The Experts below are selected from a list of 158844 Experts worldwide ranked by ideXlab platform
William Mcguire - One of the best experts on this subject based on the ideXlab platform.
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nutrient enriched formula versus standard term formula for preterm infants following Hospital Discharge
Cochrane Database of Systematic Reviews, 2016Co-Authors: Lauren Young, Nicholas D Embleton, William McguireAbstract:Background Preterm infants are often growth-restricted at Hospital Discharge. Feeding infants after Hospital Discharge with nutrient-enriched formula rather than standard term formula might facilitate "catch-up" growth and improve development. Objectives To determine the effect of feeding nutrient-enriched formula compared with standard term formula on growth and development for preterm infants following Hospital Discharge. Search strategy The standard search strategy of the Cochrane Neonatal Review Group were used. This included searches of the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library, Issue 2, 2007), MEDLINE (1966 - May 2007), EMBASE (1980 - May 2007), CINAHL (1982 - May 2007), conference proceedings, and previous reviews. Selection criteria Randomised or quasi-randomised controlled trials that compared the effect of feeding preterm infants following Hospital Discharge with nutrient-enriched formula compared with standard term formula. Data collection and analysis Data was extracted using the standard methods of the Cochrane Neonatal Review Group, with separate evaluation of trial quality and data extraction by two authors, and synthesis of data using weighted mean difference and a fixed effects model for meta-analysis. Main results Seven trials were found that were eligible for inclusion. These recruited a total of 631 infants and were generally of good methodological quality. The trials found little evidence that feeding with nutrient-enriched formula milk affected growth and development. Because of differences in the way individual trials measured and presented outcomes, data synthesis was limited. Growth data from two trials found that, at six months post-term, infants fed with nutrient-enriched formula had statistically significantly lower weights [weighted mean difference: -601 (95% confidence interval -1028, -174) grams], lengths [-18.8 (-30.0, -7.6) millimetres], and head circumferences [-10.2 ( -18.0, -2.4) millimetres], than infants fed standard term formula. At 12 to 18 months post-term, meta-analyses of data from three trials did not find any statistically significant differences in growth parameters. However, examination of these meta-analyses demonstrated statistical heterogeneity. Meta-analyses of data from two trials did not reveal a statistically significant difference in Bayley Mental Development or Psychomotor Development Indices. There are not yet any data on growth or development through later childhood. Authors' conclusions The available data do not provide strong evidence that feeding preterm infants following Hospital Discharge with nutrient-enriched formula compared with standard term formula affects growth rates or development up to 18 months post-term.
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multinutrient fortification of human breast milk for preterm infants following Hospital Discharge
Cochrane Database of Systematic Reviews, 2013Co-Authors: Ginny Henderson, Tom Fahey, William McguireAbstract:Background Preterm infants are usually growth restricted at Hospital Discharge. Feeding preterm infants after Hospital Discharge with multinutrient fortified breast milk rather than unfortified breast milk may facilitate more rapid catch-up growth and improve neurodevelopmental outcomes. Objectives To determine the effect of feeding preterm infants following Hospital Discharge with multinutrient fortified human breast milk versus unfortified breast milk on growth and development. Search methods We used the standard search strategy of the Cochrane Neonatal Review Group. This included electronic searches of the Cochrane Central Register of Controlled Trials Register (CENTRAL, The Cochrane Library, 2012, Issue 3), MEDLINE, EMBASE and CINAHL (until August 2012), conference proceedings, and previous reviews. Selection criteria Randomised or quasi-randomised controlled trials that compared feeding preterm infants following Hospital Discharge with multinutrient fortified breast milk compared with unfortified human breast milk. Data collection and analysis We extracted data using the standard methods of the Cochrane Neonatal Review Group with separate evaluation of trial quality and data extraction by two review authors and synthesis of data using risk ratio, risk difference and mean difference. Main results We identified two small trials involving a total of 246 infants. These did not provide evidence that multinutrient fortification of breast milk for three to four months after Hospital Discharge affected rates of growth during infancy. One trial assessed infants at 18 months corrected age and did not find any statistically significant effects on neurodevelopmental outcomes. Authors' conclusions The limited available data do not provide convincing evidence that feeding preterm infants with multinutrient fortified breast milk compared with unfortified breast milk following Hospital Discharge affects important outcomes including growth rates during infancy. There are no data on long-term growth. Since fortifying breast milk for infants fed directly from the breast is logistically difficult and has the potential to interfere with breast feeding, it is important to determine if mothers would support further trials of this intervention.
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nutrient enriched formula milk versus human breast milk for preterm infants following Hospital Discharge
Cochrane Database of Systematic Reviews, 2007Co-Authors: Ginny Henderson, Tom Fahey, William McguireAbstract:Background: Preterm infants are often growth‐restricted at Hospital Discharge. Feeding infants after Hospital Discharge with nutrient‐enriched formula milk instead of human breast milk might facilitate "catch‐up" growth and improve development. Objectives: To determine the effect of feeding nutrient‐enriched formula compared with human breast milk on growth and development of preterm infants following Hospital Discharge. Search methods: The standard search strategy of the Cochrane Neonatal Review Group was used. This included searches of the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library, Issue 2, 2007), MEDLINE (1966 ‐ May 2007), EMBASE (1980 ‐ May 2007), CINAHL (1982 ‐ May 2007), conference proceedings, and previous reviews. Selection criteria: Randomised or quasi‐randomised controlled trials that compared feeding preterm infants following Hospital Discharge with nutrient‐enriched formula compared with human breast milk. Data collection and analysis: The standard methods of the Cochrane Neonatal Review Group were used, with separate evaluation of trial quality and data extraction by two review authors. Main results: No eligible trials were identified. Authors' conclusions: There are no data from randomised controlled trials to determine whether feeding preterm infants following Hospital Discharge with nutrient‐enriched formula milk versus human breast milk affects growth and development. Mothers who wish to breast feed, and their health care advisors, would require very clear evidence that feeding with a nutrient‐enriched formula milk had major advantages for their infants before electing not to feed (or to reduce feeding) with maternal breast milk. If evidence from trials that compared feeding preterm infants following Hospital Discharge with nutrient‐enriched versus standard formula milk demonstrated an effect on growth or development, then this might strengthen the case for undertaking trials of nutrient‐enriched formula milk versus human breast milk.
Kristie Carter - One of the best experts on this subject based on the ideXlab platform.
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stroke rehabilitation services to accelerate Hospital Discharge and provide home based care an overview and cost analysis
PharmacoEconomics, 2002Co-Authors: Craig S Anderson, Cliona Ni Mhurchu, Paul Brown, Kristie CarterAbstract:Background: Limited information exists on the best way to organise stroke rehabilitation after Hospital Discharge and the relative costs of such services.
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stroke rehabilitation services to accelerate Hospital Discharge and provide home based care an overview and cost analysis
PharmacoEconomics, 2002Co-Authors: Craig S Anderson, Cliona Ni Mhurchu, Paul Brown, Kristie CarterAbstract:Background: Limited information exists on the best way to organise stroke rehabilitation after Hospital Discharge and the relative costs of such services. Objective: To review the evidence of the cost effectiveness of services that accelerate Hospital Discharge and provide home-based rehabilitation for patients with acute stroke. Methods: A systematic review with economic analysis of published randomised clinical trials (available to March 2001) comparing early Hospital Discharge and domiciliary rehabilitation with usual care in patients with stroke was conducted. From included studies, data were extracted on study quality; major clinical outcomes including Hospital stay, death, institutionalisation, disability, and readmission rates; and resource use associated with Hospital stay, rehabilitation, and community services. The resources were priced using Australian dollars ($A) healthcare costs. The outcomes and costs of the new intervention were compared with standard care. Results: Seven published trials involving 1277 patients (54% men; mean age 73 years) were identified. The pooled data showed that overall, a policy of early Hospital Discharge and domiciliary rehabilitation reduced total length of stay by 13 days [95% confidence interval (CI): -19 to -7 days]. There was no significant effect on mortality (odds ratio = 0.95; 95% CI: 0.65 to 1.38) or other clinical outcomes making a cost minimisation analysis for the economic analysis appropriate. The overall mean costs were approximately 15% lower for the early Discharge intervention [$A16 016 ($US9941) versus $A18 350] ($US11 390)] compared with standard care. Conclusions: A policy of early Hospital Discharge and home-based rehabilitation for patients with stroke may reduce the use of Hospital beds without compromising clinical outcomes. Our analysis shows this service to be a cost saving alternative to conventional in-Hospital stroke rehabilitation for an important subgroup of patients with stroke-related disability.
Ginny Henderson - One of the best experts on this subject based on the ideXlab platform.
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multinutrient fortification of human breast milk for preterm infants following Hospital Discharge
Cochrane Database of Systematic Reviews, 2013Co-Authors: Ginny Henderson, Tom Fahey, William McguireAbstract:Background Preterm infants are usually growth restricted at Hospital Discharge. Feeding preterm infants after Hospital Discharge with multinutrient fortified breast milk rather than unfortified breast milk may facilitate more rapid catch-up growth and improve neurodevelopmental outcomes. Objectives To determine the effect of feeding preterm infants following Hospital Discharge with multinutrient fortified human breast milk versus unfortified breast milk on growth and development. Search methods We used the standard search strategy of the Cochrane Neonatal Review Group. This included electronic searches of the Cochrane Central Register of Controlled Trials Register (CENTRAL, The Cochrane Library, 2012, Issue 3), MEDLINE, EMBASE and CINAHL (until August 2012), conference proceedings, and previous reviews. Selection criteria Randomised or quasi-randomised controlled trials that compared feeding preterm infants following Hospital Discharge with multinutrient fortified breast milk compared with unfortified human breast milk. Data collection and analysis We extracted data using the standard methods of the Cochrane Neonatal Review Group with separate evaluation of trial quality and data extraction by two review authors and synthesis of data using risk ratio, risk difference and mean difference. Main results We identified two small trials involving a total of 246 infants. These did not provide evidence that multinutrient fortification of breast milk for three to four months after Hospital Discharge affected rates of growth during infancy. One trial assessed infants at 18 months corrected age and did not find any statistically significant effects on neurodevelopmental outcomes. Authors' conclusions The limited available data do not provide convincing evidence that feeding preterm infants with multinutrient fortified breast milk compared with unfortified breast milk following Hospital Discharge affects important outcomes including growth rates during infancy. There are no data on long-term growth. Since fortifying breast milk for infants fed directly from the breast is logistically difficult and has the potential to interfere with breast feeding, it is important to determine if mothers would support further trials of this intervention.
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nutrient enriched formula milk versus human breast milk for preterm infants following Hospital Discharge
Cochrane Database of Systematic Reviews, 2007Co-Authors: Ginny Henderson, Tom Fahey, William McguireAbstract:Background: Preterm infants are often growth‐restricted at Hospital Discharge. Feeding infants after Hospital Discharge with nutrient‐enriched formula milk instead of human breast milk might facilitate "catch‐up" growth and improve development. Objectives: To determine the effect of feeding nutrient‐enriched formula compared with human breast milk on growth and development of preterm infants following Hospital Discharge. Search methods: The standard search strategy of the Cochrane Neonatal Review Group was used. This included searches of the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library, Issue 2, 2007), MEDLINE (1966 ‐ May 2007), EMBASE (1980 ‐ May 2007), CINAHL (1982 ‐ May 2007), conference proceedings, and previous reviews. Selection criteria: Randomised or quasi‐randomised controlled trials that compared feeding preterm infants following Hospital Discharge with nutrient‐enriched formula compared with human breast milk. Data collection and analysis: The standard methods of the Cochrane Neonatal Review Group were used, with separate evaluation of trial quality and data extraction by two review authors. Main results: No eligible trials were identified. Authors' conclusions: There are no data from randomised controlled trials to determine whether feeding preterm infants following Hospital Discharge with nutrient‐enriched formula milk versus human breast milk affects growth and development. Mothers who wish to breast feed, and their health care advisors, would require very clear evidence that feeding with a nutrient‐enriched formula milk had major advantages for their infants before electing not to feed (or to reduce feeding) with maternal breast milk. If evidence from trials that compared feeding preterm infants following Hospital Discharge with nutrient‐enriched versus standard formula milk demonstrated an effect on growth or development, then this might strengthen the case for undertaking trials of nutrient‐enriched formula milk versus human breast milk.
Craig S Anderson - One of the best experts on this subject based on the ideXlab platform.
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stroke rehabilitation services to accelerate Hospital Discharge and provide home based care an overview and cost analysis
PharmacoEconomics, 2002Co-Authors: Craig S Anderson, Cliona Ni Mhurchu, Paul Brown, Kristie CarterAbstract:Background: Limited information exists on the best way to organise stroke rehabilitation after Hospital Discharge and the relative costs of such services.
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stroke rehabilitation services to accelerate Hospital Discharge and provide home based care an overview and cost analysis
PharmacoEconomics, 2002Co-Authors: Craig S Anderson, Cliona Ni Mhurchu, Paul Brown, Kristie CarterAbstract:Background: Limited information exists on the best way to organise stroke rehabilitation after Hospital Discharge and the relative costs of such services. Objective: To review the evidence of the cost effectiveness of services that accelerate Hospital Discharge and provide home-based rehabilitation for patients with acute stroke. Methods: A systematic review with economic analysis of published randomised clinical trials (available to March 2001) comparing early Hospital Discharge and domiciliary rehabilitation with usual care in patients with stroke was conducted. From included studies, data were extracted on study quality; major clinical outcomes including Hospital stay, death, institutionalisation, disability, and readmission rates; and resource use associated with Hospital stay, rehabilitation, and community services. The resources were priced using Australian dollars ($A) healthcare costs. The outcomes and costs of the new intervention were compared with standard care. Results: Seven published trials involving 1277 patients (54% men; mean age 73 years) were identified. The pooled data showed that overall, a policy of early Hospital Discharge and domiciliary rehabilitation reduced total length of stay by 13 days [95% confidence interval (CI): -19 to -7 days]. There was no significant effect on mortality (odds ratio = 0.95; 95% CI: 0.65 to 1.38) or other clinical outcomes making a cost minimisation analysis for the economic analysis appropriate. The overall mean costs were approximately 15% lower for the early Discharge intervention [$A16 016 ($US9941) versus $A18 350] ($US11 390)] compared with standard care. Conclusions: A policy of early Hospital Discharge and home-based rehabilitation for patients with stroke may reduce the use of Hospital beds without compromising clinical outcomes. Our analysis shows this service to be a cost saving alternative to conventional in-Hospital stroke rehabilitation for an important subgroup of patients with stroke-related disability.
Tom Fahey - One of the best experts on this subject based on the ideXlab platform.
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multinutrient fortification of human breast milk for preterm infants following Hospital Discharge
Cochrane Database of Systematic Reviews, 2013Co-Authors: Ginny Henderson, Tom Fahey, William McguireAbstract:Background Preterm infants are usually growth restricted at Hospital Discharge. Feeding preterm infants after Hospital Discharge with multinutrient fortified breast milk rather than unfortified breast milk may facilitate more rapid catch-up growth and improve neurodevelopmental outcomes. Objectives To determine the effect of feeding preterm infants following Hospital Discharge with multinutrient fortified human breast milk versus unfortified breast milk on growth and development. Search methods We used the standard search strategy of the Cochrane Neonatal Review Group. This included electronic searches of the Cochrane Central Register of Controlled Trials Register (CENTRAL, The Cochrane Library, 2012, Issue 3), MEDLINE, EMBASE and CINAHL (until August 2012), conference proceedings, and previous reviews. Selection criteria Randomised or quasi-randomised controlled trials that compared feeding preterm infants following Hospital Discharge with multinutrient fortified breast milk compared with unfortified human breast milk. Data collection and analysis We extracted data using the standard methods of the Cochrane Neonatal Review Group with separate evaluation of trial quality and data extraction by two review authors and synthesis of data using risk ratio, risk difference and mean difference. Main results We identified two small trials involving a total of 246 infants. These did not provide evidence that multinutrient fortification of breast milk for three to four months after Hospital Discharge affected rates of growth during infancy. One trial assessed infants at 18 months corrected age and did not find any statistically significant effects on neurodevelopmental outcomes. Authors' conclusions The limited available data do not provide convincing evidence that feeding preterm infants with multinutrient fortified breast milk compared with unfortified breast milk following Hospital Discharge affects important outcomes including growth rates during infancy. There are no data on long-term growth. Since fortifying breast milk for infants fed directly from the breast is logistically difficult and has the potential to interfere with breast feeding, it is important to determine if mothers would support further trials of this intervention.
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nutrient enriched formula milk versus human breast milk for preterm infants following Hospital Discharge
Cochrane Database of Systematic Reviews, 2007Co-Authors: Ginny Henderson, Tom Fahey, William McguireAbstract:Background: Preterm infants are often growth‐restricted at Hospital Discharge. Feeding infants after Hospital Discharge with nutrient‐enriched formula milk instead of human breast milk might facilitate "catch‐up" growth and improve development. Objectives: To determine the effect of feeding nutrient‐enriched formula compared with human breast milk on growth and development of preterm infants following Hospital Discharge. Search methods: The standard search strategy of the Cochrane Neonatal Review Group was used. This included searches of the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library, Issue 2, 2007), MEDLINE (1966 ‐ May 2007), EMBASE (1980 ‐ May 2007), CINAHL (1982 ‐ May 2007), conference proceedings, and previous reviews. Selection criteria: Randomised or quasi‐randomised controlled trials that compared feeding preterm infants following Hospital Discharge with nutrient‐enriched formula compared with human breast milk. Data collection and analysis: The standard methods of the Cochrane Neonatal Review Group were used, with separate evaluation of trial quality and data extraction by two review authors. Main results: No eligible trials were identified. Authors' conclusions: There are no data from randomised controlled trials to determine whether feeding preterm infants following Hospital Discharge with nutrient‐enriched formula milk versus human breast milk affects growth and development. Mothers who wish to breast feed, and their health care advisors, would require very clear evidence that feeding with a nutrient‐enriched formula milk had major advantages for their infants before electing not to feed (or to reduce feeding) with maternal breast milk. If evidence from trials that compared feeding preterm infants following Hospital Discharge with nutrient‐enriched versus standard formula milk demonstrated an effect on growth or development, then this might strengthen the case for undertaking trials of nutrient‐enriched formula milk versus human breast milk.
