The Experts below are selected from a list of 1226676 Experts worldwide ranked by ideXlab platform
Nancy M Dunbar - One of the best experts on this subject based on the ideXlab platform.
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how do you decide which platelet bacterial risk mitigation strategy to select for your hospital based transfusion service
Transfusion, 2020Co-Authors: Wen Lu, Willy A Flegel, Nora R Ratcliffe, Alyssa Ziman, Paul M Ness, Meghan Delaney, Mark H. Yazer, Darrell J. Triulzi, Nancy M DunbarAbstract:: The United States Food and Drug Administration Final Guidance for Industry titled, "Bacterial Risk Control Strategies for Blood Collection Establishments and Transfusion Services to Enhance the Safety and Availability of Platelets for Transfusion" provides nine strategies for platelet bacterial risk mitigation. Even if it is assumed all strategies are comparable in terms of safety and efficacy, the decision of which to implement remains challenging. Some additional factors that warrant evaluation before selecting a strategy include the financial Impact, Process for implementation, logistics upon implementation, institutional acceptance by blood bank staff, administration and clinicians, and effect on platelet availability. To assist with this difficult choice, a panel of transfusion service physicians who have expertise on the topic and have already selected strategies for their transfusion services were recruited to provide varied perspectives. In addition, the use of a decision-making tool that objectively evaluates defined criteria for assessment of the nine strategies is described.
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how do you decide which platelet bacterial risk mitigation strategy to select for your hospital based transfusion service
Transfusion, 2020Co-Authors: Wen Lu, Willy A Flegel, Nora R Ratcliffe, Alyssa Ziman, Paul M Ness, Meghan Delaney, Mark H. Yazer, Darrell J. Triulzi, Nancy M DunbarAbstract:: The United States Food and Drug Administration Final Guidance for Industry titled, "Bacterial Risk Control Strategies for Blood Collection Establishments and Transfusion Services to Enhance the Safety and Availability of Platelets for Transfusion" provides nine strategies for platelet bacterial risk mitigation. Even if it is assumed all strategies are comparable in terms of safety and efficacy, the decision of which to implement remains challenging. Some additional factors that warrant evaluation before selecting a strategy include the financial Impact, Process for implementation, logistics upon implementation, institutional acceptance by blood bank staff, administration and clinicians, and effect on platelet availability. To assist with this difficult choice, a panel of transfusion service physicians who have expertise on the topic and have already selected strategies for their transfusion services were recruited to provide varied perspectives. In addition, the use of a decision-making tool that objectively evaluates defined criteria for assessment of the nine strategies is described.
Wen Lu - One of the best experts on this subject based on the ideXlab platform.
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how do you decide which platelet bacterial risk mitigation strategy to select for your hospital based transfusion service
Transfusion, 2020Co-Authors: Wen Lu, Willy A Flegel, Nora R Ratcliffe, Alyssa Ziman, Paul M Ness, Meghan Delaney, Mark H. Yazer, Darrell J. Triulzi, Nancy M DunbarAbstract:: The United States Food and Drug Administration Final Guidance for Industry titled, "Bacterial Risk Control Strategies for Blood Collection Establishments and Transfusion Services to Enhance the Safety and Availability of Platelets for Transfusion" provides nine strategies for platelet bacterial risk mitigation. Even if it is assumed all strategies are comparable in terms of safety and efficacy, the decision of which to implement remains challenging. Some additional factors that warrant evaluation before selecting a strategy include the financial Impact, Process for implementation, logistics upon implementation, institutional acceptance by blood bank staff, administration and clinicians, and effect on platelet availability. To assist with this difficult choice, a panel of transfusion service physicians who have expertise on the topic and have already selected strategies for their transfusion services were recruited to provide varied perspectives. In addition, the use of a decision-making tool that objectively evaluates defined criteria for assessment of the nine strategies is described.
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how do you decide which platelet bacterial risk mitigation strategy to select for your hospital based transfusion service
Transfusion, 2020Co-Authors: Wen Lu, Willy A Flegel, Nora R Ratcliffe, Alyssa Ziman, Paul M Ness, Meghan Delaney, Mark H. Yazer, Darrell J. Triulzi, Nancy M DunbarAbstract:: The United States Food and Drug Administration Final Guidance for Industry titled, "Bacterial Risk Control Strategies for Blood Collection Establishments and Transfusion Services to Enhance the Safety and Availability of Platelets for Transfusion" provides nine strategies for platelet bacterial risk mitigation. Even if it is assumed all strategies are comparable in terms of safety and efficacy, the decision of which to implement remains challenging. Some additional factors that warrant evaluation before selecting a strategy include the financial Impact, Process for implementation, logistics upon implementation, institutional acceptance by blood bank staff, administration and clinicians, and effect on platelet availability. To assist with this difficult choice, a panel of transfusion service physicians who have expertise on the topic and have already selected strategies for their transfusion services were recruited to provide varied perspectives. In addition, the use of a decision-making tool that objectively evaluates defined criteria for assessment of the nine strategies is described.
Huaizhong Li - One of the best experts on this subject based on the ideXlab platform.
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on the erosion Process on quartz crystals by the Impact of multiple high velocity micro particles
Tribology International, 2016Co-Authors: Huan Qi, Jun Wang, Huaizhong LiAbstract:Abstract A computational model using the discrete element method is presented to investigate the Impact Process of multiple micro-particles on a quartz crystal. It is shown that the Impacts initiate median and lateral cracks that degrade the strength of the substrate material and facilitate material removal in subsequent Impacts. Elemental materials are removed through breaking their contacts with all adjacent elements by crack propagation and intersection. A larger overlapping Impact condition between two Impacts is more efficient for material removal in the second Impact, but a total overlap does not yield the maximum material removal. The number of micro-cracks and the thickness of the cracked layer left on the eroded specimen are also studied in relation to the Impact conditions.
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Impact erosion by high velocity micro particles on a quartz crystal
Tribology International, 2015Co-Authors: Huan Qi, Huaizhong LiAbstract:Abstract A computational model using the discrete element method is presented to investigate the high velocity micro-particle Impact Process on a quartz crystal. The kinetic energy transfer from the Impact particles to the target material is discussed. It shows that within the conditions considered 60–88% of the Impact energy is consumed for crack formation and propagation, and the initiation of micro-cracks by an Impact is mainly attributed to the shear stresses, while tensile stresses create more lateral and median cracks in the subsurface of the target than shear stresses. It also shows that a smaller Impact angle with a lower particle velocity within the range considered in this study yields less subsurface damage to the target and also lower material erosion.
Huan Qi - One of the best experts on this subject based on the ideXlab platform.
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on the erosion Process on quartz crystals by the Impact of multiple high velocity micro particles
Tribology International, 2016Co-Authors: Huan Qi, Jun Wang, Huaizhong LiAbstract:Abstract A computational model using the discrete element method is presented to investigate the Impact Process of multiple micro-particles on a quartz crystal. It is shown that the Impacts initiate median and lateral cracks that degrade the strength of the substrate material and facilitate material removal in subsequent Impacts. Elemental materials are removed through breaking their contacts with all adjacent elements by crack propagation and intersection. A larger overlapping Impact condition between two Impacts is more efficient for material removal in the second Impact, but a total overlap does not yield the maximum material removal. The number of micro-cracks and the thickness of the cracked layer left on the eroded specimen are also studied in relation to the Impact conditions.
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Impact erosion by high velocity micro particles on a quartz crystal
Tribology International, 2015Co-Authors: Huan Qi, Huaizhong LiAbstract:Abstract A computational model using the discrete element method is presented to investigate the high velocity micro-particle Impact Process on a quartz crystal. The kinetic energy transfer from the Impact particles to the target material is discussed. It shows that within the conditions considered 60–88% of the Impact energy is consumed for crack formation and propagation, and the initiation of micro-cracks by an Impact is mainly attributed to the shear stresses, while tensile stresses create more lateral and median cracks in the subsurface of the target than shear stresses. It also shows that a smaller Impact angle with a lower particle velocity within the range considered in this study yields less subsurface damage to the target and also lower material erosion.
Alyssa Ziman - One of the best experts on this subject based on the ideXlab platform.
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how do you decide which platelet bacterial risk mitigation strategy to select for your hospital based transfusion service
Transfusion, 2020Co-Authors: Wen Lu, Willy A Flegel, Nora R Ratcliffe, Alyssa Ziman, Paul M Ness, Meghan Delaney, Mark H. Yazer, Darrell J. Triulzi, Nancy M DunbarAbstract:: The United States Food and Drug Administration Final Guidance for Industry titled, "Bacterial Risk Control Strategies for Blood Collection Establishments and Transfusion Services to Enhance the Safety and Availability of Platelets for Transfusion" provides nine strategies for platelet bacterial risk mitigation. Even if it is assumed all strategies are comparable in terms of safety and efficacy, the decision of which to implement remains challenging. Some additional factors that warrant evaluation before selecting a strategy include the financial Impact, Process for implementation, logistics upon implementation, institutional acceptance by blood bank staff, administration and clinicians, and effect on platelet availability. To assist with this difficult choice, a panel of transfusion service physicians who have expertise on the topic and have already selected strategies for their transfusion services were recruited to provide varied perspectives. In addition, the use of a decision-making tool that objectively evaluates defined criteria for assessment of the nine strategies is described.
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how do you decide which platelet bacterial risk mitigation strategy to select for your hospital based transfusion service
Transfusion, 2020Co-Authors: Wen Lu, Willy A Flegel, Nora R Ratcliffe, Alyssa Ziman, Paul M Ness, Meghan Delaney, Mark H. Yazer, Darrell J. Triulzi, Nancy M DunbarAbstract:: The United States Food and Drug Administration Final Guidance for Industry titled, "Bacterial Risk Control Strategies for Blood Collection Establishments and Transfusion Services to Enhance the Safety and Availability of Platelets for Transfusion" provides nine strategies for platelet bacterial risk mitigation. Even if it is assumed all strategies are comparable in terms of safety and efficacy, the decision of which to implement remains challenging. Some additional factors that warrant evaluation before selecting a strategy include the financial Impact, Process for implementation, logistics upon implementation, institutional acceptance by blood bank staff, administration and clinicians, and effect on platelet availability. To assist with this difficult choice, a panel of transfusion service physicians who have expertise on the topic and have already selected strategies for their transfusion services were recruited to provide varied perspectives. In addition, the use of a decision-making tool that objectively evaluates defined criteria for assessment of the nine strategies is described.
