The Experts below are selected from a list of 10146 Experts worldwide ranked by ideXlab platform

Nanees Salem - One of the best experts on this subject based on the ideXlab platform.

  • Prepubertal Gynecomastia is not always idiopathic: case series and review of the literature
    European Journal of Pediatrics, 2020
    Co-Authors: Wafaa Laimon, Amany El-hawary, Hadil Aboelenin, Mohamed Elzohiri, Sherif Abdelmaksoud, Nirmeen Megahed, Nanees Salem
    Abstract:

    Although pubertal Gynecomastia is a common clinical presentation of adolescent males, prepubertal Gynecomastia is uncommon and mostly idiopathic. However, pathological causes of prepubescent Gynecomastia are encountered in clinical practice. This manuscript carries an important message to general pediatricians, to care about exclusion of pathological causes for every patient of prepubertal Gynecomastia. We present four different patients with pathological Gynecomastia. One of them revealed to be secondary to Sertoli cell tumor, while the second patient describes trauma as a rare cause of prepubertal true Gynecomastia. To the best of our knowledge, this is the first time to report occupational trauma as a cause of true Gynecomastia as confirmed by pathological specimen, in a prepubertal boy. The third patient presented with retro-areolar mass and bloody nipple discharge secondary to mammary duct ectasia and had favorable self-limited course. Hyperprolactinemia secondary to neglected congenital hypothyroidism was the cause beyond Gynecomastia in the fourth patient and this cause has been reported only once in the literature. Conclusion : Despite being rare, pathological causes of prepubertal Gynecomastia are encountered in clinical practice, and full investigations including breast and testicular ultrasound are needed to exclude any pathology before diagnosing idiopathic Gynecomastia. Repeated friction of the breast can lead to true Gynecomastia not only to pseudoGynecomastia as previously known. What is Known: • It has been reported that trauma can cause pseudoGynecomastia due to hematoma or fat necrosis. • Prepubertal Gynecomastia is mostly idiopathic. What is New: • Long-term breast trauma can cause true Gynecomastia (adenosis). • Although being mostly idiopathic, pathological causes of prepubertal Gynecomastia must be ruled out.

Swenolof Andersson - One of the best experts on this subject based on the ideXlab platform.

  • prophylactic breast irradiation with a single dose of electron beam radiotherapy 10 gy significantly reduces the incidence of bicalutamide induced Gynecomastia
    International Journal of Radiation Oncology Biology Physics, 2004
    Co-Authors: Christopher J Tyrrell, Heather Payne, Teuvo L J Tammela, August Bakke, Par Lodding, Louis Goedhals, Peter Van Erps, Tom A Boon, Cees Van De Beek, Swenolof Andersson
    Abstract:

    Abstract Purpose To evaluate the efficacy and tolerability of prophylactic breast irradiation in reducing the incidence and severity of bicalutamide-induced Gynecomastia and breast pain. Methods and materials In all, 106 men with prostate cancer (T1b–T4/Nx/M0) and no current Gynecomastia/breast pain were enrolled in this randomized, sham-controlled, double-blind, parallel-group multicenter trial. Patients received either a single dose of electron beam radiotherapy (10 Gy) or sham radiotherapy. Bicalutamide (Casodex) 150 mg/day was administered for 12 months from the day of radiotherapy. Every 3 months, patients underwent physical examination and questioning about Gynecomastia and breast pain. Results The incidence of investigator-assessed Gynecomastia was significantly lower with radiotherapy vs. sham radiotherapy (52% vs. 85%; odds ratio [OR], 0.13; 95% confidence interval [CI], 0.04, 0.38; p p = 0.221); patients receiving radiotherapy experienced some reduction in its severity (OR, 0.44; 95% CI, 0.20, 0.97; p = 0.0429). Conclusions Prophylactic breast irradiation is an effective and well-tolerated strategy for prevention of bicalutamide-induced Gynecomastia.

Abraham Ohry - One of the best experts on this subject based on the ideXlab platform.

  • Gynecomastia following spinal cord disorder
    Archives of physical medicine and rehabilitation, 1997
    Co-Authors: Rephael J. Heruti, Rachel Dankner, Meir Berezin, G. Zeilig, Abraham Ohry
    Abstract:

    Gynecomastia, an excessive development of the mammary glands in men, is a known phenomenon among patients with spinal cord disorder, yet in the last 50 years it has not been fully described in relation to spinal cord disorder. Over a period of 2 years, six patients with spinal cord disorder (4 secondary to a traumatic injury, 1 to decompression sickness, and 1 to transverse myelitis) manifested Gynecomastia. The onset of Gynecomastia occurred between 1 to 6 months after injury. These patients are presented along with a review of the possible causes for Gynecomastia and a suggested workup routine. A clinical examination for the presence of Gynecomastia should be performed for every patient with spinal cord disorder and a thorough endocrinological workup should follow to rule out malignancy and reassure the anxious patient undergoing a disruption of his body image.

Mihai A Constantinescu - One of the best experts on this subject based on the ideXlab platform.

  • surgical management of Gynecomastia a 10 year analysis
    World Journal of Surgery, 2008
    Co-Authors: A E Handschin, D Bietry, R Husler, Andrej Banic, Mihai A Constantinescu
    Abstract:

    BACKGROUND: Gynecomastia is defined as the benign enlargement of the male breast. Most studies on surgical treatment of Gynecomastia show only small series and lack histopathology results. The aim of this study was to analyze the surgical approach in the treatment of Gynecomastia and the related outcome over a 10-year period. PATIENTS AND METHODS: All patients undergoing surgical Gynecomastia corrections in our department between 1996 and 2006 were included for retrospective evaluation. The data were analyzed for etiology, stage of Gynecomastia, surgical technique, complications, risk factors, and histological results. RESULTS: A total of 100 patients with 160 operations were included. Techniques included subcutaneous mastectomy alone or with additional hand-assisted liposuction, isolated liposuction, and formal breast reduction. Atypical histological findings were found in 3% of the patients (spindle-cell hemangioendothelioma, papilloma). The surgical revision rate among all patients was 7%. Body mass index and a weight of the resected specimen higher than 40 g were identified as significant risk factors for complications (p < 0.05). CONCLUSIONS: The treatment of Gynecomastia requires an individualized approach. Caution must be taken in performing large resections, which are associated with increased complication rates. Histological tissue analysis should be routinely performed in all true Gynecomastia corrections, because histological results may reveal atypical cellular pathology.

Jun-ichi Kira - One of the best experts on this subject based on the ideXlab platform.

  • Autosomal dominant familial spinal and bulbar muscular atrophy with Gynecomastia
    Neurology, 1999
    Co-Authors: Koji Ikezoe, Kazunari Nagamatsu, Takesumi Yoshimura, Hirokazu Furuya, E Matsuura, Takayuki Taniwaki, Takeshi Yamada, Jun-ichi Kira
    Abstract:

    Article abstract The proband, a 53-year-old man, developed progressive spinal and bulbar muscular atrophy and Gynecomastia at the age of 50. His father had weakness of lower limbs, and his son had a nasal voice, ocular movement abnormalities, and Gynecomastia, whereas two of the proband’s brothers showed either Gynecomastia or tongue fasciculations. None of the patients showed any expansion of CAG repeat in the androgen receptor gene or any hormonal abnormality. Thus, this family is affected by a form of autosomal dominant spinal and bulbar muscular atrophy with Gynecomastia.