The Experts below are selected from a list of 246 Experts worldwide ranked by ideXlab platform
Anas Abdallah - One of the best experts on this subject based on the ideXlab platform.
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Correlation of Hydromyelia with subarachnoid hemorrhage–related hydrocephalus: an experimental study
Neurosurgical Review, 2020Co-Authors: Anas AbdallahAbstract:Although the central canal is an integral component of the cerebral ventricular system, central canal dilation has not been examined adequately during the progression of subarachnoid hemorrhage–related hydrocephalus (SAH-H). Central canal dilation–associated ependymal cell desquamation or subependymal membrane rupture has been rarely reported. Herein, we try to describe possible mechanisms of central canal dilation “Hydromyelia,” developing after SAH. A total of 25 New Zealand hybrid female rabbits were recruited. Five served as controls, and five received sham operations. In the remaining animals ( n = 15), 0.5 mL/kg of autologous blood was injected into the cisterna magna twice on 0 and 2nd days. Five of these animals died within a few days. A total of 10 survivor animals decapitated 3 weeks later, and the brains and cervical spinal cords were histologically examined. Central canal volumes, ependymal cell numbers on the canal surfaces, and the Evans’ indices of the ventricles were compared. On histological examination, central canal occlusion with desquamated ependymal cells and basement membrane rupture were evident. The mean Evans’ index of the brain ventricles was 0.31, the mean central canal volume was 1.054 mm^3, and the normal ependymal cell density was 4.210 / mm^2 in control animals; the respective values were 0.34, 1.287 mm^3, and 3.602 / mm^2 for sham-operated animals, and 0.41, 1.776 mm^3, and 2.923/mm^2 in the study group. The differences were statistically significant ( p < 0.05). Hydromyelia, an ignored complication of SAH-H, features ependymal cell desquamation, subependymal basement membrane destruction, blood cell accumulation on the subependymal cell basement membrane, and increased CSF pressure. Hydromyelia may be a significant complication following SAH.
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Correlation of Hydromyelia with subarachnoid hemorrhage–related hydrocephalus: an experimental study
Neurosurgical Review, 2020Co-Authors: Anas AbdallahAbstract:Although the central canal is an integral component of the cerebral ventricular system, central canal dilation has not been examined adequately during the progression of subarachnoid hemorrhage–related hydrocephalus (SAH-H). Central canal dilation–associated ependymal cell desquamation or subependymal membrane rupture has been rarely reported. Herein, we try to describe possible mechanisms of central canal dilation “Hydromyelia,” developing after SAH. A total of 25 New Zealand hybrid female rabbits were recruited. Five served as controls, and five received sham operations. In the remaining animals ( n = 15), 0.5 mL/kg of autologous blood was injected into the cisterna magna twice on 0 and 2nd days. Five of these animals died within a few days. A total of 10 survivor animals decapitated 3 weeks later, and the brains and cervical spinal cords were histologically examined. Central canal volumes, ependymal cell numbers on the canal surfaces, and the Evans’ indices of the ventricles were compared. On histological examination, central canal occlusion with desquamated ependymal cells and basement membrane rupture were evident. The mean Evans’ index of the brain ventricles was 0.31, the mean central canal volume was 1.054 mm^3, and the normal ependymal cell density was 4.210 / mm^2 in control animals; the respective values were 0.34, 1.287 mm^3, and 3.602 / mm^2 for sham-operated animals, and 0.41, 1.776 mm^3, and 2.923/mm^2 in the study group. The differences were statistically significant ( p < 0.05). Hydromyelia, an ignored complication of SAH-H, features ependymal cell desquamation, subependymal basement membrane destruction, blood cell accumulation on the subependymal cell basement membrane, and increased CSF pressure. Hydromyelia may be a significant complication following SAH.
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Correlation of Hydromyelia with subarachnoid hemorrhage-related hydrocephalus: an experimental study.
Neurosurgical review, 2020Co-Authors: Anas AbdallahAbstract:Although the central canal is an integral component of the cerebral ventricular system, central canal dilation has not been examined adequately during the progression of subarachnoid hemorrhage-related hydrocephalus (SAH-H). Central canal dilation-associated ependymal cell desquamation or subependymal membrane rupture has been rarely reported. Herein, we try to describe possible mechanisms of central canal dilation "Hydromyelia," developing after SAH. A total of 25 New Zealand hybrid female rabbits were recruited. Five served as controls, and five received sham operations. In the remaining animals (n = 15), 0.5 mL/kg of autologous blood was injected into the cisterna magna twice on 0 and 2nd days. Five of these animals died within a few days. A total of 10 survivor animals decapitated 3 weeks later, and the brains and cervical spinal cords were histologically examined. Central canal volumes, ependymal cell numbers on the canal surfaces, and the Evans' indices of the ventricles were compared. On histological examination, central canal occlusion with desquamated ependymal cells and basement membrane rupture were evident. The mean Evans' index of the brain ventricles was 0.31, the mean central canal volume was 1.054 mm3, and the normal ependymal cell density was 4.210/mm2 in control animals; the respective values were 0.34, 1.287 mm3, and 3.602/mm2 for sham-operated animals, and 0.41, 1.776 mm3, and 2.923/mm2 in the study group. The differences were statistically significant (p < 0.05). Hydromyelia, an ignored complication of SAH-H, features ependymal cell desquamation, subependymal basement membrane destruction, blood cell accumulation on the subependymal cell basement membrane, and increased CSF pressure. Hydromyelia may be a significant complication following SAH.
Domenico D'avella - One of the best experts on this subject based on the ideXlab platform.
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Hydromyelia associated with spinal lipoma of the conus: case report.
Spine, 2010Co-Authors: R Faggin, Paola Drigo, Luca Denaro, Stefano Sartori, Domenico D'avellaAbstract:STUDY DESIGN: A case report and literature review of the treatment of "noncommunicating" syringomyelia. OBJECTIVE.: The aim of this report is to document the timing and the treatment of Hydromyelia holocord after surgical treatment for both tethering and retethering of spinal lipoma. SUMMARY OF BACKGROUND DATA: Syringomyelia associated with spinal lipoma presents a different pathogenesis and treatment in comparison to the "communicating" Hydromyelia in the myelomeningocele. After the primary retethering operation performed in symptomatic patients, recurrent retethering can occur with an increase of the syringomyelia signs and symptoms. METHODS: Syringomyelia treated with a thin silastic tube passed from the syrinx to the subarachnoidal space for drainage and decompression. Prior operations were: (1) initial untethering at birth, (2) second untethering at 5 years of age, (3) posterior fossa and cervical decompression. RESULTS: Magnetic resonance imaging 6 months post shunt operation demonstrated decompression of the Hydromyelia holocord and syringobulbia with improvement of motor function of the legs and improvement in sensory symptoms. CONCLUSION: Usefulness of syrinx-subarachnoidal shunt is demonstrated in this case report after unsuccessful decompression and detethering. When the enlargement of the ependymal channel is greater than 50% of the spinal cord's diameter, neurologic, and urological symptoms are evident and the patient benefitted from cord untethering and syrinx drainage. (1) The terminal "noncommunicating" syringomyelia in lumbar sacral lipoma has been reported to be associated with retethering in spinal lipoma in the 25% of the cases. (2) The rise of distal syringomyelia isn't only linked to the kind of the spinal lipoma, but also to the difficulty to obtain the untethering and a smooth cerebrospinal fluid flow between the subarachnoidal space and the ependymal canal. (3) In patients with Hydromyelia holocord greater than the 50% of the spinal cord's diameter a myelotomy and insert an ependymal channel/syrinx to the subarachnoidal space shunt can resolve of the syrinx. In this case, the enlargement of the ependymal channel in "noncommunicating" syringomyelia associated with lumbosacral lipoma is greater than 50% of the spinal cord's diameter; neurologic and urological symptoms occurred and the patient benefited from cord untethering and concurrent syrinx drainage.
W. Jerry Oakes - One of the best experts on this subject based on the ideXlab platform.
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Delayed resolution of Chiari I-associated Hydromyelia after posterior fossa decompression: case report and review of the literature.
Neurosurgery, 2004Co-Authors: Kyle E. Doughty, R. Shane Tubbs, Daniel Webb, W. Jerry OakesAbstract:OBJECTIVE AND IMPORTANCE The expected time interval for resolution of Hydromyelia after Chiari I decompression is lacking in the literature. This case report highlights one instance of delayed resolution of Chiari-induced Hydromyelia. CLINICAL PRESENTATION We report an adolescent girl with a Chiari I malformation and Hydromyelia. INTERVENTION A suboccipital craniectomy and C1 laminectomy with intradural exploration and duraplasty were performed. Serial imaging at 1 and 2 years after posterior cranial fossa decompression with duraplasty demonstrated no change in the size of the Hydromyelia. At 3 years after surgery and before reoperation for continued Hydromyelia, repeat magnetic resonance imaging demonstrated significant diminution of the fluid cavity. If this Hydromyelia did resolve as a result of surgery, the interval for radiological observation clearly needs to be reconsidered. CONCLUSION Unfortunately, this is an area in which the literature is lacking. With this case as a nidus, studies are now necessary to determine the range of time necessary for Chiari I malformation-related Hydromyelia to resolve.
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Delayed resolution of Chiari I-associated Hydromyelia after posterior fossa decompression
Neurosurgery, 2004Co-Authors: Kyle Doughty, R. Shane Tubbs, Daniel Webb, W. Jerry OakesAbstract:OBJECTIVE AND IMPORTANCE: The expected time interval for resolution of hydromyella after Chiari I decompression is lacking in the literature. This case report highlights one instance of delayed resolution of Chiari-induced Hydromyelia. CLINICAL PRESENTATION: We report in adolescent gird with a Chiari I malformation and hydromyella. INTERVENTION: A suboccipital craniextomy and C1 laminectomy with intradural exploration and duraplasty were performed. Serial imaging at 1 and 2 years after posterior cranlat fossa decompnession with duraplasty demonstrated no change in the size of the Hydromyelia. At 3 years after surgery and before resperation for continued Hydromyelia, repeat magnetic resonance imaging demonstrated significant diminution of the fluid cavity. If this Hydromyelia did resolve as a result of surgery, the interval for radiological observation clearly needs to be reconsidered. CONCLUSION: Unfortunately, this is an area in which the literature is lacking. With this case as a nidus, studies are now necessary to determine the range of time necessary for Chiari I malformation-related Hydromyelia to resolve.
Jun Masuoka - One of the best experts on this subject based on the ideXlab platform.
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Curved Planar Reformation for the Evaluation of Hydromyelia in Patients With Scoliosis Associated With Spinal Dysraphism.
Spine, 2018Co-Authors: Fumitaka Yoshioka, Shoko Shimokawa, Motofumi Koguchi, Hiroshi Ito, Atsushi Ogata, Kouhei Inoue, Yukinori Takase, Tatsuya Tanaka, Yukiko Nakahara, Jun MasuokaAbstract:Study Design.A retrospective cohort study.Objective.Scoliosis and Hydromyelia have frequently been observed in patients with spinal dysraphism. We investigated the applicability of curved planar reformation (CPR) for evaluating Hydromyelia in patients with scoliosis associated with spinal dysraphism
R Faggin - One of the best experts on this subject based on the ideXlab platform.
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Hydromyelia associated with spinal lipoma of the conus: case report.
Spine, 2010Co-Authors: R Faggin, Paola Drigo, Luca Denaro, Stefano Sartori, Domenico D'avellaAbstract:STUDY DESIGN: A case report and literature review of the treatment of "noncommunicating" syringomyelia. OBJECTIVE.: The aim of this report is to document the timing and the treatment of Hydromyelia holocord after surgical treatment for both tethering and retethering of spinal lipoma. SUMMARY OF BACKGROUND DATA: Syringomyelia associated with spinal lipoma presents a different pathogenesis and treatment in comparison to the "communicating" Hydromyelia in the myelomeningocele. After the primary retethering operation performed in symptomatic patients, recurrent retethering can occur with an increase of the syringomyelia signs and symptoms. METHODS: Syringomyelia treated with a thin silastic tube passed from the syrinx to the subarachnoidal space for drainage and decompression. Prior operations were: (1) initial untethering at birth, (2) second untethering at 5 years of age, (3) posterior fossa and cervical decompression. RESULTS: Magnetic resonance imaging 6 months post shunt operation demonstrated decompression of the Hydromyelia holocord and syringobulbia with improvement of motor function of the legs and improvement in sensory symptoms. CONCLUSION: Usefulness of syrinx-subarachnoidal shunt is demonstrated in this case report after unsuccessful decompression and detethering. When the enlargement of the ependymal channel is greater than 50% of the spinal cord's diameter, neurologic, and urological symptoms are evident and the patient benefitted from cord untethering and syrinx drainage. (1) The terminal "noncommunicating" syringomyelia in lumbar sacral lipoma has been reported to be associated with retethering in spinal lipoma in the 25% of the cases. (2) The rise of distal syringomyelia isn't only linked to the kind of the spinal lipoma, but also to the difficulty to obtain the untethering and a smooth cerebrospinal fluid flow between the subarachnoidal space and the ependymal canal. (3) In patients with Hydromyelia holocord greater than the 50% of the spinal cord's diameter a myelotomy and insert an ependymal channel/syrinx to the subarachnoidal space shunt can resolve of the syrinx. In this case, the enlargement of the ependymal channel in "noncommunicating" syringomyelia associated with lumbosacral lipoma is greater than 50% of the spinal cord's diameter; neurologic and urological symptoms occurred and the patient benefited from cord untethering and concurrent syrinx drainage.
