrospectively the computed tomographic (CT) findings of Granulocytic Sarcoma of the bowel. Materials and Methods: The institutional review boards of all participating institutions approved this study and waived the requirement for informed consent. CT scans were retrospectively reviewed in eight patients (seven men, one woman; age range, 23–71 years; mean age, 46 years) with pathologically proved Granulocytic Sarcoma of the small and/or large bowel. CT findings were evaluated with regard to the sites, morphologic characteristics, and contrast material enhancement patterns of the lesions, along with other ancillary findings (ie, peritoneal and mesenteric infiltration, ascites, lymphadenopathy, bowel perforation, and obstruction). Results: Eight patients had a total of 13 lesions in the bowel (of which eight were pathologically proved), involving the duodenum (n = 1), jejunum (n = 2), ileum (n = 5), sigmoid colon (n = 1), and rectum (n = 4); multifocal bowel lesions were noted in four...

  • MR findings in ovarian Granulocytic Sarcoma.
    British Journal of Radiology, 1999
    Co-Authors: Seung Eun Jung, Kyung Ah Chun, S H Park
    Abstract:

    Granulocytic Sarcoma (chloroma) is a mass of malignant myeloid precursor cells in an extramedullary location. The female genital tract, including the ovary, may be the first site for clinical manifestation of Granulocytic Sarcoma. The MR findings are reported in a case of ovarian Granulocytic Sarcoma which preceded acute myelogenous leukaemia. Granulocytic Sarcoma shows a mixed cystic and solid adnexal mass with intermediate signal intensity on T1 weighted images and hypointensity on T2 weighted images.