The Experts below are selected from a list of 288 Experts worldwide ranked by ideXlab platform
B S Holla - One of the best experts on this subject based on the ideXlab platform.
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synthesis antimicrobial and anti inflammatory activities of some 1 2 4 triazolo 3 4 b 1 3 4 thiadiazoles and 1 2 4 triazolo 3 4 b 1 3 4 thiadiazines bearing trichlorophenyl moiety
European Journal of Medicinal Chemistry, 2008Co-Authors: Prakash Karegoudar, Boja Poojary, Jagdeesh D Prasad, Mithun Ashok, Manjathuru Mahalinga, B S HollaAbstract:Abstract The reaction of 2,3,5-trichlorobenzoic acid Hydrazide with carbon disulfide and potassium hydroxide followed by treatment with hydrazine hydrate afforded 3-(2,3,5-trichlorophenyl)-4-amino-1,2,4-triazole-5-thione (6). Alternatively, this triazole was also synthesized by fusing 2,3,5-trichlorobenzoic acid with thiocarboHydrazide. Condensation of (6) with various aromatic carboxylic acids in the presence of phosphorous oxychloride or with phenacyl bromides afforded two series of fused heterocycles namely 6-(substituted aryl)-3-(2,3,5-trichlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadizoles (7) and 6-(substituted aryl)-3-(2,3,5-trichlorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines (8), respectively. The structures of these newly synthesized compounds are characterised by elemental analysis, IR, 1H NMR and mass spectroscopic studies. All the synthesized compounds were screened for their antimicrobial and anti-inflammatory activities. Some of the compounds exhibited promising antimicrobial and anti-inflammatory activities.
Prakash Karegoudar - One of the best experts on this subject based on the ideXlab platform.
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synthesis antimicrobial and anti inflammatory activities of some 1 2 4 triazolo 3 4 b 1 3 4 thiadiazoles and 1 2 4 triazolo 3 4 b 1 3 4 thiadiazines bearing trichlorophenyl moiety
European Journal of Medicinal Chemistry, 2008Co-Authors: Prakash Karegoudar, Boja Poojary, Jagdeesh D Prasad, Mithun Ashok, Manjathuru Mahalinga, B S HollaAbstract:Abstract The reaction of 2,3,5-trichlorobenzoic acid Hydrazide with carbon disulfide and potassium hydroxide followed by treatment with hydrazine hydrate afforded 3-(2,3,5-trichlorophenyl)-4-amino-1,2,4-triazole-5-thione (6). Alternatively, this triazole was also synthesized by fusing 2,3,5-trichlorobenzoic acid with thiocarboHydrazide. Condensation of (6) with various aromatic carboxylic acids in the presence of phosphorous oxychloride or with phenacyl bromides afforded two series of fused heterocycles namely 6-(substituted aryl)-3-(2,3,5-trichlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadizoles (7) and 6-(substituted aryl)-3-(2,3,5-trichlorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines (8), respectively. The structures of these newly synthesized compounds are characterised by elemental analysis, IR, 1H NMR and mass spectroscopic studies. All the synthesized compounds were screened for their antimicrobial and anti-inflammatory activities. Some of the compounds exhibited promising antimicrobial and anti-inflammatory activities.
Boja Poojary - One of the best experts on this subject based on the ideXlab platform.
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facile synthesis cytotoxic and antimicrobial activity studies of a new group of 6 aryl 3 4 methylsulfonyl benzyl 7h 1 2 4 triazolo 3 4 b 1 3 4 thiadiazines
ChemInform, 2012Co-Authors: V Sumangala, Boja Poojary, N Chidananda, T Arulmoli, Shalini ShenoyAbstract:Acid Hydrazide (I) reacts with carbon disulfide (II) affording potassium dithiocarbazinate, which upon treatment with hydrazine hydrate undergoes ring closure.
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synthesis antimicrobial and anti inflammatory activities of some 1 2 4 triazolo 3 4 b 1 3 4 thiadiazoles and 1 2 4 triazolo 3 4 b 1 3 4 thiadiazines bearing trichlorophenyl moiety
European Journal of Medicinal Chemistry, 2008Co-Authors: Prakash Karegoudar, Boja Poojary, Jagdeesh D Prasad, Mithun Ashok, Manjathuru Mahalinga, B S HollaAbstract:Abstract The reaction of 2,3,5-trichlorobenzoic acid Hydrazide with carbon disulfide and potassium hydroxide followed by treatment with hydrazine hydrate afforded 3-(2,3,5-trichlorophenyl)-4-amino-1,2,4-triazole-5-thione (6). Alternatively, this triazole was also synthesized by fusing 2,3,5-trichlorobenzoic acid with thiocarboHydrazide. Condensation of (6) with various aromatic carboxylic acids in the presence of phosphorous oxychloride or with phenacyl bromides afforded two series of fused heterocycles namely 6-(substituted aryl)-3-(2,3,5-trichlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadizoles (7) and 6-(substituted aryl)-3-(2,3,5-trichlorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines (8), respectively. The structures of these newly synthesized compounds are characterised by elemental analysis, IR, 1H NMR and mass spectroscopic studies. All the synthesized compounds were screened for their antimicrobial and anti-inflammatory activities. Some of the compounds exhibited promising antimicrobial and anti-inflammatory activities.
Manjathuru Mahalinga - One of the best experts on this subject based on the ideXlab platform.
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synthesis antimicrobial and anti inflammatory activities of some 1 2 4 triazolo 3 4 b 1 3 4 thiadiazoles and 1 2 4 triazolo 3 4 b 1 3 4 thiadiazines bearing trichlorophenyl moiety
European Journal of Medicinal Chemistry, 2008Co-Authors: Prakash Karegoudar, Boja Poojary, Jagdeesh D Prasad, Mithun Ashok, Manjathuru Mahalinga, B S HollaAbstract:Abstract The reaction of 2,3,5-trichlorobenzoic acid Hydrazide with carbon disulfide and potassium hydroxide followed by treatment with hydrazine hydrate afforded 3-(2,3,5-trichlorophenyl)-4-amino-1,2,4-triazole-5-thione (6). Alternatively, this triazole was also synthesized by fusing 2,3,5-trichlorobenzoic acid with thiocarboHydrazide. Condensation of (6) with various aromatic carboxylic acids in the presence of phosphorous oxychloride or with phenacyl bromides afforded two series of fused heterocycles namely 6-(substituted aryl)-3-(2,3,5-trichlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadizoles (7) and 6-(substituted aryl)-3-(2,3,5-trichlorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines (8), respectively. The structures of these newly synthesized compounds are characterised by elemental analysis, IR, 1H NMR and mass spectroscopic studies. All the synthesized compounds were screened for their antimicrobial and anti-inflammatory activities. Some of the compounds exhibited promising antimicrobial and anti-inflammatory activities.
Mithun Ashok - One of the best experts on this subject based on the ideXlab platform.
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synthesis antimicrobial and anti inflammatory activities of some 1 2 4 triazolo 3 4 b 1 3 4 thiadiazoles and 1 2 4 triazolo 3 4 b 1 3 4 thiadiazines bearing trichlorophenyl moiety
European Journal of Medicinal Chemistry, 2008Co-Authors: Prakash Karegoudar, Boja Poojary, Jagdeesh D Prasad, Mithun Ashok, Manjathuru Mahalinga, B S HollaAbstract:Abstract The reaction of 2,3,5-trichlorobenzoic acid Hydrazide with carbon disulfide and potassium hydroxide followed by treatment with hydrazine hydrate afforded 3-(2,3,5-trichlorophenyl)-4-amino-1,2,4-triazole-5-thione (6). Alternatively, this triazole was also synthesized by fusing 2,3,5-trichlorobenzoic acid with thiocarboHydrazide. Condensation of (6) with various aromatic carboxylic acids in the presence of phosphorous oxychloride or with phenacyl bromides afforded two series of fused heterocycles namely 6-(substituted aryl)-3-(2,3,5-trichlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadizoles (7) and 6-(substituted aryl)-3-(2,3,5-trichlorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines (8), respectively. The structures of these newly synthesized compounds are characterised by elemental analysis, IR, 1H NMR and mass spectroscopic studies. All the synthesized compounds were screened for their antimicrobial and anti-inflammatory activities. Some of the compounds exhibited promising antimicrobial and anti-inflammatory activities.
