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Scott D Nash - One of the best experts on this subject based on the ideXlab platform.
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long term assessment of systemic inflammation and the cumulative incidence of age related Hearing Impairment in the epidemiology of Hearing loss study
Journals of Gerontology Series A-biological Sciences and Medical Sciences, 2014Co-Authors: Scott D Nash, Karen J Cruickshanks, Weihai Zhan, Michael Y Tsai, Ronald Klein, Rick Chappell, Javier F Nieto, Barbara E K Klein, Carla R Schubert, Dayna S DaltonAbstract:Background Although research has linked systemic inflammation to various diseases of aging, few studies have examined the potential role it may play in the development of age-related Hearing Impairment. Methods Among 1,073 participants free of Hearing Impairment (pure-tone average 0.5, 1, 2, 4kHz ≤ 25 dB HL) in the population-based Epidemiology of Hearing Loss Study (1998-2000), serum C-reactive protein, and interleukin-6 were measured at three time points (1988-1990, 1998-2000, and 2009-2010), and tumor necrosis factor-α was measured at one time point (1998-2000), whereas Hearing Impairment was measured again in 2003-2005 and 2009-2010 to determine the 10-year cumulative incidence. Results Inflammatory marker levels from a single time point (1998-2000) were not associated with an increased risk of developing Hearing Impairment. Associations between long-term serum C-reactive protein levels and incident Hearing Impairment differed by age (p = .031). Participants less than 60 years with consistently high (>3 mg/L) or increasing levels of serum C-reactive protein over 10 years were nearly two times (hazard ratio: 1.96, 95% confidence interval: 1.19, 3.23) as likely to develop Hearing Impairment over the subsequent 10-year period, an association not seen in participants more than or equal to 60 years. A statistically significant association (p-trend = .041) was also observed between number of markers in the highest group at baseline and incident Hearing Impairment in this younger age group. Conclusions Associations between long-term serum C-reactive protein levels and incident Hearing Impairment were observed in the cohort as a whole, but differed significantly by age group, with statistically significant associations observed in adults less than 60 years, participants moving through the peak risk period for Hearing Impairment over the course of the study.
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education occupation noise exposure history and the 10 yr cumulative incidence of Hearing Impairment in older adults
Hearing Research, 2010Co-Authors: Karen J Cruickshanks, Ronald Klein, Rick Chappell, Barbara E K Klein, Dayna S Dalton, David M Nondahl, Ted S Tweed, Terry L Wiley, Scott D NashAbstract:The purpose of this study was to determine the 10-yr cumulative incidence of Hearing Impairment and associations of education, occupation and noise exposure history with the incidence of Hearing Impairment in a population-based cohort study of 3753 adults ages 48-92 yr at the baseline examinations during 1993-1995 in Beaver Dam, WI. Hearing thresholds were measured at baseline, 2.5 yr-, 5 yr-, and 10-yr follow-up examinations. Hearing Impairment was defined as a pure-tone average (PTA)>25 dB HL at 500, 1000, 2000, and 4000 Hz. Demographic characteristics and occupational histories were obtained by questionnaire. The 10-yr cumulative incidence of Hearing Impairment was 37.2%. Age (5 yr; Hazard Ratio (HR)=1.81), sex (M vs W; HR=2.29), occupation based on longest held job (production/operations/farming vs others; HR=1.34), marital status (unmarried vs married; HR=1.29) and education (<16 vs 16+yr; HR=1.40) were associated with the 10 yr incidence. History of noisy jobs was not associated with the 10-yr incidence of Hearing Impairment. The risk of Hearing Impairment was high, with women experiencing a slightly later onset. Markers of socioeconomic status were associated with Hearing Impairment, suggesting that Hearing Impairment in older adults may be associated with modifiable lifestyle and environmental factors, and therefore, at least partially preventable.
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education occupation noise exposure history and the 10 yr cumulative incidence of Hearing Impairment in older adults
Hearing Research, 2010Co-Authors: Karen J Cruickshanks, Ronald Klein, Rick Chappell, Barbara E K Klein, Dayna S Dalton, David M Nondahl, Ted S Tweed, Terry L Wiley, Scott D NashAbstract:Abstract The purpose of this study was to determine the 10-yr cumulative incidence of Hearing Impairment and associations of education, occupation and noise exposure history with the incidence of Hearing Impairment in a population-based cohort study of 3753 adults ages 48–92 yr at the baseline examinations during 1993–1995 in Beaver Dam, WI. Hearing thresholds were measured at baseline, 2.5 yr-, 5 yr-, and 10-yr follow-up examinations. Hearing Impairment was defined as a pure-tone average (PTA) > 25 dB HL at 500, 1000, 2000, and 4000 Hz. Demographic characteristics and occupational histories were obtained by questionnaire. The 10-yr cumulative incidence of Hearing Impairment was 37.2%. Age (5 yr; Hazard Ratio (HR) = 1.81), sex (M vs W; HR = 2.29), occupation based on longest held job (production/operations/farming vs others; HR = 1.34), marital status (unmarried vs married; HR = 1.29) and education (
Karen J Cruickshanks - One of the best experts on this subject based on the ideXlab platform.
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Hearing Impairment prevalence and associated risk factors in the hispanic community health study study of latinos
Archives of Otolaryngology-head & Neck Surgery, 2015Co-Authors: Karen J Cruickshanks, Sumitrajit Dhar, Elizabeth A Dinces, Robert C Fifer, Franklyn Gonzalez, Gerardo Heiss, Howard J Hoffman, Marilyn Newhoff, Laura Tocci, Peter TorreAbstract:Importance Hearing Impairment is common in adults, but few studies have addressed it in the US Hispanic/Latino population. Objective To determine the prevalence of Hearing Impairment among US Hispanic/Latino adults of diverse backgrounds and determine associations with potential risk factors. Design, Setting, and Participants The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a population-based sample of Hispanics/Latinos in four US communities (Bronx, New York; Chicago, Illinois; Miami, Florida; and San Diego, California). Examinations were conducted from 2008 through 2011. The HCHS/SOL examined 16 415 self-identified Hispanic/Latino persons aged 18 to 74 years recruited from randomly selected households using a stratified 2-stage area probability sample design based on census block groups and households within block groups. Main Outcomes and Measures Hearing thresholds were measured by pure-tone audiometry. Hearing Impairment was defined as a pure-tone average (PTA) of thresholds at 0.5, 1, 2, and 4 kHz greater than 25 dB Hearing level. Bilateral Hearing Impairment required a PTA greater than 25 dB Hearing level in both ears. Multivariable analyses included adjustments for sociodemographic and lifestyle variables, body mass index, and medical conditions. Results The prevalence of Hearing Impairment was 15.06% (SE, 0.44%) overall, and 8.24% (SE, 0.33%) had bilateral Hearing Impairment. The prevalence of Hearing Impairment was higher among people 45 years and older, ranging by Hispanic/Latino background from 29.35% to 41.20% among men and 17.89% to 32.11% among women. The multivariable-adjusted odds of Hearing Impairment was greater for participants of Puerto Rican background compared with Mexican background (odds ratio [OR], 1.57 [95% CI, 1.10-2.25]). The odds of Hearing Impairment were lower with more education (OR, 0.71 [95% CI, 0.59-0.86] for at least high school) and higher income (OR, 0.58 [95% CI, 0.36-0.92] for >$75 000 vs ≤$10 000). Noise exposure (OR, 1.35 [95% CI, 1.07-1.70]), diabetes (OR, 1.57 [95% CI, 1.27-1.94]), and prediabetes (OR, 1.37 [95% CI, 1.12-1.67]) were associated with Hearing Impairment. Conclusions and Relevance Hearing Impairment is a common problem for older Hispanics/Latinos in these communities and is associated with socioeconomic factors, noise exposure, and abnormal glucose metabolism. Longitudinal studies are needed to determine whether these factors are involved in the etiology of Hearing Impairment and to identify ways to prevent or delay age-related changes in Hearing.
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long term assessment of systemic inflammation and the cumulative incidence of age related Hearing Impairment in the epidemiology of Hearing loss study
Journals of Gerontology Series A-biological Sciences and Medical Sciences, 2014Co-Authors: Scott D Nash, Karen J Cruickshanks, Weihai Zhan, Michael Y Tsai, Ronald Klein, Rick Chappell, Javier F Nieto, Barbara E K Klein, Carla R Schubert, Dayna S DaltonAbstract:Background Although research has linked systemic inflammation to various diseases of aging, few studies have examined the potential role it may play in the development of age-related Hearing Impairment. Methods Among 1,073 participants free of Hearing Impairment (pure-tone average 0.5, 1, 2, 4kHz ≤ 25 dB HL) in the population-based Epidemiology of Hearing Loss Study (1998-2000), serum C-reactive protein, and interleukin-6 were measured at three time points (1988-1990, 1998-2000, and 2009-2010), and tumor necrosis factor-α was measured at one time point (1998-2000), whereas Hearing Impairment was measured again in 2003-2005 and 2009-2010 to determine the 10-year cumulative incidence. Results Inflammatory marker levels from a single time point (1998-2000) were not associated with an increased risk of developing Hearing Impairment. Associations between long-term serum C-reactive protein levels and incident Hearing Impairment differed by age (p = .031). Participants less than 60 years with consistently high (>3 mg/L) or increasing levels of serum C-reactive protein over 10 years were nearly two times (hazard ratio: 1.96, 95% confidence interval: 1.19, 3.23) as likely to develop Hearing Impairment over the subsequent 10-year period, an association not seen in participants more than or equal to 60 years. A statistically significant association (p-trend = .041) was also observed between number of markers in the highest group at baseline and incident Hearing Impairment in this younger age group. Conclusions Associations between long-term serum C-reactive protein levels and incident Hearing Impairment were observed in the cohort as a whole, but differed significantly by age group, with statistically significant associations observed in adults less than 60 years, participants moving through the peak risk period for Hearing Impairment over the course of the study.
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education occupation noise exposure history and the 10 yr cumulative incidence of Hearing Impairment in older adults
Hearing Research, 2010Co-Authors: Karen J Cruickshanks, Ronald Klein, Rick Chappell, Barbara E K Klein, Dayna S Dalton, David M Nondahl, Ted S Tweed, Terry L Wiley, Scott D NashAbstract:The purpose of this study was to determine the 10-yr cumulative incidence of Hearing Impairment and associations of education, occupation and noise exposure history with the incidence of Hearing Impairment in a population-based cohort study of 3753 adults ages 48-92 yr at the baseline examinations during 1993-1995 in Beaver Dam, WI. Hearing thresholds were measured at baseline, 2.5 yr-, 5 yr-, and 10-yr follow-up examinations. Hearing Impairment was defined as a pure-tone average (PTA)>25 dB HL at 500, 1000, 2000, and 4000 Hz. Demographic characteristics and occupational histories were obtained by questionnaire. The 10-yr cumulative incidence of Hearing Impairment was 37.2%. Age (5 yr; Hazard Ratio (HR)=1.81), sex (M vs W; HR=2.29), occupation based on longest held job (production/operations/farming vs others; HR=1.34), marital status (unmarried vs married; HR=1.29) and education (<16 vs 16+yr; HR=1.40) were associated with the 10 yr incidence. History of noisy jobs was not associated with the 10-yr incidence of Hearing Impairment. The risk of Hearing Impairment was high, with women experiencing a slightly later onset. Markers of socioeconomic status were associated with Hearing Impairment, suggesting that Hearing Impairment in older adults may be associated with modifiable lifestyle and environmental factors, and therefore, at least partially preventable.
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education occupation noise exposure history and the 10 yr cumulative incidence of Hearing Impairment in older adults
Hearing Research, 2010Co-Authors: Karen J Cruickshanks, Ronald Klein, Rick Chappell, Barbara E K Klein, Dayna S Dalton, David M Nondahl, Ted S Tweed, Terry L Wiley, Scott D NashAbstract:Abstract The purpose of this study was to determine the 10-yr cumulative incidence of Hearing Impairment and associations of education, occupation and noise exposure history with the incidence of Hearing Impairment in a population-based cohort study of 3753 adults ages 48–92 yr at the baseline examinations during 1993–1995 in Beaver Dam, WI. Hearing thresholds were measured at baseline, 2.5 yr-, 5 yr-, and 10-yr follow-up examinations. Hearing Impairment was defined as a pure-tone average (PTA) > 25 dB HL at 500, 1000, 2000, and 4000 Hz. Demographic characteristics and occupational histories were obtained by questionnaire. The 10-yr cumulative incidence of Hearing Impairment was 37.2%. Age (5 yr; Hazard Ratio (HR) = 1.81), sex (M vs W; HR = 2.29), occupation based on longest held job (production/operations/farming vs others; HR = 1.34), marital status (unmarried vs married; HR = 1.29) and education (
Dayna S Dalton - One of the best experts on this subject based on the ideXlab platform.
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long term assessment of systemic inflammation and the cumulative incidence of age related Hearing Impairment in the epidemiology of Hearing loss study
Journals of Gerontology Series A-biological Sciences and Medical Sciences, 2014Co-Authors: Scott D Nash, Karen J Cruickshanks, Weihai Zhan, Michael Y Tsai, Ronald Klein, Rick Chappell, Javier F Nieto, Barbara E K Klein, Carla R Schubert, Dayna S DaltonAbstract:Background Although research has linked systemic inflammation to various diseases of aging, few studies have examined the potential role it may play in the development of age-related Hearing Impairment. Methods Among 1,073 participants free of Hearing Impairment (pure-tone average 0.5, 1, 2, 4kHz ≤ 25 dB HL) in the population-based Epidemiology of Hearing Loss Study (1998-2000), serum C-reactive protein, and interleukin-6 were measured at three time points (1988-1990, 1998-2000, and 2009-2010), and tumor necrosis factor-α was measured at one time point (1998-2000), whereas Hearing Impairment was measured again in 2003-2005 and 2009-2010 to determine the 10-year cumulative incidence. Results Inflammatory marker levels from a single time point (1998-2000) were not associated with an increased risk of developing Hearing Impairment. Associations between long-term serum C-reactive protein levels and incident Hearing Impairment differed by age (p = .031). Participants less than 60 years with consistently high (>3 mg/L) or increasing levels of serum C-reactive protein over 10 years were nearly two times (hazard ratio: 1.96, 95% confidence interval: 1.19, 3.23) as likely to develop Hearing Impairment over the subsequent 10-year period, an association not seen in participants more than or equal to 60 years. A statistically significant association (p-trend = .041) was also observed between number of markers in the highest group at baseline and incident Hearing Impairment in this younger age group. Conclusions Associations between long-term serum C-reactive protein levels and incident Hearing Impairment were observed in the cohort as a whole, but differed significantly by age group, with statistically significant associations observed in adults less than 60 years, participants moving through the peak risk period for Hearing Impairment over the course of the study.
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education occupation noise exposure history and the 10 yr cumulative incidence of Hearing Impairment in older adults
Hearing Research, 2010Co-Authors: Karen J Cruickshanks, Ronald Klein, Rick Chappell, Barbara E K Klein, Dayna S Dalton, David M Nondahl, Ted S Tweed, Terry L Wiley, Scott D NashAbstract:The purpose of this study was to determine the 10-yr cumulative incidence of Hearing Impairment and associations of education, occupation and noise exposure history with the incidence of Hearing Impairment in a population-based cohort study of 3753 adults ages 48-92 yr at the baseline examinations during 1993-1995 in Beaver Dam, WI. Hearing thresholds were measured at baseline, 2.5 yr-, 5 yr-, and 10-yr follow-up examinations. Hearing Impairment was defined as a pure-tone average (PTA)>25 dB HL at 500, 1000, 2000, and 4000 Hz. Demographic characteristics and occupational histories were obtained by questionnaire. The 10-yr cumulative incidence of Hearing Impairment was 37.2%. Age (5 yr; Hazard Ratio (HR)=1.81), sex (M vs W; HR=2.29), occupation based on longest held job (production/operations/farming vs others; HR=1.34), marital status (unmarried vs married; HR=1.29) and education (<16 vs 16+yr; HR=1.40) were associated with the 10 yr incidence. History of noisy jobs was not associated with the 10-yr incidence of Hearing Impairment. The risk of Hearing Impairment was high, with women experiencing a slightly later onset. Markers of socioeconomic status were associated with Hearing Impairment, suggesting that Hearing Impairment in older adults may be associated with modifiable lifestyle and environmental factors, and therefore, at least partially preventable.
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education occupation noise exposure history and the 10 yr cumulative incidence of Hearing Impairment in older adults
Hearing Research, 2010Co-Authors: Karen J Cruickshanks, Ronald Klein, Rick Chappell, Barbara E K Klein, Dayna S Dalton, David M Nondahl, Ted S Tweed, Terry L Wiley, Scott D NashAbstract:Abstract The purpose of this study was to determine the 10-yr cumulative incidence of Hearing Impairment and associations of education, occupation and noise exposure history with the incidence of Hearing Impairment in a population-based cohort study of 3753 adults ages 48–92 yr at the baseline examinations during 1993–1995 in Beaver Dam, WI. Hearing thresholds were measured at baseline, 2.5 yr-, 5 yr-, and 10-yr follow-up examinations. Hearing Impairment was defined as a pure-tone average (PTA) > 25 dB HL at 500, 1000, 2000, and 4000 Hz. Demographic characteristics and occupational histories were obtained by questionnaire. The 10-yr cumulative incidence of Hearing Impairment was 37.2%. Age (5 yr; Hazard Ratio (HR) = 1.81), sex (M vs W; HR = 2.29), occupation based on longest held job (production/operations/farming vs others; HR = 1.34), marital status (unmarried vs married; HR = 1.29) and education (
Jacob Kuint - One of the best experts on this subject based on the ideXlab platform.
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PRE-AURICULAR SKIN TAGS AND EAR PITS ARE ASSOCIATED WITH PERMANENT Hearing Impairment IN NEWBORN INFANTS
Archives of Disease in Childhood, 2008Co-Authors: D Ari-evenroth, Minka Hildesheimer, Dvora Goidel, Brian Reichman, Ayala Maayan-metzger, S Bradenstein, Jacob KuintAbstract:Objective To evaluate the incidence of Hearing Impairment in infants with or without preauricular skin tags or ear pits. Patients and Methods During 7.5 years, 68 484 infants were screened, of whom 637 (0.93%) had preauricular skin tags or ear pits. The population was divided into three groups: (1) a low-risk group for Hearing Impairment (n = 65 051) included 587 infants with isolated preauricular skin tags or pits; (2) a high-risk group (n = 3406) included 39 infants with preauricular skin tags or pits and (3) a very high-risk group with major auricular deformities (n = 27) included 11 infants with preauricular skin tags or pits. The latter group was excluded from further analysis. Results Five infants out of 626 infants (8/1000) with preauricular skin tags or ear pits had permanent Hearing Impairment compared with 100 out of 67 831 (1.5/1000) without skin tags or ear pits (p Conclusions Infants with preauricular skin tags or pits are at excess risk for the presence of permanent conductive or sensorineural Hearing Impairment.
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Preauricular skin tags and ear pits are associated with permanent Hearing Impairment in newborns.
Pediatrics, 2008Co-Authors: Daphne Ari-even Roth, Minka Hildesheimer, Sarit Bardenstein, Dvora Goidel, Brian Reichman, Ayala Maayan-metzger, Jacob KuintAbstract:OBJECTIVES. Our goals were to (1) study the prevalence of Hearing Impairment in a large cohort of infants with preauricular skin tags or ear pits and compare it with that among all other newborns participating in our universal newborn Hearing screening program during the same period and (2) evaluate the effectiveness of transient evoked otoacoustic emissions as a Hearing-screening tool in this population. PATIENTS AND METHODS. During the study period of 7.5 years, 68484 infants were screened for Hearing Impairment, of whom 637 (0.93%) had preauricular skin tags and/or ear pits. The population was divided into 3 groups: (1) a low-risk group for Hearing Impairment; (2) a high-risk group for Hearing Impairment; and (3) a very high-risk group for Hearing Impairment. The screening results and audiological follow-up for these infants were examined retrospectively. RESULTS. A significantly higher prevalence of permanent Hearing Impairment was found among infants with preauricular skin tags or ear pits (8 of 1000), compared with infants without tags or pits (1.5 of 1000). In the low-risk group, the prevalence was 3.4 of 1000, compared with 0.5 of 1000 in infants with and without preauricular tags or pits, respectively. In the high-risk group, the prevalence was 77 of 1000, compared with 20 of 1000 in infants with and without preauricular tags or pits, respectively. The odds ratio for Hearing Impairment associated with preauricular skin tags and/or ear pits after adjusting for level of risk group was 4.9. All infants diagnosed with permanent Hearing Impairment, with the exception of 1 with late-onset Impairment, were detected by in-hospital transient-evoked otoacoustic emissions screening. CONCLUSIONS. Infants with preauricular skin tags or ear pits are at increased risk for permanent Hearing Impairment. Transient-evoked otoacoustic emissions were found to be an effective Hearing-screening tool in this population.
Ronald Klein - One of the best experts on this subject based on the ideXlab platform.
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long term assessment of systemic inflammation and the cumulative incidence of age related Hearing Impairment in the epidemiology of Hearing loss study
Journals of Gerontology Series A-biological Sciences and Medical Sciences, 2014Co-Authors: Scott D Nash, Karen J Cruickshanks, Weihai Zhan, Michael Y Tsai, Ronald Klein, Rick Chappell, Javier F Nieto, Barbara E K Klein, Carla R Schubert, Dayna S DaltonAbstract:Background Although research has linked systemic inflammation to various diseases of aging, few studies have examined the potential role it may play in the development of age-related Hearing Impairment. Methods Among 1,073 participants free of Hearing Impairment (pure-tone average 0.5, 1, 2, 4kHz ≤ 25 dB HL) in the population-based Epidemiology of Hearing Loss Study (1998-2000), serum C-reactive protein, and interleukin-6 were measured at three time points (1988-1990, 1998-2000, and 2009-2010), and tumor necrosis factor-α was measured at one time point (1998-2000), whereas Hearing Impairment was measured again in 2003-2005 and 2009-2010 to determine the 10-year cumulative incidence. Results Inflammatory marker levels from a single time point (1998-2000) were not associated with an increased risk of developing Hearing Impairment. Associations between long-term serum C-reactive protein levels and incident Hearing Impairment differed by age (p = .031). Participants less than 60 years with consistently high (>3 mg/L) or increasing levels of serum C-reactive protein over 10 years were nearly two times (hazard ratio: 1.96, 95% confidence interval: 1.19, 3.23) as likely to develop Hearing Impairment over the subsequent 10-year period, an association not seen in participants more than or equal to 60 years. A statistically significant association (p-trend = .041) was also observed between number of markers in the highest group at baseline and incident Hearing Impairment in this younger age group. Conclusions Associations between long-term serum C-reactive protein levels and incident Hearing Impairment were observed in the cohort as a whole, but differed significantly by age group, with statistically significant associations observed in adults less than 60 years, participants moving through the peak risk period for Hearing Impairment over the course of the study.
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education occupation noise exposure history and the 10 yr cumulative incidence of Hearing Impairment in older adults
Hearing Research, 2010Co-Authors: Karen J Cruickshanks, Ronald Klein, Rick Chappell, Barbara E K Klein, Dayna S Dalton, David M Nondahl, Ted S Tweed, Terry L Wiley, Scott D NashAbstract:The purpose of this study was to determine the 10-yr cumulative incidence of Hearing Impairment and associations of education, occupation and noise exposure history with the incidence of Hearing Impairment in a population-based cohort study of 3753 adults ages 48-92 yr at the baseline examinations during 1993-1995 in Beaver Dam, WI. Hearing thresholds were measured at baseline, 2.5 yr-, 5 yr-, and 10-yr follow-up examinations. Hearing Impairment was defined as a pure-tone average (PTA)>25 dB HL at 500, 1000, 2000, and 4000 Hz. Demographic characteristics and occupational histories were obtained by questionnaire. The 10-yr cumulative incidence of Hearing Impairment was 37.2%. Age (5 yr; Hazard Ratio (HR)=1.81), sex (M vs W; HR=2.29), occupation based on longest held job (production/operations/farming vs others; HR=1.34), marital status (unmarried vs married; HR=1.29) and education (<16 vs 16+yr; HR=1.40) were associated with the 10 yr incidence. History of noisy jobs was not associated with the 10-yr incidence of Hearing Impairment. The risk of Hearing Impairment was high, with women experiencing a slightly later onset. Markers of socioeconomic status were associated with Hearing Impairment, suggesting that Hearing Impairment in older adults may be associated with modifiable lifestyle and environmental factors, and therefore, at least partially preventable.
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education occupation noise exposure history and the 10 yr cumulative incidence of Hearing Impairment in older adults
Hearing Research, 2010Co-Authors: Karen J Cruickshanks, Ronald Klein, Rick Chappell, Barbara E K Klein, Dayna S Dalton, David M Nondahl, Ted S Tweed, Terry L Wiley, Scott D NashAbstract:Abstract The purpose of this study was to determine the 10-yr cumulative incidence of Hearing Impairment and associations of education, occupation and noise exposure history with the incidence of Hearing Impairment in a population-based cohort study of 3753 adults ages 48–92 yr at the baseline examinations during 1993–1995 in Beaver Dam, WI. Hearing thresholds were measured at baseline, 2.5 yr-, 5 yr-, and 10-yr follow-up examinations. Hearing Impairment was defined as a pure-tone average (PTA) > 25 dB HL at 500, 1000, 2000, and 4000 Hz. Demographic characteristics and occupational histories were obtained by questionnaire. The 10-yr cumulative incidence of Hearing Impairment was 37.2%. Age (5 yr; Hazard Ratio (HR) = 1.81), sex (M vs W; HR = 2.29), occupation based on longest held job (production/operations/farming vs others; HR = 1.34), marital status (unmarried vs married; HR = 1.29) and education (
