The Experts below are selected from a list of 1620 Experts worldwide ranked by ideXlab platform
Dong Ho Lee - One of the best experts on this subject based on the ideXlab platform.
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Assessment of Fluid Space after Infusion of Hartmann's Solution and Hydroxethyl Starch Solutions during General Anesthesia
Korean Journal of Anesthesiology, 2008Co-Authors: Su Jin Kang, Kyu Taek Choi, Ji Hee Lee, Dong Ho LeeAbstract:Background: Distribution and elimination of crystalloid or colloid Solutions during inhalational anesthesia have not been adequately investigated. Hemoglobin dilution and fluid kinetic model have been shown to reveal the distribution and elimination of various kinds of fluids. Therefore, we assessed fluid space changes after Hartmann’s Solution or hydroxyethyl starch Solution (HES) infusion during desflurane anesthesia. Methods: We infused 20 ml/kg of Hartmann’s Solution, 8.5 ml/kg of Hextend Ⓡ and 8.5 ml/kg of Voluven Ⓡ during 20 min, after anesthesia induction and before surgical incision, and measured the hemoglobin changes. We used mass balance equations and a fluid kinetic model to evaluate the changes of fluid space. In the fluid kinetic model, we used one volume model, which allows estimation of the size of the body fluid space expanded by the fluid (V) and the elimination rate constant (kr). Results: The expanded plasma volume of three different fluids, calculated using mass balance equations, showed a similar degree of expansion during infusion, however, after finishing infusion, the dilution effect of Hartmann’s Solution decreased rapidly and lasted less than HES. Fluid kinetic model shows the mean size of V of 12.3 ± 5.9 L for Hartmann’ Solution, 5.2 ± 1.6 L for Hextend, and 4.5 ± 1.6 L for Voluven. Corresponding kr values were 263.0 ± 161.8, 36.5 ± 31.8, and 34.1 ± 21.3 ml/min, respectively. Conclusions: The distribution volume of intravenous fluids analyzed by kinetic model showed that crystalloid fluid has a similar volume distribution compared to extracellular fluid and HES distributed to a volume larger than blood volume. Analysis and simulation of plasma volume expansion using this model provide a helpful tool for anesthesiologists planning fluid therapy.
Su Jin Kang - One of the best experts on this subject based on the ideXlab platform.
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Assessment of Fluid Space after Infusion of Hartmann's Solution and Hydroxethyl Starch Solutions during General Anesthesia
Korean Journal of Anesthesiology, 2008Co-Authors: Su Jin Kang, Kyu Taek Choi, Ji Hee Lee, Dong Ho LeeAbstract:Background: Distribution and elimination of crystalloid or colloid Solutions during inhalational anesthesia have not been adequately investigated. Hemoglobin dilution and fluid kinetic model have been shown to reveal the distribution and elimination of various kinds of fluids. Therefore, we assessed fluid space changes after Hartmann’s Solution or hydroxyethyl starch Solution (HES) infusion during desflurane anesthesia. Methods: We infused 20 ml/kg of Hartmann’s Solution, 8.5 ml/kg of Hextend Ⓡ and 8.5 ml/kg of Voluven Ⓡ during 20 min, after anesthesia induction and before surgical incision, and measured the hemoglobin changes. We used mass balance equations and a fluid kinetic model to evaluate the changes of fluid space. In the fluid kinetic model, we used one volume model, which allows estimation of the size of the body fluid space expanded by the fluid (V) and the elimination rate constant (kr). Results: The expanded plasma volume of three different fluids, calculated using mass balance equations, showed a similar degree of expansion during infusion, however, after finishing infusion, the dilution effect of Hartmann’s Solution decreased rapidly and lasted less than HES. Fluid kinetic model shows the mean size of V of 12.3 ± 5.9 L for Hartmann’ Solution, 5.2 ± 1.6 L for Hextend, and 4.5 ± 1.6 L for Voluven. Corresponding kr values were 263.0 ± 161.8, 36.5 ± 31.8, and 34.1 ± 21.3 ml/min, respectively. Conclusions: The distribution volume of intravenous fluids analyzed by kinetic model showed that crystalloid fluid has a similar volume distribution compared to extracellular fluid and HES distributed to a volume larger than blood volume. Analysis and simulation of plasma volume expansion using this model provide a helpful tool for anesthesiologists planning fluid therapy.
Ji Hee Lee - One of the best experts on this subject based on the ideXlab platform.
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Assessment of Fluid Space after Infusion of Hartmann's Solution and Hydroxethyl Starch Solutions during General Anesthesia
Korean Journal of Anesthesiology, 2008Co-Authors: Su Jin Kang, Kyu Taek Choi, Ji Hee Lee, Dong Ho LeeAbstract:Background: Distribution and elimination of crystalloid or colloid Solutions during inhalational anesthesia have not been adequately investigated. Hemoglobin dilution and fluid kinetic model have been shown to reveal the distribution and elimination of various kinds of fluids. Therefore, we assessed fluid space changes after Hartmann’s Solution or hydroxyethyl starch Solution (HES) infusion during desflurane anesthesia. Methods: We infused 20 ml/kg of Hartmann’s Solution, 8.5 ml/kg of Hextend Ⓡ and 8.5 ml/kg of Voluven Ⓡ during 20 min, after anesthesia induction and before surgical incision, and measured the hemoglobin changes. We used mass balance equations and a fluid kinetic model to evaluate the changes of fluid space. In the fluid kinetic model, we used one volume model, which allows estimation of the size of the body fluid space expanded by the fluid (V) and the elimination rate constant (kr). Results: The expanded plasma volume of three different fluids, calculated using mass balance equations, showed a similar degree of expansion during infusion, however, after finishing infusion, the dilution effect of Hartmann’s Solution decreased rapidly and lasted less than HES. Fluid kinetic model shows the mean size of V of 12.3 ± 5.9 L for Hartmann’ Solution, 5.2 ± 1.6 L for Hextend, and 4.5 ± 1.6 L for Voluven. Corresponding kr values were 263.0 ± 161.8, 36.5 ± 31.8, and 34.1 ± 21.3 ml/min, respectively. Conclusions: The distribution volume of intravenous fluids analyzed by kinetic model showed that crystalloid fluid has a similar volume distribution compared to extracellular fluid and HES distributed to a volume larger than blood volume. Analysis and simulation of plasma volume expansion using this model provide a helpful tool for anesthesiologists planning fluid therapy.
Kyu Taek Choi - One of the best experts on this subject based on the ideXlab platform.
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Assessment of Fluid Space after Infusion of Hartmann's Solution and Hydroxethyl Starch Solutions during General Anesthesia
Korean Journal of Anesthesiology, 2008Co-Authors: Su Jin Kang, Kyu Taek Choi, Ji Hee Lee, Dong Ho LeeAbstract:Background: Distribution and elimination of crystalloid or colloid Solutions during inhalational anesthesia have not been adequately investigated. Hemoglobin dilution and fluid kinetic model have been shown to reveal the distribution and elimination of various kinds of fluids. Therefore, we assessed fluid space changes after Hartmann’s Solution or hydroxyethyl starch Solution (HES) infusion during desflurane anesthesia. Methods: We infused 20 ml/kg of Hartmann’s Solution, 8.5 ml/kg of Hextend Ⓡ and 8.5 ml/kg of Voluven Ⓡ during 20 min, after anesthesia induction and before surgical incision, and measured the hemoglobin changes. We used mass balance equations and a fluid kinetic model to evaluate the changes of fluid space. In the fluid kinetic model, we used one volume model, which allows estimation of the size of the body fluid space expanded by the fluid (V) and the elimination rate constant (kr). Results: The expanded plasma volume of three different fluids, calculated using mass balance equations, showed a similar degree of expansion during infusion, however, after finishing infusion, the dilution effect of Hartmann’s Solution decreased rapidly and lasted less than HES. Fluid kinetic model shows the mean size of V of 12.3 ± 5.9 L for Hartmann’ Solution, 5.2 ± 1.6 L for Hextend, and 4.5 ± 1.6 L for Voluven. Corresponding kr values were 263.0 ± 161.8, 36.5 ± 31.8, and 34.1 ± 21.3 ml/min, respectively. Conclusions: The distribution volume of intravenous fluids analyzed by kinetic model showed that crystalloid fluid has a similar volume distribution compared to extracellular fluid and HES distributed to a volume larger than blood volume. Analysis and simulation of plasma volume expansion using this model provide a helpful tool for anesthesiologists planning fluid therapy.
Dino Mario - One of the best experts on this subject based on the ideXlab platform.
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efecto de la fluido terapia endovenosa en los electrolitos y gases arteriales de pacientes ancianos hospitalizados estudio comparativo solucion Hartmann y solucion salina hipotonica effect of intravenous therapy on the electrolytes and arterial blood
2006Co-Authors: Malaga Rodriguez, German Javier, Pino Velasco, Dino MarioAbstract:SUMMARY Objective: To compare the effect of hypotonic dextrose Solution vs. isotonic Hartmann Solution on serum electrolytes and acid-base equilibrium in elderly hospitalized patients. Patients and methods: Eighteen patients over 60-years old, admitted to medicine department of the Hospital Nacional Cayetano Heredia and received intravenous fluids during 48 hours, were prospectively evaluated. Control cohort received a Solution of 5% dextrose, 71 mmol/L of sodium chloride, and 27 mmol/L of potassium chloride. Experimental cohort received Hartmann's Solution plus 100 cc of 50% dextrose Solution. The electrolytes and blood gas levels were measured at hours 0, 24, and 48. Results: Electrolyte levels and the acid-base equilibrium were similar for both cohorts at the beginning of study. After 48 hours we observed significant differences between cohorts in the sodium (G1=134.5±4.4, G2=140±2.4, p<0.01), pH (G1=7.32±0.07, G2=7.4±0.03, p<0.01), and bicarbonate (G1=16.6±2.2, G2=22.3±1.6, p<0.001) levels. The differences between the values at hours 0 and 48 (delta) were: sodium -6.1±3.78(G1), 0.9±2.25(G2) mEq/l, (p<0.001); potassium 0.01±0.43(G1), -0.61±0.56(G2) mEq/L, (p=0.05); pH -0.09±0.07(G1), -0.01±0.04(G2), (p<0.01); bicarbonate -6.34±1.21(G1), -0.27±1.43(G2) mEq/L, (p<0.001); pCO2 -6.25±5.33(G1), 1.4±4.52(G2) mmHg, (p<0.01). Conclusions: Elderly hospitalized patients who received hypotonic dextrose Solution had significantly lower plasma sodium, pH, bicarbonate, and pCO 2 levels after 48 hours of intravenous fluid therapy as compared with patients who received Hartmann's Solution. No significant differences in chloride, pO 2 , and anion gap serum levels were observed. (Rev Med Hered 2006;17:189-195).
