The Experts below are selected from a list of 1215 Experts worldwide ranked by ideXlab platform
Dongfeng Niu - One of the best experts on this subject based on the ideXlab platform.
-
effectiveness of fibrin sealant as Hemostatic Technique in accelerating esd induced ulcer healing a retrospective study
Surgical Endoscopy and Other Interventional Techniques, 2020Co-Authors: Jing Wang, Yan Yan, Peng Yuan, Changqi Cao, Dongfeng NiuAbstract:Healing of gastric endoscopic submucosal dissection (ESD)-induced ulcer is critical for patient recovery. During ESD treatment, submucosal incisions are made with an electrosurgical knife to accomplish en bloc resections of superficial lesions. Nevertheless, excess electrocoagulation may decrease the blood supply of ESD-induced ulcer and delay the ulcer healing. The aim of this retrospective study was to evaluate the effectiveness of conservative electrocoagulation followed by porcine fibrin sealant (FS) as a wound microvessels-protective Hemostatic Technique in promoting the healing of ESD-induced ulcer. A total of 332 patients with early gastric cancer (EGCs), or gastric precancerous lesion and gastric adenoma were retrospectively analyzed. Propensity score matching was used to compensate for the differences in age, gender, tumor location, resected specimen area, and pathology. One-month ulcer healing rates and delayed bleeding were compared between two matched groups (combined hemostats group and electrocautery group). A total of 115 matched pairs were created after propensity score matching. There was no difference in tumor location, specimen surface area, tumor differentiation and invasion depth between groups. The completed healing rate 1 month after ESD was 44.3% in combined hemostats group and 30.4% in electrocautery group (P = 0.004). There was no difference in delayed massive bleeding rate between two groups (P = 0.300). In addition, based on the multivariate regression analysis for ulcer healing rate, the use of FS (OR, 0.348, 95% CI 0.196 − 0.617, P = 0.000) and larger specimen size (OR, 2.640, 95% CI 2.015–3.458, P = 0.000) were associated with nonhealing ulcer 1 month after ESD. Applying conservative electrocoagulation followed by porcine FS as a wound microvessels-protective Hemostatic Technique can promote ESD-induced ulcer healing without increasing delayed bleeding.
Jing Wang - One of the best experts on this subject based on the ideXlab platform.
-
effectiveness of fibrin sealant as a Hemostatic Technique in accelerating endoscopic submucosal dissection induced ulcer healing and preventing stricture in the esophagus a retrospective study
Oncology Letters, 2020Co-Authors: Jing WangAbstract:The aim of the present retrospective study was to evaluate the effectiveness of conservative electrocoagulation followed by porcine fibrin sealant (FS) as a protective Hemostatic Technique for wounded microvessels in promoting the healing of endoscopic submucosal dissection (ESD)-induced ulcer, and preventing esophageal strictures that follow ESD. A total of 203 patients with early esophageal cancer or precancerous lesions were retrospectively analyzed. The 1-month ulcer healing and stricture rates were compared between the two groups (combined hemostats and electrocautery groups). The 1-month complete healing rate was 77.0% in the combined hemostats group and 52.6% in the electrocautery group (P=0.003). The use of FS and a smaller resected range (<3/4 circumference) was associated with a better 1-month healing rate. For patients with a ≥3/4 circumference mucosal defect, the esophageal stricture rate was 31.6% (6/19) in the combined hemostats group and 25.0% (2/8) in the electrocautery group. There was no difference in the stricture rate (P=0.737) and dilation time (P=0.733) between the two groups. In conclusion, the application of conservative electrocoagulation followed by porcine FS as a wound-protection Technique promoted ESD-induced ulcer healing in the esophagus. However, this combined Hemostatic Technique was not superior to the conventional Hemostatic method in preventing post-ESD stricture in patients with large esophageal mucosal defects.
-
effectiveness of fibrin sealant as Hemostatic Technique in accelerating esd induced ulcer healing a retrospective study
Surgical Endoscopy and Other Interventional Techniques, 2020Co-Authors: Jing Wang, Yan Yan, Peng Yuan, Changqi Cao, Dongfeng NiuAbstract:Healing of gastric endoscopic submucosal dissection (ESD)-induced ulcer is critical for patient recovery. During ESD treatment, submucosal incisions are made with an electrosurgical knife to accomplish en bloc resections of superficial lesions. Nevertheless, excess electrocoagulation may decrease the blood supply of ESD-induced ulcer and delay the ulcer healing. The aim of this retrospective study was to evaluate the effectiveness of conservative electrocoagulation followed by porcine fibrin sealant (FS) as a wound microvessels-protective Hemostatic Technique in promoting the healing of ESD-induced ulcer. A total of 332 patients with early gastric cancer (EGCs), or gastric precancerous lesion and gastric adenoma were retrospectively analyzed. Propensity score matching was used to compensate for the differences in age, gender, tumor location, resected specimen area, and pathology. One-month ulcer healing rates and delayed bleeding were compared between two matched groups (combined hemostats group and electrocautery group). A total of 115 matched pairs were created after propensity score matching. There was no difference in tumor location, specimen surface area, tumor differentiation and invasion depth between groups. The completed healing rate 1 month after ESD was 44.3% in combined hemostats group and 30.4% in electrocautery group (P = 0.004). There was no difference in delayed massive bleeding rate between two groups (P = 0.300). In addition, based on the multivariate regression analysis for ulcer healing rate, the use of FS (OR, 0.348, 95% CI 0.196 − 0.617, P = 0.000) and larger specimen size (OR, 2.640, 95% CI 2.015–3.458, P = 0.000) were associated with nonhealing ulcer 1 month after ESD. Applying conservative electrocoagulation followed by porcine FS as a wound microvessels-protective Hemostatic Technique can promote ESD-induced ulcer healing without increasing delayed bleeding.
Jose M Palaciosjaraquemada - One of the best experts on this subject based on the ideXlab platform.
-
efficacy of surgical Techniques to control obstetric hemorrhage analysis of 539 cases
Acta Obstetricia et Gynecologica Scandinavica, 2011Co-Authors: Jose M PalaciosjaraquemadaAbstract:Objective. To analyze the efficacy of surgical Techniques to stop excessive obstetric bleeding. Design. Retrospective follow up. Setting. Center for Medical Education and Clinical Research and a total of twelve hospitals in Buenos Aires. Population. Five hundred and thirty-nine consecutive patients were included: 361 had placenta accreta–percreta, 114 uterine atony, 19 cervical scar pregnancy, 21 placenta previa and 24 uterine–cervical–vaginal tears. Three hundred and forty-seven women had surgery, of whom 192 were emergencies. Methods. The surgical Techniques included selective arterial ligation and compression procedures. The effectiveness of the Techniques was assessed by cessation of bleeding according to source. Follow up included hysteroscopy of 100 patients and magnetic resonance imaging of 341 patients. Main outcome measures. Strong association between topographical uterine irrigation areas and surgical Hemostatic Technique was established. Results. Hemorrhage stopped following arterial ligation or compression sutures in 499 women, but hysterectomy was needed in 40. In cervical, lower segment and upper vaginal bleeding, Cho's compression sutures proved to be an efficient and simple procedure. Most surgical Hemostatic failures that led to hysterectomy occurred in women with severe hemodynamic deterioration and coagulopathy. Two women died due to multiorgan failure. After surgery, 116 successful pregnancies were reported. Conclusions. Bilateral occlusions of the uterine artery or its branches were useful procedures to stop upper uterine bleeding. Square sutures were a simple and effective procedure to control lower genital tract bleeding.
Yan Yan - One of the best experts on this subject based on the ideXlab platform.
-
effectiveness of fibrin sealant as Hemostatic Technique in accelerating esd induced ulcer healing a retrospective study
Surgical Endoscopy and Other Interventional Techniques, 2020Co-Authors: Jing Wang, Yan Yan, Peng Yuan, Changqi Cao, Dongfeng NiuAbstract:Healing of gastric endoscopic submucosal dissection (ESD)-induced ulcer is critical for patient recovery. During ESD treatment, submucosal incisions are made with an electrosurgical knife to accomplish en bloc resections of superficial lesions. Nevertheless, excess electrocoagulation may decrease the blood supply of ESD-induced ulcer and delay the ulcer healing. The aim of this retrospective study was to evaluate the effectiveness of conservative electrocoagulation followed by porcine fibrin sealant (FS) as a wound microvessels-protective Hemostatic Technique in promoting the healing of ESD-induced ulcer. A total of 332 patients with early gastric cancer (EGCs), or gastric precancerous lesion and gastric adenoma were retrospectively analyzed. Propensity score matching was used to compensate for the differences in age, gender, tumor location, resected specimen area, and pathology. One-month ulcer healing rates and delayed bleeding were compared between two matched groups (combined hemostats group and electrocautery group). A total of 115 matched pairs were created after propensity score matching. There was no difference in tumor location, specimen surface area, tumor differentiation and invasion depth between groups. The completed healing rate 1 month after ESD was 44.3% in combined hemostats group and 30.4% in electrocautery group (P = 0.004). There was no difference in delayed massive bleeding rate between two groups (P = 0.300). In addition, based on the multivariate regression analysis for ulcer healing rate, the use of FS (OR, 0.348, 95% CI 0.196 − 0.617, P = 0.000) and larger specimen size (OR, 2.640, 95% CI 2.015–3.458, P = 0.000) were associated with nonhealing ulcer 1 month after ESD. Applying conservative electrocoagulation followed by porcine FS as a wound microvessels-protective Hemostatic Technique can promote ESD-induced ulcer healing without increasing delayed bleeding.
Peng Yuan - One of the best experts on this subject based on the ideXlab platform.
-
effectiveness of fibrin sealant as Hemostatic Technique in accelerating esd induced ulcer healing a retrospective study
Surgical Endoscopy and Other Interventional Techniques, 2020Co-Authors: Jing Wang, Yan Yan, Peng Yuan, Changqi Cao, Dongfeng NiuAbstract:Healing of gastric endoscopic submucosal dissection (ESD)-induced ulcer is critical for patient recovery. During ESD treatment, submucosal incisions are made with an electrosurgical knife to accomplish en bloc resections of superficial lesions. Nevertheless, excess electrocoagulation may decrease the blood supply of ESD-induced ulcer and delay the ulcer healing. The aim of this retrospective study was to evaluate the effectiveness of conservative electrocoagulation followed by porcine fibrin sealant (FS) as a wound microvessels-protective Hemostatic Technique in promoting the healing of ESD-induced ulcer. A total of 332 patients with early gastric cancer (EGCs), or gastric precancerous lesion and gastric adenoma were retrospectively analyzed. Propensity score matching was used to compensate for the differences in age, gender, tumor location, resected specimen area, and pathology. One-month ulcer healing rates and delayed bleeding were compared between two matched groups (combined hemostats group and electrocautery group). A total of 115 matched pairs were created after propensity score matching. There was no difference in tumor location, specimen surface area, tumor differentiation and invasion depth between groups. The completed healing rate 1 month after ESD was 44.3% in combined hemostats group and 30.4% in electrocautery group (P = 0.004). There was no difference in delayed massive bleeding rate between two groups (P = 0.300). In addition, based on the multivariate regression analysis for ulcer healing rate, the use of FS (OR, 0.348, 95% CI 0.196 − 0.617, P = 0.000) and larger specimen size (OR, 2.640, 95% CI 2.015–3.458, P = 0.000) were associated with nonhealing ulcer 1 month after ESD. Applying conservative electrocoagulation followed by porcine FS as a wound microvessels-protective Hemostatic Technique can promote ESD-induced ulcer healing without increasing delayed bleeding.