The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Adeniyi C Adeola - One of the best experts on this subject based on the ideXlab platform.
-
population genomics reveals Incipient Speciation introgression and adaptation in the african mona monkey cercopithecus mona
Molecular Biology and Evolution, 2021Co-Authors: Adeola Oluwakemi Ayoola, Baolin Zhang, Richard P Meisel, Lotanna M Nneji, Yong Shao, Olanrewaju B Morenikeji, Adeniyi C AdeolaAbstract:Guenons (tribe Cercopithecini) are the most widely distributed non-human primate in the tropical forest belt of Africa and show considerable phenotypic, taxonomic, and ecological diversity. However, genomic information for most species within this group is still lacking. Here, we present a high-quality de novo genome (total 2.90 Gb, contig N50 equal to 22.7 Mb) of the mona monkey (Cercopithecus mona), together with genome resequencing data of 13 individuals sampled across Nigeria. Our results showed differentiation between populations from East and West of the Niger River ∼84 thousands years ago and potential ancient introgression in the East population from other mona group species. The PTPRK, FRAS1, BNC2, and EDN3 genes related to pigmentation displayed signals of introgression in the East population. Genomic scans suggest that immunity genes such as AKT3 and IL13 (possibly involved in simian immunodeficiency virus defense), and G6PD, a gene involved in malaria resistance, are under positive natural selection. Our study gives insights into differentiation, natural selection and introgression in guenons.
-
population genomics reveals Incipient Speciation introgression and adaptation in the african mona monkey cercopithecus mona
Molecular Biology and Evolution, 2021Co-Authors: Adeola Oluwakemi Ayoola, Baolin Zhang, Richard P Meisel, Lotanna M Nneji, Yong Shao, Olanrewaju B Morenikeji, Adeniyi C AdeolaAbstract:Guenons (tribe Cercopithecini) are the most widely distributed nonhuman primate in the tropical forest belt of Africa and show considerable phenotypic, taxonomic, and ecological diversity. However, genomic information for most species within this group is still lacking. Here, we present a high-quality de novo genome (total 2.90 Gb, contig N50 equal to 22.7 Mb) of the mona monkey (Cercopithecus mona), together with genome resequencing data of 13 individuals sampled across Nigeria. Our results showed differentiation between populations from East and West of the Niger River ∼84 ka and potential ancient introgression in the East population from other mona group species. The PTPRK, FRAS1, BNC2, and EDN3 genes related to pigmentation displayed signals of introgression in the East population. Genomic scans suggest that immunity genes such as AKT3 and IL13 (possibly involved in simian immunodeficiency virus defense), and G6PD, a gene involved in malaria resistance, are under positive natural selection. Our study gives insights into differentiation, natural selection, and introgression in guenons.
Ryan Bracewell - One of the best experts on this subject based on the ideXlab platform.
-
rapid neo sex chromosome evolution and Incipient Speciation in a major forest pest
Nature Communications, 2017Co-Authors: Ryan Bracewell, Barbara J. Bentz, Brian T Sullivan, Jeffrey M. GoodAbstract:Genome evolution is predicted to be rapid following the establishment of new (neo) sex chromosomes, but it is not known if neo-sex chromosome evolution plays an important role in Speciation. Here we combine extensive crossing experiments with population and functional genomic data to examine neo-XY chromosome evolution and Incipient Speciation in the mountain pine beetle. We find a broad continuum of intrinsic incompatibilities in hybrid males that increase in strength with geographic distance between reproductively isolated populations. This striking progression of reproductive isolation is coupled with extensive gene specialization, natural selection, and elevated genetic differentiation on both sex chromosomes. Closely related populations isolated by hybrid male sterility also show fixation of alternative neo-Y haplotypes that differ in structure and male-specific gene content. Our results suggest that neo-sex chromosome evolution can drive rapid functional divergence between closely related populations irrespective of ecological drivers of divergence. The evolution of new sex chromosomes potentially generates reproductive isolation. Here, Bracewell et al. combine crossing experiments with population and functional genomics to characterize neo-sex chromosome evolution and Incipient Speciation in the mountain pine beetle, Dendroctonus ponderosae.
-
rapid neo sex chromosome evolution and Incipient Speciation in a major forest pest
Nature Communications, 2017Co-Authors: Ryan Bracewell, Barbara J. Bentz, Brian T Sullivan, Jeffrey M. GoodAbstract:Genome evolution is predicted to be rapid following the establishment of new (neo) sex chromosomes, but it is not known if neo-sex chromosome evolution plays an important role in Speciation. Here we combine extensive crossing experiments with population and functional genomic data to examine neo-XY chromosome evolution and Incipient Speciation in the mountain pine beetle. We find a broad continuum of intrinsic incompatibilities in hybrid males that increase in strength with geographic distance between reproductively isolated populations. This striking progression of reproductive isolation is coupled with extensive gene specialization, natural selection, and elevated genetic differentiation on both sex chromosomes. Closely related populations isolated by hybrid male sterility also show fixation of alternative neo-Y haplotypes that differ in structure and male-specific gene content. Our results suggest that neo-sex chromosome evolution can drive rapid functional divergence between closely related populations irrespective of ecological drivers of divergence.
Jeffrey M. Good - One of the best experts on this subject based on the ideXlab platform.
-
rapid neo sex chromosome evolution and Incipient Speciation in a major forest pest
Nature Communications, 2017Co-Authors: Ryan Bracewell, Barbara J. Bentz, Brian T Sullivan, Jeffrey M. GoodAbstract:Genome evolution is predicted to be rapid following the establishment of new (neo) sex chromosomes, but it is not known if neo-sex chromosome evolution plays an important role in Speciation. Here we combine extensive crossing experiments with population and functional genomic data to examine neo-XY chromosome evolution and Incipient Speciation in the mountain pine beetle. We find a broad continuum of intrinsic incompatibilities in hybrid males that increase in strength with geographic distance between reproductively isolated populations. This striking progression of reproductive isolation is coupled with extensive gene specialization, natural selection, and elevated genetic differentiation on both sex chromosomes. Closely related populations isolated by hybrid male sterility also show fixation of alternative neo-Y haplotypes that differ in structure and male-specific gene content. Our results suggest that neo-sex chromosome evolution can drive rapid functional divergence between closely related populations irrespective of ecological drivers of divergence. The evolution of new sex chromosomes potentially generates reproductive isolation. Here, Bracewell et al. combine crossing experiments with population and functional genomics to characterize neo-sex chromosome evolution and Incipient Speciation in the mountain pine beetle, Dendroctonus ponderosae.
-
rapid neo sex chromosome evolution and Incipient Speciation in a major forest pest
Nature Communications, 2017Co-Authors: Ryan Bracewell, Barbara J. Bentz, Brian T Sullivan, Jeffrey M. GoodAbstract:Genome evolution is predicted to be rapid following the establishment of new (neo) sex chromosomes, but it is not known if neo-sex chromosome evolution plays an important role in Speciation. Here we combine extensive crossing experiments with population and functional genomic data to examine neo-XY chromosome evolution and Incipient Speciation in the mountain pine beetle. We find a broad continuum of intrinsic incompatibilities in hybrid males that increase in strength with geographic distance between reproductively isolated populations. This striking progression of reproductive isolation is coupled with extensive gene specialization, natural selection, and elevated genetic differentiation on both sex chromosomes. Closely related populations isolated by hybrid male sterility also show fixation of alternative neo-Y haplotypes that differ in structure and male-specific gene content. Our results suggest that neo-sex chromosome evolution can drive rapid functional divergence between closely related populations irrespective of ecological drivers of divergence.
Adeola Oluwakemi Ayoola - One of the best experts on this subject based on the ideXlab platform.
-
population genomics reveals Incipient Speciation introgression and adaptation in the african mona monkey cercopithecus mona
Molecular Biology and Evolution, 2021Co-Authors: Adeola Oluwakemi Ayoola, Baolin Zhang, Richard P Meisel, Lotanna M Nneji, Yong Shao, Olanrewaju B Morenikeji, Adeniyi C AdeolaAbstract:Guenons (tribe Cercopithecini) are the most widely distributed non-human primate in the tropical forest belt of Africa and show considerable phenotypic, taxonomic, and ecological diversity. However, genomic information for most species within this group is still lacking. Here, we present a high-quality de novo genome (total 2.90 Gb, contig N50 equal to 22.7 Mb) of the mona monkey (Cercopithecus mona), together with genome resequencing data of 13 individuals sampled across Nigeria. Our results showed differentiation between populations from East and West of the Niger River ∼84 thousands years ago and potential ancient introgression in the East population from other mona group species. The PTPRK, FRAS1, BNC2, and EDN3 genes related to pigmentation displayed signals of introgression in the East population. Genomic scans suggest that immunity genes such as AKT3 and IL13 (possibly involved in simian immunodeficiency virus defense), and G6PD, a gene involved in malaria resistance, are under positive natural selection. Our study gives insights into differentiation, natural selection and introgression in guenons.
-
population genomics reveals Incipient Speciation introgression and adaptation in the african mona monkey cercopithecus mona
Molecular Biology and Evolution, 2021Co-Authors: Adeola Oluwakemi Ayoola, Baolin Zhang, Richard P Meisel, Lotanna M Nneji, Yong Shao, Olanrewaju B Morenikeji, Adeniyi C AdeolaAbstract:Guenons (tribe Cercopithecini) are the most widely distributed nonhuman primate in the tropical forest belt of Africa and show considerable phenotypic, taxonomic, and ecological diversity. However, genomic information for most species within this group is still lacking. Here, we present a high-quality de novo genome (total 2.90 Gb, contig N50 equal to 22.7 Mb) of the mona monkey (Cercopithecus mona), together with genome resequencing data of 13 individuals sampled across Nigeria. Our results showed differentiation between populations from East and West of the Niger River ∼84 ka and potential ancient introgression in the East population from other mona group species. The PTPRK, FRAS1, BNC2, and EDN3 genes related to pigmentation displayed signals of introgression in the East population. Genomic scans suggest that immunity genes such as AKT3 and IL13 (possibly involved in simian immunodeficiency virus defense), and G6PD, a gene involved in malaria resistance, are under positive natural selection. Our study gives insights into differentiation, natural selection, and introgression in guenons.
Lotanna M Nneji - One of the best experts on this subject based on the ideXlab platform.
-
population genomics reveals Incipient Speciation introgression and adaptation in the african mona monkey cercopithecus mona
Molecular Biology and Evolution, 2021Co-Authors: Adeola Oluwakemi Ayoola, Baolin Zhang, Richard P Meisel, Lotanna M Nneji, Yong Shao, Olanrewaju B Morenikeji, Adeniyi C AdeolaAbstract:Guenons (tribe Cercopithecini) are the most widely distributed non-human primate in the tropical forest belt of Africa and show considerable phenotypic, taxonomic, and ecological diversity. However, genomic information for most species within this group is still lacking. Here, we present a high-quality de novo genome (total 2.90 Gb, contig N50 equal to 22.7 Mb) of the mona monkey (Cercopithecus mona), together with genome resequencing data of 13 individuals sampled across Nigeria. Our results showed differentiation between populations from East and West of the Niger River ∼84 thousands years ago and potential ancient introgression in the East population from other mona group species. The PTPRK, FRAS1, BNC2, and EDN3 genes related to pigmentation displayed signals of introgression in the East population. Genomic scans suggest that immunity genes such as AKT3 and IL13 (possibly involved in simian immunodeficiency virus defense), and G6PD, a gene involved in malaria resistance, are under positive natural selection. Our study gives insights into differentiation, natural selection and introgression in guenons.
-
population genomics reveals Incipient Speciation introgression and adaptation in the african mona monkey cercopithecus mona
Molecular Biology and Evolution, 2021Co-Authors: Adeola Oluwakemi Ayoola, Baolin Zhang, Richard P Meisel, Lotanna M Nneji, Yong Shao, Olanrewaju B Morenikeji, Adeniyi C AdeolaAbstract:Guenons (tribe Cercopithecini) are the most widely distributed nonhuman primate in the tropical forest belt of Africa and show considerable phenotypic, taxonomic, and ecological diversity. However, genomic information for most species within this group is still lacking. Here, we present a high-quality de novo genome (total 2.90 Gb, contig N50 equal to 22.7 Mb) of the mona monkey (Cercopithecus mona), together with genome resequencing data of 13 individuals sampled across Nigeria. Our results showed differentiation between populations from East and West of the Niger River ∼84 ka and potential ancient introgression in the East population from other mona group species. The PTPRK, FRAS1, BNC2, and EDN3 genes related to pigmentation displayed signals of introgression in the East population. Genomic scans suggest that immunity genes such as AKT3 and IL13 (possibly involved in simian immunodeficiency virus defense), and G6PD, a gene involved in malaria resistance, are under positive natural selection. Our study gives insights into differentiation, natural selection, and introgression in guenons.
