The Experts below are selected from a list of 264 Experts worldwide ranked by ideXlab platform
Hiroshi Tamai - One of the best experts on this subject based on the ideXlab platform.
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Lamotrigine for intractable migraine-like headaches in Sturge–Weber syndrome
Brain & Development, 2013Co-Authors: Shohei Nomura, Takuya Tanabe, Shuichi Shimakawa, Miho Fukui, Hiroshi TamaiAbstract:Abstract We herein report that naratriptan remarkably improved intractable migraine-like headaches in a patient with Sturge–Weber syndrome (SWS) despite his past history of cerebral infarction. In addition, lamotrigine had a prophylactic effect on his visual aura and headaches. An 18-year-old male patient with SWS had intractable migraine-like headaches every several months from the age of 3 years. His migraine-like headaches were characterized by pulsating attacks preceded by left Homonymous Hemianopsia, which persisted after headache disappearance. In addition, after 14 years of age, the pulsating headaches were preceded by photophobia without Homonymous Hemianopsia and occurred almost daily. Headache pains were not improved by acetaminophen or loxoprofen sodium hydrate. Furthermore, various prophylactic drugs were ineffective. After obtaining informed consent, naratriptan was administered. The pain severity was reduced and the duration of headache with Homonymous Hemianopsia was shortened from several days to several hours. Interestingly, naratriptan also shortened the duration of Homonymous Hemianopsia to several hours. We confirmed that his headache attacks were not epileptic seizures by ictal electroencephalography. However, 25 mg/day of lamotrigine had a prophylactic effect on the frequency of headache. Moreover, lamotrigine led to complete remission of his headache without Homonymous Hemianopsia. Lamotrigine may have an advantage in terms of reducing the risk of cerebrovascular disease caused by migraine-like headaches and the use of triptans. The most effective management for migraine-like headaches in patients with SWS has not been established. Lamotrigine is a potentially effective option for patients with SWS with migraine-like headaches.
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prolonged left Homonymous Hemianopsia associated with migraine like attacks in a child with sturge weber syndrome
Brain & Development, 2010Co-Authors: Shuichi Shimakawa, Ryohei Miyamoto, Takuya Tanabe, Hiroshi TamaiAbstract:We report a patient with Sturge-Weber Syndrome (SWS) who developed migraine-like headaches followed by cerebral infarction. SWS without facial nevus was diagnosed based on calcification detected by CT and pial angioma detected by enhanced MRI. His migraine-like headaches were preceded by left Homonymous Hemianopsia, which persisted for more than 60 min. Although Homonymous Hemianopsia disappeared with cessation of the headache until 13 years of age, from age 14 years onward, this Homonymous Hemianopsia persisted after the headaches ended. Moreover, reduced cerebral blood flow was seen in the right occipital area on SPECT. At first, his left Homonymous Hemianopsia persisted for several months after the headache disappeared, but it had recovered completely. However, the durations of episodes of left Homonymous Hemianopsia, which persisted after headache disappearance, gradually became longer. At last one year after his first admission, the visual defect had become permanent. SWS is well known to be associated with migraine attacks and Hemianopsia. However, the course of our present patient, i.e. recurrent Homonymous Hemianopsia, associated with migraine-like headaches becoming permanent, is rare. The pathophysiological mechanism underlying this clinical course is uncertain. The efficacy of valproate and propranolol as preventive therapy has been inadequate, to date.
Lance E Trexler - One of the best experts on this subject based on the ideXlab platform.
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volitional control of Homonymous Hemianopsia a single case study
Neuropsychologia, 1998Co-Authors: Lance E TrexlerAbstract:Abstract A 52-year-old woman suffered a posterior left hemisphere infarction involving the geniculo-striate system with right Homonymous Hemianopsia. Eighteen months after the stroke, we used perimetry and PET imaging of cerebral blood flow to demonstrate the patient’s volitional control over the size of the scotoma. The volitional control could be eliminated with competing cognitive tasks. Significant increases in cerebral blood flow in contralateral medial prefrontal cortex, and in ipsilateral dorsolateral frontal convexity, temporoparietal and insular cortex were associated with volitional control of the visual field defect.
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volitional control of Homonymous Hemianopsia a single case study
Neuropsychologia, 1998Co-Authors: Lance E TrexlerAbstract:Abstract A 52-year-old woman suffered a posterior left hemisphere infarction involving the geniculo-striate system with right Homonymous Hemianopsia. Eighteen months after the stroke, we used perimetry and PET imaging of cerebral blood flow to demonstrate the patient’s volitional control over the size of the scotoma. The volitional control could be eliminated with competing cognitive tasks. Significant increases in cerebral blood flow in contralateral medial prefrontal cortex, and in ipsilateral dorsolateral frontal convexity, temporoparietal and insular cortex were associated with volitional control of the visual field defect.
Shuichi Shimakawa - One of the best experts on this subject based on the ideXlab platform.
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Lamotrigine for intractable migraine-like headaches in Sturge–Weber syndrome
Brain & Development, 2013Co-Authors: Shohei Nomura, Takuya Tanabe, Shuichi Shimakawa, Miho Fukui, Hiroshi TamaiAbstract:Abstract We herein report that naratriptan remarkably improved intractable migraine-like headaches in a patient with Sturge–Weber syndrome (SWS) despite his past history of cerebral infarction. In addition, lamotrigine had a prophylactic effect on his visual aura and headaches. An 18-year-old male patient with SWS had intractable migraine-like headaches every several months from the age of 3 years. His migraine-like headaches were characterized by pulsating attacks preceded by left Homonymous Hemianopsia, which persisted after headache disappearance. In addition, after 14 years of age, the pulsating headaches were preceded by photophobia without Homonymous Hemianopsia and occurred almost daily. Headache pains were not improved by acetaminophen or loxoprofen sodium hydrate. Furthermore, various prophylactic drugs were ineffective. After obtaining informed consent, naratriptan was administered. The pain severity was reduced and the duration of headache with Homonymous Hemianopsia was shortened from several days to several hours. Interestingly, naratriptan also shortened the duration of Homonymous Hemianopsia to several hours. We confirmed that his headache attacks were not epileptic seizures by ictal electroencephalography. However, 25 mg/day of lamotrigine had a prophylactic effect on the frequency of headache. Moreover, lamotrigine led to complete remission of his headache without Homonymous Hemianopsia. Lamotrigine may have an advantage in terms of reducing the risk of cerebrovascular disease caused by migraine-like headaches and the use of triptans. The most effective management for migraine-like headaches in patients with SWS has not been established. Lamotrigine is a potentially effective option for patients with SWS with migraine-like headaches.
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prolonged left Homonymous Hemianopsia associated with migraine like attacks in a child with sturge weber syndrome
Brain & Development, 2010Co-Authors: Shuichi Shimakawa, Ryohei Miyamoto, Takuya Tanabe, Hiroshi TamaiAbstract:We report a patient with Sturge-Weber Syndrome (SWS) who developed migraine-like headaches followed by cerebral infarction. SWS without facial nevus was diagnosed based on calcification detected by CT and pial angioma detected by enhanced MRI. His migraine-like headaches were preceded by left Homonymous Hemianopsia, which persisted for more than 60 min. Although Homonymous Hemianopsia disappeared with cessation of the headache until 13 years of age, from age 14 years onward, this Homonymous Hemianopsia persisted after the headaches ended. Moreover, reduced cerebral blood flow was seen in the right occipital area on SPECT. At first, his left Homonymous Hemianopsia persisted for several months after the headache disappeared, but it had recovered completely. However, the durations of episodes of left Homonymous Hemianopsia, which persisted after headache disappearance, gradually became longer. At last one year after his first admission, the visual defect had become permanent. SWS is well known to be associated with migraine attacks and Hemianopsia. However, the course of our present patient, i.e. recurrent Homonymous Hemianopsia, associated with migraine-like headaches becoming permanent, is rare. The pathophysiological mechanism underlying this clinical course is uncertain. The efficacy of valproate and propranolol as preventive therapy has been inadequate, to date.
Mineo Takagi - One of the best experts on this subject based on the ideXlab platform.
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functional magnetic resonance imaging in Homonymous Hemianopsia
American Journal of Ophthalmology, 1996Co-Authors: Atsushi Miki, Takashi Nakajima, Motoi Fujita, Mineo TakagiAbstract:Purpose We performed functional magnetic resonance imaging associated with brain activity to evaluate the abnormality of the visual pathway in hemianoptic patients. Methods We studied five patients with Homonymous Hemianopsia caused by retrochiasmal lesions and five control subjects. On the basis of a blood oxygenation level-dependent contrast mechanism, magnetic resonance imaging was performed with a standard clinical 1.5-tesla system. We evaluated the asymmetrically increased signal intensities in the calcarine cortex during visual stimulation and compared them with the findings of Goldmann perimetry. Results Cortical activations with a marked interhemispheric contrast of the primary visual cortex consistent with the visual field defects were observed in three of the five patients. In two of the patients without macular field preservation in the defective hemifield, functional magnetic resonance imaging showed an absence of response in the primary visual cortex of the affected side. In the patient with superior quadrantanopsia, we could detect clear laterality by selecting the imaging plane inferior to the calcarine fissure. The other two hemianoptic patients with macular sparing showed symmetric responses. Conclusions These findings suggest that functional magnetic resonance imaging is valuable in assessing local brain function in patients with visual deficits; therefore, it is a promising method for the objective detection of abnormalities in the afferent visual system.
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Functional magnetic resonance imaging of the human primary visual cortex during visual stimulation
Japanese Journal of Ophthalmology, 1995Co-Authors: Atsushi Miki, Takashi Nakajima, Motoi Fujita, Mineo Takagi, Watanabe H, Takeo Kuwabara, Naruse S, Haruki AbeAbstract:Signal changes in the human primary visual cortex during visual stimulation were evaluated using non-invasive functional magnetic resonance imaging (fMRI). The experiments were performed on 10 normal human volunteers and 2 patients with Homonymous Hemianopsia, including one who was recovering from the exacerbation of multiple sclerosis. The visual stimuli were provided by a pattern generator using the checkerboard pattern for determining the visual evoked potential of full-field and hemifield stimulation. In normal volunteers, a signal increase was observed on the bilateral primary visual cortex during the full-field stimulation and on the contra-lateral cortex during hemifield stimulation. In the patient with Homonymous Hemianopsia after cerebral infarction, the signal change was clearly decreased on the affected side. In the other patient, the one recovering from multiple sclerosis with an almost normal visual field, the fMRI was within normal limits. These results suggest that it is possible to visualize the activation of the visual cortex during visual stimulation, and that there is a possibility of using this test as an objective method of visual field examination.
Takuya Tanabe - One of the best experts on this subject based on the ideXlab platform.
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Lamotrigine for intractable migraine-like headaches in Sturge–Weber syndrome
Brain & Development, 2013Co-Authors: Shohei Nomura, Takuya Tanabe, Shuichi Shimakawa, Miho Fukui, Hiroshi TamaiAbstract:Abstract We herein report that naratriptan remarkably improved intractable migraine-like headaches in a patient with Sturge–Weber syndrome (SWS) despite his past history of cerebral infarction. In addition, lamotrigine had a prophylactic effect on his visual aura and headaches. An 18-year-old male patient with SWS had intractable migraine-like headaches every several months from the age of 3 years. His migraine-like headaches were characterized by pulsating attacks preceded by left Homonymous Hemianopsia, which persisted after headache disappearance. In addition, after 14 years of age, the pulsating headaches were preceded by photophobia without Homonymous Hemianopsia and occurred almost daily. Headache pains were not improved by acetaminophen or loxoprofen sodium hydrate. Furthermore, various prophylactic drugs were ineffective. After obtaining informed consent, naratriptan was administered. The pain severity was reduced and the duration of headache with Homonymous Hemianopsia was shortened from several days to several hours. Interestingly, naratriptan also shortened the duration of Homonymous Hemianopsia to several hours. We confirmed that his headache attacks were not epileptic seizures by ictal electroencephalography. However, 25 mg/day of lamotrigine had a prophylactic effect on the frequency of headache. Moreover, lamotrigine led to complete remission of his headache without Homonymous Hemianopsia. Lamotrigine may have an advantage in terms of reducing the risk of cerebrovascular disease caused by migraine-like headaches and the use of triptans. The most effective management for migraine-like headaches in patients with SWS has not been established. Lamotrigine is a potentially effective option for patients with SWS with migraine-like headaches.
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prolonged left Homonymous Hemianopsia associated with migraine like attacks in a child with sturge weber syndrome
Brain & Development, 2010Co-Authors: Shuichi Shimakawa, Ryohei Miyamoto, Takuya Tanabe, Hiroshi TamaiAbstract:We report a patient with Sturge-Weber Syndrome (SWS) who developed migraine-like headaches followed by cerebral infarction. SWS without facial nevus was diagnosed based on calcification detected by CT and pial angioma detected by enhanced MRI. His migraine-like headaches were preceded by left Homonymous Hemianopsia, which persisted for more than 60 min. Although Homonymous Hemianopsia disappeared with cessation of the headache until 13 years of age, from age 14 years onward, this Homonymous Hemianopsia persisted after the headaches ended. Moreover, reduced cerebral blood flow was seen in the right occipital area on SPECT. At first, his left Homonymous Hemianopsia persisted for several months after the headache disappeared, but it had recovered completely. However, the durations of episodes of left Homonymous Hemianopsia, which persisted after headache disappearance, gradually became longer. At last one year after his first admission, the visual defect had become permanent. SWS is well known to be associated with migraine attacks and Hemianopsia. However, the course of our present patient, i.e. recurrent Homonymous Hemianopsia, associated with migraine-like headaches becoming permanent, is rare. The pathophysiological mechanism underlying this clinical course is uncertain. The efficacy of valproate and propranolol as preventive therapy has been inadequate, to date.