The Experts below are selected from a list of 5094 Experts worldwide ranked by ideXlab platform
Francesco P. Cappuccio - One of the best experts on this subject based on the ideXlab platform.
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ESC CardioMed - Sodium and Potassium Intake, blood pressure, and cardiovascular prevention
ESC CardioMed, 2018Co-Authors: Francesco P. CappuccioAbstract:Salt consumption is now much greater than needed for survival. High salt Intake increases blood pressure in both animals and humans. Conversely, a reduction in salt Intake causes a dose-dependent reduction in blood pressure in men and women of all ages and ethnic groups, and in patients already on medication. The risk of strokes and heart attacks rises with increasing blood pressure, but can be decreased by antihypertensive drugs. However, most cardiovascular disease events occur in individuals with ‘normal’ blood pressure levels. Non-pharmacological prevention is therefore the only option to reduce such events. Reduction in population salt Intake reduces the number of vascular events. It is one of the most important public health measures to reduce the global cardiovascular burden. Salt reduction policies are powerful, rapid, equitable, and cost saving. The World Health Organization recommends reducing salt consumption below 5 g per day aiming at a global 30% reduction by 2025. A High Potassium Intake lowers blood pressure in people with and without hypertension. Its beneficial effects extend beyond blood pressure, and may include a reduction in the risk of stroke (independent of blood pressure changes). Potassium Intake in the Western world is relatively low, and a lower Potassium Intake is associated with increased risks of cardiovascular disease, especially stroke. A moderate increase in Potassium Intake, either as supplement or with diet, reduces blood pressure, and the World Health Organization has issued global recommendations for a target dietary Potassium Intake of at least 90 mmol/day (≥3510 mg/day) for adults.
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Sodium and Potassium Intake in Healthy Adults in Thessaloniki Greater Metropolitan Area—The Salt Intake in Northern Greece (SING) Study
Nutrients, 2017Co-Authors: Eleni Vasara, Georgios Marakis, João Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos E. Rodopaios, Alexandra A. Koulouri, Francesco P. CappuccioAbstract:A reduction in population sodium (as salt) consumption is a global health priority, as well as one of the most cost-effective strategies to reduce the burden of cardiovascular disease. High Potassium Intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and Potassium Intake. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and Potassium Intakes in a sample of healthy adults in northern Greece, and to determine whether adherence to a Mediterranean diet is related to different sodium Intakes or sodium-to-Potassium ratio. A cross-sectional survey was carried out in the Thessaloniki greater metropolitan area (northern Greece) (n = 252, aged 18–75 years, 45.2% males). Participants’ dietary sodium and Potassium Intakes were determined by 24-hour urinary sodium and Potassium excretions. In addition, we estimated their adherence to Mediterranean diet by the use of an 11-item MedDietScore (range 0–55). The mean sodium excretion was 175 (SD 72) mmol/day, equivalent to 4220 (1745) mg of sodium or 10.7 (4.4) g of salt per day, and the Potassium excretion was 65 (25) mmol/day, equivalent to 3303 (1247) mg per day. Men had Higher sodium and Potassium excretions compared to women. Only 5.6% of the sample had salt Intake
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sodium and Potassium Intake in healthy adults in thessaloniki greater metropolitan area the salt Intake in northern greece sing study
Nutrients, 2017Co-Authors: Eleni Vasara, Georgios Marakis, João Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos E. Rodopaios, Alexandra A. Koulouri, Francesco P. CappuccioAbstract:A reduction in population sodium (as salt) consumption is a global health priority, as well as one of the most cost-effective strategies to reduce the burden of cardiovascular disease. High Potassium Intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and Potassium Intake. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and Potassium Intakes in a sample of healthy adults in northern Greece, and to determine whether adherence to a Mediterranean diet is related to different sodium Intakes or sodium-to-Potassium ratio. A cross-sectional survey was carried out in the Thessaloniki greater metropolitan area (northern Greece) (n = 252, aged 18–75 years, 45.2% males). Participants’ dietary sodium and Potassium Intakes were determined by 24-hour urinary sodium and Potassium excretions. In addition, we estimated their adherence to Mediterranean diet by the use of an 11-item MedDietScore (range 0–55). The mean sodium excretion was 175 (SD 72) mmol/day, equivalent to 4220 (1745) mg of sodium or 10.7 (4.4) g of salt per day, and the Potassium excretion was 65 (25) mmol/day, equivalent to 3303 (1247) mg per day. Men had Higher sodium and Potassium excretions compared to women. Only 5.6% of the sample had salt Intake <5 g/day, which is the target Intake recommended by the World Health Organization. Mean sodium-to-Potassium excretion ratio was 2.82 (1.07). There was no significant difference in salt or Potassium Intake or their ratio across MedDietScore quartiles. No significant relationships were found between salt Intake and adherence to a Mediterranean diet, suggesting that the perception of the health benefits of the Mediterranean diet does not hold when referring to salt consumption. These results suggest the need for a larger, nation-wide survey on salt Intake in Greece and underline the importance of continuation of salt reduction initiatives in Greece.
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Sodium and Potassium Intake in Healthy Adults in Thessaloniki Greater Metropolitan Area—The SING (Salt Intake in Northern Greece) Study
2017Co-Authors: Eleni Vasara, Georgios Marakis, João Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos E. Rodopaios, Alexandra A. Koulouri, Francesco P. CappuccioAbstract:A reduction in population sodium (as salt) consumption is one of the most cost-effective strategies to reduce the burden of cardiovascular disease and it is a global health priority. High Potassium Intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and Potassium Intakes. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and Potassium Intakes in a sample of healthy adults in northern Greece and to determine whether adherence to a Mediterranean diet is related to different sodium Intakes or sodium-to-Potassium ratio. A cross-sectional survey was carried out in Thessaloniki greater metropolitan area (northern Greece) (n=252, aged 18-75 years, 45.2% males). Participants’ dietary sodium and Potassium Intakes were determined by 24h urinary sodium and Potassium excretions. In addition, we estimated their adherence to Mediterranean diet by the use of an 11-item MedDietScore (range 0-55). The mean sodium excretion was 175 (SD 72) mmol/day, equivalent to 4,220 (1,745) mg of sodium or 10.7 (4.4) g of salt per day and Potassium excretion was 65 (25) mmol/day, equivalent to 3,303 (1,247) mg/day. Men had Higher sodium and Potassium excretions compared to women. Only 5.6% of the sample had salt Intake <5g/d, which is the target Intake recommended by the WHO. Mean sodium-to-Potassium Intake ratio was 1.34 (0.51). There was no significant difference in salt or Potassium Intake or their ratio across MedDietScore quartiles. No significant relationships were found between salt Intake and adherence to Mediterranean diet, suggesting that the perception of the health benefits of the Mediterranean diet does not hold when referring to salt consumption. These results suggest the need for a larger nation-wide survey on salt Intake in Greece and underline the importance of continuation of salt reduction initiatives in Greece.
Eleni Vasara - One of the best experts on this subject based on the ideXlab platform.
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Sodium and Potassium Intake in Healthy Adults in Thessaloniki Greater Metropolitan Area—The Salt Intake in Northern Greece (SING) Study
Nutrients, 2017Co-Authors: Eleni Vasara, Georgios Marakis, João Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos E. Rodopaios, Alexandra A. Koulouri, Francesco P. CappuccioAbstract:A reduction in population sodium (as salt) consumption is a global health priority, as well as one of the most cost-effective strategies to reduce the burden of cardiovascular disease. High Potassium Intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and Potassium Intake. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and Potassium Intakes in a sample of healthy adults in northern Greece, and to determine whether adherence to a Mediterranean diet is related to different sodium Intakes or sodium-to-Potassium ratio. A cross-sectional survey was carried out in the Thessaloniki greater metropolitan area (northern Greece) (n = 252, aged 18–75 years, 45.2% males). Participants’ dietary sodium and Potassium Intakes were determined by 24-hour urinary sodium and Potassium excretions. In addition, we estimated their adherence to Mediterranean diet by the use of an 11-item MedDietScore (range 0–55). The mean sodium excretion was 175 (SD 72) mmol/day, equivalent to 4220 (1745) mg of sodium or 10.7 (4.4) g of salt per day, and the Potassium excretion was 65 (25) mmol/day, equivalent to 3303 (1247) mg per day. Men had Higher sodium and Potassium excretions compared to women. Only 5.6% of the sample had salt Intake
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sodium and Potassium Intake in healthy adults in thessaloniki greater metropolitan area the salt Intake in northern greece sing study
Nutrients, 2017Co-Authors: Eleni Vasara, Georgios Marakis, João Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos E. Rodopaios, Alexandra A. Koulouri, Francesco P. CappuccioAbstract:A reduction in population sodium (as salt) consumption is a global health priority, as well as one of the most cost-effective strategies to reduce the burden of cardiovascular disease. High Potassium Intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and Potassium Intake. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and Potassium Intakes in a sample of healthy adults in northern Greece, and to determine whether adherence to a Mediterranean diet is related to different sodium Intakes or sodium-to-Potassium ratio. A cross-sectional survey was carried out in the Thessaloniki greater metropolitan area (northern Greece) (n = 252, aged 18–75 years, 45.2% males). Participants’ dietary sodium and Potassium Intakes were determined by 24-hour urinary sodium and Potassium excretions. In addition, we estimated their adherence to Mediterranean diet by the use of an 11-item MedDietScore (range 0–55). The mean sodium excretion was 175 (SD 72) mmol/day, equivalent to 4220 (1745) mg of sodium or 10.7 (4.4) g of salt per day, and the Potassium excretion was 65 (25) mmol/day, equivalent to 3303 (1247) mg per day. Men had Higher sodium and Potassium excretions compared to women. Only 5.6% of the sample had salt Intake <5 g/day, which is the target Intake recommended by the World Health Organization. Mean sodium-to-Potassium excretion ratio was 2.82 (1.07). There was no significant difference in salt or Potassium Intake or their ratio across MedDietScore quartiles. No significant relationships were found between salt Intake and adherence to a Mediterranean diet, suggesting that the perception of the health benefits of the Mediterranean diet does not hold when referring to salt consumption. These results suggest the need for a larger, nation-wide survey on salt Intake in Greece and underline the importance of continuation of salt reduction initiatives in Greece.
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Sodium and Potassium Intake in Healthy Adults in Thessaloniki Greater Metropolitan Area—The SING (Salt Intake in Northern Greece) Study
2017Co-Authors: Eleni Vasara, Georgios Marakis, João Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos E. Rodopaios, Alexandra A. Koulouri, Francesco P. CappuccioAbstract:A reduction in population sodium (as salt) consumption is one of the most cost-effective strategies to reduce the burden of cardiovascular disease and it is a global health priority. High Potassium Intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and Potassium Intakes. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and Potassium Intakes in a sample of healthy adults in northern Greece and to determine whether adherence to a Mediterranean diet is related to different sodium Intakes or sodium-to-Potassium ratio. A cross-sectional survey was carried out in Thessaloniki greater metropolitan area (northern Greece) (n=252, aged 18-75 years, 45.2% males). Participants’ dietary sodium and Potassium Intakes were determined by 24h urinary sodium and Potassium excretions. In addition, we estimated their adherence to Mediterranean diet by the use of an 11-item MedDietScore (range 0-55). The mean sodium excretion was 175 (SD 72) mmol/day, equivalent to 4,220 (1,745) mg of sodium or 10.7 (4.4) g of salt per day and Potassium excretion was 65 (25) mmol/day, equivalent to 3,303 (1,247) mg/day. Men had Higher sodium and Potassium excretions compared to women. Only 5.6% of the sample had salt Intake <5g/d, which is the target Intake recommended by the WHO. Mean sodium-to-Potassium Intake ratio was 1.34 (0.51). There was no significant difference in salt or Potassium Intake or their ratio across MedDietScore quartiles. No significant relationships were found between salt Intake and adherence to Mediterranean diet, suggesting that the perception of the health benefits of the Mediterranean diet does not hold when referring to salt consumption. These results suggest the need for a larger nation-wide survey on salt Intake in Greece and underline the importance of continuation of salt reduction initiatives in Greece.
Wenhui Wang - One of the best experts on this subject based on the ideXlab platform.
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Deletion of Kir5.1 Impairs Renal Ability to Excrete Potassium During Increased Dietary Potassium Intake
Journal of The American Society of Nephrology, 2019Co-Authors: Peng Wu, Xiao-tong Su, Dan-dan Zhang, Wenhui WangAbstract:Background The basolateral Potassium channel in the distal convoluted tubule (DCT), comprising the inwardly rectifying Potassium channel Kir4.1/Kir5.1 heterotetramer, plays a key role in mediating the effect of dietary Potassium Intake on the thiazide-sensitive NaCl cotransporter (NCC). The role of Kir5.1 (encoded by Kcnj16) in mediating effects of dietary Potassium Intake on the NCC and renal Potassium excretion is unknown. Methods We used electrophysiology, renal clearance, and immunoblotting to study Kir4.1 in the DCT and NCC in Kir5.1 knockout (Kcnj16-/- ) and wild-type (Kcnj16+/+ ) mice fed with normal, High, or low Potassium diets. Results We detected a 40-pS and 20-pS Potassium channel in the basolateral membrane of the DCT in wild-type and knockout mice, respectively. Compared with wild-type, Kcnj16-/- mice fed a normal Potassium diet had Higher basolateral Potassium conductance, a more negative DCT membrane potential, Higher expression of phosphorylated NCC (pNCC) and total NCC (tNCC), and augmented thiazide-induced natriuresis. Neither High- nor low-Potassium diets affected the basolateral DCT's Potassium conductance and membrane potential in Kcnj16-/- mice. Although High Potassium reduced and low Potassium increased the expression of pNCC and tNCC in wild-type mice, these effects were absent in Kcnj16-/- mice. High Potassium Intake inhibited and low Intake augmented thiazide-induced natriuresis in wild-type but not in Kcnj16-/- mice. Compared with wild-type, Kcnj16-/- mice with normal Potassium Intake had slightly lower plasma Potassium but were more hyperkalemic with prolonged High Potassium Intake and more hypokalemic during Potassium restriction. Conclusions Kir5.1 is essential for dietary Potassium's effect on NCC and for maintaining Potassium homeostasis.
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Potassium Intake modulates the thiazide-sensitive sodium-chloride cotransporter (NCC) activity via the Kir4.1 Potassium channel.
Kidney International, 2018Co-Authors: Ming Xiao Wang, Xiao-tong Su, James A. Mccormick, Catherina A. Cuevas, Chao Ling Yang, Wenhui Wang, Peng Wu, David H. EllisonAbstract:Kir4.1 in the distal convoluted tubule plays a key role in sensing plasma Potassium and in modulating the thiazide-sensitive sodium-chloride cotransporter (NCC). Here we tested whether dietary Potassium Intake modulates Kir4.1 and whether this is essential for mediating the effect of Potassium diet on NCC. High Potassium Intake inhibited the basolateral 40 pS Potassium channel (a Kir4.1/5.1 heterotetramer) in the distal convoluted tubule, decreased basolateral Potassium conductance, and depolarized the distal convoluted tubule membrane in Kcnj10flox/flox mice, herein referred to as control mice. In contrast, low Potassium Intake activated Kir4.1, increased Potassium currents, and hyperpolarized the distal convoluted tubule membrane. These effects of dietary Potassium Intake on the basolateral Potassium conductance and membrane potential in the distal convoluted tubule were completely absent in inducible kidney-specific Kir4.1 knockout mice. Furthermore, High Potassium Intake decreased, whereas low Potassium Intake increased the abundance of NCC expression only in the control but not in kidney-specific Kir4.1 knockout mice. Renal clearance studies demonstrated that low Potassium augmented, while High Potassium diminished, hydrochlorothiazide-induced natriuresis in control mice. Disruption of Kir4.1 significantly increased basal urinary sodium excretion but it abolished the natriuretic effect of hydrochlorothiazide. Finally, hypokalemia and metabolic alkalosis in kidney-specific Kir4.1 knockout mice were exacerbated by Potassium restriction and only partially corrected by a High-Potassium diet. Thus, Kir4.1 plays an essential role in mediating the effect of dietary Potassium Intake on NCC activity and Potassium homeostasis.
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microrna 802 stimulates romk channels by suppressing caveolin 1
Journal of The American Society of Nephrology, 2011Co-Authors: Wenhui WangAbstract:Dietary Potassium stimulates the surface expression of ROMK channels in the aldosterone-sensitive distal nephron, but the mechanism by which this occurs is incompletely understood. Here, a HighPotassium diet increased the transcription of microRNA (miR) 802 in the cortical collecting duct in mice. In addition, High-Potassium Intake decreased the expression of caveolin-1, whose 3 untranslated region contains the seed sequence of miR-802. In vitro, expression of miR-802 suppressed the expression of caveolin-1, and conversely, downregulation of endogenous miR-802 increased the expression of caveolin-1. Sucrose-gradient centrifugation suggested that caveolin-1 closely associated with ROMK channels, and immunoprecipitation showed that caveolin-1 interacted with the N terminus of ROMK. Expression of caveolin-1 varied inversely with the expression of ROMK1 in the plasma membrane, and caveolin-1 inhibited ROMK1 channel activity. Removal of the clathrin-dependent endocytosis motif from ROMK1 failed to abolish the effect of caveolin-1 on ROMK1 channel activity. Last, expression of miR-802 increased ROMK1 channel activity, an effect blocked by coexpression of caveolin-1. Taken together, miR-802 mediates the stimulatory effect of a High-Potassium diet on ROMK channel activity by suppressing caveolin-1 expression, which leads to increased surface expression of ROMK channels in the distal nephron.
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High Potassium Intake enhances the inhibitory effect of 11 12 eet on enac
Journal of The American Society of Nephrology, 2010Co-Authors: Peng Sun, Daohong Lin, Peng Yue, Houli Jiang, Katherine H Gotlinger, Michal L Schwartzman, John R Falck, Mohan Goli, Wenhui WangAbstract:High dietary Potassium stimulates the renal expression of cytochrome P450 (CYP) epoxygenase 2C23, which metabolizes arachidonic acid (AA). Because the AA metabolite 11,12-epoxyeicosatrienoic acid (11,12-EET) can inhibit the epithelial sodium channel (ENaC) in the cortical collecting duct, we tested whether dietary Potassium modulates ENaC function. High dietary Potassium increased 11,12-EET in the isolated cortical collecting duct, an effect mimicked by inhibiting the angiotensin II type I receptor with valsartan. In patch-clamp experiments, a High Potassium Intake or treatment with valsartan enhanced AA-induced inhibition of ENaC, an effect mediated by a CYP-epoxygenase–dependent pathway. Moreover, High dietary Potassium and valsartan each augmented the inhibitory effect of 11,12-EET on ENaC. Liquid chromatography/mass spectrometry showed that the rate of EET conversion to dihydroxyeicosatrienoic acids (DHET) was lower in renal tissue obtained from rats on a High-Potassium diet than from those on a control diet, but this was not a result of altered expression of soluble epoxide hydrolase (sEH). Instead, suppression of sEH activity seemed to be responsible for the 11,12-EET–mediated enhanced inhibition of ENaC in animals on a High-Potassium diet. Patch-clamp experiments demonstrated that 11,12-DHET was a weak inhibitor of ENaC compared with 11,12-EET, whereas 8,9- and 14,15-DHET were not. Furthermore, inhibition of sEH enhanced the 11,12-EET–induced inhibition of ENaC similar to High dietary Potassium. In conclusion, High dietary Potassium enhances the inhibitory effect of AA and 11,12-EET on ENaC by increasing CYP epoxygenase activity and decreasing sEH activity, respectively.
Nikolaos E. Rodopaios - One of the best experts on this subject based on the ideXlab platform.
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Sodium and Potassium Intake in Healthy Adults in Thessaloniki Greater Metropolitan Area—The Salt Intake in Northern Greece (SING) Study
Nutrients, 2017Co-Authors: Eleni Vasara, Georgios Marakis, João Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos E. Rodopaios, Alexandra A. Koulouri, Francesco P. CappuccioAbstract:A reduction in population sodium (as salt) consumption is a global health priority, as well as one of the most cost-effective strategies to reduce the burden of cardiovascular disease. High Potassium Intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and Potassium Intake. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and Potassium Intakes in a sample of healthy adults in northern Greece, and to determine whether adherence to a Mediterranean diet is related to different sodium Intakes or sodium-to-Potassium ratio. A cross-sectional survey was carried out in the Thessaloniki greater metropolitan area (northern Greece) (n = 252, aged 18–75 years, 45.2% males). Participants’ dietary sodium and Potassium Intakes were determined by 24-hour urinary sodium and Potassium excretions. In addition, we estimated their adherence to Mediterranean diet by the use of an 11-item MedDietScore (range 0–55). The mean sodium excretion was 175 (SD 72) mmol/day, equivalent to 4220 (1745) mg of sodium or 10.7 (4.4) g of salt per day, and the Potassium excretion was 65 (25) mmol/day, equivalent to 3303 (1247) mg per day. Men had Higher sodium and Potassium excretions compared to women. Only 5.6% of the sample had salt Intake
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sodium and Potassium Intake in healthy adults in thessaloniki greater metropolitan area the salt Intake in northern greece sing study
Nutrients, 2017Co-Authors: Eleni Vasara, Georgios Marakis, João Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos E. Rodopaios, Alexandra A. Koulouri, Francesco P. CappuccioAbstract:A reduction in population sodium (as salt) consumption is a global health priority, as well as one of the most cost-effective strategies to reduce the burden of cardiovascular disease. High Potassium Intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and Potassium Intake. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and Potassium Intakes in a sample of healthy adults in northern Greece, and to determine whether adherence to a Mediterranean diet is related to different sodium Intakes or sodium-to-Potassium ratio. A cross-sectional survey was carried out in the Thessaloniki greater metropolitan area (northern Greece) (n = 252, aged 18–75 years, 45.2% males). Participants’ dietary sodium and Potassium Intakes were determined by 24-hour urinary sodium and Potassium excretions. In addition, we estimated their adherence to Mediterranean diet by the use of an 11-item MedDietScore (range 0–55). The mean sodium excretion was 175 (SD 72) mmol/day, equivalent to 4220 (1745) mg of sodium or 10.7 (4.4) g of salt per day, and the Potassium excretion was 65 (25) mmol/day, equivalent to 3303 (1247) mg per day. Men had Higher sodium and Potassium excretions compared to women. Only 5.6% of the sample had salt Intake <5 g/day, which is the target Intake recommended by the World Health Organization. Mean sodium-to-Potassium excretion ratio was 2.82 (1.07). There was no significant difference in salt or Potassium Intake or their ratio across MedDietScore quartiles. No significant relationships were found between salt Intake and adherence to a Mediterranean diet, suggesting that the perception of the health benefits of the Mediterranean diet does not hold when referring to salt consumption. These results suggest the need for a larger, nation-wide survey on salt Intake in Greece and underline the importance of continuation of salt reduction initiatives in Greece.
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Sodium and Potassium Intake in Healthy Adults in Thessaloniki Greater Metropolitan Area—The SING (Salt Intake in Northern Greece) Study
2017Co-Authors: Eleni Vasara, Georgios Marakis, João Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos E. Rodopaios, Alexandra A. Koulouri, Francesco P. CappuccioAbstract:A reduction in population sodium (as salt) consumption is one of the most cost-effective strategies to reduce the burden of cardiovascular disease and it is a global health priority. High Potassium Intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and Potassium Intakes. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and Potassium Intakes in a sample of healthy adults in northern Greece and to determine whether adherence to a Mediterranean diet is related to different sodium Intakes or sodium-to-Potassium ratio. A cross-sectional survey was carried out in Thessaloniki greater metropolitan area (northern Greece) (n=252, aged 18-75 years, 45.2% males). Participants’ dietary sodium and Potassium Intakes were determined by 24h urinary sodium and Potassium excretions. In addition, we estimated their adherence to Mediterranean diet by the use of an 11-item MedDietScore (range 0-55). The mean sodium excretion was 175 (SD 72) mmol/day, equivalent to 4,220 (1,745) mg of sodium or 10.7 (4.4) g of salt per day and Potassium excretion was 65 (25) mmol/day, equivalent to 3,303 (1,247) mg/day. Men had Higher sodium and Potassium excretions compared to women. Only 5.6% of the sample had salt Intake <5g/d, which is the target Intake recommended by the WHO. Mean sodium-to-Potassium Intake ratio was 1.34 (0.51). There was no significant difference in salt or Potassium Intake or their ratio across MedDietScore quartiles. No significant relationships were found between salt Intake and adherence to Mediterranean diet, suggesting that the perception of the health benefits of the Mediterranean diet does not hold when referring to salt consumption. These results suggest the need for a larger nation-wide survey on salt Intake in Greece and underline the importance of continuation of salt reduction initiatives in Greece.
João Breda - One of the best experts on this subject based on the ideXlab platform.
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Sodium and Potassium Intake in Healthy Adults in Thessaloniki Greater Metropolitan Area—The Salt Intake in Northern Greece (SING) Study
Nutrients, 2017Co-Authors: Eleni Vasara, Georgios Marakis, João Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos E. Rodopaios, Alexandra A. Koulouri, Francesco P. CappuccioAbstract:A reduction in population sodium (as salt) consumption is a global health priority, as well as one of the most cost-effective strategies to reduce the burden of cardiovascular disease. High Potassium Intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and Potassium Intake. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and Potassium Intakes in a sample of healthy adults in northern Greece, and to determine whether adherence to a Mediterranean diet is related to different sodium Intakes or sodium-to-Potassium ratio. A cross-sectional survey was carried out in the Thessaloniki greater metropolitan area (northern Greece) (n = 252, aged 18–75 years, 45.2% males). Participants’ dietary sodium and Potassium Intakes were determined by 24-hour urinary sodium and Potassium excretions. In addition, we estimated their adherence to Mediterranean diet by the use of an 11-item MedDietScore (range 0–55). The mean sodium excretion was 175 (SD 72) mmol/day, equivalent to 4220 (1745) mg of sodium or 10.7 (4.4) g of salt per day, and the Potassium excretion was 65 (25) mmol/day, equivalent to 3303 (1247) mg per day. Men had Higher sodium and Potassium excretions compared to women. Only 5.6% of the sample had salt Intake
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sodium and Potassium Intake in healthy adults in thessaloniki greater metropolitan area the salt Intake in northern greece sing study
Nutrients, 2017Co-Authors: Eleni Vasara, Georgios Marakis, João Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos E. Rodopaios, Alexandra A. Koulouri, Francesco P. CappuccioAbstract:A reduction in population sodium (as salt) consumption is a global health priority, as well as one of the most cost-effective strategies to reduce the burden of cardiovascular disease. High Potassium Intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and Potassium Intake. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and Potassium Intakes in a sample of healthy adults in northern Greece, and to determine whether adherence to a Mediterranean diet is related to different sodium Intakes or sodium-to-Potassium ratio. A cross-sectional survey was carried out in the Thessaloniki greater metropolitan area (northern Greece) (n = 252, aged 18–75 years, 45.2% males). Participants’ dietary sodium and Potassium Intakes were determined by 24-hour urinary sodium and Potassium excretions. In addition, we estimated their adherence to Mediterranean diet by the use of an 11-item MedDietScore (range 0–55). The mean sodium excretion was 175 (SD 72) mmol/day, equivalent to 4220 (1745) mg of sodium or 10.7 (4.4) g of salt per day, and the Potassium excretion was 65 (25) mmol/day, equivalent to 3303 (1247) mg per day. Men had Higher sodium and Potassium excretions compared to women. Only 5.6% of the sample had salt Intake <5 g/day, which is the target Intake recommended by the World Health Organization. Mean sodium-to-Potassium excretion ratio was 2.82 (1.07). There was no significant difference in salt or Potassium Intake or their ratio across MedDietScore quartiles. No significant relationships were found between salt Intake and adherence to a Mediterranean diet, suggesting that the perception of the health benefits of the Mediterranean diet does not hold when referring to salt consumption. These results suggest the need for a larger, nation-wide survey on salt Intake in Greece and underline the importance of continuation of salt reduction initiatives in Greece.
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Sodium and Potassium Intake in Healthy Adults in Thessaloniki Greater Metropolitan Area—The SING (Salt Intake in Northern Greece) Study
2017Co-Authors: Eleni Vasara, Georgios Marakis, João Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos E. Rodopaios, Alexandra A. Koulouri, Francesco P. CappuccioAbstract:A reduction in population sodium (as salt) consumption is one of the most cost-effective strategies to reduce the burden of cardiovascular disease and it is a global health priority. High Potassium Intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and Potassium Intakes. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and Potassium Intakes in a sample of healthy adults in northern Greece and to determine whether adherence to a Mediterranean diet is related to different sodium Intakes or sodium-to-Potassium ratio. A cross-sectional survey was carried out in Thessaloniki greater metropolitan area (northern Greece) (n=252, aged 18-75 years, 45.2% males). Participants’ dietary sodium and Potassium Intakes were determined by 24h urinary sodium and Potassium excretions. In addition, we estimated their adherence to Mediterranean diet by the use of an 11-item MedDietScore (range 0-55). The mean sodium excretion was 175 (SD 72) mmol/day, equivalent to 4,220 (1,745) mg of sodium or 10.7 (4.4) g of salt per day and Potassium excretion was 65 (25) mmol/day, equivalent to 3,303 (1,247) mg/day. Men had Higher sodium and Potassium excretions compared to women. Only 5.6% of the sample had salt Intake <5g/d, which is the target Intake recommended by the WHO. Mean sodium-to-Potassium Intake ratio was 1.34 (0.51). There was no significant difference in salt or Potassium Intake or their ratio across MedDietScore quartiles. No significant relationships were found between salt Intake and adherence to Mediterranean diet, suggesting that the perception of the health benefits of the Mediterranean diet does not hold when referring to salt consumption. These results suggest the need for a larger nation-wide survey on salt Intake in Greece and underline the importance of continuation of salt reduction initiatives in Greece.