The Experts below are selected from a list of 78 Experts worldwide ranked by ideXlab platform
Shigeru Kinoshita - One of the best experts on this subject based on the ideXlab platform.
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impact of high myopia and duration of Hard Contact Lens wear on the progression of ptosis
Japanese Journal of Ophthalmology, 2013Co-Authors: Akihide Watanabe, Kojiro Imai, Shigeru KinoshitaAbstract:To investigate the impact of myopia and duration of Hard Contact Lens (HCL) wear on the progression of ptosis. This study involved 194 eyes of 98 patients with either bilateral or unilateral ptosis with long-term HCL wear. The ptosis of each eyelid was classified into 1 of 4 grades (no ptosis, mild, moderate and severe), and the average spherical equivalent refractive error (SERE), patient age and the duration of HCL wear were then examined. The average SERE (in diopters) in 99 severe eyes was −8.34, in 47 moderate eyes, −6.28, in 37 mild eyes −5.57 and in 11 no ptosis eyes, −4.80, while the average duration of HCL wear (in years) were 34, 30, 29, and 31, respectively. The average SERE was significantly higher in the severe than in the moderate, mild and no ptosis eyelids, and the average duration of HCL wear was significantly longer in the severe than in the moderate and mild ptosis eyelids. Path analysis showed that the severity of ptosis is significantly influenced by SERE, as well as by patient age and the duration of HCL wear. High myopia, patient age and long-term HCL wear are risk factors associated with the progression of ptosis.
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histopathology of blepharoptosis induced by prolonged Hard Contact Lens wear
American Journal of Ophthalmology, 2006Co-Authors: Akihide Watanabe, Biji Araki, Kenji Noso, Hirohiko Kakizaki, Shigeru KinoshitaAbstract:Purpose To clarify histopathologically the structural features of blepharoptosis in prolonged Hard Contact Lens wearers. Design Retrospective case-control study. Methods Biopsy specimens from identical sites at the levator aponeurosis and Mueller muscle from 15 long-term Hard Contact Lens wearers were examined histopathologically (group 1). They comprised two men and 13 women with bilateral blepharoptosis ranging in age from 26 to 59 years (mean ± SD, 44.4 ± 10.70 years). The average length of Hard Contact Lens wear was 25.4 years (range 12 to 40 years), and the average spherical equivalent refractive error was −9.100 diopters (range −2.825 to −20.375 diopters). We also examined specimens from 15 patients with involutional blepharoptosis who underwent levator resection; they comprised three men and 12 women ranging in age from 64 to 79 years (mean ± SD, 72.3 ± 4.38 years). Results All patients in group 1 manifested fibrosis and negligible fatty degeneration in Mueller muscle. In group 2, we detected mild fibrosis in Mueller muscle and fatty degeneration of the aponeurosis and Mueller muscle. Conclusions Prolonged Hard Contact Lens wear induces fibrosis in Mueller muscle and may result in Contact Lens–induced blepharoptosis.
Hans G Lemij - One of the best experts on this subject based on the ideXlab platform.
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blepharoptosis induced by prolonged Hard Contact Lens wear
Ophthalmology, 1992Co-Authors: Willem A Van Den Bosch, Hans G LemijAbstract:Purpose: The authors attempt to establish a relation between Hard Contact Lens wear and upper eyelid ptosis. Methods: This study consists of two parts. In the first part, the authors compare the unilateral or bilateral ptosis that developed during Hard Contact Lens wear in 17 patients with the involutional ptosis that developed in another group of 73 patients. In the second part, the authors compare both upper and lower eyelid position in 46 patients who had been wearing Hard Contact Lenses for at least 10 years with the position of 50 matched controls who had never worn Contact Lenses. Results: The ptosis that had developed in the 17 patients who wore Hard Contact Lenses was clinically similar to that caused by involutional levator disinsertion. The second part of the study shows that the prolonged wearers of Hard Contact Lenses had upper eyelids that were lower by approximately 0.5 mm when compared with control subjects. This difference is statistically significant. According to standard criteria, there were at least 10 ptotic eyelids in the Contact Lens group versus 1 in the control group. Conclusion: The study findings suggest that prolonged Hard Contact Lens wear may induce a lower position of the upper eyelid and eventually lead to ptosis through levator disinsertion.
Gregory Kracher - One of the best experts on this subject based on the ideXlab platform.
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specular microscopy studies on the corneal endothelium after cessation of Contact Lens wear
Cornea, 1991Co-Authors: Maria Elena Sibug, Manuel B Datiles, K Kashima, Lessie Mccain, Gregory KracherAbstract:: We performed specular microscopy on the corneal endothelium of 22 long-term Hard Contact Lens wearers (15-32 years duration) and 22 age- and sex-matched controls. We found polymegethism in users as shown by a significant difference in the coefficient of variation in cell area (p less than 0.01) and pleomorphism as shown by a significant decrease in the percent of 6-sided cells (hexagonality, p less than 0.01). There was no significant difference in cell density and mean cell area between the 2 groups. Contact Lens wear was discontinued in five eyes of three patients after they were entered into the study and switched to eye-glasses. Specular micrographs were taken up to 60 months after discontinuation of use of the Lenses. Comparison of the above parameters before and after discontinuation of the Lenses did not show a significant change. However, there was a trend toward improvement in the coefficient of variation in the eyes that were followed the longest. This finding suggests that the morphological changes induced by long-term use of Contact Lenses may be slowly reversible after prolonged discontinuation of Contact Lens wear.
Willem A Van Den Bosch - One of the best experts on this subject based on the ideXlab platform.
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not only Hard Contact Lens wear but also soft Contact Lens wear may be associated with blepharoptosis
Canadian Journal of Ophthalmology-journal Canadien D Ophtalmologie, 2011Co-Authors: Isabel Bleyen, Coen A Hiemstra, Thibaut Devogelaere, Willem A Van Den Bosch, Rene J Wubbels, Dion ParidaensAbstract:Abstract Objective The authors attempt to establish an association between prolonged Hard and soft Contact Lens wear and ptosis. Design Single-center retrospective consecutive series. Participants All patients between 18 and 50 years of age who were diagnosed with unilateral or bilateral ptosis between January 2002 and December 2005 (35 patients). Methods In a retrospective consecutive series, we included all patients between 18 and 50 years of age, with unilateral or bilateral ptosis between January 2002 and December 2005. Patients with congenital ptosis, ophthalmic surgery or disease, trauma, giant papillary conjunctivitis, unknown duration of Contact Lens wear, or muscular or neurologic disorders were excluded. We compared this study group to a Dutch reference population (the total underlying population from which the ptosis cases derive). Results The group included 35 patients: 20 (57%) (ages 18 to 50 years, average 37 years) had been wearing Hard Contact Lenses for, on average, 17.6 years (range 6 to 27 years); 9 (26%) (ages 18 to 45 years, average 30 years) had been wearing soft Contact Lenses for, on average, 9 years (range 1.5 to 20 years); and 6 (17%) (ages 23 to 39 years, average 33 years) had no history of Contact Lens wear. The odds ratio for soft Contact Lenses was 14.7 (4.2 to 50.7; CI = 95) and for Hard Contact Lenses 97.8 (22.5 to 424). Conclusions This study suggests that not only Hard Contact Lens wear but also soft Contact Lens wear may be associated with ptosis.
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blepharoptosis induced by prolonged Hard Contact Lens wear
Ophthalmology, 1992Co-Authors: Willem A Van Den Bosch, Hans G LemijAbstract:Purpose: The authors attempt to establish a relation between Hard Contact Lens wear and upper eyelid ptosis. Methods: This study consists of two parts. In the first part, the authors compare the unilateral or bilateral ptosis that developed during Hard Contact Lens wear in 17 patients with the involutional ptosis that developed in another group of 73 patients. In the second part, the authors compare both upper and lower eyelid position in 46 patients who had been wearing Hard Contact Lenses for at least 10 years with the position of 50 matched controls who had never worn Contact Lenses. Results: The ptosis that had developed in the 17 patients who wore Hard Contact Lenses was clinically similar to that caused by involutional levator disinsertion. The second part of the study shows that the prolonged wearers of Hard Contact Lenses had upper eyelids that were lower by approximately 0.5 mm when compared with control subjects. This difference is statistically significant. According to standard criteria, there were at least 10 ptotic eyelids in the Contact Lens group versus 1 in the control group. Conclusion: The study findings suggest that prolonged Hard Contact Lens wear may induce a lower position of the upper eyelid and eventually lead to ptosis through levator disinsertion.
Carla P. Nieuwendaal - One of the best experts on this subject based on the ideXlab platform.
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A conjunctival mass in the deep superior fornix after a long retained Hard Contact Lens in a patient with keloids.
Cornea, 2008Co-Authors: Enrica Zola, Ivanka J E Van Der Meulen, Ruth Lapid-gortzak, J Mj Van Vliet, Carla P. NieuwendaalAbstract:Purpose: To report a case of an upper eyelid mass induced by a rigid Contact Lens retained for more than 3 years in the eye of a patient with a general history of keloids and to provide a review of the literature on retained Contact Lenses. Methods: Case report. Results: A 45-year-old woman with an ophthalmologic history of dry eyes and follicular chronic conjunctivitis presented at our department complaining of irritation, mucous discharge, and Contact Lens intolerance in her left eye. The ophthalmic examination revealed a visual acuity of 20/20 in both eyes and bilateral blepharitis. A pseudoptosis and an impressive mass growing from the superior tarsal conjunctiva with a lot of mucous discharge were present in the left eye. After a delay of 3.5 years with persisting complaints, a double lid eversion revealed the presence of a Hard Contact Lens retained in the deep fornix of the left eye. After removing the Lens and a short period of treatment with local corticosteroids, the mass and the symptoms disappeared. Conclusions: in patients who wear or wore Contact Lenses and present with one-sided chronic irritation and tissue proliferation, the possibility of a retained Contact Lens should be considered. The previous history of dry eyes and chronic conjunctivitis led us to miss the diagnosis at the first visits, despite persisting complaints. No other cases about the effects of a retained Contact Lens in a patient with keloids have been previously reported
