The Experts below are selected from a list of 7908 Experts worldwide ranked by ideXlab platform
Li-na Guan - One of the best experts on this subject based on the ideXlab platform.
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Assessment of the difference of myocardium strain between myocadial infarction and ventricular Aneurysm by two-dimensional speckle-tracking imaging in rabbits
Chinese Journal of Ultrasonography, 2012Co-Authors: Hong Zhai, Guliqiman·huojiaabudula, Li-na GuanAbstract:Objective To evaluate the difference of myocardium strain between myocadial infarction and ventricular Aneurysm (VA) by two-dimensional speckle-tracking imaging in rabbits.Methods 26 healthy New Zealand white rabbits were enrolled in this study,6 were put into the control group and 20 in the experimental group.models of myocardial infarction concomitant with VA were prepared by the ligation of the middle segment of left anterior descending artery and left circumflex artery.At 4 weeks after the procedure,according to the pathological inspect and echocardiography for whether VA formed,the experimental animals were divided into the VA group and the myocadial infarction group.Echocardiography was performed to measure the LV cavity size and cardiac function.Radial strain rate (SrR) and circumferential strain rate(SrC) indexes were measured by 2D-STI software for each animal at the level of apex in left ventricular short-axis view,and then calculated the strain rate decrease percentage in each segment.Results 1)Compared with the control group,SrR-S,SrR-E,SrR A,SrC-S,SrC-E,SrC-A in all segments were reduced significantly in the VA group and the myocadial infarction group (P ＜ 0.05),the VA group was the most significant.2)Compared with the myocadial infarction group,the strain rate decrease percentage of SrR-S,SrR-E,SrR-A,SrC-S,SrC-E,SrC-A in all segment had significant in the VA group.Comparison between the each section,the strain rate decrease percentage of SrR-Santerior wall,SrR-Sateral wall,SrC-Santerior wall,SrC-Slateral wall were the most significant.3)There were the tighter relationship between the strain rate decrease percentage of SrR-Santerior wall,SrC-Santerior wall,SrR-Slateral wall,SrC-Slateral wall and left ventricular ejection fraction (r =0.82,0.72,0.75,0.71,repectively,all P ＜ 0.05).4) The ROC curve analysis showed that when the strain rate decrease percentage was 60％ as the critical point,the strain rate decrease percentage of SrC-Santerior wall,SrC-Slateral wall,SrR-Santerior wall,SrR-Slateral wall had a sensitivity of 83.30 ％,84.40％,83.30％,67.70％％ and a specificity was 73.60％,78.20％％,69.70％,83.30％ for prognosis ventricular Aneurysm,repectively.Conclusions After ventricular Aneurysm formation,anterior and lateral wall myocardial strain were give priority to the myocardial mechanics reconstruction,thus systolic myocardial strain rate decrease percentage can be important indicator of infarction myocardial developing into ventricular Aneurysm. Key words: Echocardiography; Heart Aneurysm; Myocardial infarction; Ventricular function, left; Speckle-tracking imaging
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Assessment of left ventricular twist in rabbits with ventricular Aneurysm formed by two-dimensional speckle tracking echocardiography
Chinese Journal of Ultrasonography, 2012Co-Authors: Xue Yan, Li-na Guan, Hong Zhai, Yu-cheng ZhouAbstract:Objective To evaluate the influence on left ventricular(LV) twist,and the relationship between LV twist and function in the rabbits with ventricular Aneurysm formed after myocardial infarction by two-dimensional ultrasound speckle tracking imaging.Methods Twenty-six healthy rabbits were divided into two groups,six as control group,twenty as experimental group.The model of myocardial infarction and ventricular Aneurysm were established by ligaturing left anterior descending coronary artery and left circumflex artery.After four weeks,according to the pathological examination of whether ventricular Aneurysm formed or not,the experimental group was divided into myocardial infarct group and ventricular Aneurysm group.Echocardiography was performed to measure rotations (at the levels of mitral annulus and apex in LV short-axis view),LV twist,left ventricular cavity size and function.Results Compared with the myocardial infarct group,LV end-diastolic diameter(LVEDD) and LV end-diastolic volume(LVEDV) were larger in the ventricular Aneurysm group,but LV ejection fraction (LVEF),LV fractional shortening (LVFS),apical rotation and LV twist were lower in the ventricular Aneurysm group than the myocardial infarct group.Both apical rotation and LV twist had shown a great correlation with LVEF.The conclusion was also shown in the ROC curve that sensitivity and specificity of diagnosis cardiac dysfunction were 76.9％ and 80.0％ respectively when the apical rotation was 1.21°.Conclusions There was a closely relationship between the change of apical rotation and the LV systolic function.When the apical rotation dropped to 1.21°,an apparent decline of LV systolic function was implied. Key words: Echocardiography; Heart Aneurysm; Ventricular function,left; Rotation; Speckle tracking imaging
Xin Chen - One of the best experts on this subject based on the ideXlab platform.
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Clinical analysis of surgical treatment of post-infarction left ventricular Aneurysm: a series of 254 patients
Zhonghua wai ke za zhi [Chinese journal of surgery], 2020Co-Authors: Ying-shuo Jiang, Xin Chen, Zhibing Qiu, Liming Wang, Jun-jie ShaoAbstract:Objective To examine the efficacy of two surgical procedures on post-infarction left ventricular Aneurysm. Methods The clinic data of 254 patients with post-infarction left ventricular Aneurysm, who underwent surgical ventricular reconstruction between January 1997 and December 2019 in Department of Cardiovascular Surgery, Nanjing Hospital Affiliated to Nanjing Medical University was analyzed retrospectively. There were 183 males and 71 females aged from 31 to 81 years, with a median age of 64.6 years. Based on the size of the ventricular Aneurysm, there were 73 patient received linear reconstruction (linear group) and 181 patients received endoventricular patch plasty technique (patch plasty group). Ejection fraction, left ventricular systolic and end diastolic volume and left ventricular systolic and end diastolic volume index were recorded preoperatively, 2- week, 3- month, 1- year and 5- year after operation. The survival curves were plotted with Kaplan-Meier method and the survival rates were compared by Log-rank test. Results All patients underwent surgery with a mean cardiopulmonay bypass duration of (92±32) minutes (44 to 196 minutes) and aortic cross clamp duration of (67±22) minutes (33 to 152 minutes). There were 9 perioperative deaths with a mortality rate of 3.5%. Angina pectoris of other cases are relief and Heart function improved greatly. Five years after operation, the percentage of cardiac function (New Yord Heart Association) class Ⅲ to Ⅳ patients decreased from 96.1%(244/254) to 9.9%(16/161). There was no significant difference in survival rate between linear group and patch plasty group at 1-, 3-, 5-yearspostoperatively (96%, 91%, 77% vs. 96%, 90%, 79%, P=0.562). Ejection fraction increased from (39±10)% (range: 22% to 50%) preoperatively to (46±6)% (range: 39% to 54%) 1-year postoperatively in the linear group, while increased from (38±13)% (range: 26% to 51%) preoperatively to (50±6)% (range: 39% to 55%) in the patch plasty group. Conclusions Left ventricular reconstruction is quite effective for patients with post-infarction left ventricular Aneurysm. The choice of operative approaches is determined by the size and range of ventricular Aneurysm. Both linear reconstruction and endoventricular patch plasty technique can got similarly surgical outcomes with near and late curative effect. Key words: Myocardial infarction; Heart Aneurysm; Cardiac surgical procedures
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Surgical treatment of post-infarction left ventricular Aneurysm: clinical analysis
Zhonghua yi xue za zhi, 2010Co-Authors: Xin Chen, Zhibing Qiu, Ying-shuo Jiang, Liming Wang, Hong-wei Shi, Xu-jun Chen, Fuhua Huang, Liqiong XiaoAbstract:Objective To explore the clinical experiences, efficacies and postoperative left ventricular remodeling changes of surgical ventricular reconstruction in the treatment of post-infarction left ventricular Aneurysm. Methods The investigators reviewed retrospectively the clinical data, operative approaches and follow-up outcomes of consecutive 194 patients with post-infarction left ventricular Aneurysm,who underwent surgical ventricular reconstruction between January 1997 and December 2009. There were 54cases in the linear group and 137 cases in the endoventricular patch plasty group. The changes of ventricular remodeling were measured by peri-operative and follow-up echocardiography. Results All patients underwent surgery with a mean cardiopulmonay bypass duration of ( 103 ± 35 ) min and aortic cross clamp duration of (62 ±26)min. There were 8 per-operative deaths with a mortality rate of 2.2%. Angina pectoris of other cases disappeared and Heart function greatly improved. After operation, the ventricular remodeling results showed that in the linear group, there was not significant difference in the changes of ventricular remodeling of post-op 2 weeks, 6 months, 1 year and 5 years versus pre-operation. However, in the endoventricular patch group, the changes of ventricular remodeling of post-op 2 weeks and follow-up 6months versus pre-operation were significantly reduced( P ＜0.05). End-systolic volume (LNESV) reduced from ( 129 ± 27 ) ml to ( 65 ± 8 ) ml and end-systolic volume index ( LVESVI ) decreased from ( 104 ± 14 )ml/m2 to (44 ± 6) ml/m2 and the subgroup of LVEF ＜ 35% was the most significant in the changes of LVESV and LVESVI. But LVEF improved significantly at post-operation and follow-up (from preoperation 42% ± 11% to 52% ± 7% during follow-up). Conclusions For patients with infarction left ventricular Aneurysm, left ventricular reconstruction is quite effective. The choice of operative approaches is determined ty the size and range of ventricular Aneurysm. Both string suture and endoventricular patch plasty technique can yield similarly satisfactory surgical outcomes. After operation, ventricular volume significantly decreases and cardiac function greatly improves. Key words: Myocardial infarction; Heart Aneurysm; Coronary artery bypass; Left ventricular reconstruction
Ying-shuo Jiang - One of the best experts on this subject based on the ideXlab platform.
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Clinical analysis of surgical treatment of post-infarction left ventricular Aneurysm: a series of 254 patients
Zhonghua wai ke za zhi [Chinese journal of surgery], 2020Co-Authors: Ying-shuo Jiang, Xin Chen, Zhibing Qiu, Liming Wang, Jun-jie ShaoAbstract:Objective To examine the efficacy of two surgical procedures on post-infarction left ventricular Aneurysm. Methods The clinic data of 254 patients with post-infarction left ventricular Aneurysm, who underwent surgical ventricular reconstruction between January 1997 and December 2019 in Department of Cardiovascular Surgery, Nanjing Hospital Affiliated to Nanjing Medical University was analyzed retrospectively. There were 183 males and 71 females aged from 31 to 81 years, with a median age of 64.6 years. Based on the size of the ventricular Aneurysm, there were 73 patient received linear reconstruction (linear group) and 181 patients received endoventricular patch plasty technique (patch plasty group). Ejection fraction, left ventricular systolic and end diastolic volume and left ventricular systolic and end diastolic volume index were recorded preoperatively, 2- week, 3- month, 1- year and 5- year after operation. The survival curves were plotted with Kaplan-Meier method and the survival rates were compared by Log-rank test. Results All patients underwent surgery with a mean cardiopulmonay bypass duration of (92±32) minutes (44 to 196 minutes) and aortic cross clamp duration of (67±22) minutes (33 to 152 minutes). There were 9 perioperative deaths with a mortality rate of 3.5%. Angina pectoris of other cases are relief and Heart function improved greatly. Five years after operation, the percentage of cardiac function (New Yord Heart Association) class Ⅲ to Ⅳ patients decreased from 96.1%(244/254) to 9.9%(16/161). There was no significant difference in survival rate between linear group and patch plasty group at 1-, 3-, 5-yearspostoperatively (96%, 91%, 77% vs. 96%, 90%, 79%, P=0.562). Ejection fraction increased from (39±10)% (range: 22% to 50%) preoperatively to (46±6)% (range: 39% to 54%) 1-year postoperatively in the linear group, while increased from (38±13)% (range: 26% to 51%) preoperatively to (50±6)% (range: 39% to 55%) in the patch plasty group. Conclusions Left ventricular reconstruction is quite effective for patients with post-infarction left ventricular Aneurysm. The choice of operative approaches is determined by the size and range of ventricular Aneurysm. Both linear reconstruction and endoventricular patch plasty technique can got similarly surgical outcomes with near and late curative effect. Key words: Myocardial infarction; Heart Aneurysm; Cardiac surgical procedures
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Surgical treatment of post-infarction left ventricular Aneurysm: clinical analysis
Zhonghua yi xue za zhi, 2010Co-Authors: Xin Chen, Zhibing Qiu, Ying-shuo Jiang, Liming Wang, Hong-wei Shi, Xu-jun Chen, Fuhua Huang, Liqiong XiaoAbstract:Objective To explore the clinical experiences, efficacies and postoperative left ventricular remodeling changes of surgical ventricular reconstruction in the treatment of post-infarction left ventricular Aneurysm. Methods The investigators reviewed retrospectively the clinical data, operative approaches and follow-up outcomes of consecutive 194 patients with post-infarction left ventricular Aneurysm,who underwent surgical ventricular reconstruction between January 1997 and December 2009. There were 54cases in the linear group and 137 cases in the endoventricular patch plasty group. The changes of ventricular remodeling were measured by peri-operative and follow-up echocardiography. Results All patients underwent surgery with a mean cardiopulmonay bypass duration of ( 103 ± 35 ) min and aortic cross clamp duration of (62 ±26)min. There were 8 per-operative deaths with a mortality rate of 2.2%. Angina pectoris of other cases disappeared and Heart function greatly improved. After operation, the ventricular remodeling results showed that in the linear group, there was not significant difference in the changes of ventricular remodeling of post-op 2 weeks, 6 months, 1 year and 5 years versus pre-operation. However, in the endoventricular patch group, the changes of ventricular remodeling of post-op 2 weeks and follow-up 6months versus pre-operation were significantly reduced( P ＜0.05). End-systolic volume (LNESV) reduced from ( 129 ± 27 ) ml to ( 65 ± 8 ) ml and end-systolic volume index ( LVESVI ) decreased from ( 104 ± 14 )ml/m2 to (44 ± 6) ml/m2 and the subgroup of LVEF ＜ 35% was the most significant in the changes of LVESV and LVESVI. But LVEF improved significantly at post-operation and follow-up (from preoperation 42% ± 11% to 52% ± 7% during follow-up). Conclusions For patients with infarction left ventricular Aneurysm, left ventricular reconstruction is quite effective. The choice of operative approaches is determined ty the size and range of ventricular Aneurysm. Both string suture and endoventricular patch plasty technique can yield similarly satisfactory surgical outcomes. After operation, ventricular volume significantly decreases and cardiac function greatly improves. Key words: Myocardial infarction; Heart Aneurysm; Coronary artery bypass; Left ventricular reconstruction
S A Bozhenko - One of the best experts on this subject based on the ideXlab platform.
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A postinfarct Heart Aneurysm: its removal or revascularization?
Vestnik khirurgii imeni I. I. Grekova, 1997Co-Authors: Iu L Shevchenko, I A Borisov, S A BozhenkoAbstract:A conclusion about the hemodynamic significance of Aneurysm having the area of more than 30% of the left ventricle surface is made on the basis of an analysis of the pre- and post-operative parameters of the myocardium contractility and hemodynamic indices in 49 patients with postinfarction Aneurysm of the left ventricle (main group) and 26 patients with ischemic Heart disease without this complication (control group). Formation of the syndrome of chronic insufficiency of blood circulation in hemodynamically insignificant Aneurysm results from ischemia of the myocardium, rather than the Aneurysm as such. Improvement of blood supply to the myocardium as a result of its revascularization in such patients led to normalization of the left ventricle geometry.
Hong Zhai - One of the best experts on this subject based on the ideXlab platform.
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Assessment of the difference of myocardium strain between myocadial infarction and ventricular Aneurysm by two-dimensional speckle-tracking imaging in rabbits
Chinese Journal of Ultrasonography, 2012Co-Authors: Hong Zhai, Guliqiman·huojiaabudula, Li-na GuanAbstract:Objective To evaluate the difference of myocardium strain between myocadial infarction and ventricular Aneurysm (VA) by two-dimensional speckle-tracking imaging in rabbits.Methods 26 healthy New Zealand white rabbits were enrolled in this study,6 were put into the control group and 20 in the experimental group.models of myocardial infarction concomitant with VA were prepared by the ligation of the middle segment of left anterior descending artery and left circumflex artery.At 4 weeks after the procedure,according to the pathological inspect and echocardiography for whether VA formed,the experimental animals were divided into the VA group and the myocadial infarction group.Echocardiography was performed to measure the LV cavity size and cardiac function.Radial strain rate (SrR) and circumferential strain rate(SrC) indexes were measured by 2D-STI software for each animal at the level of apex in left ventricular short-axis view,and then calculated the strain rate decrease percentage in each segment.Results 1)Compared with the control group,SrR-S,SrR-E,SrR A,SrC-S,SrC-E,SrC-A in all segments were reduced significantly in the VA group and the myocadial infarction group (P ＜ 0.05),the VA group was the most significant.2)Compared with the myocadial infarction group,the strain rate decrease percentage of SrR-S,SrR-E,SrR-A,SrC-S,SrC-E,SrC-A in all segment had significant in the VA group.Comparison between the each section,the strain rate decrease percentage of SrR-Santerior wall,SrR-Sateral wall,SrC-Santerior wall,SrC-Slateral wall were the most significant.3)There were the tighter relationship between the strain rate decrease percentage of SrR-Santerior wall,SrC-Santerior wall,SrR-Slateral wall,SrC-Slateral wall and left ventricular ejection fraction (r =0.82,0.72,0.75,0.71,repectively,all P ＜ 0.05).4) The ROC curve analysis showed that when the strain rate decrease percentage was 60％ as the critical point,the strain rate decrease percentage of SrC-Santerior wall,SrC-Slateral wall,SrR-Santerior wall,SrR-Slateral wall had a sensitivity of 83.30 ％,84.40％,83.30％,67.70％％ and a specificity was 73.60％,78.20％％,69.70％,83.30％ for prognosis ventricular Aneurysm,repectively.Conclusions After ventricular Aneurysm formation,anterior and lateral wall myocardial strain were give priority to the myocardial mechanics reconstruction,thus systolic myocardial strain rate decrease percentage can be important indicator of infarction myocardial developing into ventricular Aneurysm. Key words: Echocardiography; Heart Aneurysm; Myocardial infarction; Ventricular function, left; Speckle-tracking imaging
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Assessment of left ventricular twist in rabbits with ventricular Aneurysm formed by two-dimensional speckle tracking echocardiography
Chinese Journal of Ultrasonography, 2012Co-Authors: Xue Yan, Li-na Guan, Hong Zhai, Yu-cheng ZhouAbstract:Objective To evaluate the influence on left ventricular(LV) twist,and the relationship between LV twist and function in the rabbits with ventricular Aneurysm formed after myocardial infarction by two-dimensional ultrasound speckle tracking imaging.Methods Twenty-six healthy rabbits were divided into two groups,six as control group,twenty as experimental group.The model of myocardial infarction and ventricular Aneurysm were established by ligaturing left anterior descending coronary artery and left circumflex artery.After four weeks,according to the pathological examination of whether ventricular Aneurysm formed or not,the experimental group was divided into myocardial infarct group and ventricular Aneurysm group.Echocardiography was performed to measure rotations (at the levels of mitral annulus and apex in LV short-axis view),LV twist,left ventricular cavity size and function.Results Compared with the myocardial infarct group,LV end-diastolic diameter(LVEDD) and LV end-diastolic volume(LVEDV) were larger in the ventricular Aneurysm group,but LV ejection fraction (LVEF),LV fractional shortening (LVFS),apical rotation and LV twist were lower in the ventricular Aneurysm group than the myocardial infarct group.Both apical rotation and LV twist had shown a great correlation with LVEF.The conclusion was also shown in the ROC curve that sensitivity and specificity of diagnosis cardiac dysfunction were 76.9％ and 80.0％ respectively when the apical rotation was 1.21°.Conclusions There was a closely relationship between the change of apical rotation and the LV systolic function.When the apical rotation dropped to 1.21°,an apparent decline of LV systolic function was implied. Key words: Echocardiography; Heart Aneurysm; Ventricular function,left; Rotation; Speckle tracking imaging
