Id Reaction

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M Aste - One of the best experts on this subject based on the ideXlab platform.

  • erythema multiforme Id Reaction in atypical dermatophytosis a case report
    Journal of The European Academy of Dermatology and Venereology, 2003
    Co-Authors: Laura Atzori, M Pau, M Aste
    Abstract:

    Background  Erythema multiforme (EM) is an uncommon mucocutaneous disorder, characterized by wIdespread erythematous-oedematous targetoId lesions, consIdered as a Reaction pattern to many different stimuli. Observation  Presentation is made of a classical EM eruption concomitant to an inflammatory, atypical dermatophytosis of the ala nasi, observed in a 37-year-old male at the Dermatology Department of Cagliari, Italy. Methods  Laboratory investigations revealed normal complete blood count and biochemistry profile. A direct microscopic examination with 20% potassium hydroxIde of the nasal skin scales and of the vibrissae indicated the presence of dermatophyte hyphae and spores invading the rhinothrix. Culture confirmed a Trycophyton mentagrophytes infection. Specific determination of antiviral immunity in the blood (TORCH) was negative for recent infections, while the cell-mediated response, investigated with a delayed skin multitest, showed a marked positivity for the tricophyton antigen. Systemic therapy with terbinafine (250 mg/day) led to complete clinical and mycological recovery of the atypical ringworm in 30 days. Multiforme lesions rapIdly improved and completely disappeared in 7 days. Conclusions  Id Reaction to a distant focus of dermatophyte infection very rarely presents as EM. The presented case fits all the essential criteria required for the diagnosis of an Id Reaction. The atypical clinical presentation of the ringworm infection, with marked involvement of the intranasal hairs, seems to have induced an inflammatory allergic response, similar to that evoked by sycosis.

Carlo Crosti - One of the best experts on this subject based on the ideXlab platform.

Borroni G. - One of the best experts on this subject based on the ideXlab platform.

  • Pompholyx of the hands after intravenous immunoglobulin therapy for clinically isolated syndrome: a paediatric case.
    2014
    Co-Authors: Grassi S, Savasta S, Ruffinazzi G, Carugno A, Borroni G.
    Abstract:

    Pompholyx is a common eruption of small vesicles on the palms, soles, and/or lateral aspects of the fingers. It has a multifactorial etiology, including genetic determinants, allergy to metals, and Id Reaction; rarely it is a drug-related sIde effect. We report a paediatric case of pompholyx of the hands related to the intravenous immunoglobulin (IVIG) therapy for Clinically Isolated Syndrome (CIS). A 10-year-old boy, received an IVIG therapy (Venital, Kedrion Spa, Italy) at a dose of 400 mg/kg daily for five days. The fifth day of IVIG infusion, a symmetrical vesicular eruption appeared on the palms of the hands and on lateral aspects of the fingers. The lesions improved with application of topical steroIds in few days. The mechanism of induction of pompholyx by IVIG therapy is unknown. A review of the Literature suggests the hypothesis that dyshIdrotic eczematous Reactions may be related not only to the type of IVIG, to the dose and the rates of infusion, but also to an allergic response to excipients and preservatives contained in the drug, probably elicited by an underlying neurological disease in some cases

  • Pompholyx of the hands after intravenous immunoglobulin therapy for clinically isolated syndrome: A paediatric case
    'SAGE Publications', 2014
    Co-Authors: Brazzelli Valeria, Grassi S, Savasta S, Ruffinazzi G, Carugno A, Marseglia G. L., Borroni G.
    Abstract:

    Pompholyx is a common eruption of small vesicles on the palms, soles, and/or lateral aspects of the fingers. It has a multifactorial etiology, including genetic determinants, allergy to metals, and Id Reaction; rarely it is a drug-related sIde effect. We report a paediatric case of pompholyx of the hands related to the intravenous immunoglobulin (IVIG) therapy for Clinically Isolated Syndrome (CIS). A 10-year-old boy, received an IVIG therapy (Venital®, Kedrion Spa, Italy) at a dose of 400 mg/kg daily for five days. The fifth day of IVIG infusion, a symmetrical vesicular eruption appeared on the palms of the hands and on lateral aspects of the fingers. The lesions improved with application of topical steroIds in few days. The mechanism of induction of pompholyx by IVIG therapy is unknown. A review of the Literature suggests the hypothesis that dyshIdrotic eczematous Reactions may be related not only to the type of IVIG, to the dose and the rates of infusion, but also to an allergic response to excipients and preservatives contained in the drug, probably elicited by an underlying neurological disease in some cases. Copyright © by BIOLIFE, s.a.s

Laura Atzori - One of the best experts on this subject based on the ideXlab platform.

  • erythema multiforme Id Reaction in atypical dermatophytosis a case report
    Journal of The European Academy of Dermatology and Venereology, 2003
    Co-Authors: Laura Atzori, M Pau, M Aste
    Abstract:

    Background  Erythema multiforme (EM) is an uncommon mucocutaneous disorder, characterized by wIdespread erythematous-oedematous targetoId lesions, consIdered as a Reaction pattern to many different stimuli. Observation  Presentation is made of a classical EM eruption concomitant to an inflammatory, atypical dermatophytosis of the ala nasi, observed in a 37-year-old male at the Dermatology Department of Cagliari, Italy. Methods  Laboratory investigations revealed normal complete blood count and biochemistry profile. A direct microscopic examination with 20% potassium hydroxIde of the nasal skin scales and of the vibrissae indicated the presence of dermatophyte hyphae and spores invading the rhinothrix. Culture confirmed a Trycophyton mentagrophytes infection. Specific determination of antiviral immunity in the blood (TORCH) was negative for recent infections, while the cell-mediated response, investigated with a delayed skin multitest, showed a marked positivity for the tricophyton antigen. Systemic therapy with terbinafine (250 mg/day) led to complete clinical and mycological recovery of the atypical ringworm in 30 days. Multiforme lesions rapIdly improved and completely disappeared in 7 days. Conclusions  Id Reaction to a distant focus of dermatophyte infection very rarely presents as EM. The presented case fits all the essential criteria required for the diagnosis of an Id Reaction. The atypical clinical presentation of the ringworm infection, with marked involvement of the intranasal hairs, seems to have induced an inflammatory allergic response, similar to that evoked by sycosis.

Campatelli Gianni - One of the best experts on this subject based on the ideXlab platform.