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Trendafilova Antoaneta - One of the best experts on this subject based on the ideXlab platform.

  • Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes
    Wiley-VHCA AG, 2019
    Co-Authors: Ozek Gulmira, Yur Suleyman, Goger Fatih, Ozek Temel, Anđelković, Boban D., Godjevac Dejan, Sofrenić Ivana, Aneva Ina, Todorova Milka, Trendafilova Antoaneta
    Abstract:

    Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H. ternatum were studied for their furanocoumarin content antioxidant potential and acetylcholinesterase and α-amylase inhibitory activities. Quantification of the furanocoumarins was performed by 1 H-NMR. Pimpinellin was found to be the main component in the roots of all studied species. Bergapten and imperatorin were the major compounds in the fruits of H. sibiricum and H. verticillatum, respectively, while byakangelicol dominated in H. angustisectum and H. ternatum fruits. The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavenging activity and TEAC (IC 50 0.58 mg/mL and 1.83 mm, respectively). The root extracts of H. verticillatum and H. angustisectum were found to be the most effective against acetylcholinesterase (IC 50 0.30 and 0.34 mg/mL, respectively). The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7) towards α-amylase.This is the peer-reviewed version of the following article:Ozek, G.; Yur, S.; Goger, F.; Ozek, T.; Andjelkovic, B.; Godjevac, D.; Sofrenic, I.; Aneva, I.; Todorova, M.; Trendafilova, A. Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum Verticillatum, Heracleum Sibiricum, Heracleum Angustisectum, and Heracleum Ternatum Extracts against Enzymes Involved in Alzheimer’s Disease and Type II Diabetes. Chemistry and Biodiversity 2019, 16 (4). [https://doi.org/10.1002/cbdv.201800672]

  • Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer’s Disease and Type II Diabetes
    Willey, 2019
    Co-Authors: Ozek Gulmira, Yur Suleyman, Goger Fatih, Ozek Temel, Anđelković, Boban D., Sofrenić Ivana, Aneva Ina, Todorova Milka, Gođevac Dejan, Trendafilova Antoaneta
    Abstract:

    Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H. ternatum were studied for their furanocoumarin content antioxidant potential and acetylcholinesterase and α-amylase inhibitory activities. Quantification of the furanocoumarins was performed by 1H-NMR. Pimpinellin was found to be the main component in the roots of all studied species. Bergapten and imperatorin were the major compounds in the fruits of H. sibiricum and H. verticillatum, respectively, while byakangelicol dominated in H. angustisectum and H. ternatum fruits. The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavenging activity and TEAC (IC50 0.58 mg/mL and 1.83 mM, respectively). The root extracts of H. verticillatum and H.angustisectum were found to be the most effective against acetylcholinesterase (IC50 0.30 and 0.34 mg/mL, respectively). The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7) towards α-amylase.The peer-reviewed version: [http://cer.ihtm.bg.ac.rs/handle/123456789/2899

  • Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer’s Disease and Type II Diabetes
    Willey, 2019
    Co-Authors: Ozek Gulmira, Yur Suleyman, Goger Fatih, Ozek Temel, Anđelković, Boban D., Sofrenić Ivana, Aneva Ina, Todorova Milka, Gođevac Dejan, Trendafilova Antoaneta
    Abstract:

    Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H. ternatum were studied fortheir furanocoumarin content antioxidant potential and acetylcholinesterase and α-amylase inhibitory activities.Quantification of the furanocoumarins was performed by 1H-NMR. Pimpinellin was found to be the maincomponent in the roots of all studied species. Bergapten and imperatorin were the major compounds in thefruits of H. sibiricum and H. verticillatum, respectively, while byakangelicol dominated in H. angustisectum and H.ternatum fruits. The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavengingactivity and TEAC (IC50 0.58 mg/mL and 1.83 mM, respectively). The root extracts of H. verticillatum and H.angustisectum were found to be the most effective against acetylcholinesterase (IC50 0.30 and 0.34 mg/mL,respectively). The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7)towards α-amylase.[http://cer.ihtm.bg.ac.rs/handle/123456789/2869

  • Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes
    Wiley-VHCA AG, 2019
    Co-Authors: Ozek Gulmira, Yur Suleyman, Goger Fatih, Ozek Temel, Anđelković, Boban D., Godjevac Dejan, Sofrenić Ivana, Aneva Ina, Todorova Milka, Trendafilova Antoaneta
    Abstract:

    Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H. ternatum were studied for their furanocoumarin content antioxidant potential and acetylcholinesterase and α-amylase inhibitory activities. Quantification of the furanocoumarins was performed by 1 H-NMR. Pimpinellin was found to be the main component in the roots of all studied species. Bergapten and imperatorin were the major compounds in the fruits of H. sibiricum and H. verticillatum, respectively, while byakangelicol dominated in H. angustisectum and H. ternatum fruits. The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavenging activity and TEAC (IC 50 0.58 mg/mL and 1.83 mm, respectively). The root extracts of H. verticillatum and H. angustisectum were found to be the most effective against acetylcholinesterase (IC 50 0.30 and 0.34 mg/mL, respectively). The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7) towards α-amylase.Peer-reviewed manuscript: [http://cherry.chem.bg.ac.rs/handle/123456789/2923

Sarka Jahodova - One of the best experts on this subject based on the ideXlab platform.

  • invasive species of Heracleum in europe an insight into genetic relationships and invasion history
    Diversity and Distributions, 2007
    Co-Authors: Petr Pyšek, Sarka Jahodova, Sviatlana Trybush, M Wade, A Karp
    Abstract:

    Several species of the genus Heracleum (Umbelliferae) were introduced into Europe from south-west Asia in the 19th century and are now widespread in many countries. At least three invasive taxa with unresolved relationships to one another are thought to occur in Europe: Heracleum mantegazzianum Sommier & Levier, H. sosnowskyi Manden, and H. persicum Desf. ex Fischer. They are tall plants forming extensive stands with a high cover. To elucidate genetic relationships between the species, and gain insight into their invasion history, samples were collected from native ranges in Asia and invaded ranges of the three species in Europe and analysed using amplified fragment length polymorphism. Five other Heracleum species were also studied and in total, 189 samples from 72 populations were analysed. The results confirmed that there are three distinct tall Heracleum species invading in Europe. Within each of the three species, plants collected in the invaded range are genetically close to those from their native ranges. A close genetic relationship between the three invasive Heracleum species in Europe was also found. A high overall genetic variability detected in the invaded range suggests that the majority of invading populations were not affected by a genetic bottleneck and that rapid evolution, drift, or hybridization played a role in genetic structuring of invading populations. For H. mantegazzianum, genetic distance of populations in the native range significantly decreased with geographical distance, but not in the invaded range. It is likely that the current pattern of genetic diversity in Europe resulted from multiple introductions of all three species.

Wolfgang Nentwig - One of the best experts on this subject based on the ideXlab platform.

  • phytophagous insects of giant hogweed Heracleum mantegazzianum apiaceae in invaded areas of europe and in its native area of the caucasus
    European Journal of Endocrinology, 2006
    Co-Authors: Steen Hansen, Jan Hattendorf, Ruediger Wittenberg, Sergey Ya Reznik, Charlotte Marie Bisgaard Nielsen, Hans Peter Ravn, Wolfgang Nentwig
    Abstract:

    Giant hogweed, Heracleum mantegazzianum (Apiaceae), was introduced from the Caucasus into Western Europe more than 150 years ago and later became an invasive weed which created major problems for European authorities. Phytophagous insects were collected in the native range of the giant hogweed (Caucasus) and were compared to those found on plants in the invaded parts of Europe. The list of herbivores was compiled from surveys of 27 localities in nine countries during two seasons. In addition, litera- ture records for herbivores were analysed for a total of 16 Heracleum species. We recorded a total of 265 herbivorous insects on Heracleum species and we analysed them to describe the herbivore assemblages, locate vacant niches, and identify the most host- specific herbivores on H. mantegazzianum. When combining our investigations with similar studies of herbivores on other invasive weeds, all studies show a higher proportion of specialist herbivores in the native habitats compared to the invaded areas, supporting the "enemy release hypothesis" (ERH). When analysing the relative size of the niches (measured as plant organ biomass), we found less herbivore species per biomass on the stem and roots, and more on the leaves (Fig. 5). Most herbivores were polyphagous gener- alists, some were found to be oligophagous (feeding within the same family of host plants) and a few had only Heracleum species as host plants (monophagous). None were known to feed exclusively on H. mantegazzianum. The oligophagous herbivores were restricted to a few taxonomic groups, especially within the Hemiptera, and were particularly abundant on this weed.

Petr Pyšek - One of the best experts on this subject based on the ideXlab platform.

  • invasive species of Heracleum in europe an insight into genetic relationships and invasion history
    Diversity and Distributions, 2007
    Co-Authors: Petr Pyšek, Sarka Jahodova, Sviatlana Trybush, M Wade, A Karp
    Abstract:

    Several species of the genus Heracleum (Umbelliferae) were introduced into Europe from south-west Asia in the 19th century and are now widespread in many countries. At least three invasive taxa with unresolved relationships to one another are thought to occur in Europe: Heracleum mantegazzianum Sommier & Levier, H. sosnowskyi Manden, and H. persicum Desf. ex Fischer. They are tall plants forming extensive stands with a high cover. To elucidate genetic relationships between the species, and gain insight into their invasion history, samples were collected from native ranges in Asia and invaded ranges of the three species in Europe and analysed using amplified fragment length polymorphism. Five other Heracleum species were also studied and in total, 189 samples from 72 populations were analysed. The results confirmed that there are three distinct tall Heracleum species invading in Europe. Within each of the three species, plants collected in the invaded range are genetically close to those from their native ranges. A close genetic relationship between the three invasive Heracleum species in Europe was also found. A high overall genetic variability detected in the invaded range suggests that the majority of invading populations were not affected by a genetic bottleneck and that rapid evolution, drift, or hybridization played a role in genetic structuring of invading populations. For H. mantegazzianum, genetic distance of populations in the native range significantly decreased with geographical distance, but not in the invaded range. It is likely that the current pattern of genetic diversity in Europe resulted from multiple introductions of all three species.

  • Invasion by Heracleum mantegazzianum in different habitats in the Czech Republic
    Journal of Vegetation Science, 1995
    Co-Authors: Petr Pyšek, Antonín Pyšek
    Abstract:

    . Heracleum mantegazzianum, a tall forb from the western Caucasus invaded several different habitats in the Czech Republic. The relation between invasion success and type of recipient habitat was studied in the Slavkovsku les hilly ridge, Czech Republic. The vegetation of 14 habitat types occurring in an area of ca. 25 km2 was analysed using phytosociological releves, and the invasion success of Heracleum (in terms of number of localities, area covered and proportion of available area occupied) was recorded separately in each of them. Site conditions were expressed indirectly using Ellenberg indicator values. The hypothesis tested was that Heracleum spreads in the majority of vegetation types regardless of the properties of the recipient vegetation. Community invasibility appeared to be affected by site conditions and the composition of the recipient vegetation. The species is not found in acidic habitats. Disturbed habitats with good possibilities of dispersal for Heracleum seeds are more easily invaded. Communities with a higher proportion of phanerophytes and of species with CS (Competitive/Stresstolerating) strategy were more resistant to invasion. The invasion success was bigger in sites with increased possibilities of spread for Heracleum diaspores. Communities invaded by Heracleum had a lower species diversity and a higher indicator value for nitrogen than not-invaded stands. It appears that species contributing to community resistance against invasion of Heracleum, or capable of persisting in Heracleum-invaded stands, have similar ecological requirements but a different life strategy to the invader.

Ozek Gulmira - One of the best experts on this subject based on the ideXlab platform.

  • Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes
    Wiley-VHCA AG, 2019
    Co-Authors: Ozek Gulmira, Yur Suleyman, Goger Fatih, Ozek Temel, Anđelković, Boban D., Godjevac Dejan, Sofrenić Ivana, Aneva Ina, Todorova Milka, Trendafilova Antoaneta
    Abstract:

    Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H. ternatum were studied for their furanocoumarin content antioxidant potential and acetylcholinesterase and α-amylase inhibitory activities. Quantification of the furanocoumarins was performed by 1 H-NMR. Pimpinellin was found to be the main component in the roots of all studied species. Bergapten and imperatorin were the major compounds in the fruits of H. sibiricum and H. verticillatum, respectively, while byakangelicol dominated in H. angustisectum and H. ternatum fruits. The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavenging activity and TEAC (IC 50 0.58 mg/mL and 1.83 mm, respectively). The root extracts of H. verticillatum and H. angustisectum were found to be the most effective against acetylcholinesterase (IC 50 0.30 and 0.34 mg/mL, respectively). The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7) towards α-amylase.This is the peer-reviewed version of the following article:Ozek, G.; Yur, S.; Goger, F.; Ozek, T.; Andjelkovic, B.; Godjevac, D.; Sofrenic, I.; Aneva, I.; Todorova, M.; Trendafilova, A. Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum Verticillatum, Heracleum Sibiricum, Heracleum Angustisectum, and Heracleum Ternatum Extracts against Enzymes Involved in Alzheimer’s Disease and Type II Diabetes. Chemistry and Biodiversity 2019, 16 (4). [https://doi.org/10.1002/cbdv.201800672]

  • Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer’s Disease and Type II Diabetes
    Willey, 2019
    Co-Authors: Ozek Gulmira, Yur Suleyman, Goger Fatih, Ozek Temel, Anđelković, Boban D., Sofrenić Ivana, Aneva Ina, Todorova Milka, Gođevac Dejan, Trendafilova Antoaneta
    Abstract:

    Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H. ternatum were studied for their furanocoumarin content antioxidant potential and acetylcholinesterase and α-amylase inhibitory activities. Quantification of the furanocoumarins was performed by 1H-NMR. Pimpinellin was found to be the main component in the roots of all studied species. Bergapten and imperatorin were the major compounds in the fruits of H. sibiricum and H. verticillatum, respectively, while byakangelicol dominated in H. angustisectum and H. ternatum fruits. The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavenging activity and TEAC (IC50 0.58 mg/mL and 1.83 mM, respectively). The root extracts of H. verticillatum and H.angustisectum were found to be the most effective against acetylcholinesterase (IC50 0.30 and 0.34 mg/mL, respectively). The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7) towards α-amylase.The peer-reviewed version: [http://cer.ihtm.bg.ac.rs/handle/123456789/2899

  • Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer’s Disease and Type II Diabetes
    Willey, 2019
    Co-Authors: Ozek Gulmira, Yur Suleyman, Goger Fatih, Ozek Temel, Anđelković, Boban D., Sofrenić Ivana, Aneva Ina, Todorova Milka, Gođevac Dejan, Trendafilova Antoaneta
    Abstract:

    Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H. ternatum were studied fortheir furanocoumarin content antioxidant potential and acetylcholinesterase and α-amylase inhibitory activities.Quantification of the furanocoumarins was performed by 1H-NMR. Pimpinellin was found to be the maincomponent in the roots of all studied species. Bergapten and imperatorin were the major compounds in thefruits of H. sibiricum and H. verticillatum, respectively, while byakangelicol dominated in H. angustisectum and H.ternatum fruits. The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavengingactivity and TEAC (IC50 0.58 mg/mL and 1.83 mM, respectively). The root extracts of H. verticillatum and H.angustisectum were found to be the most effective against acetylcholinesterase (IC50 0.30 and 0.34 mg/mL,respectively). The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7)towards α-amylase.[http://cer.ihtm.bg.ac.rs/handle/123456789/2869

  • Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes
    Wiley-VHCA AG, 2019
    Co-Authors: Ozek Gulmira, Yur Suleyman, Goger Fatih, Ozek Temel, Anđelković, Boban D., Godjevac Dejan, Sofrenić Ivana, Aneva Ina, Todorova Milka, Trendafilova Antoaneta
    Abstract:

    Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H. ternatum were studied for their furanocoumarin content antioxidant potential and acetylcholinesterase and α-amylase inhibitory activities. Quantification of the furanocoumarins was performed by 1 H-NMR. Pimpinellin was found to be the main component in the roots of all studied species. Bergapten and imperatorin were the major compounds in the fruits of H. sibiricum and H. verticillatum, respectively, while byakangelicol dominated in H. angustisectum and H. ternatum fruits. The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavenging activity and TEAC (IC 50 0.58 mg/mL and 1.83 mm, respectively). The root extracts of H. verticillatum and H. angustisectum were found to be the most effective against acetylcholinesterase (IC 50 0.30 and 0.34 mg/mL, respectively). The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7) towards α-amylase.Peer-reviewed manuscript: [http://cherry.chem.bg.ac.rs/handle/123456789/2923