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Alexander I. Gray - One of the best experts on this subject based on the ideXlab platform.
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anti inflammatory activity of polygonum bistorta Guaiacum Officinale and hamamelis virginiana in rats
Journal of Pharmacy and Pharmacology, 1994Co-Authors: M. Duwiejua, I. J. Zeitlin, Peter G. Waterman, Alexander I. GrayAbstract:The aqueous ethanolic extracts of Polygonum bistorta L. Polygonaceae, Guaiacum Officinale L. Zygophyllaceae and Hamamelis virginiana L. Hamamelidaceae were screened for anti-inflammatory activity. Administered (100 and 200 mg kg-1, p.o.) before the induction of carrageenan rat paw oedema, extracts of P. bistorta significantly suppressed both the maximal oedema response and the total oedema response (monitored as area under the time course curve). H. virginiana was inactive and G. Officinale was only active at 200 mg kg-1. At 200 mg kg-1 administered before the induction of adjuvant arthritis, P. bistorta significantly inhibited both the acute and chronic phases of the adjuvant-induced rat paw swelling, while G. Officinale and H. virginiana were only active against the chronic phase. Further studies on P. bistorta (100-800 mg kg-1) revealed a dose-dependent inhibition of the carrageenan-induced rat paw oedema over the dose range 100-400 mg kg-1, the E50 value being approximately 158.5 mg kg-1. The extract (200 mg kg-1), administered after the onset of the inflammatory responses reversed the course of both the carrageenan- and adjuvant-induced rat paw swelling. The results confirm that the extracts of P. bistorta, G. Officinale and H. virginiana contain anti-inflammatory substances.
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Anti‐inflammatory Activity of Polygonum bistorta, Guaiacum Officinale and Hamamelis virginiana in Rats
The Journal of pharmacy and pharmacology, 1994Co-Authors: M. Duwiejua, I. J. Zeitlin, Peter G. Waterman, Alexander I. GrayAbstract:Abstract— The aqueous ethanolic extracts of Polygonum bistorta L. Polygonaceae, Guaiacum Officinale L. Zygophyllaceae and Hamamelis virginiana L. Hamamelidaceae were screened for anti-inflammatory activity. Administered (100 and 200 mg kg−1, p.o.) before the induction of carrageenan rat paw oedema, extracts of P. bistorta significantly suppressed both the maximal oedema response and the total oedema response (monitored as area under the time course curve). H. virginiana was inactive and G. Officinale was only active at 200 mg kg−1. At 200 mg kg−1 administered before the induction of adjuvant arthritis, P. bistorta significantly inhibited both the acute and chronic phases of the adjuvant-induced rat paw swelling, while G. Officinale and H. virginiana were only active against the chronic phase. Further studies on P. bistorta (100–800 mg kg−1) revealed a dose-dependent inhibition of the carrageenan-induced rat paw oedema over the dose range 100–400 mg kg−1, the E50 value being approximately 158·5 mg kg−1. The extract (200 mg kg−1), administered after the onset of the inflammatory responses reversed the course of both the carrageenan- and adjuvant- induced rat paw swelling. The results confirm that the extracts of P. bistorta, G. Officinale and H. virginiana contain anti-inflammatory substances.
M. Duwiejua - One of the best experts on this subject based on the ideXlab platform.
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anti inflammatory activity of polygonum bistorta Guaiacum Officinale and hamamelis virginiana in rats
Journal of Pharmacy and Pharmacology, 1994Co-Authors: M. Duwiejua, I. J. Zeitlin, Peter G. Waterman, Alexander I. GrayAbstract:The aqueous ethanolic extracts of Polygonum bistorta L. Polygonaceae, Guaiacum Officinale L. Zygophyllaceae and Hamamelis virginiana L. Hamamelidaceae were screened for anti-inflammatory activity. Administered (100 and 200 mg kg-1, p.o.) before the induction of carrageenan rat paw oedema, extracts of P. bistorta significantly suppressed both the maximal oedema response and the total oedema response (monitored as area under the time course curve). H. virginiana was inactive and G. Officinale was only active at 200 mg kg-1. At 200 mg kg-1 administered before the induction of adjuvant arthritis, P. bistorta significantly inhibited both the acute and chronic phases of the adjuvant-induced rat paw swelling, while G. Officinale and H. virginiana were only active against the chronic phase. Further studies on P. bistorta (100-800 mg kg-1) revealed a dose-dependent inhibition of the carrageenan-induced rat paw oedema over the dose range 100-400 mg kg-1, the E50 value being approximately 158.5 mg kg-1. The extract (200 mg kg-1), administered after the onset of the inflammatory responses reversed the course of both the carrageenan- and adjuvant-induced rat paw swelling. The results confirm that the extracts of P. bistorta, G. Officinale and H. virginiana contain anti-inflammatory substances.
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Anti‐inflammatory Activity of Polygonum bistorta, Guaiacum Officinale and Hamamelis virginiana in Rats
The Journal of pharmacy and pharmacology, 1994Co-Authors: M. Duwiejua, I. J. Zeitlin, Peter G. Waterman, Alexander I. GrayAbstract:Abstract— The aqueous ethanolic extracts of Polygonum bistorta L. Polygonaceae, Guaiacum Officinale L. Zygophyllaceae and Hamamelis virginiana L. Hamamelidaceae were screened for anti-inflammatory activity. Administered (100 and 200 mg kg−1, p.o.) before the induction of carrageenan rat paw oedema, extracts of P. bistorta significantly suppressed both the maximal oedema response and the total oedema response (monitored as area under the time course curve). H. virginiana was inactive and G. Officinale was only active at 200 mg kg−1. At 200 mg kg−1 administered before the induction of adjuvant arthritis, P. bistorta significantly inhibited both the acute and chronic phases of the adjuvant-induced rat paw swelling, while G. Officinale and H. virginiana were only active against the chronic phase. Further studies on P. bistorta (100–800 mg kg−1) revealed a dose-dependent inhibition of the carrageenan-induced rat paw oedema over the dose range 100–400 mg kg−1, the E50 value being approximately 158·5 mg kg−1. The extract (200 mg kg−1), administered after the onset of the inflammatory responses reversed the course of both the carrageenan- and adjuvant- induced rat paw swelling. The results confirm that the extracts of P. bistorta, G. Officinale and H. virginiana contain anti-inflammatory substances.
Peter G. Waterman - One of the best experts on this subject based on the ideXlab platform.
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anti inflammatory activity of polygonum bistorta Guaiacum Officinale and hamamelis virginiana in rats
Journal of Pharmacy and Pharmacology, 1994Co-Authors: M. Duwiejua, I. J. Zeitlin, Peter G. Waterman, Alexander I. GrayAbstract:The aqueous ethanolic extracts of Polygonum bistorta L. Polygonaceae, Guaiacum Officinale L. Zygophyllaceae and Hamamelis virginiana L. Hamamelidaceae were screened for anti-inflammatory activity. Administered (100 and 200 mg kg-1, p.o.) before the induction of carrageenan rat paw oedema, extracts of P. bistorta significantly suppressed both the maximal oedema response and the total oedema response (monitored as area under the time course curve). H. virginiana was inactive and G. Officinale was only active at 200 mg kg-1. At 200 mg kg-1 administered before the induction of adjuvant arthritis, P. bistorta significantly inhibited both the acute and chronic phases of the adjuvant-induced rat paw swelling, while G. Officinale and H. virginiana were only active against the chronic phase. Further studies on P. bistorta (100-800 mg kg-1) revealed a dose-dependent inhibition of the carrageenan-induced rat paw oedema over the dose range 100-400 mg kg-1, the E50 value being approximately 158.5 mg kg-1. The extract (200 mg kg-1), administered after the onset of the inflammatory responses reversed the course of both the carrageenan- and adjuvant-induced rat paw swelling. The results confirm that the extracts of P. bistorta, G. Officinale and H. virginiana contain anti-inflammatory substances.
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Anti‐inflammatory Activity of Polygonum bistorta, Guaiacum Officinale and Hamamelis virginiana in Rats
The Journal of pharmacy and pharmacology, 1994Co-Authors: M. Duwiejua, I. J. Zeitlin, Peter G. Waterman, Alexander I. GrayAbstract:Abstract— The aqueous ethanolic extracts of Polygonum bistorta L. Polygonaceae, Guaiacum Officinale L. Zygophyllaceae and Hamamelis virginiana L. Hamamelidaceae were screened for anti-inflammatory activity. Administered (100 and 200 mg kg−1, p.o.) before the induction of carrageenan rat paw oedema, extracts of P. bistorta significantly suppressed both the maximal oedema response and the total oedema response (monitored as area under the time course curve). H. virginiana was inactive and G. Officinale was only active at 200 mg kg−1. At 200 mg kg−1 administered before the induction of adjuvant arthritis, P. bistorta significantly inhibited both the acute and chronic phases of the adjuvant-induced rat paw swelling, while G. Officinale and H. virginiana were only active against the chronic phase. Further studies on P. bistorta (100–800 mg kg−1) revealed a dose-dependent inhibition of the carrageenan-induced rat paw oedema over the dose range 100–400 mg kg−1, the E50 value being approximately 158·5 mg kg−1. The extract (200 mg kg−1), administered after the onset of the inflammatory responses reversed the course of both the carrageenan- and adjuvant- induced rat paw swelling. The results confirm that the extracts of P. bistorta, G. Officinale and H. virginiana contain anti-inflammatory substances.
I. J. Zeitlin - One of the best experts on this subject based on the ideXlab platform.
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anti inflammatory activity of polygonum bistorta Guaiacum Officinale and hamamelis virginiana in rats
Journal of Pharmacy and Pharmacology, 1994Co-Authors: M. Duwiejua, I. J. Zeitlin, Peter G. Waterman, Alexander I. GrayAbstract:The aqueous ethanolic extracts of Polygonum bistorta L. Polygonaceae, Guaiacum Officinale L. Zygophyllaceae and Hamamelis virginiana L. Hamamelidaceae were screened for anti-inflammatory activity. Administered (100 and 200 mg kg-1, p.o.) before the induction of carrageenan rat paw oedema, extracts of P. bistorta significantly suppressed both the maximal oedema response and the total oedema response (monitored as area under the time course curve). H. virginiana was inactive and G. Officinale was only active at 200 mg kg-1. At 200 mg kg-1 administered before the induction of adjuvant arthritis, P. bistorta significantly inhibited both the acute and chronic phases of the adjuvant-induced rat paw swelling, while G. Officinale and H. virginiana were only active against the chronic phase. Further studies on P. bistorta (100-800 mg kg-1) revealed a dose-dependent inhibition of the carrageenan-induced rat paw oedema over the dose range 100-400 mg kg-1, the E50 value being approximately 158.5 mg kg-1. The extract (200 mg kg-1), administered after the onset of the inflammatory responses reversed the course of both the carrageenan- and adjuvant-induced rat paw swelling. The results confirm that the extracts of P. bistorta, G. Officinale and H. virginiana contain anti-inflammatory substances.
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Anti‐inflammatory Activity of Polygonum bistorta, Guaiacum Officinale and Hamamelis virginiana in Rats
The Journal of pharmacy and pharmacology, 1994Co-Authors: M. Duwiejua, I. J. Zeitlin, Peter G. Waterman, Alexander I. GrayAbstract:Abstract— The aqueous ethanolic extracts of Polygonum bistorta L. Polygonaceae, Guaiacum Officinale L. Zygophyllaceae and Hamamelis virginiana L. Hamamelidaceae were screened for anti-inflammatory activity. Administered (100 and 200 mg kg−1, p.o.) before the induction of carrageenan rat paw oedema, extracts of P. bistorta significantly suppressed both the maximal oedema response and the total oedema response (monitored as area under the time course curve). H. virginiana was inactive and G. Officinale was only active at 200 mg kg−1. At 200 mg kg−1 administered before the induction of adjuvant arthritis, P. bistorta significantly inhibited both the acute and chronic phases of the adjuvant-induced rat paw swelling, while G. Officinale and H. virginiana were only active against the chronic phase. Further studies on P. bistorta (100–800 mg kg−1) revealed a dose-dependent inhibition of the carrageenan-induced rat paw oedema over the dose range 100–400 mg kg−1, the E50 value being approximately 158·5 mg kg−1. The extract (200 mg kg−1), administered after the onset of the inflammatory responses reversed the course of both the carrageenan- and adjuvant- induced rat paw swelling. The results confirm that the extracts of P. bistorta, G. Officinale and H. virginiana contain anti-inflammatory substances.
Oberlin Christine - One of the best experts on this subject based on the ideXlab platform.
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Datations radiocarbone et "effet vieux bois" dans l'arc antillais : état de la question
'Associacao Educacional de Vitoria', 2015Co-Authors: Stouvenot Christian, Beauchêne Jacques, Bonnissent Dominique, Oberlin ChristineAbstract:Parmi les nombreux effets susceptibles de fausser l'interprétation des datations par le radiocarbone, figurent ceux pour lesquels l'âge de l'événement archéologique est différent de l'âge radiocarbone de l'échantillon, ou âge de l'" événement radiocarbone ". Ce type de problème se pose dans de nombreux cas, en particulier celui dénommé " effet vieux bois ". Cette question est prise en compte dans diverses régions du monde où des espèces végétales très longévives sont fréquentes. Dans les Antilles les études anthracologiques disponibles indiquent une fréquence très importante de certaines espèces autochtones multiséculaires dont le gaïac, Guaiacum Officinale L.. Cependant, la quasi absence de données dendrochronologiques dans la zone tropicale humide, nous privent d'un inventaire précis des espèces longévives et surtout de l'évaluation de leur longévité. Quelques tests présentés ici ont permis une estimation de la longévité de poteaux d'origine archéologique en bois de gaïac. Ils mettent en évidence un décalage de plusieurs siècles entre les parties externes et le coeur du tronc. Cet exemple illustre l'apparition d'une incertitude supplémentaire dans la datation de l'événement archéologique lorsque que l'on ne connaît ni l'espèce botanique ni la zone de prélèvement dans l'arbre. Une autre source d'erreur pourrait provenir de l'utilisation de bois mort de qualité très durable comme combustible, sachant que les grands cyclones peuvent produire d'importantes quantités de bois mort susceptible d'être récolté pendant des décennies, voire des siècles. Afin d'améliorer les données chronologiques utilisées dans les interprétations archéologiques, il apparaît nécessaire de s'assurer de la qualité des datations, et donc de suivre un protocole similaire à ceux utilisés dans d'autres régions basé sur une meilleure connaissance des éléments datés : espèce, partie anatomique, humidité du bois utilisé (vert ou sec). (Résumé d'auteur
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Datations radiocarbone et le « problème vieux bois » dans l’arc antillais : état de la question
HAL CCSD, 2013Co-Authors: Stouvenot Christian, Beauchêne Jacques, Bonnissent Dominique, Oberlin ChristineAbstract:International audienceRadiocarbon dating and "old wood problem" in the Antilles : the state of the artAmong the many effects that may distort the interpretation of radiocarbon dates are those for which the age of the archaeological event is different from the radiocarbon age of the sample or "14C event" age. This type of problem arises in many cases, notably in the "old wood effect”, and occurs in various regions of the world where very long-lived trees species are common. In the Caribbean anthracological studies indicate a very high frequency of some indigenous centuries-old species such as Guaiacum, Guaiacum Officinale L. However the absence of tree-ring data in humid tropical zones deprives us of an accurate inventory of long-lived species and especially the assessment of their longevity. Here we present measurements which enable us to estimate the longevity of archaeological Guaiacum wood posts. They highlight a gap of several centuries between wood from the outer edge and the heart of the tree. This example illustrates the additional uncertainty that can result from dating archeological events when dates are realized on unidentified botanical species from which the area that was sampled is unknown. Another source of error could arise from the use of rot-proof dead wood as fuel if we take into consideration that major hurricanes can produce large amounts of dead wood that may be collected for decades, even centuries. To improve chronometric data used in archaeological interpretations, it is necessary to ensure the quality of the dating process by following a protocol similar to those used in other regions of the world based on a better understanding of the material to be dated by preliminary identifications of wood samples: species, anatomical part, wood moisture content (unseasoned or seasoned).Radiocarbono y "problema madera vieja", que data de las Antillas: estado del arteEntre los muchos efectos que pueden distorsionar la interpretación de fechas de radiocarbono, destacan aquellos para los que la edad de la prueba arqueológica es diferente de la edad de radiocarbono de la muestra, o la edad del "evento de radiocarbono." Este tipo de problema se presenta en muchos casos, especialmente uno llamado "efecto madera vieja." Esto se refleja en diversas regiones del mundo donde las especies de plantas de mucha longevidad son comunes. En el Caribe, los estudios antracológicos disponibles indican una muy alta frecuencia de algunas especies autóctonas como el guayaco, Guaiacum Officinale L. Sin embargo, la casi ausencia de datos de anillos de árboles en los trópicos húmedos, nos impide realizar un inventario exacto de especies de mucha longevidad y sobre todo la evaluación de la longevidad. Algunas de las pruebas presentadas aquí permitieron una estimación de la longevidad de de unos postes de guayaco de origen arqueológico. Ponen de manifiesto una brecha de varios siglos entre las partes externas y el corazón del tronco. Este ejemplo ilustra la aparición de una incertidumbre adicional en la datación de los eventos arqueológicos cuando no conocemos la especie botánica y tampoco la zona de la muestra en el árbol. Otra fuente de error puede surgir de la utilización de la madera muerta de calidad duradera como combustible ya que los grandes huracanes pueden producir grandes cantidades de madera muerta, que puede ser requerida durante décadas, incluso siglos. Para mejorar los datos cronométricos utilizados en interpretaciones arqueológicas, es necesario asegurarse de la calidad de las fechas, y por lo tanto seguir un protocolo similar a los utilizados en otras regiones fundado en una mejor comprensión de los elementos: especie, parte anatómica, humedad de la madera usada (verde o seco).Parmi les nombreux effets susceptibles de fausser l’interprétation des datations par le radiocarbone, figurent ceux pour lesquels l’âge de l’événement archéologique est différent de l’âge radiocarbone de l’échantillon, ou âge de l’« événement radiocarbone ». Ce type de problème se pose dans de nombreux cas, en particulier celui dénommé « effet vieux bois ». Cette question est prise en compte dans diverses régions du monde où des espèces végétales très longévives sont fréquentes. Dans les Antilles les études anthracologiques disponibles indiquent une fréquence très importante de certaines espèces autochtones multiséculaires dont le gaïac, Guaiacum Officinale L.. Cependant, la quasi absence de données dendrochronologiques dans la zone tropicale humide, nous privent d’un inventaire précis des espèces longévives et surtout de l’évaluation de leur longévité. Quelques tests présentés ici ont permis une estimation de la longévité de poteaux d’origine archéologique en bois de gaïac. Ils mettent en évidence un décalage de plusieurs siècles entre les parties externes et le cœur du tronc. Cet exemple illustre l’apparition d’une incertitude supplémentaire dans la datation de l’événement archéologique lorsque que l’on ne connaît ni l’espèce botanique ni la zone de prélèvement dans l’arbre. Une autre source d’erreur pourrait provenir de l’utilisation de bois mort de qualité très durable comme combustible, sachant que les grands cyclones peuvent produire d’importantes quantités de bois mort susceptible d’être récolté pendant des décennies, voire des siècles. Afin d’améliorer les données chronologiques utilisées dans les interprétations archéologiques, il apparaît nécessaire de s’assurer de la qualité des datations, et donc de suivre un protocole similaire à ceux utilisés dans d’autres régions basé sur une meilleure connaissance des éléments datés : espèce, partie anatomique, humidité du bois utilisé (vert ou sec)
