The Experts below are selected from a list of 18 Experts worldwide ranked by ideXlab platform

Keith B Payton - One of the best experts on this subject based on the ideXlab platform.

  • postoperative care for samter s triad patients undergoing endoscopic sinus surgery a double blinded randomized controlled trial
    Laryngoscope, 2011
    Co-Authors: Brian W Rotenberg, Irene Zhang, Ian Arra, Keith B Payton
    Abstract:

    Objectives/Hypothesis: Evidence is lacking to guide the postoperative management of Samter's triad patients with chronic rhinosinusitis with polyposis (CRSwP) undergoing endoscopic sinus surgery (ESS). The purpose of this study was to compare three different standardized medication regimens prescribed to these patients after ESS. Study Design: Three-arm, randomized, double-blinded, controlled trial. Methods: Patients with Samter's triad undergoing ESS were postoperatively randomized into three medication regimens, those being saline irrigation alone (control group A), saline irrigation plus separate budesonide nasal spray (group B), and saline irrigation mixed with budesonide nasal spray (group C). Outcome measures were Sino-Nasal Outcome Test scores, Lund-Mackay computed tomography scores, and Lund-Kennedy endoscopic scores taken at preoperative baseline, and then at 6 months and 1 year postoperatively. Side effect profiles were also measured (adrenocorticotropic Hormone Blood Level ranges and intraocular pressure at the same interval points). Analysis of variance and χ2 analyses were conducted using a Bonferroni correction method and routine descriptive statistics. Inter- and intragroup comparisons were made. Results: Sixty subjects were recruited. All groups were equivalent at baseline in all outcomes. All intragroup analyses showed statistically and clinically significant improvement in disease status as compared to baseline (P .05). There was no treatment effect noted. Conclusions: In this study, nasal steroids did not confer any additional benefit over saline alone as post-ESS care for the Samter's triad CRSwP patient population.

  • Postoperative care for Samter's triad patients undergoing endoscopic sinus surgery: A double‐blinded, randomized controlled trial
    Laryngoscope, 2011
    Co-Authors: Brian W Rotenberg, Irene Zhang, Ian Arra, Keith B Payton
    Abstract:

    Objectives/Hypothesis: Evidence is lacking to guide the postoperative management of Samter's triad patients with chronic rhinosinusitis with polyposis (CRSwP) undergoing endoscopic sinus surgery (ESS). The purpose of this study was to compare three different standardized medication regimens prescribed to these patients after ESS. Study Design: Three-arm, randomized, double-blinded, controlled trial. Methods: Patients with Samter's triad undergoing ESS were postoperatively randomized into three medication regimens, those being saline irrigation alone (control group A), saline irrigation plus separate budesonide nasal spray (group B), and saline irrigation mixed with budesonide nasal spray (group C). Outcome measures were Sino-Nasal Outcome Test scores, Lund-Mackay computed tomography scores, and Lund-Kennedy endoscopic scores taken at preoperative baseline, and then at 6 months and 1 year postoperatively. Side effect profiles were also measured (adrenocorticotropic Hormone Blood Level ranges and intraocular pressure at the same interval points). Analysis of variance and χ2 analyses were conducted using a Bonferroni correction method and routine descriptive statistics. Inter- and intragroup comparisons were made. Results: Sixty subjects were recruited. All groups were equivalent at baseline in all outcomes. All intragroup analyses showed statistically and clinically significant improvement in disease status as compared to baseline (P .05). There was no treatment effect noted. Conclusions: In this study, nasal steroids did not confer any additional benefit over saline alone as post-ESS care for the Samter's triad CRSwP patient population.

Brian W Rotenberg - One of the best experts on this subject based on the ideXlab platform.

  • postoperative care for samter s triad patients undergoing endoscopic sinus surgery a double blinded randomized controlled trial
    Laryngoscope, 2011
    Co-Authors: Brian W Rotenberg, Irene Zhang, Ian Arra, Keith B Payton
    Abstract:

    Objectives/Hypothesis: Evidence is lacking to guide the postoperative management of Samter's triad patients with chronic rhinosinusitis with polyposis (CRSwP) undergoing endoscopic sinus surgery (ESS). The purpose of this study was to compare three different standardized medication regimens prescribed to these patients after ESS. Study Design: Three-arm, randomized, double-blinded, controlled trial. Methods: Patients with Samter's triad undergoing ESS were postoperatively randomized into three medication regimens, those being saline irrigation alone (control group A), saline irrigation plus separate budesonide nasal spray (group B), and saline irrigation mixed with budesonide nasal spray (group C). Outcome measures were Sino-Nasal Outcome Test scores, Lund-Mackay computed tomography scores, and Lund-Kennedy endoscopic scores taken at preoperative baseline, and then at 6 months and 1 year postoperatively. Side effect profiles were also measured (adrenocorticotropic Hormone Blood Level ranges and intraocular pressure at the same interval points). Analysis of variance and χ2 analyses were conducted using a Bonferroni correction method and routine descriptive statistics. Inter- and intragroup comparisons were made. Results: Sixty subjects were recruited. All groups were equivalent at baseline in all outcomes. All intragroup analyses showed statistically and clinically significant improvement in disease status as compared to baseline (P .05). There was no treatment effect noted. Conclusions: In this study, nasal steroids did not confer any additional benefit over saline alone as post-ESS care for the Samter's triad CRSwP patient population.

  • Postoperative care for Samter's triad patients undergoing endoscopic sinus surgery: A double‐blinded, randomized controlled trial
    Laryngoscope, 2011
    Co-Authors: Brian W Rotenberg, Irene Zhang, Ian Arra, Keith B Payton
    Abstract:

    Objectives/Hypothesis: Evidence is lacking to guide the postoperative management of Samter's triad patients with chronic rhinosinusitis with polyposis (CRSwP) undergoing endoscopic sinus surgery (ESS). The purpose of this study was to compare three different standardized medication regimens prescribed to these patients after ESS. Study Design: Three-arm, randomized, double-blinded, controlled trial. Methods: Patients with Samter's triad undergoing ESS were postoperatively randomized into three medication regimens, those being saline irrigation alone (control group A), saline irrigation plus separate budesonide nasal spray (group B), and saline irrigation mixed with budesonide nasal spray (group C). Outcome measures were Sino-Nasal Outcome Test scores, Lund-Mackay computed tomography scores, and Lund-Kennedy endoscopic scores taken at preoperative baseline, and then at 6 months and 1 year postoperatively. Side effect profiles were also measured (adrenocorticotropic Hormone Blood Level ranges and intraocular pressure at the same interval points). Analysis of variance and χ2 analyses were conducted using a Bonferroni correction method and routine descriptive statistics. Inter- and intragroup comparisons were made. Results: Sixty subjects were recruited. All groups were equivalent at baseline in all outcomes. All intragroup analyses showed statistically and clinically significant improvement in disease status as compared to baseline (P .05). There was no treatment effect noted. Conclusions: In this study, nasal steroids did not confer any additional benefit over saline alone as post-ESS care for the Samter's triad CRSwP patient population.

Ian Arra - One of the best experts on this subject based on the ideXlab platform.

  • postoperative care for samter s triad patients undergoing endoscopic sinus surgery a double blinded randomized controlled trial
    Laryngoscope, 2011
    Co-Authors: Brian W Rotenberg, Irene Zhang, Ian Arra, Keith B Payton
    Abstract:

    Objectives/Hypothesis: Evidence is lacking to guide the postoperative management of Samter's triad patients with chronic rhinosinusitis with polyposis (CRSwP) undergoing endoscopic sinus surgery (ESS). The purpose of this study was to compare three different standardized medication regimens prescribed to these patients after ESS. Study Design: Three-arm, randomized, double-blinded, controlled trial. Methods: Patients with Samter's triad undergoing ESS were postoperatively randomized into three medication regimens, those being saline irrigation alone (control group A), saline irrigation plus separate budesonide nasal spray (group B), and saline irrigation mixed with budesonide nasal spray (group C). Outcome measures were Sino-Nasal Outcome Test scores, Lund-Mackay computed tomography scores, and Lund-Kennedy endoscopic scores taken at preoperative baseline, and then at 6 months and 1 year postoperatively. Side effect profiles were also measured (adrenocorticotropic Hormone Blood Level ranges and intraocular pressure at the same interval points). Analysis of variance and χ2 analyses were conducted using a Bonferroni correction method and routine descriptive statistics. Inter- and intragroup comparisons were made. Results: Sixty subjects were recruited. All groups were equivalent at baseline in all outcomes. All intragroup analyses showed statistically and clinically significant improvement in disease status as compared to baseline (P .05). There was no treatment effect noted. Conclusions: In this study, nasal steroids did not confer any additional benefit over saline alone as post-ESS care for the Samter's triad CRSwP patient population.

  • Postoperative care for Samter's triad patients undergoing endoscopic sinus surgery: A double‐blinded, randomized controlled trial
    Laryngoscope, 2011
    Co-Authors: Brian W Rotenberg, Irene Zhang, Ian Arra, Keith B Payton
    Abstract:

    Objectives/Hypothesis: Evidence is lacking to guide the postoperative management of Samter's triad patients with chronic rhinosinusitis with polyposis (CRSwP) undergoing endoscopic sinus surgery (ESS). The purpose of this study was to compare three different standardized medication regimens prescribed to these patients after ESS. Study Design: Three-arm, randomized, double-blinded, controlled trial. Methods: Patients with Samter's triad undergoing ESS were postoperatively randomized into three medication regimens, those being saline irrigation alone (control group A), saline irrigation plus separate budesonide nasal spray (group B), and saline irrigation mixed with budesonide nasal spray (group C). Outcome measures were Sino-Nasal Outcome Test scores, Lund-Mackay computed tomography scores, and Lund-Kennedy endoscopic scores taken at preoperative baseline, and then at 6 months and 1 year postoperatively. Side effect profiles were also measured (adrenocorticotropic Hormone Blood Level ranges and intraocular pressure at the same interval points). Analysis of variance and χ2 analyses were conducted using a Bonferroni correction method and routine descriptive statistics. Inter- and intragroup comparisons were made. Results: Sixty subjects were recruited. All groups were equivalent at baseline in all outcomes. All intragroup analyses showed statistically and clinically significant improvement in disease status as compared to baseline (P .05). There was no treatment effect noted. Conclusions: In this study, nasal steroids did not confer any additional benefit over saline alone as post-ESS care for the Samter's triad CRSwP patient population.

Irene Zhang - One of the best experts on this subject based on the ideXlab platform.

  • postoperative care for samter s triad patients undergoing endoscopic sinus surgery a double blinded randomized controlled trial
    Laryngoscope, 2011
    Co-Authors: Brian W Rotenberg, Irene Zhang, Ian Arra, Keith B Payton
    Abstract:

    Objectives/Hypothesis: Evidence is lacking to guide the postoperative management of Samter's triad patients with chronic rhinosinusitis with polyposis (CRSwP) undergoing endoscopic sinus surgery (ESS). The purpose of this study was to compare three different standardized medication regimens prescribed to these patients after ESS. Study Design: Three-arm, randomized, double-blinded, controlled trial. Methods: Patients with Samter's triad undergoing ESS were postoperatively randomized into three medication regimens, those being saline irrigation alone (control group A), saline irrigation plus separate budesonide nasal spray (group B), and saline irrigation mixed with budesonide nasal spray (group C). Outcome measures were Sino-Nasal Outcome Test scores, Lund-Mackay computed tomography scores, and Lund-Kennedy endoscopic scores taken at preoperative baseline, and then at 6 months and 1 year postoperatively. Side effect profiles were also measured (adrenocorticotropic Hormone Blood Level ranges and intraocular pressure at the same interval points). Analysis of variance and χ2 analyses were conducted using a Bonferroni correction method and routine descriptive statistics. Inter- and intragroup comparisons were made. Results: Sixty subjects were recruited. All groups were equivalent at baseline in all outcomes. All intragroup analyses showed statistically and clinically significant improvement in disease status as compared to baseline (P .05). There was no treatment effect noted. Conclusions: In this study, nasal steroids did not confer any additional benefit over saline alone as post-ESS care for the Samter's triad CRSwP patient population.

  • Postoperative care for Samter's triad patients undergoing endoscopic sinus surgery: A double‐blinded, randomized controlled trial
    Laryngoscope, 2011
    Co-Authors: Brian W Rotenberg, Irene Zhang, Ian Arra, Keith B Payton
    Abstract:

    Objectives/Hypothesis: Evidence is lacking to guide the postoperative management of Samter's triad patients with chronic rhinosinusitis with polyposis (CRSwP) undergoing endoscopic sinus surgery (ESS). The purpose of this study was to compare three different standardized medication regimens prescribed to these patients after ESS. Study Design: Three-arm, randomized, double-blinded, controlled trial. Methods: Patients with Samter's triad undergoing ESS were postoperatively randomized into three medication regimens, those being saline irrigation alone (control group A), saline irrigation plus separate budesonide nasal spray (group B), and saline irrigation mixed with budesonide nasal spray (group C). Outcome measures were Sino-Nasal Outcome Test scores, Lund-Mackay computed tomography scores, and Lund-Kennedy endoscopic scores taken at preoperative baseline, and then at 6 months and 1 year postoperatively. Side effect profiles were also measured (adrenocorticotropic Hormone Blood Level ranges and intraocular pressure at the same interval points). Analysis of variance and χ2 analyses were conducted using a Bonferroni correction method and routine descriptive statistics. Inter- and intragroup comparisons were made. Results: Sixty subjects were recruited. All groups were equivalent at baseline in all outcomes. All intragroup analyses showed statistically and clinically significant improvement in disease status as compared to baseline (P .05). There was no treatment effect noted. Conclusions: In this study, nasal steroids did not confer any additional benefit over saline alone as post-ESS care for the Samter's triad CRSwP patient population.

Вікторія Акоповна Георгіянц - One of the best experts on this subject based on the ideXlab platform.

  • Pharmacotherapeutic directions of iodine herbal remedies use for different groups of thyroid deseases treatment
    ScienceRise, 2015
    Co-Authors: Інна Миколаївна Владимирова, Вікторія Акоповна Георгіянц
    Abstract:

    Recently, the increase of endocrine diseases is observed worldwide. Diabetes mellitus and thyroid gland pathologies are the most widespread. Endocrine diseases can be acute or chronic. In some cases, they are life threatening. There are different reasons of thyroid gland pathologies development. Both poor nutrition and poor quality water use, and unfavorable environmental conditions, including radiation, are among them. Iodine deficiency is determined to be one of the main reasons of these diseases. Aim. Determination of the pharmacotherapeutic directions of iodine herbal remedies use for different groups of thyroid diseases treatment. Methods. Thyroid stimulating action determination (primary screening and model pathology) has been carried out by the method of “goiter reaction” in rats at the Central Scientific-Research Laboratory of National University of Pharmacy. Determination of thyroid Hormone Blood Level in rats has been carried out at the Laboratory of Radioactive Endocrinology of the State Institution “Grigoriev Institute for medical Radiology NAMS of Ukraine”. Results. According to the research results generalization, correctness of developed algorithms was confirmed; peculiarities of the influence on pathological processes in thyroid, and prospects of implementation and use of herbs and herbal remedies for thyroid diseases prevention and treatment were determined. Conclusion. Obtained experimental data are actual for the modern medicine, and new scientific research, specifying their place in etiology, pathogenesis and peculiarities of clinical course of many diseases, will improve the efficiency of treatment and prevention of thyroid diseases