The Experts below are selected from a list of 114 Experts worldwide ranked by ideXlab platform

Bengterik Bengtsson - One of the best experts on this subject based on the ideXlab platform.

  • oestrogens have no Hormonal Effect on the development and reproduction of the harpacticoid copepod nitocra spinipes
    Marine Pollution Bulletin, 2001
    Co-Authors: Magnus Breitholtz, Bengterik Bengtsson
    Abstract:

    In recent years, reports have described endocrine-disruptive Effects of environmental oestrogens in fish, but little is known about similar Effects in crustaceans. The objective of the present study was therefore to examine whether the oestrogens 17-β-oestradiol, 17-α-ethynylestradiol and diethylstilbestrol (DES), could affect mortality, larval development rate, fecundity and sex ratio in the sexually reproducing harpacticoid copepod Nitocra spinipes. Newly released nauplii (<24-h old) were exposed to 1/1000, 1/100 and 1/10 (nominal concentrations) of each oestrogen's 96 h-LC50 value for ≤18 days at 22±1°C. The percentage of gravid females and the number of developed copepodites were both reduced at 0.03 mg l−1 DES, although the latter response was not significant. None of the other two oestrogens induced any measurable Effects. Since the only observed significant response appeared at a DES concentration no more than 10 times below the 96 h-LC50 value, there is no evidence of endocrine-disruptive activity in N. spinipes exposed to oestrogens.

  • Oestrogens have no Hormonal Effect on the development and reproduction of the harpacticoid copepod Nitocra spinipes.
    Marine Pollution Bulletin, 2001
    Co-Authors: Magnus Breitholtz, Bengterik Bengtsson
    Abstract:

    In recent years, reports have described endocrine-disruptive Effects of environmental oestrogens in fish, but little is known about similar Effects in crustaceans. The objective of the present study was therefore to examine whether the oestrogens 17-β-oestradiol, 17-α-ethynylestradiol and diethylstilbestrol (DES), could affect mortality, larval development rate, fecundity and sex ratio in the sexually reproducing harpacticoid copepod Nitocra spinipes. Newly released nauplii (

Gerald D Weinstein - One of the best experts on this subject based on the ideXlab platform.

  • Hormonal Effect on psoriasis in pregnancy and post partum
    Archives of Dermatology, 2005
    Co-Authors: Jenny E Murase, Kenneth Chan, Thomas J Garite, Dan M Cooper, Gerald D Weinstein
    Abstract:

    OBJECTIVES: To investigate prospectively how psoriasis fluctuates in pregnancy and post partum and to correlate hormone levels in pregnancy (progesterone and estrogens) with psoriatic change. DESIGN: Psoriatic body surface area (BSA) in pregnant patients with psoriasis (study group) and nonpregnant, menstruating patients with psoriasis (control group) were assessed 5 times over a year. Hormone levels (progesterone and estrogens) were measured in the study group and correlated with change in BSA. SETTING: University-affiliated obstetric and dermatology clinics. PATIENTS: Forty-seven pregnant patients in the psoriasis group and 27 nonpregnant, menstruating patients in the control group. RESULTS: During pregnancy, 55% of the patients reported improvement, 21% reported no change, and 23% reported worsening. However, post partum, only 9% of patients reported improvement, 26% reported no change, and 65% reported worsening. Psoriatic BSA decreased significantly from 10 to 20 weeks' gestation (P<.001) compared with controls, whereas BSA increased significantly by 6 weeks post partum (P = .001) compared with controls. In patients with 10% or greater psoriatic BSA who reported improvement (n = 16; mean BSA, 40%), lesions decreased by 83.8% during pregnancy. There were significant or near significant correlations between improvement in BSA and estradiol (P = .009, r = 0.648), estriol (P = .06, r = 0.491), and the ratio of estrogen to progesterone (P = .006, r = 0.671). CONCLUSION: High levels of estrogen correlated with improvement in psoriasis, whereas progesterone levels did not correlate with psoriatic change.

  • Hormonal Effect on psoriasis in pregnancy and post partum
    Archives of Dermatology, 2005
    Co-Authors: Jenny E Murase, Kenneth Chan, Thomas J Garite, Dan M Cooper, Gerald D Weinstein
    Abstract:

    OBJECTIVES: To investigate prospectively how psoriasis fluctuates in pregnancy and post partum and to correlate hormone levels in pregnancy (progesterone and estrogens) with psoriatic change. DESIGN: Psoriatic body surface area (BSA) in pregnant patients with psoriasis (study group) and nonpregnant, menstruating patients with psoriasis (control group) were assessed 5 times over a year. Hormone levels (progesterone and estrogens) were measured in the study group and correlated with change in BSA. SETTING: University-affiliated obstetric and dermatology clinics. PATIENTS: Forty-seven pregnant patients in the psoriasis group and 27 nonpregnant, menstruating patients in the control group. RESULTS: During pregnancy, 55% of the patients reported improvement, 21% reported no change, and 23% reported worsening. However, post partum, only 9% of patients reported improvement, 26% reported no change, and 65% reported worsening. Psoriatic BSA decreased significantly from 10 to 20 weeks' gestation (P

Magnus Breitholtz - One of the best experts on this subject based on the ideXlab platform.

  • oestrogens have no Hormonal Effect on the development and reproduction of the harpacticoid copepod nitocra spinipes
    Marine Pollution Bulletin, 2001
    Co-Authors: Magnus Breitholtz, Bengterik Bengtsson
    Abstract:

    In recent years, reports have described endocrine-disruptive Effects of environmental oestrogens in fish, but little is known about similar Effects in crustaceans. The objective of the present study was therefore to examine whether the oestrogens 17-β-oestradiol, 17-α-ethynylestradiol and diethylstilbestrol (DES), could affect mortality, larval development rate, fecundity and sex ratio in the sexually reproducing harpacticoid copepod Nitocra spinipes. Newly released nauplii (<24-h old) were exposed to 1/1000, 1/100 and 1/10 (nominal concentrations) of each oestrogen's 96 h-LC50 value for ≤18 days at 22±1°C. The percentage of gravid females and the number of developed copepodites were both reduced at 0.03 mg l−1 DES, although the latter response was not significant. None of the other two oestrogens induced any measurable Effects. Since the only observed significant response appeared at a DES concentration no more than 10 times below the 96 h-LC50 value, there is no evidence of endocrine-disruptive activity in N. spinipes exposed to oestrogens.

  • Oestrogens have no Hormonal Effect on the development and reproduction of the harpacticoid copepod Nitocra spinipes.
    Marine Pollution Bulletin, 2001
    Co-Authors: Magnus Breitholtz, Bengterik Bengtsson
    Abstract:

    In recent years, reports have described endocrine-disruptive Effects of environmental oestrogens in fish, but little is known about similar Effects in crustaceans. The objective of the present study was therefore to examine whether the oestrogens 17-β-oestradiol, 17-α-ethynylestradiol and diethylstilbestrol (DES), could affect mortality, larval development rate, fecundity and sex ratio in the sexually reproducing harpacticoid copepod Nitocra spinipes. Newly released nauplii (

Jenny E Murase - One of the best experts on this subject based on the ideXlab platform.

  • Hormonal Effect on psoriasis in pregnancy and post partum
    Archives of Dermatology, 2005
    Co-Authors: Jenny E Murase, Kenneth Chan, Thomas J Garite, Dan M Cooper, Gerald D Weinstein
    Abstract:

    OBJECTIVES: To investigate prospectively how psoriasis fluctuates in pregnancy and post partum and to correlate hormone levels in pregnancy (progesterone and estrogens) with psoriatic change. DESIGN: Psoriatic body surface area (BSA) in pregnant patients with psoriasis (study group) and nonpregnant, menstruating patients with psoriasis (control group) were assessed 5 times over a year. Hormone levels (progesterone and estrogens) were measured in the study group and correlated with change in BSA. SETTING: University-affiliated obstetric and dermatology clinics. PATIENTS: Forty-seven pregnant patients in the psoriasis group and 27 nonpregnant, menstruating patients in the control group. RESULTS: During pregnancy, 55% of the patients reported improvement, 21% reported no change, and 23% reported worsening. However, post partum, only 9% of patients reported improvement, 26% reported no change, and 65% reported worsening. Psoriatic BSA decreased significantly from 10 to 20 weeks' gestation (P<.001) compared with controls, whereas BSA increased significantly by 6 weeks post partum (P = .001) compared with controls. In patients with 10% or greater psoriatic BSA who reported improvement (n = 16; mean BSA, 40%), lesions decreased by 83.8% during pregnancy. There were significant or near significant correlations between improvement in BSA and estradiol (P = .009, r = 0.648), estriol (P = .06, r = 0.491), and the ratio of estrogen to progesterone (P = .006, r = 0.671). CONCLUSION: High levels of estrogen correlated with improvement in psoriasis, whereas progesterone levels did not correlate with psoriatic change.

  • Hormonal Effect on psoriasis in pregnancy and post partum
    Archives of Dermatology, 2005
    Co-Authors: Jenny E Murase, Kenneth Chan, Thomas J Garite, Dan M Cooper, Gerald D Weinstein
    Abstract:

    OBJECTIVES: To investigate prospectively how psoriasis fluctuates in pregnancy and post partum and to correlate hormone levels in pregnancy (progesterone and estrogens) with psoriatic change. DESIGN: Psoriatic body surface area (BSA) in pregnant patients with psoriasis (study group) and nonpregnant, menstruating patients with psoriasis (control group) were assessed 5 times over a year. Hormone levels (progesterone and estrogens) were measured in the study group and correlated with change in BSA. SETTING: University-affiliated obstetric and dermatology clinics. PATIENTS: Forty-seven pregnant patients in the psoriasis group and 27 nonpregnant, menstruating patients in the control group. RESULTS: During pregnancy, 55% of the patients reported improvement, 21% reported no change, and 23% reported worsening. However, post partum, only 9% of patients reported improvement, 26% reported no change, and 65% reported worsening. Psoriatic BSA decreased significantly from 10 to 20 weeks' gestation (P

Thomas J Garite - One of the best experts on this subject based on the ideXlab platform.

  • Hormonal Effect on psoriasis in pregnancy and post partum
    Archives of Dermatology, 2005
    Co-Authors: Jenny E Murase, Kenneth Chan, Thomas J Garite, Dan M Cooper, Gerald D Weinstein
    Abstract:

    OBJECTIVES: To investigate prospectively how psoriasis fluctuates in pregnancy and post partum and to correlate hormone levels in pregnancy (progesterone and estrogens) with psoriatic change. DESIGN: Psoriatic body surface area (BSA) in pregnant patients with psoriasis (study group) and nonpregnant, menstruating patients with psoriasis (control group) were assessed 5 times over a year. Hormone levels (progesterone and estrogens) were measured in the study group and correlated with change in BSA. SETTING: University-affiliated obstetric and dermatology clinics. PATIENTS: Forty-seven pregnant patients in the psoriasis group and 27 nonpregnant, menstruating patients in the control group. RESULTS: During pregnancy, 55% of the patients reported improvement, 21% reported no change, and 23% reported worsening. However, post partum, only 9% of patients reported improvement, 26% reported no change, and 65% reported worsening. Psoriatic BSA decreased significantly from 10 to 20 weeks' gestation (P<.001) compared with controls, whereas BSA increased significantly by 6 weeks post partum (P = .001) compared with controls. In patients with 10% or greater psoriatic BSA who reported improvement (n = 16; mean BSA, 40%), lesions decreased by 83.8% during pregnancy. There were significant or near significant correlations between improvement in BSA and estradiol (P = .009, r = 0.648), estriol (P = .06, r = 0.491), and the ratio of estrogen to progesterone (P = .006, r = 0.671). CONCLUSION: High levels of estrogen correlated with improvement in psoriasis, whereas progesterone levels did not correlate with psoriatic change.

  • Hormonal Effect on psoriasis in pregnancy and post partum
    Archives of Dermatology, 2005
    Co-Authors: Jenny E Murase, Kenneth Chan, Thomas J Garite, Dan M Cooper, Gerald D Weinstein
    Abstract:

    OBJECTIVES: To investigate prospectively how psoriasis fluctuates in pregnancy and post partum and to correlate hormone levels in pregnancy (progesterone and estrogens) with psoriatic change. DESIGN: Psoriatic body surface area (BSA) in pregnant patients with psoriasis (study group) and nonpregnant, menstruating patients with psoriasis (control group) were assessed 5 times over a year. Hormone levels (progesterone and estrogens) were measured in the study group and correlated with change in BSA. SETTING: University-affiliated obstetric and dermatology clinics. PATIENTS: Forty-seven pregnant patients in the psoriasis group and 27 nonpregnant, menstruating patients in the control group. RESULTS: During pregnancy, 55% of the patients reported improvement, 21% reported no change, and 23% reported worsening. However, post partum, only 9% of patients reported improvement, 26% reported no change, and 65% reported worsening. Psoriatic BSA decreased significantly from 10 to 20 weeks' gestation (P