The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Masaaki Miyashita - One of the best experts on this subject based on the ideXlab platform.
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Total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a unique putreanine trimer and putreanine tetramer acylpolyamine chain
Tetrahedron Letters, 1998Co-Authors: Hiroaki Saito, Terumi Nakajima, Masahiro Miyazawa, Yasuhiro Itagaki, Etsuko Yuri, Masaaki MiyashitaAbstract:Abstract The first total synthesis of NPTX-5 and NPTX-6, Joro spider ( Nephila clavata ) toxins having a 4-hydroxyindole nucleus and a unique putreanine trimer and tetramer acylpolyamine chain, respectively, has been achieved by the iterative use of a key azide compound.
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Total synthesis of nephilatoxin-1 (NPTX-1), a Joro spider (Nephila clavata) toxin having a 4-hydroxyindole nucleus
Tetrahedron Letters, 1997Co-Authors: Masaaki Miyashita, Masayuki Matsushita, Hiroaki Saito, Masahiro Miyazawa, Yasuhiro Itagaki, Terumi NakajimaAbstract:Abstract The first total synthesis of Nephilatoxin-1 (NPTX-1), a Joro spider ( Nephila clavata ) toxin having a 4-hydroxyindole nucleus, has been achieved by using two key azide intermediates.
Terumi Nakajima - One of the best experts on this subject based on the ideXlab platform.
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Total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a unique putreanine trimer and putreanine tetramer acylpolyamine chain
Tetrahedron Letters, 1998Co-Authors: Hiroaki Saito, Terumi Nakajima, Masahiro Miyazawa, Yasuhiro Itagaki, Etsuko Yuri, Masaaki MiyashitaAbstract:Abstract The first total synthesis of NPTX-5 and NPTX-6, Joro spider ( Nephila clavata ) toxins having a 4-hydroxyindole nucleus and a unique putreanine trimer and tetramer acylpolyamine chain, respectively, has been achieved by the iterative use of a key azide compound.
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Total synthesis of nephilatoxin-1 (NPTX-1), a Joro spider (Nephila clavata) toxin having a 4-hydroxyindole nucleus
Tetrahedron Letters, 1997Co-Authors: Masaaki Miyashita, Masayuki Matsushita, Hiroaki Saito, Masahiro Miyazawa, Yasuhiro Itagaki, Terumi NakajimaAbstract:Abstract The first total synthesis of Nephilatoxin-1 (NPTX-1), a Joro spider ( Nephila clavata ) toxin having a 4-hydroxyindole nucleus, has been achieved by using two key azide intermediates.
Peter Wipf - One of the best experts on this subject based on the ideXlab platform.
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5 Hydroxyindoles by intramolecular alkynol furan diels alder cycloaddition
ChemInform, 2013Co-Authors: Matthew G. Laporte, Ki Bum Hong, Peter WipfAbstract:Propargyl alcohols isolated after the first step undergo intramolecular cycloaddition under microwave irradiation to give the title compounds in good yields.
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5 Hydroxyindoles by intramolecular alkynol furan diels alder cycloaddition
Journal of Organic Chemistry, 2013Co-Authors: Matthew G. Laporte, Ki Bum Hong, Peter WipfAbstract:A convergent approach provides a convenient access to synthetically and biologically useful 3,4-disubstituted 5-Hydroxyindoles. The one-pot procedure uses microwave heating to initiate an intramolecular [4 + 2]-cycloaddition of an alkynol segment onto a furan followed by a fragmentation, aromatization, and N-Boc deprotection cascade. Yields range from 15 to 74%, with aromatic substituents providing better conversions. 4-Trimethylsilylated analogues undergo a 1,3-silatropic rearrangement to give the O-TMS ethers.
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5‑Hydroxyindoles by Intramolecular Alkynol–Furan Diels–Alder Cycloaddition
2013Co-Authors: Matthew Laporte, Ki Bum Hong, Peter WipfAbstract:A convergent approach provides a convenient access to synthetically and biologically useful 3,4-disubstituted 5-Hydroxyindoles. The one-pot procedure uses microwave heating to initiate an intramolecular [4 + 2]-cycloaddition of an alkynol segment onto a furan followed by a fragmentation, aromatization, and N-Boc deprotection cascade. Yields range from 15 to 74%, with aromatic substituents providing better conversions. 4-Trimethylsilylated analogues undergo a 1,3-silatropic rearrangement to give the O-TMS ethers
Hiroaki Saito - One of the best experts on this subject based on the ideXlab platform.
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Total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a unique putreanine trimer and putreanine tetramer acylpolyamine chain
Tetrahedron Letters, 1998Co-Authors: Hiroaki Saito, Terumi Nakajima, Masahiro Miyazawa, Yasuhiro Itagaki, Etsuko Yuri, Masaaki MiyashitaAbstract:Abstract The first total synthesis of NPTX-5 and NPTX-6, Joro spider ( Nephila clavata ) toxins having a 4-hydroxyindole nucleus and a unique putreanine trimer and tetramer acylpolyamine chain, respectively, has been achieved by the iterative use of a key azide compound.
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Total synthesis of nephilatoxin-1 (NPTX-1), a Joro spider (Nephila clavata) toxin having a 4-hydroxyindole nucleus
Tetrahedron Letters, 1997Co-Authors: Masaaki Miyashita, Masayuki Matsushita, Hiroaki Saito, Masahiro Miyazawa, Yasuhiro Itagaki, Terumi NakajimaAbstract:Abstract The first total synthesis of Nephilatoxin-1 (NPTX-1), a Joro spider ( Nephila clavata ) toxin having a 4-hydroxyindole nucleus, has been achieved by using two key azide intermediates.
Masahiro Miyazawa - One of the best experts on this subject based on the ideXlab platform.
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Total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a unique putreanine trimer and putreanine tetramer acylpolyamine chain
Tetrahedron Letters, 1998Co-Authors: Hiroaki Saito, Terumi Nakajima, Masahiro Miyazawa, Yasuhiro Itagaki, Etsuko Yuri, Masaaki MiyashitaAbstract:Abstract The first total synthesis of NPTX-5 and NPTX-6, Joro spider ( Nephila clavata ) toxins having a 4-hydroxyindole nucleus and a unique putreanine trimer and tetramer acylpolyamine chain, respectively, has been achieved by the iterative use of a key azide compound.
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Total synthesis of nephilatoxin-1 (NPTX-1), a Joro spider (Nephila clavata) toxin having a 4-hydroxyindole nucleus
Tetrahedron Letters, 1997Co-Authors: Masaaki Miyashita, Masayuki Matsushita, Hiroaki Saito, Masahiro Miyazawa, Yasuhiro Itagaki, Terumi NakajimaAbstract:Abstract The first total synthesis of Nephilatoxin-1 (NPTX-1), a Joro spider ( Nephila clavata ) toxin having a 4-hydroxyindole nucleus, has been achieved by using two key azide intermediates.