The Experts below are selected from a list of 297 Experts worldwide ranked by ideXlab platform
Fredric B. Meyer - One of the best experts on this subject based on the ideXlab platform.
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Prognostic significance of subdural Hygroma for post-traumatic hydrocephalus after decompressive craniectomy in the traumatic brain injury setting: a systematic review and meta-analysis
Neurosurgical Review, 2019Co-Authors: Victor M. Lu, Lucas P. Carlstrom, Avital Perry, Christopher S. Graffeo, Ricardo A. Domingo, Christopher C. Young, Fredric B. MeyerAbstract:Post-traumatic hydrocephalus (PTH) is a potentially morbid sequela of decompressive craniectomy for traumatic brain injury (TBI). Subdural Hygromas are commonly identified following decompressive craniectomy, but the clinical relevance and predictive relationship with PTH in this patient cohort is not completely understood. Survey of seven electronic databases from inception to June 2019 was conducted following PRISMA guidelines. Articles were screened against pre-specified criteria. Multivariate hazard ratios (HRs) for PTH by the presence of subdural Hygroma were extracted and pooled by meta-analysis of proportions with random effects modeling. We systematically identified nine pertinent studies describing outcomes of 1010 TBI patients managed by decompressive craniectomy. Of the overall cohort, there were 211 (21%) females and median age was 37.5 years (range 33–53). On presentation, median Glasgow Coma Scale was 7 (range, 5–8). In sum, PTH was reported in 228/840 (27%) cases, and subdural Hygroma was reported in 449/1010 (44%) cases across all studies. Pooling multivariate-derived HRs indicated that subdural Hygroma was a significant, independent predictor of PTH (HR, 7.1; 95% CI, 3.3–15.1). The certainty of this association was deemed low due to heterogeneity concerns. The presence of subdural Hygroma is associated with increased risk of PTH after decompressive craniectomy among TBI patients based on the current literature and may mandate closer clinical surveillance when detected. Prospective studies, including those of intracranial hydrodynamics following decompressive craniectomy in the setting of TBI, will better validate the certainty of these findings.
Sadahiro Shimada - One of the best experts on this subject based on the ideXlab platform.
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traumatic subdural Hygroma pathology and meningeal enhancement on magnetic resonance imaging
Neurosurgery, 1992Co-Authors: Mitsuhiro Hasegawa, Tetsumori Yamashima, Junkoh Yamashita, Masayuki Suzuki, Sadahiro ShimadaAbstract:: Five patients with traumatic subdural Hygroma are reported with reference to its pathology and meningeal enhancement on magnetic resonance imaging. Hygromas showed initially iso- and, later, high intensity on both T1- and T2-weighted images compared with the intensity of the cerebrospinal fluid. In all cases of the thick Hygromas, magnetic resonance imaging with gadolinium diethylene-triamine-pentaacetic acid showed meningeal enhancement. Intravenously injected radioisotope immediately flowed into the Hygromas, but computed tomographic cisternography and gross inspection during the surgery showed no evidence of an influx of cerebrospinal fluid into the Hygromas. Microscopic examination of the enhanced meninges revealed vascularized neomembrane with numerous fenestrations and pinocytosis underneath the dura mater. It is suggested from these data that the subdural neomembrane is associated with the development of the traumatic subdural Hygromas. Meningeal enhancement would be useful to clarify the growing mechanism of traumatic subdural Hygromas.
M I Evans - One of the best experts on this subject based on the ideXlab platform.
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First-trimester simple Hygroma: cause and outcome.
American journal of obstetrics and gynecology, 1993Co-Authors: M P Johnson, A Johnson, W Holzgreve, N B Isada, R J Wapner, M C Treadwell, S Heeger, M I EvansAbstract:First-trimester fetuses with simple nuchal Hygromas represent a population that is different from midgestation nuchal cystic Hygroma in terms of karyotype abnormalities and long-term prognosis. Sixty-eight consecutive fetuses diagnosed with simple nuchal Hygromas between 10 and 14 weeks' gestation were evaluated ultrasonographically and karyotyped. Those with normal chromosome complements were ultrasonographically monitored throughout the remainder of the pregnancy for resolution of their Hygromas. Twenty-three of 27 fetuses with normal karyotypes resolved their Hygromas within 4 weeks of diagnosis and were phenotypically normal at birth. Forty-one fetuses were karyotypically abnormal, with trisomy 21 being the most common abnormality. Fetuses with first-trimester simple nuchal Hygromas are at high risk for aneuploidy and should be offered prenatal testing. Such fetuses with normal karyotypes will likely resolve their Hygromas by 18 weeks' gestation, and most will be phenotypically normal at birth.
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first trimester simple Hygroma cause and outcome
American Journal of Obstetrics and Gynecology, 1993Co-Authors: M P Johnson, A Johnson, W Holzgreve, N B Isada, R J Wapner, M C Treadwell, S Heeger, M I EvansAbstract:Objective: First-trimester fetuses with simple nuchal Hygromas represent a population that is different from midgestation nuchal cystic Hygroma in terms of karyotype abnormalities and long-term prognosis. Study Design: Sixty-eight consecutive fetuses diagnosed with simple nuchal Hygromas between 10 and 14 weeks' gestation were evaluated ultrasonographically and karyotyped. Those with normal chromosome complements were ultrasonographically monitored throughout the remainder of the pregnancy for resolution of their Hygromas. Results: Twenty-three of 27 fetuses with normal karyotypes resolved their Hygromas within 4 weeks of diagnosis and were phenotypically normal at birth. Forty-one fetuses were karyotypically abnormal, with trisomy 21 being the most common abnormality. Conclusions: Fetuses with first-trimester simple nuchal Hygromas are at high risk for aneuploidy and should be offered prenatal testing. Such fetuses with normal karyotypes will likely resolve their Hygromas by 18 weeks' gestation, and most will be phenotypically normal at birth.
Kwok M Ho - One of the best experts on this subject based on the ideXlab platform.
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incidence and risk factors for post traumatic hydrocephalus following decompressive craniectomy for intractable intracranial hypertension and evacuation of mass lesions
Journal of Neurotrauma, 2012Co-Authors: Stephen Honeybul, Kwok M HoAbstract:Abstract There continues to be a considerable interest in decompressive craniectomy in the management of severe traumatic brain injury (TBI). Though technically straightforward, the procedure is not without significant complications. In this study we assessed the incidence and risk factors for the development of subdural Hygroma and hydrocephalus after decompressive craniectomy. A total of 195 patients who had had a decompressive craniectomy for severe TBI between 2004 and 2010 at the two major trauma centers in Western Australia were considered. Of the 166 patients who survived after the acute hospital stay, 93 (56%; 95% confidence interval [CI] 48,63%) developed subdural Hygroma; 45 patients (48%) had unilateral and 48 patients (52%) had bilateral subdural Hygromas. Of the 159 patients who survived more than 6 months after surgery, 72 (45%; 95% CI 38,53%) developed radiological evidence of ventriculomegaly, and 26 of these 72 patients (36%; 95% CI 26,48%) developed clinical evidence of hydrocephalus and...
Victor M. Lu - One of the best experts on this subject based on the ideXlab platform.
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Prognostic significance of subdural Hygroma for post-traumatic hydrocephalus after decompressive craniectomy in the traumatic brain injury setting: a systematic review and meta-analysis
Neurosurgical Review, 2019Co-Authors: Victor M. Lu, Lucas P. Carlstrom, Avital Perry, Christopher S. Graffeo, Ricardo A. Domingo, Christopher C. Young, Fredric B. MeyerAbstract:Post-traumatic hydrocephalus (PTH) is a potentially morbid sequela of decompressive craniectomy for traumatic brain injury (TBI). Subdural Hygromas are commonly identified following decompressive craniectomy, but the clinical relevance and predictive relationship with PTH in this patient cohort is not completely understood. Survey of seven electronic databases from inception to June 2019 was conducted following PRISMA guidelines. Articles were screened against pre-specified criteria. Multivariate hazard ratios (HRs) for PTH by the presence of subdural Hygroma were extracted and pooled by meta-analysis of proportions with random effects modeling. We systematically identified nine pertinent studies describing outcomes of 1010 TBI patients managed by decompressive craniectomy. Of the overall cohort, there were 211 (21%) females and median age was 37.5 years (range 33–53). On presentation, median Glasgow Coma Scale was 7 (range, 5–8). In sum, PTH was reported in 228/840 (27%) cases, and subdural Hygroma was reported in 449/1010 (44%) cases across all studies. Pooling multivariate-derived HRs indicated that subdural Hygroma was a significant, independent predictor of PTH (HR, 7.1; 95% CI, 3.3–15.1). The certainty of this association was deemed low due to heterogeneity concerns. The presence of subdural Hygroma is associated with increased risk of PTH after decompressive craniectomy among TBI patients based on the current literature and may mandate closer clinical surveillance when detected. Prospective studies, including those of intracranial hydrodynamics following decompressive craniectomy in the setting of TBI, will better validate the certainty of these findings.