The Experts below are selected from a list of 55932 Experts worldwide ranked by ideXlab platform
Matthew J. Olnes - One of the best experts on this subject based on the ideXlab platform.
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gastric cancer in alaska native people a cancer Health Disparity
World Journal of Gastroenterology, 2018Co-Authors: Holly A. Martinson, Steven R Alberts, Nancy J Shelby, Matthew J. OlnesAbstract:AIM To evaluate recent trends in gastric cancer incidence, response to treatment, and overall survival among Alaska Native (AN) people. METHODS A retrospective analysis of the Alaska Native Medical Center patient database was performed. Patient history, clinical, pathological, response to treatment and patient outcomes were collected from one-hundred and thirty-two AN gastric cancer patients. The Surveillance, Epidemiology and End Result database 18 was used to collect comparison United States non-Hispanic White (NHW) and AN gastric cancer patient data between 2006-2014. RESULTS AN gastric cancer patients have a higher incidence rate, a poorer overall survival, and are diagnosed at a significantly younger age compared to NHW patients. AN patients differ from NHW patients in greater prevalence of non-cardia, diffuse subtype, and signet ring cell carcinomas. AN females were more likely to be diagnosed with later stage cancer, stage IV, compared to AN males. Diminished overall survival was observed among AN patients with increasing stage, O+ blood type, < 15 lymph nodes examined at resection, and no treatment. This study is the first report detailing the clinicopathologic features of gastric cancer in AN people with outcome data. CONCLUSION Our findings confirm the importance of early detection, treatment, and surgical resection for optimizing AN patient outcomes. Further research on early detection markers are warranted.
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Nasopharyngeal cancer in Alaska Native people: A cancer Health Disparity.
Journal of Clinical Oncology, 2018Co-Authors: Matthew J. Olnes, Erik Pihl, Mariah Minder, Julia Clerc Parrish, Peter Holck, Jim Tiesinga, Barbara Stillwater, Garrett Zimpelman, Sarah H. Nash, Holly A. MartinsonAbstract:1574Background: Cancer is a leading cause of death in Alaska Native (AN) people. Significant cancer Health disparities exist in both incidence and mortality between AN people and the US Whites. Nasopharyngeal cancer (NPC) is the leading cancer Disparity among AN people, with an incidence rate 17.3 times higher (2009-2013) and a mortality rate that is 21 times higher (1992-2011) than those in US whites. The etiologic basis for these disparities has not been identified. Methods: To better understand this Health Disparity, we created an Alaska Native NPC patient database derived from the Alaska Native Tumor Registry and Alaska Native Medical Center Tumor Registry to characterize all cases of NPC in AN people over the last forty years. We identified 186 cases of NPC in AN people from 1976 to 2016 by merging electronic data sets from the Alaska Native Medical Center Tumor Registry and the Alaska Native Tumor Registry, and analyzed, baseline demographics, clinical and pathologic features, patterns of care, and ...
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abstract 5284 gastric cancer in alaska native people a cancer Health Disparity
Cancer Research, 2017Co-Authors: Holly A. Martinson, Steven R Alberts, Matthew J. OlnesAbstract:Gastric cancer in the Alaska Native (AN) people occurs at a 3-fold higher incidence and 4-fold higher mortality rate compared to Non-Hispanic Whites (NHW), representing one of the largest cancer disparities in the AN population. We aimed to review the AN gastric cancer burden and identify clinicopathological factors that are associated with cancer outcomes. Patient information was collected from 132 AN gastric cancer patients diagnosed between 2006-2015 at the Alaska Native Medical Center. The Surveillance, Epidemiology and End Result database 18 was used to collect comparison United States NHW gastric cancer patient data. Compared to NHW patients, AN gastric cancer patients have a higher incidence rate, are significantly younger, 60 versus 69 years, and have a poorer 5-year overall survival rate of 10% compared to 22%. AN patients differ from NHW patients in gastric cancer anatomic location, subtype, and higher presence of signet ring cell carcinomas. Forty-one percent of AN patients were positive at the time of diagnosis for Helicobacter pylori, 77% had chronic gastritis, 30% had a family history of a first-degree relative with gastrointestinal cancers, and 82% were current or former tobacco users. Using univariate analysis, diminished overall survival was observed with anatomic site, increasing stage, no treatment, the number of lymph nodes examined during resection, blood type, and chronic gastritis. Multivariable analysis revealed stage and treatment type were independently associated with improved overall survival. AN gastric cancer cases vary in their clinical and epidemiologic features, relative to NHW. Citation Format: Holly Martinson, Steven Alberts, Matthew Olnes. Gastric cancer in Alaska Native people: A cancer Health Disparity [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 5284. doi:10.1158/1538-7445.AM2017-5284
Holly A. Martinson - One of the best experts on this subject based on the ideXlab platform.
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gastric cancer in alaska native people a cancer Health Disparity
World Journal of Gastroenterology, 2018Co-Authors: Holly A. Martinson, Steven R Alberts, Nancy J Shelby, Matthew J. OlnesAbstract:AIM To evaluate recent trends in gastric cancer incidence, response to treatment, and overall survival among Alaska Native (AN) people. METHODS A retrospective analysis of the Alaska Native Medical Center patient database was performed. Patient history, clinical, pathological, response to treatment and patient outcomes were collected from one-hundred and thirty-two AN gastric cancer patients. The Surveillance, Epidemiology and End Result database 18 was used to collect comparison United States non-Hispanic White (NHW) and AN gastric cancer patient data between 2006-2014. RESULTS AN gastric cancer patients have a higher incidence rate, a poorer overall survival, and are diagnosed at a significantly younger age compared to NHW patients. AN patients differ from NHW patients in greater prevalence of non-cardia, diffuse subtype, and signet ring cell carcinomas. AN females were more likely to be diagnosed with later stage cancer, stage IV, compared to AN males. Diminished overall survival was observed among AN patients with increasing stage, O+ blood type, < 15 lymph nodes examined at resection, and no treatment. This study is the first report detailing the clinicopathologic features of gastric cancer in AN people with outcome data. CONCLUSION Our findings confirm the importance of early detection, treatment, and surgical resection for optimizing AN patient outcomes. Further research on early detection markers are warranted.
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Nasopharyngeal cancer in Alaska Native people: A cancer Health Disparity.
Journal of Clinical Oncology, 2018Co-Authors: Matthew J. Olnes, Erik Pihl, Mariah Minder, Julia Clerc Parrish, Peter Holck, Jim Tiesinga, Barbara Stillwater, Garrett Zimpelman, Sarah H. Nash, Holly A. MartinsonAbstract:1574Background: Cancer is a leading cause of death in Alaska Native (AN) people. Significant cancer Health disparities exist in both incidence and mortality between AN people and the US Whites. Nasopharyngeal cancer (NPC) is the leading cancer Disparity among AN people, with an incidence rate 17.3 times higher (2009-2013) and a mortality rate that is 21 times higher (1992-2011) than those in US whites. The etiologic basis for these disparities has not been identified. Methods: To better understand this Health Disparity, we created an Alaska Native NPC patient database derived from the Alaska Native Tumor Registry and Alaska Native Medical Center Tumor Registry to characterize all cases of NPC in AN people over the last forty years. We identified 186 cases of NPC in AN people from 1976 to 2016 by merging electronic data sets from the Alaska Native Medical Center Tumor Registry and the Alaska Native Tumor Registry, and analyzed, baseline demographics, clinical and pathologic features, patterns of care, and ...
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abstract 5284 gastric cancer in alaska native people a cancer Health Disparity
Cancer Research, 2017Co-Authors: Holly A. Martinson, Steven R Alberts, Matthew J. OlnesAbstract:Gastric cancer in the Alaska Native (AN) people occurs at a 3-fold higher incidence and 4-fold higher mortality rate compared to Non-Hispanic Whites (NHW), representing one of the largest cancer disparities in the AN population. We aimed to review the AN gastric cancer burden and identify clinicopathological factors that are associated with cancer outcomes. Patient information was collected from 132 AN gastric cancer patients diagnosed between 2006-2015 at the Alaska Native Medical Center. The Surveillance, Epidemiology and End Result database 18 was used to collect comparison United States NHW gastric cancer patient data. Compared to NHW patients, AN gastric cancer patients have a higher incidence rate, are significantly younger, 60 versus 69 years, and have a poorer 5-year overall survival rate of 10% compared to 22%. AN patients differ from NHW patients in gastric cancer anatomic location, subtype, and higher presence of signet ring cell carcinomas. Forty-one percent of AN patients were positive at the time of diagnosis for Helicobacter pylori, 77% had chronic gastritis, 30% had a family history of a first-degree relative with gastrointestinal cancers, and 82% were current or former tobacco users. Using univariate analysis, diminished overall survival was observed with anatomic site, increasing stage, no treatment, the number of lymph nodes examined during resection, blood type, and chronic gastritis. Multivariable analysis revealed stage and treatment type were independently associated with improved overall survival. AN gastric cancer cases vary in their clinical and epidemiologic features, relative to NHW. Citation Format: Holly Martinson, Steven Alberts, Matthew Olnes. Gastric cancer in Alaska Native people: A cancer Health Disparity [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 5284. doi:10.1158/1538-7445.AM2017-5284
Wen Shen Isabella Chung - One of the best experts on this subject based on the ideXlab platform.
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a 10 year experience with universal Health insurance in taiwan measuring changes in Health and Health Disparity
Annals of Internal Medicine, 2008Co-Authors: Chi Pang Wen, Shan Pou Tsai, Wen Shen Isabella ChungAbstract:In 1995, Taiwan implemented national Health insurance. Wen and associates assessed its role in improving life expectancy and reducing Health disparities in Taiwan. Differences in life expectancy be...
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Reducing Health Disparity in Taiwan: quantifying the role of smoking.
Tobacco Control, 2005Co-Authors: T Y Cheng, Chi Pang Wen, Shan Pou Tsai, Wen Shen Isabella Chung, C C HsuAbstract:Objective: To assess the impact of smoking disparities on Health disparities, in terms of gap in life expectancy, in Taiwan cities and counties. Methods: Using the decomposition method of life expectancy, the contribution of each disease category to the life expectancy gap was quantitatively expressed as the number of years of life. The smoking attributable fraction (SAF) was calculated for each city and county based on their respective smoking prevalence and relative risk for each smoking related disease. The smoking attributable gap (SAG) in life expectancy between two sites is the sum of the difference in SAF between two sites for each smoking related disease multiplied by the number of years this disease contributed to the life expectancy gap. Results: Significant Health and smoking disparities were present among the 23 cities and counties in Taiwan. These Health disparities and smoking disparities were highly correlated (R2 = 0.3676). Generally, the Health gap increased with increasing smoking Disparity. The Disparity in smoking prevalence and intensity among cities and counties in Taiwan was responsible for up to 19% of the Health Disparity. The Health Disparity is also highly correlated (R2 = 0.3745) with SAG in life expectancy. Conclusions: Reducing smoking is important to Health, and reducing the smoking Disparity is also important for reducing the Health Disparity observed in Taiwan. The larger the Health Disparity is, the more important the smoking attributable Disparity could be. The reduction of smoking disparities could be a realistic and cost effective way toward reducing Health disparities.
Jessica P. Brown - One of the best experts on this subject based on the ideXlab platform.
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Lesbians and cancer: an overlooked Health Disparity
Cancer Causes & Control, 2008Co-Authors: Jessica P. Brown, J. Kathleen TracyAbstract:Objective To evaluate the breast, cervical, ovarian, lung, and colorectal cancer literatures using a novel application of the cancer disparities grid to identify disparities along domains of the cancer continuum focusing on lesbians as a minority population. Methods Computerized databases were searched for articles published from 1981 to present. Cumulative search results identified 51 articles related to lesbians and disparities, which were classified by domain. Results The majority of articles identified were related to breast and cervical cancer screening. Barriers to adequate screening for both cancers include personal factors, poor patient-provider communication, and Health care system factors. Tailored risk counseling has been successful in increasing lesbian’s mammography and Pap screening. Ovarian, lung, and colorectal cancer have been virtually unexplored in this population. An “Adjustment to Illness/Quality of Life” domain was added to capture literature on psychosocial aspects of cancer. Conclusions This review revealed a lack of research for specific cancers and for specific aspects of the cancer continuum. The limited number of studies identified focused on issues related to screening/prevention in cervical and breast cancers, with almost no attention to incidence, etiology, diagnosis, treatment, survival, morbidity, or mortality. We present implications for social and public Health policy, research, and prevention.
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lesbians and cancer an overlooked Health Disparity
Cancer Causes & Control, 2008Co-Authors: Jessica P. Brown, Kathleen J TracyAbstract:Objective To evaluate the breast, cervical, ovarian, lung, and colorectal cancer literatures using a novel application of the cancer disparities grid to identify disparities along domains of the cancer continuum focusing on lesbians as a minority population.
Chi Pang Wen - One of the best experts on this subject based on the ideXlab platform.
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a 10 year experience with universal Health insurance in taiwan measuring changes in Health and Health Disparity
Annals of Internal Medicine, 2008Co-Authors: Chi Pang Wen, Shan Pou Tsai, Wen Shen Isabella ChungAbstract:In 1995, Taiwan implemented national Health insurance. Wen and associates assessed its role in improving life expectancy and reducing Health disparities in Taiwan. Differences in life expectancy be...
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Reducing Health Disparity in Taiwan: quantifying the role of smoking.
Tobacco Control, 2005Co-Authors: T Y Cheng, Chi Pang Wen, Shan Pou Tsai, Wen Shen Isabella Chung, C C HsuAbstract:Objective: To assess the impact of smoking disparities on Health disparities, in terms of gap in life expectancy, in Taiwan cities and counties. Methods: Using the decomposition method of life expectancy, the contribution of each disease category to the life expectancy gap was quantitatively expressed as the number of years of life. The smoking attributable fraction (SAF) was calculated for each city and county based on their respective smoking prevalence and relative risk for each smoking related disease. The smoking attributable gap (SAG) in life expectancy between two sites is the sum of the difference in SAF between two sites for each smoking related disease multiplied by the number of years this disease contributed to the life expectancy gap. Results: Significant Health and smoking disparities were present among the 23 cities and counties in Taiwan. These Health disparities and smoking disparities were highly correlated (R2 = 0.3676). Generally, the Health gap increased with increasing smoking Disparity. The Disparity in smoking prevalence and intensity among cities and counties in Taiwan was responsible for up to 19% of the Health Disparity. The Health Disparity is also highly correlated (R2 = 0.3745) with SAG in life expectancy. Conclusions: Reducing smoking is important to Health, and reducing the smoking Disparity is also important for reducing the Health Disparity observed in Taiwan. The larger the Health Disparity is, the more important the smoking attributable Disparity could be. The reduction of smoking disparities could be a realistic and cost effective way toward reducing Health disparities.
