The Experts below are selected from a list of 24 Experts worldwide ranked by ideXlab platform

A Romano - One of the best experts on this subject based on the ideXlab platform.

  • The increased Histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by specific IgE.
    Allergy, 2002
    Co-Authors: Rosa-maria Rodriguez, J-l Guéant, I Aimone-gastin, P Gérard, F Amoghly, A Bellou, Y Jullière, G Faure, N Danchin, A Romano
    Abstract:

    Background:  The release of Histamine by iodinated contrast media (ICM) is higher in coronary artery disease patients than in noncoronary patients during coronary angiogram. Methods:  Eighty-eight patients who underwent a coronary angiography were classified either as having coronary artery disease or as noncoronary patients. Histamine concentration was higher than the 6.8 nM upper limit in 7 cases (group 1), of whom six were coronary artery disease patients. We compared the IgE and complement fractions in plasma of these patients to two control groups with normal Histamine Blood Level, one (group 2) with and the other (group 3) without coronary artery disease. Results:  No difference of total IgE and C 3c and C 4 complement fractions was found among the three groups. Anti-ioxaglate IgE-RIA was positive in only one patient from group 1. The affinity of drug-IgE binding in the serum of this patient was very low (Kd: 18.7 mM). The Level of anti-ICM IgE detected by ioxitalamate- and iomeprol-Sepharose RIA was significantly higher in groups 2 and 3 than in group 1. Conclusions:  The higher Histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by IgE or complement activation. Further studies are needed to investigate the implication of Histamine release factors.

  • The increased Histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by specific IgE.
    Allergy, 2002
    Co-Authors: Rosa-maria Rodriguez, J-l Guéant, I Aimone-gastin, P Gérard, F Amoghly, A Bellou, Y Jullière, G Faure, N Danchin, A Romano
    Abstract:

    The release of Histamine by iodinated contrast media (ICM) is higher in coronary artery disease patients than in noncoronary patients during coronary angiogram. Eighty-eight patients who underwent a coronary angiography were classified either as having coronary artery disease or as noncoronary patients. Histamine concentration was higher than the 6.8 nM upper limit in 7 cases (group 1), of whom six were coronary artery disease patients. We compared the IgE and complement fractions in plasma of these patients to two control groups with normal Histamine Blood Level, one (group 2) with and the other (group 3) without coronary artery disease. No difference of total IgE and C(3c) and C(4) complement fractions was found among the three groups. Anti-ioxaglate IgE-RIA was positive in only one patient from group 1. The affinity of drug-IgE binding in the serum of this patient was very low (Kd: 18.7 mM). The Level of anti-ICM IgE detected by ioxitalamate- and iomeprol-Sepharose RIA was significantly higher in groups 2 and 3 than in group 1. The higher Histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by IgE or complement activation. Further studies are needed to investigate the implication of Histamine release factors.

Javid Fereidoni - One of the best experts on this subject based on the ideXlab platform.

  • effect of hyperthermia on Histamine Blood Level and convulsive behavior in infant rats
    Epilepsy & Behavior, 2013
    Co-Authors: Peyman Gholipoor, Ehsan Saboory, Shiva Roshanmilani, Javid Fereidoni
    Abstract:

    Febrile seizures (FS), which have been extensively studied using animal models, are the most common type of convulsive events in children, but the cellular mechanisms causing FS are still unclear. Histamine has been suggested to participate in seizure control. This study investigated the effect of hyperthermia (HT) on Histamine Blood Level (HBL) and convulsive behavior in prepubertal rats. Forty Wistar rat pups were assigned to 5 groups (n=8), namely, control, HT, cromolyn, chlorpheniramine, and ranitidine. Two groups of adult rats were also used as control and HT adults. The control rats were placed in a hyperthermic chamber, and a room temperature current of air was blown on them. In all other groups, the rats were placed in the chamber for 30 min, and a current of warm air was applied to them. In the pretreatment groups, the rats received an injection of 68-mg/kg cromolyn sodium, 4-mg/kg chlorpheniramine, or 80-mg/kg ranitidine intraperitoneally 30 min prior to HT. Body temperature and convulsive behaviors were recorded. Then, the rats were anesthetized with ether, and their Blood sample was obtained through direct heart puncture. Hyperthermia initiated convulsive behaviors in infant rats but not in the adult ones. Pretreatment with chlorpheniramine significantly potentiated convulsive behaviors (p=0.017). Hyperthermia led to a significant decrease in the HBL of both infant (p<0.001) and adult (p=0.003) rats. Pretreatments led to more decrease in the HBL of infant rats (p<0.001). It was concluded that HT could lead to a decrease in HBL, which in turn increases the seizure susceptibility of animals. Histamine may have a pivotal role in hyperthermia-induced seizures.

  • Effect of hyperthermia on Histamine Blood Level and convulsive behavior in infant rats
    Epilepsy & behavior : E&B, 2013
    Co-Authors: Peyman Gholipoor, Ehsan Saboory, Shiva Roshan-milani, Javid Fereidoni
    Abstract:

    Febrile seizures (FS), which have been extensively studied using animal models, are the most common type of convulsive events in children, but the cellular mechanisms causing FS are still unclear. Histamine has been suggested to participate in seizure control. This study investigated the effect of hyperthermia (HT) on Histamine Blood Level (HBL) and convulsive behavior in prepubertal rats. Forty Wistar rat pups were assigned to 5 groups (n=8), namely, control, HT, cromolyn, chlorpheniramine, and ranitidine. Two groups of adult rats were also used as control and HT adults. The control rats were placed in a hyperthermic chamber, and a room temperature current of air was blown on them. In all other groups, the rats were placed in the chamber for 30 min, and a current of warm air was applied to them. In the pretreatment groups, the rats received an injection of 68-mg/kg cromolyn sodium, 4-mg/kg chlorpheniramine, or 80-mg/kg ranitidine intraperitoneally 30 min prior to HT. Body temperature and convulsive behaviors were recorded. Then, the rats were anesthetized with ether, and their Blood sample was obtained through direct heart puncture. Hyperthermia initiated convulsive behaviors in infant rats but not in the adult ones. Pretreatment with chlorpheniramine significantly potentiated convulsive behaviors (p=0.017). Hyperthermia led to a significant decrease in the HBL of both infant (p

Rosa-maria Rodriguez - One of the best experts on this subject based on the ideXlab platform.

  • The increased Histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by specific IgE.
    Allergy, 2002
    Co-Authors: Rosa-maria Rodriguez, J-l Guéant, I Aimone-gastin, P Gérard, F Amoghly, A Bellou, Y Jullière, G Faure, N Danchin, A Romano
    Abstract:

    Background:  The release of Histamine by iodinated contrast media (ICM) is higher in coronary artery disease patients than in noncoronary patients during coronary angiogram. Methods:  Eighty-eight patients who underwent a coronary angiography were classified either as having coronary artery disease or as noncoronary patients. Histamine concentration was higher than the 6.8 nM upper limit in 7 cases (group 1), of whom six were coronary artery disease patients. We compared the IgE and complement fractions in plasma of these patients to two control groups with normal Histamine Blood Level, one (group 2) with and the other (group 3) without coronary artery disease. Results:  No difference of total IgE and C 3c and C 4 complement fractions was found among the three groups. Anti-ioxaglate IgE-RIA was positive in only one patient from group 1. The affinity of drug-IgE binding in the serum of this patient was very low (Kd: 18.7 mM). The Level of anti-ICM IgE detected by ioxitalamate- and iomeprol-Sepharose RIA was significantly higher in groups 2 and 3 than in group 1. Conclusions:  The higher Histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by IgE or complement activation. Further studies are needed to investigate the implication of Histamine release factors.

  • The increased Histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by specific IgE.
    Allergy, 2002
    Co-Authors: Rosa-maria Rodriguez, J-l Guéant, I Aimone-gastin, P Gérard, F Amoghly, A Bellou, Y Jullière, G Faure, N Danchin, A Romano
    Abstract:

    The release of Histamine by iodinated contrast media (ICM) is higher in coronary artery disease patients than in noncoronary patients during coronary angiogram. Eighty-eight patients who underwent a coronary angiography were classified either as having coronary artery disease or as noncoronary patients. Histamine concentration was higher than the 6.8 nM upper limit in 7 cases (group 1), of whom six were coronary artery disease patients. We compared the IgE and complement fractions in plasma of these patients to two control groups with normal Histamine Blood Level, one (group 2) with and the other (group 3) without coronary artery disease. No difference of total IgE and C(3c) and C(4) complement fractions was found among the three groups. Anti-ioxaglate IgE-RIA was positive in only one patient from group 1. The affinity of drug-IgE binding in the serum of this patient was very low (Kd: 18.7 mM). The Level of anti-ICM IgE detected by ioxitalamate- and iomeprol-Sepharose RIA was significantly higher in groups 2 and 3 than in group 1. The higher Histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by IgE or complement activation. Further studies are needed to investigate the implication of Histamine release factors.

Peyman Gholipoor - One of the best experts on this subject based on the ideXlab platform.

  • effect of hyperthermia on Histamine Blood Level and convulsive behavior in infant rats
    Epilepsy & Behavior, 2013
    Co-Authors: Peyman Gholipoor, Ehsan Saboory, Shiva Roshanmilani, Javid Fereidoni
    Abstract:

    Febrile seizures (FS), which have been extensively studied using animal models, are the most common type of convulsive events in children, but the cellular mechanisms causing FS are still unclear. Histamine has been suggested to participate in seizure control. This study investigated the effect of hyperthermia (HT) on Histamine Blood Level (HBL) and convulsive behavior in prepubertal rats. Forty Wistar rat pups were assigned to 5 groups (n=8), namely, control, HT, cromolyn, chlorpheniramine, and ranitidine. Two groups of adult rats were also used as control and HT adults. The control rats were placed in a hyperthermic chamber, and a room temperature current of air was blown on them. In all other groups, the rats were placed in the chamber for 30 min, and a current of warm air was applied to them. In the pretreatment groups, the rats received an injection of 68-mg/kg cromolyn sodium, 4-mg/kg chlorpheniramine, or 80-mg/kg ranitidine intraperitoneally 30 min prior to HT. Body temperature and convulsive behaviors were recorded. Then, the rats were anesthetized with ether, and their Blood sample was obtained through direct heart puncture. Hyperthermia initiated convulsive behaviors in infant rats but not in the adult ones. Pretreatment with chlorpheniramine significantly potentiated convulsive behaviors (p=0.017). Hyperthermia led to a significant decrease in the HBL of both infant (p<0.001) and adult (p=0.003) rats. Pretreatments led to more decrease in the HBL of infant rats (p<0.001). It was concluded that HT could lead to a decrease in HBL, which in turn increases the seizure susceptibility of animals. Histamine may have a pivotal role in hyperthermia-induced seizures.

  • Effect of hyperthermia on Histamine Blood Level and convulsive behavior in infant rats
    Epilepsy & behavior : E&B, 2013
    Co-Authors: Peyman Gholipoor, Ehsan Saboory, Shiva Roshan-milani, Javid Fereidoni
    Abstract:

    Febrile seizures (FS), which have been extensively studied using animal models, are the most common type of convulsive events in children, but the cellular mechanisms causing FS are still unclear. Histamine has been suggested to participate in seizure control. This study investigated the effect of hyperthermia (HT) on Histamine Blood Level (HBL) and convulsive behavior in prepubertal rats. Forty Wistar rat pups were assigned to 5 groups (n=8), namely, control, HT, cromolyn, chlorpheniramine, and ranitidine. Two groups of adult rats were also used as control and HT adults. The control rats were placed in a hyperthermic chamber, and a room temperature current of air was blown on them. In all other groups, the rats were placed in the chamber for 30 min, and a current of warm air was applied to them. In the pretreatment groups, the rats received an injection of 68-mg/kg cromolyn sodium, 4-mg/kg chlorpheniramine, or 80-mg/kg ranitidine intraperitoneally 30 min prior to HT. Body temperature and convulsive behaviors were recorded. Then, the rats were anesthetized with ether, and their Blood sample was obtained through direct heart puncture. Hyperthermia initiated convulsive behaviors in infant rats but not in the adult ones. Pretreatment with chlorpheniramine significantly potentiated convulsive behaviors (p=0.017). Hyperthermia led to a significant decrease in the HBL of both infant (p

N Danchin - One of the best experts on this subject based on the ideXlab platform.

  • The increased Histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by specific IgE.
    Allergy, 2002
    Co-Authors: Rosa-maria Rodriguez, J-l Guéant, I Aimone-gastin, P Gérard, F Amoghly, A Bellou, Y Jullière, G Faure, N Danchin, A Romano
    Abstract:

    Background:  The release of Histamine by iodinated contrast media (ICM) is higher in coronary artery disease patients than in noncoronary patients during coronary angiogram. Methods:  Eighty-eight patients who underwent a coronary angiography were classified either as having coronary artery disease or as noncoronary patients. Histamine concentration was higher than the 6.8 nM upper limit in 7 cases (group 1), of whom six were coronary artery disease patients. We compared the IgE and complement fractions in plasma of these patients to two control groups with normal Histamine Blood Level, one (group 2) with and the other (group 3) without coronary artery disease. Results:  No difference of total IgE and C 3c and C 4 complement fractions was found among the three groups. Anti-ioxaglate IgE-RIA was positive in only one patient from group 1. The affinity of drug-IgE binding in the serum of this patient was very low (Kd: 18.7 mM). The Level of anti-ICM IgE detected by ioxitalamate- and iomeprol-Sepharose RIA was significantly higher in groups 2 and 3 than in group 1. Conclusions:  The higher Histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by IgE or complement activation. Further studies are needed to investigate the implication of Histamine release factors.

  • The increased Histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by specific IgE.
    Allergy, 2002
    Co-Authors: Rosa-maria Rodriguez, J-l Guéant, I Aimone-gastin, P Gérard, F Amoghly, A Bellou, Y Jullière, G Faure, N Danchin, A Romano
    Abstract:

    The release of Histamine by iodinated contrast media (ICM) is higher in coronary artery disease patients than in noncoronary patients during coronary angiogram. Eighty-eight patients who underwent a coronary angiography were classified either as having coronary artery disease or as noncoronary patients. Histamine concentration was higher than the 6.8 nM upper limit in 7 cases (group 1), of whom six were coronary artery disease patients. We compared the IgE and complement fractions in plasma of these patients to two control groups with normal Histamine Blood Level, one (group 2) with and the other (group 3) without coronary artery disease. No difference of total IgE and C(3c) and C(4) complement fractions was found among the three groups. Anti-ioxaglate IgE-RIA was positive in only one patient from group 1. The affinity of drug-IgE binding in the serum of this patient was very low (Kd: 18.7 mM). The Level of anti-ICM IgE detected by ioxitalamate- and iomeprol-Sepharose RIA was significantly higher in groups 2 and 3 than in group 1. The higher Histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by IgE or complement activation. Further studies are needed to investigate the implication of Histamine release factors.