The Experts below are selected from a list of 90 Experts worldwide ranked by ideXlab platform
Reza Malekzadeh - One of the best experts on this subject based on the ideXlab platform.
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Herpes Simplex Virus Encephalitis During Immunosuppressive Treatment of Ulcerative Colitis
Medscape general medicine, 2004Co-Authors: Farhad Zamani, Seyedmeysam Alimohamadi, Seyedhosein Mirmadjlessi, M Mohammadnezhad, Reza MalekzadehAbstract:Today, with the advent of new medications, treatment of Ulcerative colitis (UC) has been markedly improved. Immunosuppressive drugs used in therapy predispose patients to opportunistic infections. A 22-year-old woman was admitted to emergency department due to acute exacerbation of UC and decreased level of consciousness. She was under treatment with 5-aminosalicylate, prednisolone and azathioprine. In neurological evaluation, patient had cerebral herniation. Non-contrast CT scan revealed multiple hemorrhagic areas in both frontal lobes. Right frontal craniotomy was performed emergently. Histopathologic evaluation of brain tissue was reported as "Herpes simplex Encephalitis". Polymerase chain reaction (PCR) assay was also positive for HSV DNA. Immunosuppressive drugs such as azathioprine have a pivotal role in the treatment of resistant and/or severe cases of UC. Prevalence of infectious complications was reported to be 7.4%, 1.8% of which were severe (including Herpes Zoster Encephalitis) .Our review of literature indicates that no case of Herpes simplex Encephalitis following immunosuppressive therapy for UC has been reported. Govaresh 2004; 9: 45-7
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Herpes Simplex Virus Encephalitis During Immunosuppressive Treatment of Ulcerative Colitis
2004Co-Authors: Farhad Zamani, Seyedmeysam Alimohamadi, Seyedhosein Mirmadjlessi, Mehdi Mohamadnejad, Reza MalekzadehAbstract:Today, with the advent of new medications, treatment of Ulcerative colitis (UC) has been markedly improved. Immunosuppressive drugs used in therapy predispose patients to opportunistic infections. A 22-year-old woman was admitted to emergency department due to acute exacerbation of UC and decreased level of consciousness. She was under treatment with 5-aminosalicylate, prednisolone and azathioprine. In neurological evaluation, patient had cerebral herniation. Non-contrast CT scan revealed multiple hemorrhagic areas in both frontal lobes. Right frontal craniotomy was performed emergently. Histopathologic evaluation of brain tissue was reported as "Herpes simplex Encephalitis". Polymerase chain reaction (PCR) assay was also positive for HSV DNA. Immunosuppressive drugs such as azathioprine have a pivotal role in the treatment of resistant and/or severe cases of UC. Prevalence of infectious complications was reported to be 7.4%, 1.8% of which were severe (including Herpes Zoster Encephalitis) .Our review of literature indicates that no case of Herpes simplex Encephalitis following immunosuppressive therapy for UC has been reported.
Bassel Abou-khalil - One of the best experts on this subject based on the ideXlab platform.
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Pilomotor seizures: a video case report
Epileptic Disorders, 2012Co-Authors: Mohamad Ayman Haykal, Bassel Abou-khalilAbstract:Piloerection is a rare ictal manifestation usually associated with temporal lobe epilepsy. We present video and electrographic documentation of pilomotor seizures in a 75-year-old man with left temporal lobe epilepsy and remote Herpes Zoster Encephalitis. In general, piloerection is most often localised to the temporal lobe. Unilateral piloerection is usually associated with an ipsilateral ictal onset. Bilateral piloerection has a less certain lateralising value, although earlier reports suggest left hemispheric predominance.
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Pilomotor seizures: a video case report
Epileptic disorders : international epilepsy journal with videotape, 2012Co-Authors: Mohamad Ayman Haykal, Bassel Abou-khalilAbstract:Piloerection is a rare ictal manifestation usually associated with temporal lobe epilepsy. We present video and electrographic documentation of pilomotor seizures in a 75-year-old man with left temporal lobe epilepsy and remote Herpes Zoster Encephalitis. In general, piloerection is most often localised to the temporal lobe. Unilateral piloerection is usually associated with an ipsilateral ictal onset. Bilateral piloerection has a less certain lateralising value, although earlier reports suggest left hemispheric predominance [Published with videosequences].
Farhad Zamani - One of the best experts on this subject based on the ideXlab platform.
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Herpes Simplex Virus Encephalitis During Immunosuppressive Treatment of Ulcerative Colitis
Medscape general medicine, 2004Co-Authors: Farhad Zamani, Seyedmeysam Alimohamadi, Seyedhosein Mirmadjlessi, M Mohammadnezhad, Reza MalekzadehAbstract:Today, with the advent of new medications, treatment of Ulcerative colitis (UC) has been markedly improved. Immunosuppressive drugs used in therapy predispose patients to opportunistic infections. A 22-year-old woman was admitted to emergency department due to acute exacerbation of UC and decreased level of consciousness. She was under treatment with 5-aminosalicylate, prednisolone and azathioprine. In neurological evaluation, patient had cerebral herniation. Non-contrast CT scan revealed multiple hemorrhagic areas in both frontal lobes. Right frontal craniotomy was performed emergently. Histopathologic evaluation of brain tissue was reported as "Herpes simplex Encephalitis". Polymerase chain reaction (PCR) assay was also positive for HSV DNA. Immunosuppressive drugs such as azathioprine have a pivotal role in the treatment of resistant and/or severe cases of UC. Prevalence of infectious complications was reported to be 7.4%, 1.8% of which were severe (including Herpes Zoster Encephalitis) .Our review of literature indicates that no case of Herpes simplex Encephalitis following immunosuppressive therapy for UC has been reported. Govaresh 2004; 9: 45-7
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Herpes Simplex Virus Encephalitis During Immunosuppressive Treatment of Ulcerative Colitis
2004Co-Authors: Farhad Zamani, Seyedmeysam Alimohamadi, Seyedhosein Mirmadjlessi, Mehdi Mohamadnejad, Reza MalekzadehAbstract:Today, with the advent of new medications, treatment of Ulcerative colitis (UC) has been markedly improved. Immunosuppressive drugs used in therapy predispose patients to opportunistic infections. A 22-year-old woman was admitted to emergency department due to acute exacerbation of UC and decreased level of consciousness. She was under treatment with 5-aminosalicylate, prednisolone and azathioprine. In neurological evaluation, patient had cerebral herniation. Non-contrast CT scan revealed multiple hemorrhagic areas in both frontal lobes. Right frontal craniotomy was performed emergently. Histopathologic evaluation of brain tissue was reported as "Herpes simplex Encephalitis". Polymerase chain reaction (PCR) assay was also positive for HSV DNA. Immunosuppressive drugs such as azathioprine have a pivotal role in the treatment of resistant and/or severe cases of UC. Prevalence of infectious complications was reported to be 7.4%, 1.8% of which were severe (including Herpes Zoster Encephalitis) .Our review of literature indicates that no case of Herpes simplex Encephalitis following immunosuppressive therapy for UC has been reported.
Ulhas N Jajoo - One of the best experts on this subject based on the ideXlab platform.
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Herpes Zoster Encephalitis presenting as multiple cerebral hemorrhages – a rare presentation: a case report
Journal of Medical Case Reports, 2013Co-Authors: Amrish Saxena, Benjamine Khiangte, Iadarilang Tiewsoh, Ulhas N JajooAbstract:Introduction An infection by Herpes Zoster virus is a common and important cause of Encephalitis. Herpes Zoster virus Encephalitis if not treated promptly can result in significant morbidity and mortality. The diagnosis of Herpes Zoster virus Encephalitis is based on clinical history, examination, neuroradiological imaging (magnetic resonance imaging and/or computed tomography scan), cerebrospinal fluid analysis and identification of the pathogen in cerebrospinal fluid by polymerase chain reaction amplification and/or anti-Herpes Zoster virus immunoglobulin G antibody in cerebrospinal fluid. Although ischemic intracerebral infarcts in patients with Herpes Zoster virus Encephalitis or vasculopathy are reported in the literature, multiple intracerebral hemorrhages as a complication of Herpes Zoster virus Encephalitis in an immunocompetent individual are extremely rare. Case presentation A 40-year-old Indian man presented with an acute history of four episodes of seizures, fever, headache, drowsiness, focal neurological deficits and vesicular eruptions over the abdomen in a typical dermatomal distribution. His head computed tomography scan revealed multiple cerebral hemorrhages. Investigations (positive ratio between the cerebrospinal fluid/serum quotients for anti-Herpes Zoster virus immunoglobulin G and total immunoglobulin G antibodies) established its infective origin due to Herpes Zoster virus. He developed bilateral pneumonia during the hospital course. He had an excellent recovery following a 2 weeks’ course of intravenous acyclovir. Conclusion Herpes Zoster virus Encephalitis or vasculopathy is a rare cause of multiple intracerebral hemorrhages and must be considered in the differential diagnosis of patients presenting with an acute history of fever, altered consciousness, and focal neurologic deficits with history of a typical herpetic rash. Its prompt recognition and treatment could alter the course of illness.
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Herpes Zoster Encephalitis presenting as multiple cerebral hemorrhages a rare presentation a case report
Journal of Medical Case Reports, 2013Co-Authors: Amrish Saxena, Benjamine Khiangte, Iadarilang Tiewsoh, Ulhas N JajooAbstract:Introduction: An infection by Herpes Zoster virus is a common and important cause of Encephalitis. Herpes Zoster virus Encephalitis if not treated promptly can result in significant morbidity and mortality. The diagnosis of Herpes Zoster virus Encephalitis is based on clinical history, examination, neuroradiological imaging (magnetic resonance imaging and/or computed tomography scan), cerebrospinal fluid analysis and identification of the pathogen in cerebrospinal fluid by polymerase chain reaction amplification and/or anti-Herpes Zoster virus immunoglobulin G antibody in cerebrospinal fluid. Although ischemic intracerebral infarcts in patients with Herpes Zoster virus Encephalitis or vasculopathy are reported in the literature, multiple intracerebral hemorrhages as a complication of Herpes Zoster virus Encephalitis in an immunocompetent individual are extremely rare. Case presentation: A 40-year-old Indian man presented with an acute history of four episodes of seizures, fever, headache, drowsiness, focal neurological deficits and vesicular eruptions over the abdomen in a typical dermatomal distribution. His head computed tomography scan revealed multiple cerebral hemorrhages. Investigations (positive ratio between the cerebrospinal fluid/serum quotients for anti-Herpes Zoster virus immunoglobulin G and total immunoglobulin G antibodies) established its infective origin due to Herpes Zoster virus. He developed bilateral pneumonia during the hospital course. He had an excellent recovery following a 2 weeks’ course of intravenous acyclovir. Conclusion: Herpes Zoster virus Encephalitis or vasculopathy is a rare cause of multiple intracerebral hemorrhages and must be considered in the differential diagnosis of patients presenting with an acute history of fever, altered consciousness, and focal neurologic deficits with history of a typical herpetic rash. Its prompt recognition and treatment could alter the course of illness.
Mohamad Ayman Haykal - One of the best experts on this subject based on the ideXlab platform.
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Pilomotor seizures: a video case report
Epileptic Disorders, 2012Co-Authors: Mohamad Ayman Haykal, Bassel Abou-khalilAbstract:Piloerection is a rare ictal manifestation usually associated with temporal lobe epilepsy. We present video and electrographic documentation of pilomotor seizures in a 75-year-old man with left temporal lobe epilepsy and remote Herpes Zoster Encephalitis. In general, piloerection is most often localised to the temporal lobe. Unilateral piloerection is usually associated with an ipsilateral ictal onset. Bilateral piloerection has a less certain lateralising value, although earlier reports suggest left hemispheric predominance.
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Pilomotor seizures: a video case report
Epileptic disorders : international epilepsy journal with videotape, 2012Co-Authors: Mohamad Ayman Haykal, Bassel Abou-khalilAbstract:Piloerection is a rare ictal manifestation usually associated with temporal lobe epilepsy. We present video and electrographic documentation of pilomotor seizures in a 75-year-old man with left temporal lobe epilepsy and remote Herpes Zoster Encephalitis. In general, piloerection is most often localised to the temporal lobe. Unilateral piloerection is usually associated with an ipsilateral ictal onset. Bilateral piloerection has a less certain lateralising value, although earlier reports suggest left hemispheric predominance [Published with videosequences].