The Experts below are selected from a list of 249 Experts worldwide ranked by ideXlab platform
Vincenzo Vingiani - One of the best experts on this subject based on the ideXlab platform.
-
individualized coronary calcium scoring at any tube voltage using a kv Independent reconstruction Algorithm
European Radiology, 2020Co-Authors: Vincenzo Vingiani, Andres F Abadia, Joseph U Schoepf, Andreas M Fischer, Akos Vargaszemes, Pooyan Sahbaee, Thomas Allmendinger, Dante A. Giovagnoli, Todd H Hudson, Riccardo MaranoAbstract:PURPOSE We prospectively investigate the feasibility of a patient specific automated tube voltage selection (ATVS)-based coronary artery calcium scoring (CACS) protocol, using a kV-Independent reconstruction Algorithm, to achieve significant dose reductions while maintaining the overall cardiac risk classification. METHODS Forty-three patients (mean age, 61.8 ± 9.0 years; 40% male) underwent a clinically indicated CACS scan at 120kVp, as well as an additional CACS acquisition using an individualized tube voltage between 70 and 130kVp based on the ATVS selection (CARE-kV). Datasets of the additional CACS scans were reconstructed using a kV-Independent Algorithm that allows for calcium scoring without changing the weighting threshold of 130HU, regardless of the tube voltage chosen for image acquisition. Agatston scores and radiation dose derived from the different ATVS-based CACS studies were compared to the standard acquisition at 120kVp. RESULTS Thirteen patients displayed a score of 0 and were correctly identified with the ATVS protocol. Agatston scores derived from the standard 120kVp (median, 33.4; IQR, 0-289.7) and the patient-tailored kV-Independent protocol (median, 47.5; IQR, 0-287.5) showed no significant differences (p = 0.094). The intra-class correlation for Agatston scores derived from the two different protocols was excellent (ICC = 0.99). The mean dose-length-product was 29.8 ± 11.9 mGy × cm using the ATVS protocol and 31.7 ± 11.4 mGy × cm using the standard 120kVp protocol (p 400) using the patient-tailored protocol. CONCLUSIONS ATVS-based CACS, using a kV-Independent Algorithm, allows for high accuracy compared to the standard 120kVp scanning, while significantly reducing radiation dose parameters. KEY POINTS • ATVS allows for CT scanning with reduced radiation dose values. • KV-Independent CACS is feasible at any tube voltage between 70 and 130 kVp. • ATVS applied to kV-Independent CACS can significantly reduce the radiation dose.
-
Individualized coronary calcium scoring at any tube voltage using a kV-Independent reconstruction Algorithm
European Radiology, 2020Co-Authors: Vincenzo Vingiani, Andres F Abadia, Andreas M Fischer, Pooyan Sahbaee, Thomas Allmendinger, U. Joseph Schoepf, Akos Varga-szemes, Dante A. Giovagnoli, H. Todd Hudson, Riccardo MaranoAbstract:Purpose We prospectively investigate the feasibility of a patient specific automated tube voltage selection (ATVS)-based coronary artery calcium scoring (CACS) protocol, using a kV-Independent reconstruction Algorithm, to achieve significant dose reductions while maintaining the overall cardiac risk classification. Methods Forty-three patients (mean age, 61.8 ± 9.0 years; 40% male) underwent a clinically indicated CACS scan at 120kVp, as well as an additional CACS acquisition using an individualized tube voltage between 70 and 130kVp based on the ATVS selection (CARE-kV). Datasets of the additional CACS scans were reconstructed using a kV-Independent Algorithm that allows for calcium scoring without changing the weighting threshold of 130HU, regardless of the tube voltage chosen for image acquisition. Agatston scores and radiation dose derived from the different ATVS-based CACS studies were compared to the standard acquisition at 120kVp. Results Thirteen patients displayed a score of 0 and were correctly identified with the ATVS protocol. Agatston scores derived from the standard 120kVp (median, 33.4; IQR, 0–289.7) and the patient-tailored kV-Independent protocol (median, 47.5; IQR, 0–287.5) showed no significant differences ( p = 0.094). The intra-class correlation for Agatston scores derived from the two different protocols was excellent (ICC = 0.99). The mean dose-length-product was 29.8 ± 11.9 mGy × cm using the ATVS protocol and 31.7 ± 11.4 mGy × cm using the standard 120kVp protocol ( p 400) using the patient-tailored protocol. Conclusions ATVS-based CACS, using a kV-Independent Algorithm, allows for high accuracy compared to the standard 120kVp scanning, while significantly reducing radiation dose parameters. Key Points • ATVS allows for CT scanning with reduced radiation dose values . • KV-Independent CACS is feasible at any tube voltage between 70 and 130 kVp. • ATVS applied to kV-Independent CACS can significantly reduce the radiation dose.
-
low kv coronary artery calcium scoring with tin filtration using a kv Independent reconstruction Algorithm
Journal of Cardiovascular Computed Tomography, 2020Co-Authors: Vincenzo Vingiani, Andres F Abadia, Joseph U Schoepf, Andreas M Fischer, Akos Vargaszemes, Pooyan Sahbaee, Thomas Allmendinger, Christian TescheAbstract:Abstract Purpose To investigate the accuracy of Agatston scoring and potential for radiation dose reduction of a coronary artery calcium scoring (CACS) CT protocol at 100 kV with tin filtration (Sn100kV) and kV-Independent iterative reconstruction, compared to standard 120 kV acquisitions. Materials and methods With IRB approval and in HIPAA compliance, 114 patients (61.8 ± 9.6 years; 66 men) underwent CACS using a standard 120 kV protocol and an additional Sn100kV CACS scan. The two datasets were reconstructed using a medium sharp convolution Algorithm and in addition the Sn100kV scans were reconstructed iteratively based on a kV-Independent Algorithm. Agatston scores and radiation dose values were compared between the Sn100kV and the standard 120 kV protocol. Results Median Agatston scores derived from the Sn100kV protocol with the kV-Independent Algorithm and the standard 120 kV were 21.4 (IQR, 0–173.8) and 24.7 (IQR, 0–171.1) respectively, with no significant differences (p=0.18). Agatston scores derived from the two different protocols had an excellent correlation (r = 0.99). The dose-length-product was 11.5 ± 4.1 mGy × cm using Sn100kV and 50.4 ± 24.9 mGy × cm using the standard 120 kV protocol (p 400) using the Sn100kV protocol. Conclusion CACS at Sn100kV using the kV-Independent iterative Algorithm is feasible and provides high accuracy when compared to standard 120 kV scanning. Furthermore, radiation dose can be significantly reduced for this screening application in a priori healthy individuals.
Riccardo Marano - One of the best experts on this subject based on the ideXlab platform.
-
Individualized coronary calcium scoring at any tube voltage using a kV-Independent reconstruction Algorithm
European Radiology, 2020Co-Authors: Vincenzo Vingiani, Andres F Abadia, Andreas M Fischer, Pooyan Sahbaee, Thomas Allmendinger, U. Joseph Schoepf, Akos Varga-szemes, Dante A. Giovagnoli, H. Todd Hudson, Riccardo MaranoAbstract:Purpose We prospectively investigate the feasibility of a patient specific automated tube voltage selection (ATVS)-based coronary artery calcium scoring (CACS) protocol, using a kV-Independent reconstruction Algorithm, to achieve significant dose reductions while maintaining the overall cardiac risk classification. Methods Forty-three patients (mean age, 61.8 ± 9.0 years; 40% male) underwent a clinically indicated CACS scan at 120kVp, as well as an additional CACS acquisition using an individualized tube voltage between 70 and 130kVp based on the ATVS selection (CARE-kV). Datasets of the additional CACS scans were reconstructed using a kV-Independent Algorithm that allows for calcium scoring without changing the weighting threshold of 130HU, regardless of the tube voltage chosen for image acquisition. Agatston scores and radiation dose derived from the different ATVS-based CACS studies were compared to the standard acquisition at 120kVp. Results Thirteen patients displayed a score of 0 and were correctly identified with the ATVS protocol. Agatston scores derived from the standard 120kVp (median, 33.4; IQR, 0–289.7) and the patient-tailored kV-Independent protocol (median, 47.5; IQR, 0–287.5) showed no significant differences ( p = 0.094). The intra-class correlation for Agatston scores derived from the two different protocols was excellent (ICC = 0.99). The mean dose-length-product was 29.8 ± 11.9 mGy × cm using the ATVS protocol and 31.7 ± 11.4 mGy × cm using the standard 120kVp protocol ( p 400) using the patient-tailored protocol. Conclusions ATVS-based CACS, using a kV-Independent Algorithm, allows for high accuracy compared to the standard 120kVp scanning, while significantly reducing radiation dose parameters. Key Points • ATVS allows for CT scanning with reduced radiation dose values . • KV-Independent CACS is feasible at any tube voltage between 70 and 130 kVp. • ATVS applied to kV-Independent CACS can significantly reduce the radiation dose.
-
individualized coronary calcium scoring at any tube voltage using a kv Independent reconstruction Algorithm
European Radiology, 2020Co-Authors: Vincenzo Vingiani, Andres F Abadia, Joseph U Schoepf, Andreas M Fischer, Akos Vargaszemes, Pooyan Sahbaee, Thomas Allmendinger, Dante A. Giovagnoli, Todd H Hudson, Riccardo MaranoAbstract:PURPOSE We prospectively investigate the feasibility of a patient specific automated tube voltage selection (ATVS)-based coronary artery calcium scoring (CACS) protocol, using a kV-Independent reconstruction Algorithm, to achieve significant dose reductions while maintaining the overall cardiac risk classification. METHODS Forty-three patients (mean age, 61.8 ± 9.0 years; 40% male) underwent a clinically indicated CACS scan at 120kVp, as well as an additional CACS acquisition using an individualized tube voltage between 70 and 130kVp based on the ATVS selection (CARE-kV). Datasets of the additional CACS scans were reconstructed using a kV-Independent Algorithm that allows for calcium scoring without changing the weighting threshold of 130HU, regardless of the tube voltage chosen for image acquisition. Agatston scores and radiation dose derived from the different ATVS-based CACS studies were compared to the standard acquisition at 120kVp. RESULTS Thirteen patients displayed a score of 0 and were correctly identified with the ATVS protocol. Agatston scores derived from the standard 120kVp (median, 33.4; IQR, 0-289.7) and the patient-tailored kV-Independent protocol (median, 47.5; IQR, 0-287.5) showed no significant differences (p = 0.094). The intra-class correlation for Agatston scores derived from the two different protocols was excellent (ICC = 0.99). The mean dose-length-product was 29.8 ± 11.9 mGy × cm using the ATVS protocol and 31.7 ± 11.4 mGy × cm using the standard 120kVp protocol (p 400) using the patient-tailored protocol. CONCLUSIONS ATVS-based CACS, using a kV-Independent Algorithm, allows for high accuracy compared to the standard 120kVp scanning, while significantly reducing radiation dose parameters. KEY POINTS • ATVS allows for CT scanning with reduced radiation dose values. • KV-Independent CACS is feasible at any tube voltage between 70 and 130 kVp. • ATVS applied to kV-Independent CACS can significantly reduce the radiation dose.
Pooyan Sahbaee - One of the best experts on this subject based on the ideXlab platform.
-
individualized coronary calcium scoring at any tube voltage using a kv Independent reconstruction Algorithm
European Radiology, 2020Co-Authors: Vincenzo Vingiani, Andres F Abadia, Joseph U Schoepf, Andreas M Fischer, Akos Vargaszemes, Pooyan Sahbaee, Thomas Allmendinger, Dante A. Giovagnoli, Todd H Hudson, Riccardo MaranoAbstract:PURPOSE We prospectively investigate the feasibility of a patient specific automated tube voltage selection (ATVS)-based coronary artery calcium scoring (CACS) protocol, using a kV-Independent reconstruction Algorithm, to achieve significant dose reductions while maintaining the overall cardiac risk classification. METHODS Forty-three patients (mean age, 61.8 ± 9.0 years; 40% male) underwent a clinically indicated CACS scan at 120kVp, as well as an additional CACS acquisition using an individualized tube voltage between 70 and 130kVp based on the ATVS selection (CARE-kV). Datasets of the additional CACS scans were reconstructed using a kV-Independent Algorithm that allows for calcium scoring without changing the weighting threshold of 130HU, regardless of the tube voltage chosen for image acquisition. Agatston scores and radiation dose derived from the different ATVS-based CACS studies were compared to the standard acquisition at 120kVp. RESULTS Thirteen patients displayed a score of 0 and were correctly identified with the ATVS protocol. Agatston scores derived from the standard 120kVp (median, 33.4; IQR, 0-289.7) and the patient-tailored kV-Independent protocol (median, 47.5; IQR, 0-287.5) showed no significant differences (p = 0.094). The intra-class correlation for Agatston scores derived from the two different protocols was excellent (ICC = 0.99). The mean dose-length-product was 29.8 ± 11.9 mGy × cm using the ATVS protocol and 31.7 ± 11.4 mGy × cm using the standard 120kVp protocol (p 400) using the patient-tailored protocol. CONCLUSIONS ATVS-based CACS, using a kV-Independent Algorithm, allows for high accuracy compared to the standard 120kVp scanning, while significantly reducing radiation dose parameters. KEY POINTS • ATVS allows for CT scanning with reduced radiation dose values. • KV-Independent CACS is feasible at any tube voltage between 70 and 130 kVp. • ATVS applied to kV-Independent CACS can significantly reduce the radiation dose.
-
Individualized coronary calcium scoring at any tube voltage using a kV-Independent reconstruction Algorithm
European Radiology, 2020Co-Authors: Vincenzo Vingiani, Andres F Abadia, Andreas M Fischer, Pooyan Sahbaee, Thomas Allmendinger, U. Joseph Schoepf, Akos Varga-szemes, Dante A. Giovagnoli, H. Todd Hudson, Riccardo MaranoAbstract:Purpose We prospectively investigate the feasibility of a patient specific automated tube voltage selection (ATVS)-based coronary artery calcium scoring (CACS) protocol, using a kV-Independent reconstruction Algorithm, to achieve significant dose reductions while maintaining the overall cardiac risk classification. Methods Forty-three patients (mean age, 61.8 ± 9.0 years; 40% male) underwent a clinically indicated CACS scan at 120kVp, as well as an additional CACS acquisition using an individualized tube voltage between 70 and 130kVp based on the ATVS selection (CARE-kV). Datasets of the additional CACS scans were reconstructed using a kV-Independent Algorithm that allows for calcium scoring without changing the weighting threshold of 130HU, regardless of the tube voltage chosen for image acquisition. Agatston scores and radiation dose derived from the different ATVS-based CACS studies were compared to the standard acquisition at 120kVp. Results Thirteen patients displayed a score of 0 and were correctly identified with the ATVS protocol. Agatston scores derived from the standard 120kVp (median, 33.4; IQR, 0–289.7) and the patient-tailored kV-Independent protocol (median, 47.5; IQR, 0–287.5) showed no significant differences ( p = 0.094). The intra-class correlation for Agatston scores derived from the two different protocols was excellent (ICC = 0.99). The mean dose-length-product was 29.8 ± 11.9 mGy × cm using the ATVS protocol and 31.7 ± 11.4 mGy × cm using the standard 120kVp protocol ( p 400) using the patient-tailored protocol. Conclusions ATVS-based CACS, using a kV-Independent Algorithm, allows for high accuracy compared to the standard 120kVp scanning, while significantly reducing radiation dose parameters. Key Points • ATVS allows for CT scanning with reduced radiation dose values . • KV-Independent CACS is feasible at any tube voltage between 70 and 130 kVp. • ATVS applied to kV-Independent CACS can significantly reduce the radiation dose.
-
low kv coronary artery calcium scoring with tin filtration using a kv Independent reconstruction Algorithm
Journal of Cardiovascular Computed Tomography, 2020Co-Authors: Vincenzo Vingiani, Andres F Abadia, Joseph U Schoepf, Andreas M Fischer, Akos Vargaszemes, Pooyan Sahbaee, Thomas Allmendinger, Christian TescheAbstract:Abstract Purpose To investigate the accuracy of Agatston scoring and potential for radiation dose reduction of a coronary artery calcium scoring (CACS) CT protocol at 100 kV with tin filtration (Sn100kV) and kV-Independent iterative reconstruction, compared to standard 120 kV acquisitions. Materials and methods With IRB approval and in HIPAA compliance, 114 patients (61.8 ± 9.6 years; 66 men) underwent CACS using a standard 120 kV protocol and an additional Sn100kV CACS scan. The two datasets were reconstructed using a medium sharp convolution Algorithm and in addition the Sn100kV scans were reconstructed iteratively based on a kV-Independent Algorithm. Agatston scores and radiation dose values were compared between the Sn100kV and the standard 120 kV protocol. Results Median Agatston scores derived from the Sn100kV protocol with the kV-Independent Algorithm and the standard 120 kV were 21.4 (IQR, 0–173.8) and 24.7 (IQR, 0–171.1) respectively, with no significant differences (p=0.18). Agatston scores derived from the two different protocols had an excellent correlation (r = 0.99). The dose-length-product was 11.5 ± 4.1 mGy × cm using Sn100kV and 50.4 ± 24.9 mGy × cm using the standard 120 kV protocol (p 400) using the Sn100kV protocol. Conclusion CACS at Sn100kV using the kV-Independent iterative Algorithm is feasible and provides high accuracy when compared to standard 120 kV scanning. Furthermore, radiation dose can be significantly reduced for this screening application in a priori healthy individuals.
Thomas Allmendinger - One of the best experts on this subject based on the ideXlab platform.
-
individualized coronary calcium scoring at any tube voltage using a kv Independent reconstruction Algorithm
European Radiology, 2020Co-Authors: Vincenzo Vingiani, Andres F Abadia, Joseph U Schoepf, Andreas M Fischer, Akos Vargaszemes, Pooyan Sahbaee, Thomas Allmendinger, Dante A. Giovagnoli, Todd H Hudson, Riccardo MaranoAbstract:PURPOSE We prospectively investigate the feasibility of a patient specific automated tube voltage selection (ATVS)-based coronary artery calcium scoring (CACS) protocol, using a kV-Independent reconstruction Algorithm, to achieve significant dose reductions while maintaining the overall cardiac risk classification. METHODS Forty-three patients (mean age, 61.8 ± 9.0 years; 40% male) underwent a clinically indicated CACS scan at 120kVp, as well as an additional CACS acquisition using an individualized tube voltage between 70 and 130kVp based on the ATVS selection (CARE-kV). Datasets of the additional CACS scans were reconstructed using a kV-Independent Algorithm that allows for calcium scoring without changing the weighting threshold of 130HU, regardless of the tube voltage chosen for image acquisition. Agatston scores and radiation dose derived from the different ATVS-based CACS studies were compared to the standard acquisition at 120kVp. RESULTS Thirteen patients displayed a score of 0 and were correctly identified with the ATVS protocol. Agatston scores derived from the standard 120kVp (median, 33.4; IQR, 0-289.7) and the patient-tailored kV-Independent protocol (median, 47.5; IQR, 0-287.5) showed no significant differences (p = 0.094). The intra-class correlation for Agatston scores derived from the two different protocols was excellent (ICC = 0.99). The mean dose-length-product was 29.8 ± 11.9 mGy × cm using the ATVS protocol and 31.7 ± 11.4 mGy × cm using the standard 120kVp protocol (p 400) using the patient-tailored protocol. CONCLUSIONS ATVS-based CACS, using a kV-Independent Algorithm, allows for high accuracy compared to the standard 120kVp scanning, while significantly reducing radiation dose parameters. KEY POINTS • ATVS allows for CT scanning with reduced radiation dose values. • KV-Independent CACS is feasible at any tube voltage between 70 and 130 kVp. • ATVS applied to kV-Independent CACS can significantly reduce the radiation dose.
-
Individualized coronary calcium scoring at any tube voltage using a kV-Independent reconstruction Algorithm
European Radiology, 2020Co-Authors: Vincenzo Vingiani, Andres F Abadia, Andreas M Fischer, Pooyan Sahbaee, Thomas Allmendinger, U. Joseph Schoepf, Akos Varga-szemes, Dante A. Giovagnoli, H. Todd Hudson, Riccardo MaranoAbstract:Purpose We prospectively investigate the feasibility of a patient specific automated tube voltage selection (ATVS)-based coronary artery calcium scoring (CACS) protocol, using a kV-Independent reconstruction Algorithm, to achieve significant dose reductions while maintaining the overall cardiac risk classification. Methods Forty-three patients (mean age, 61.8 ± 9.0 years; 40% male) underwent a clinically indicated CACS scan at 120kVp, as well as an additional CACS acquisition using an individualized tube voltage between 70 and 130kVp based on the ATVS selection (CARE-kV). Datasets of the additional CACS scans were reconstructed using a kV-Independent Algorithm that allows for calcium scoring without changing the weighting threshold of 130HU, regardless of the tube voltage chosen for image acquisition. Agatston scores and radiation dose derived from the different ATVS-based CACS studies were compared to the standard acquisition at 120kVp. Results Thirteen patients displayed a score of 0 and were correctly identified with the ATVS protocol. Agatston scores derived from the standard 120kVp (median, 33.4; IQR, 0–289.7) and the patient-tailored kV-Independent protocol (median, 47.5; IQR, 0–287.5) showed no significant differences ( p = 0.094). The intra-class correlation for Agatston scores derived from the two different protocols was excellent (ICC = 0.99). The mean dose-length-product was 29.8 ± 11.9 mGy × cm using the ATVS protocol and 31.7 ± 11.4 mGy × cm using the standard 120kVp protocol ( p 400) using the patient-tailored protocol. Conclusions ATVS-based CACS, using a kV-Independent Algorithm, allows for high accuracy compared to the standard 120kVp scanning, while significantly reducing radiation dose parameters. Key Points • ATVS allows for CT scanning with reduced radiation dose values . • KV-Independent CACS is feasible at any tube voltage between 70 and 130 kVp. • ATVS applied to kV-Independent CACS can significantly reduce the radiation dose.
-
low kv coronary artery calcium scoring with tin filtration using a kv Independent reconstruction Algorithm
Journal of Cardiovascular Computed Tomography, 2020Co-Authors: Vincenzo Vingiani, Andres F Abadia, Joseph U Schoepf, Andreas M Fischer, Akos Vargaszemes, Pooyan Sahbaee, Thomas Allmendinger, Christian TescheAbstract:Abstract Purpose To investigate the accuracy of Agatston scoring and potential for radiation dose reduction of a coronary artery calcium scoring (CACS) CT protocol at 100 kV with tin filtration (Sn100kV) and kV-Independent iterative reconstruction, compared to standard 120 kV acquisitions. Materials and methods With IRB approval and in HIPAA compliance, 114 patients (61.8 ± 9.6 years; 66 men) underwent CACS using a standard 120 kV protocol and an additional Sn100kV CACS scan. The two datasets were reconstructed using a medium sharp convolution Algorithm and in addition the Sn100kV scans were reconstructed iteratively based on a kV-Independent Algorithm. Agatston scores and radiation dose values were compared between the Sn100kV and the standard 120 kV protocol. Results Median Agatston scores derived from the Sn100kV protocol with the kV-Independent Algorithm and the standard 120 kV were 21.4 (IQR, 0–173.8) and 24.7 (IQR, 0–171.1) respectively, with no significant differences (p=0.18). Agatston scores derived from the two different protocols had an excellent correlation (r = 0.99). The dose-length-product was 11.5 ± 4.1 mGy × cm using Sn100kV and 50.4 ± 24.9 mGy × cm using the standard 120 kV protocol (p 400) using the Sn100kV protocol. Conclusion CACS at Sn100kV using the kV-Independent iterative Algorithm is feasible and provides high accuracy when compared to standard 120 kV scanning. Furthermore, radiation dose can be significantly reduced for this screening application in a priori healthy individuals.
Andreas M Fischer - One of the best experts on this subject based on the ideXlab platform.
-
individualized coronary calcium scoring at any tube voltage using a kv Independent reconstruction Algorithm
European Radiology, 2020Co-Authors: Vincenzo Vingiani, Andres F Abadia, Joseph U Schoepf, Andreas M Fischer, Akos Vargaszemes, Pooyan Sahbaee, Thomas Allmendinger, Dante A. Giovagnoli, Todd H Hudson, Riccardo MaranoAbstract:PURPOSE We prospectively investigate the feasibility of a patient specific automated tube voltage selection (ATVS)-based coronary artery calcium scoring (CACS) protocol, using a kV-Independent reconstruction Algorithm, to achieve significant dose reductions while maintaining the overall cardiac risk classification. METHODS Forty-three patients (mean age, 61.8 ± 9.0 years; 40% male) underwent a clinically indicated CACS scan at 120kVp, as well as an additional CACS acquisition using an individualized tube voltage between 70 and 130kVp based on the ATVS selection (CARE-kV). Datasets of the additional CACS scans were reconstructed using a kV-Independent Algorithm that allows for calcium scoring without changing the weighting threshold of 130HU, regardless of the tube voltage chosen for image acquisition. Agatston scores and radiation dose derived from the different ATVS-based CACS studies were compared to the standard acquisition at 120kVp. RESULTS Thirteen patients displayed a score of 0 and were correctly identified with the ATVS protocol. Agatston scores derived from the standard 120kVp (median, 33.4; IQR, 0-289.7) and the patient-tailored kV-Independent protocol (median, 47.5; IQR, 0-287.5) showed no significant differences (p = 0.094). The intra-class correlation for Agatston scores derived from the two different protocols was excellent (ICC = 0.99). The mean dose-length-product was 29.8 ± 11.9 mGy × cm using the ATVS protocol and 31.7 ± 11.4 mGy × cm using the standard 120kVp protocol (p 400) using the patient-tailored protocol. CONCLUSIONS ATVS-based CACS, using a kV-Independent Algorithm, allows for high accuracy compared to the standard 120kVp scanning, while significantly reducing radiation dose parameters. KEY POINTS • ATVS allows for CT scanning with reduced radiation dose values. • KV-Independent CACS is feasible at any tube voltage between 70 and 130 kVp. • ATVS applied to kV-Independent CACS can significantly reduce the radiation dose.
-
Individualized coronary calcium scoring at any tube voltage using a kV-Independent reconstruction Algorithm
European Radiology, 2020Co-Authors: Vincenzo Vingiani, Andres F Abadia, Andreas M Fischer, Pooyan Sahbaee, Thomas Allmendinger, U. Joseph Schoepf, Akos Varga-szemes, Dante A. Giovagnoli, H. Todd Hudson, Riccardo MaranoAbstract:Purpose We prospectively investigate the feasibility of a patient specific automated tube voltage selection (ATVS)-based coronary artery calcium scoring (CACS) protocol, using a kV-Independent reconstruction Algorithm, to achieve significant dose reductions while maintaining the overall cardiac risk classification. Methods Forty-three patients (mean age, 61.8 ± 9.0 years; 40% male) underwent a clinically indicated CACS scan at 120kVp, as well as an additional CACS acquisition using an individualized tube voltage between 70 and 130kVp based on the ATVS selection (CARE-kV). Datasets of the additional CACS scans were reconstructed using a kV-Independent Algorithm that allows for calcium scoring without changing the weighting threshold of 130HU, regardless of the tube voltage chosen for image acquisition. Agatston scores and radiation dose derived from the different ATVS-based CACS studies were compared to the standard acquisition at 120kVp. Results Thirteen patients displayed a score of 0 and were correctly identified with the ATVS protocol. Agatston scores derived from the standard 120kVp (median, 33.4; IQR, 0–289.7) and the patient-tailored kV-Independent protocol (median, 47.5; IQR, 0–287.5) showed no significant differences ( p = 0.094). The intra-class correlation for Agatston scores derived from the two different protocols was excellent (ICC = 0.99). The mean dose-length-product was 29.8 ± 11.9 mGy × cm using the ATVS protocol and 31.7 ± 11.4 mGy × cm using the standard 120kVp protocol ( p 400) using the patient-tailored protocol. Conclusions ATVS-based CACS, using a kV-Independent Algorithm, allows for high accuracy compared to the standard 120kVp scanning, while significantly reducing radiation dose parameters. Key Points • ATVS allows for CT scanning with reduced radiation dose values . • KV-Independent CACS is feasible at any tube voltage between 70 and 130 kVp. • ATVS applied to kV-Independent CACS can significantly reduce the radiation dose.
-
low kv coronary artery calcium scoring with tin filtration using a kv Independent reconstruction Algorithm
Journal of Cardiovascular Computed Tomography, 2020Co-Authors: Vincenzo Vingiani, Andres F Abadia, Joseph U Schoepf, Andreas M Fischer, Akos Vargaszemes, Pooyan Sahbaee, Thomas Allmendinger, Christian TescheAbstract:Abstract Purpose To investigate the accuracy of Agatston scoring and potential for radiation dose reduction of a coronary artery calcium scoring (CACS) CT protocol at 100 kV with tin filtration (Sn100kV) and kV-Independent iterative reconstruction, compared to standard 120 kV acquisitions. Materials and methods With IRB approval and in HIPAA compliance, 114 patients (61.8 ± 9.6 years; 66 men) underwent CACS using a standard 120 kV protocol and an additional Sn100kV CACS scan. The two datasets were reconstructed using a medium sharp convolution Algorithm and in addition the Sn100kV scans were reconstructed iteratively based on a kV-Independent Algorithm. Agatston scores and radiation dose values were compared between the Sn100kV and the standard 120 kV protocol. Results Median Agatston scores derived from the Sn100kV protocol with the kV-Independent Algorithm and the standard 120 kV were 21.4 (IQR, 0–173.8) and 24.7 (IQR, 0–171.1) respectively, with no significant differences (p=0.18). Agatston scores derived from the two different protocols had an excellent correlation (r = 0.99). The dose-length-product was 11.5 ± 4.1 mGy × cm using Sn100kV and 50.4 ± 24.9 mGy × cm using the standard 120 kV protocol (p 400) using the Sn100kV protocol. Conclusion CACS at Sn100kV using the kV-Independent iterative Algorithm is feasible and provides high accuracy when compared to standard 120 kV scanning. Furthermore, radiation dose can be significantly reduced for this screening application in a priori healthy individuals.
