The Experts below are selected from a list of 11814 Experts worldwide ranked by ideXlab platform
Jun Li - One of the best experts on this subject based on the ideXlab platform.
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host guest Interaction induced supramolecular amphiphilic star architecture and uniform nanovesicle formation for anticancer drug delivery
Nanoscale, 2016Co-Authors: Xia Song, Jun LiAbstract:A star polymer of poly[(R,S)-3-hydroxybutyrate] (PHB) with adamantyl end-terminals extended from an α-cyclodextrin (α-CD) core is designed. It subsequently self-assembles to form controllable and uniform nanovesicles induced by host–guest Interactions between heptakis(2,6-di-O-methyl)-β-CD and the adamantyl ends. The nanovesicles are suitable for loading and intracellular delivery of the anticancer drug doxorubicin.
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Host–guest Interaction induced supramolecular amphiphilic star architecture and uniform nanovesicle formation for anticancer drug delivery
Nanoscale, 2016Co-Authors: Xia Song, Jun LiAbstract:A star polymer of poly[(R,S)-3-hydroxybutyrate] (PHB) with adamantyl end-terminals extended from an α-cyclodextrin (α-CD) core is designed. It subsequently self-assembles to form controllable and uniform nanovesicles induced by host–guest Interactions between heptakis(2,6-di-O-methyl)-β-CD and the adamantyl ends. The nanovesicles are suitable for loading and intracellular delivery of the anticancer drug doxorubicin.
Huaping Xu - One of the best experts on this subject based on the ideXlab platform.
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Controllable Supramolecular Polymerization through Host-Guest Interaction and Photochemistry
ACS Macro Letters, 2015Co-Authors: Liulin Yang, Yunhao Bai, Xinxin Tan, Zhiqiang Wang, Huaping XuAbstract:A new method for controllable supramolecular polymerization based on ABBA type monomer and cucurbit[8]uril monomer through host−guest Interaction and photochemistry is reported. The molecular weight and polydispersity of supra-molecular polymers can be well controlled by tuning the molar ratio of these host and guest monomers or by tuning the isomer ratio of azobenzene groups in the guest monomers upon the competitive irradiation of lights. This research provides a general methodology for the control of supramolecular polymerization and the structure of supramolecular polymers. S upramolecular polymer chemistry has been an important interdisciplinary field that combines supramolecular chem-istry and polymer science. 1−10 With the development of this line of research, 11−30 the construction of supramolecular polymers is moving toward a controllable process for defined chain structures. 5,31−34 A well controlled supramolecular polymerization is undoubtedly beneficial to the study of structure−property relationships of supramolecular polymers, 35
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Supramolecular polymers bearing disulfide bonds
Polym. Chem., 2014Co-Authors: Hui Yang, Yunhao Bai, Banglu Yu, Zhiqiang Wang, Huaping XuAbstract:This work is aimed to report a new type of multiple stimuli-responsive supramolecular polymers by combining dynamic covalent bonds with cucurbit[8]uril (CB[8])-based Host-Guest Interaction. Supramonomer (DSN) containing a disulfide bond can bind with CB[8] to fabricate supramolecular polymers by host-enhanced [small pi]-[small pi] Interaction. Additionally{,} the dynamic nature of disulfide bonds and Host-Guest chemistry endow these supramolecular polymers with redox and guest competitive responsiveness{,} respectively.
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Supramolecular polymerization of supramonomers: a way for fabricating supramolecular polymers
Polym. Chem., 2014Co-Authors: Qiao Song, Xinxin Tan, Liulin Yang, Zhiqiang Wang, Fei Li, Huaping XuAbstract:This communication describes a new method of fabricating supramolecular polymers through supramolecular polymerization of supramonomers. To mix building blocks of Phe-Gly-Gly linked with an azobenzene group and cucurbit[8]uril (CB[8]) in a molar ratio of 2 : 1 in aqueous solutions{,} supramonomers were obtained by Host-Guest Interaction between tripeptide and CB[8]. Then supramolecular polymers were formed spontaneously by mixing the supramonomers with bis-[small beta]-cyclodextrins in a molar ratio of 1 : 1 in an aqueous solution through noncovalent Host-Guest complexation of the azobenzene group and [small beta]-cyclodextrin. Considering that various noncovalent Interactions can be used to drive the formation of supramonomers and the supramolecular polymerization of the supramonomers{,} this study can enrich the methodology of fabricating supramolecular polymers.
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Cucurbit[8]uril-based supramolecular polymers: promoting supramolecular polymerization by metal-coordination.
2013Co-Authors: Yiliu Liu, Xinxin Tan, Zehuan Huang, Zhiqiang Wang, Huaping XuAbstract:Linear supramolecular polymers were obtained in aqueous solution by employing cucurbit[8]uril-based Host-Guest Interaction as the driving force. Water-soluble monomers were prepared through direct metal-coordination. The rigid and bulky terpyridine-Fe linker can effectively enhance the monomer's solubility and suppress its cyclization, thereby promoting supramolecular polymerization.
Leyong Wang - One of the best experts on this subject based on the ideXlab platform.
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Configuration-independent AIE-active supramolecular polymers of cyanostilbene through the photo-stable host–guest Interaction of pillar[5]arene
Polymer Chemistry, 2017Co-Authors: Manivannan Kalavathi Dhinakaran, Weitao Gong, Ali Wajahat, Xiaojun Kuang, Leyong Wang, Guiling NingAbstract:Supramolecular polymerization-enabled, configuration-independent aggregation-induced emission (AIE) systems of cyanostilbene were achieved through host–guest Interactions between pillar[5]arene and nitrile triazole guests. Interestingly, host, control and control-guest lost its AIE upon photo-isomerization due to the absence of host–guest Interaction. 1H NMR, DOSY NMR and fluorescence studies of the supramolecular polymers before and after UV irradiation clearly indicated the significant role of photo-stable host–guest Interaction in enhancing and retaining AIE.
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ph responsive supramolecular vesicles assembled by water soluble pillar 5 arene and a bodipy photosensitizer for chemo photodynamic dual therapy
Chemical Communications, 2015Co-Authors: Lubo Meng, Leyong Wang, Yan Li, Wenyi Zhang, Dongqi Li, Xiaoyu Hu, Guigen LiAbstract:Supramolecular vesicles which can successfully encapsulate DOX and exhibit rapid drug release in a low-pH environment are constructed based on the host–guest Interaction of water-soluble pillar[5]arene and a BODIPY derivative. They show remarkable combination of chemo- and photodynamic activities, suggesting a promising drug nanocarrier.
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advanced supramolecular polymers constructed by orthogonal self assembly
Chemical Society Reviews, 2012Co-Authors: Shaolu Li, Tangxin Xiao, Leyong WangAbstract:Large aggregates, constructed by linking together monomer building blocks via non-covalent Interactions with polymer properties, are regarded as supramolecular polymers. Many kinds of non-covalent Interactions, such as metal–ligand coordination, hydrogen bonding, π–π stacking, ionic Interaction, and host–guest Interaction etc., can be involved in the binding Interactions of monomer building blocks, as well as in the modification of the side chain for the construction of variable supramolecular polymers. In this tutorial review, we summarized the reported supramolecular polymers fully- or partially-created from the combination of multiple non-covalent binding Interactions, mainly of two kinds, in the orthogonal way.
Guigen Li - One of the best experts on this subject based on the ideXlab platform.
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ph responsive supramolecular vesicles assembled by water soluble pillar 5 arene and a bodipy photosensitizer for chemo photodynamic dual therapy
Chemical Communications, 2015Co-Authors: Lubo Meng, Leyong Wang, Yan Li, Wenyi Zhang, Dongqi Li, Xiaoyu Hu, Guigen LiAbstract:Supramolecular vesicles which can successfully encapsulate DOX and exhibit rapid drug release in a low-pH environment are constructed based on the host–guest Interaction of water-soluble pillar[5]arene and a BODIPY derivative. They show remarkable combination of chemo- and photodynamic activities, suggesting a promising drug nanocarrier.
Akira Harada - One of the best experts on this subject based on the ideXlab platform.
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Highly Flexible, Tough, and Self-Healing Supramolecular Polymeric Materials Using Host–Guest Interaction
Macromolecular Rapid Communications, 2015Co-Authors: Masaki Nakahata, Yoshinori Takashima, Akira HaradaAbstract:Flexible, tough, and self-healable polymeric materials are promising to be a solution to the energy problem by substituting for conventional heavy materials. A fusion of supramolecular chemistry and polymer chemistry is a powerful method to create such intelligent materials. Here, a supramolecular polymeric material using multipoint molecular recognition between cyclodextrin (CD) and hydrophobic guest molecules at polymer side chain is reported. A transparent, flexible, and tough hydrogel (host–guest gel) is formed by a simple preparation procedure. The host–guest gel shows self-healing property in both wet state and dry state due to reversible nature of host–guest Interaction. The practical utility of the host–guest gel as a scratch curable coating is demonstrated.
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Highly Flexible, Tough, and Self‐Healing Supramolecular Polymeric Materials Using Host–Guest Interaction
Macromolecular Rapid Communications, 2015Co-Authors: Masaki Nakahata, Yoshinori Takashima, Akira HaradaAbstract:Flexible, tough, and self-healable polymeric materials are promising to be a solution to the energy problem by substituting for conventional heavy materials. A fusion of supramolecular chemistry and polymer chemistry is a powerful method to create such intelligent materials. Here, a supramolecular polymeric material using multipoint molecular recognition between cyclodextrin (CD) and hydrophobic guest molecules at polymer side chain is reported. A transparent, flexible, and tough hydrogel (host–guest gel) is formed by a simple preparation procedure. The host–guest gel shows self-healing property in both wet state and dry state due to reversible nature of host–guest Interaction. The practical utility of the host–guest gel as a scratch curable coating is demonstrated.
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preorganized hydrogel self healing properties of supramolecular hydrogels formed by polymerization of host guest monomers that contain cyclodextrins and hydrophobic guest groups
Advanced Materials, 2013Co-Authors: Takahiro Kakuta, Yoshinori Takashima, Masaki Nakahata, Miyuki Otsubo, Hiroyasu Yamaguchi, Akira HaradaAbstract:: Supramolecular hydrogels formed by a Host-Guest Interaction show self-healing properties. The cube-shaped hydrogels with β-cyclodextrin and adamantane guest molecules mend after being broken. The hydrogels sufficiently heal to form a single gel, and the initial strength is restored. Although contact between a freshly cut and uncut surface does not mend the gels, two freshly cut surfaces selectively mend.