The Experts below are selected from a list of 549 Experts worldwide ranked by ideXlab platform
A R Nagui - One of the best experts on this subject based on the ideXlab platform.
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enhanced expression of cytokines may play a fundamental role in the mechanisms of immunologically mediated recurrent spontaneous Abortion
Acta Obstetricia et Gynecologica Scandinavica, 1997Co-Authors: Mohamed Shaarawy, A R NaguiAbstract:Objectives. To determine circulatory levels of 1L-1 β, TNFα, IFN-γ and Neopterin in immunologically mediated recurrent Abortion. Design. Blood samples were withdrawn from both groups of first trimester recurrent Abortion and controls for the determination of serum IL-lβ, TNFα, IFN-γ by the corresponding IRMA and serum neopterin by a double antibody RIA. Setting. Department of Obstetrics & Gynecology, Cairo University Hospitals. Patients. Thirty pregnant women in their first trimester who presented with Inevitable Abortion with history of at least 3 prior spontaneous consecutive Abortions, in addition to twenty-three pregnant women in their first trimester presented with their first miscarriage due to chromosomal anomalies (controls). Every attempt was made to eliminate the possible known contributing factors of recurrent Abortion except for the presence of cervical mucus sperm antibodies which were present in 24 out of 30 cases. Interventions. None. Results. Serum ILiβ, TNFα and IFN-γ levels of the aborti...
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original article enhanced expression of cytokines may play a fundamental role in the mechanisms of immunologically mediated recurrent spontaneous Abortion
Acta Obstetricia et Gynecologica Scandinavica, 1997Co-Authors: Mohamed Shaarawy, A R NaguiAbstract:Objectives. To determine circulatory levels of 1L-1 β, TNFα, IFN-γ and Neopterin in immunologically mediated recurrent Abortion. Design. Blood samples were withdrawn from both groups of first trimester recurrent Abortion and controls for the determination of serum IL-lβ, TNFα, IFN-γ by the corresponding IRMA and serum neopterin by a double antibody RIA. Setting. Department of Obstetrics & Gynecology, Cairo University Hospitals. Patients. Thirty pregnant women in their first trimester who presented with Inevitable Abortion with history of at least 3 prior spontaneous consecutive Abortions, in addition to twenty-three pregnant women in their first trimester presented with their first miscarriage due to chromosomal anomalies (controls). Every attempt was made to eliminate the possible known contributing factors of recurrent Abortion except for the presence of cervical mucus sperm antibodies which were present in 24 out of 30 cases. Interventions. None. Results. Serum ILiβ, TNFα and IFN-γ levels of the aborti...
Mohamed Shaarawy - One of the best experts on this subject based on the ideXlab platform.
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enhanced expression of cytokines may play a fundamental role in the mechanisms of immunologically mediated recurrent spontaneous Abortion
Acta Obstetricia et Gynecologica Scandinavica, 1997Co-Authors: Mohamed Shaarawy, A R NaguiAbstract:Objectives. To determine circulatory levels of 1L-1 β, TNFα, IFN-γ and Neopterin in immunologically mediated recurrent Abortion. Design. Blood samples were withdrawn from both groups of first trimester recurrent Abortion and controls for the determination of serum IL-lβ, TNFα, IFN-γ by the corresponding IRMA and serum neopterin by a double antibody RIA. Setting. Department of Obstetrics & Gynecology, Cairo University Hospitals. Patients. Thirty pregnant women in their first trimester who presented with Inevitable Abortion with history of at least 3 prior spontaneous consecutive Abortions, in addition to twenty-three pregnant women in their first trimester presented with their first miscarriage due to chromosomal anomalies (controls). Every attempt was made to eliminate the possible known contributing factors of recurrent Abortion except for the presence of cervical mucus sperm antibodies which were present in 24 out of 30 cases. Interventions. None. Results. Serum ILiβ, TNFα and IFN-γ levels of the aborti...
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original article enhanced expression of cytokines may play a fundamental role in the mechanisms of immunologically mediated recurrent spontaneous Abortion
Acta Obstetricia et Gynecologica Scandinavica, 1997Co-Authors: Mohamed Shaarawy, A R NaguiAbstract:Objectives. To determine circulatory levels of 1L-1 β, TNFα, IFN-γ and Neopterin in immunologically mediated recurrent Abortion. Design. Blood samples were withdrawn from both groups of first trimester recurrent Abortion and controls for the determination of serum IL-lβ, TNFα, IFN-γ by the corresponding IRMA and serum neopterin by a double antibody RIA. Setting. Department of Obstetrics & Gynecology, Cairo University Hospitals. Patients. Thirty pregnant women in their first trimester who presented with Inevitable Abortion with history of at least 3 prior spontaneous consecutive Abortions, in addition to twenty-three pregnant women in their first trimester presented with their first miscarriage due to chromosomal anomalies (controls). Every attempt was made to eliminate the possible known contributing factors of recurrent Abortion except for the presence of cervical mucus sperm antibodies which were present in 24 out of 30 cases. Interventions. None. Results. Serum ILiβ, TNFα and IFN-γ levels of the aborti...
Alka S. Gupta - One of the best experts on this subject based on the ideXlab platform.
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Comparative study of patients undergoing check curettage for first trimester incomplete and Inevitable Abortion under paracervical block versus no anesthesia
International Journal of Reproduction Contraception Obstetrics and Gynecology, 2016Co-Authors: Nihita Pandey, Alka S. GuptaAbstract:Background: The pain experienced during check curettage is due to the dilatation of the cervix, hence it can be hypothesized that in patients with a dilated internal os there should be no need for anesthesia. If it can be proven, then it would prove useful in cases where access to anesthesia is not available, such as primitive hospital set up, while also reducing the cost and complications of anesthesia. Methods: This study was a prospective randomized single blinded control trial conducted in a tertiary care centre over a period of 15 months with a sample size of 80 patients, 40 in group receiving paracervical block and 40 in group receiving no anesthesia. All patients with spontaneous first trimester incomplete and Inevitable Abortion were included and randomized in the two groups. Intraoperative vital parameters, vocalization, limb movement and demand for higher anesthesia were noted. Postoperative pain score was obtained based on the numeric rating scale. Results: The demand for higher anesthesia and satisfaction with procedure was comparable between the two groups (P> 0.05).The average pain score for patients receiving paracervical block was 1.13 and that for patients receiving no anesthesia was 1.79 (P
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comparative study of patients undergoing check curettage for first trimester incomplete and Inevitable Abortion under paracervical block versus no anesthesia
International journal of reproduction contraception obstetrics and gynecology, 2016Co-Authors: Nihita Pandey, Alka S. GuptaAbstract:Background: The pain experienced during check curettage is due to the dilatation of the cervix, hence it can be hypothesized that in patients with a dilated internal os there should be no need for anesthesia. If it can be proven, then it would prove useful in cases where access to anesthesia is not available, such as primitive hospital set up, while also reducing the cost and complications of anesthesia. Methods: This study was a prospective randomized single blinded control trial conducted in a tertiary care centre over a period of 15 months with a sample size of 80 patients, 40 in group receiving paracervical block and 40 in group receiving no anesthesia. All patients with spontaneous first trimester incomplete and Inevitable Abortion were included and randomized in the two groups. Intraoperative vital parameters, vocalization, limb movement and demand for higher anesthesia were noted. Postoperative pain score was obtained based on the numeric rating scale. Results: The demand for higher anesthesia and satisfaction with procedure was comparable between the two groups (P> 0.05).The average pain score for patients receiving paracervical block was 1.13 and that for patients receiving no anesthesia was 1.79 (P<0.05). Conclusions: The mean pain scores of both the groups were on the lower spectrum of the pain scale with no difference in demand for higher anesthesia. In primary set ups where facilities of anesthesia are not available, curettage can be performed safely without anesthesia, which can prove to be life-saving.
Zhou A - One of the best experts on this subject based on the ideXlab platform.
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Clinical significance of combining serum CA-125,β-hCG and progesterone in prediction outcome of threatened Abortion
Journal of Qiqihar University of Medicine, 2013Co-Authors: Zhou AAbstract:Objective To explore the clinical significance of combine serum CA-125,β-hCG and progesterone in prediction of outcomes of threatened Abortion. Methods Clinical data of 156 cases of early monovular pregnancy were divided into two groups: including 104 cases with threatened Abortion to pregnancy success( TAPS) and 52 cases with threatened Abortion to pregnancy failure( TAPF). At the same time,88normal pregnant women were selected as contrastive group. Serum CA-125,β-hCG and progesterone level were assayed with Chemiluminescence in all the cases. Results The serum CA-125 level of the Inevitable Abortion group was significantly higher than that of evitable Abortion group or contrastive group,while the β-hCG and progesterone level were significantly lower than those the other two groups at all times. The β-hCG and progesterone level interval 48 h of evitable Abortion group and contrastive group have a rising trend,growth in serumβ-hCG levels more than 60 in 97. 7% of the contrastive group and 92. 3% of the evitable Abortion group;The β-hCG level interval 48 h of only 21. 2% of the Inevitable Abortion group had a rising trend,progesterone level had a downtrend; The serum β-hCG and progesterone level fell at the same time in 78. 8% of the Inevitable Abortion group. Conclusions Joint monitoring of serum CA-125,β-hCG and progesterone,dynamic monitoring the variation trend of serum β-hCG and progesterone in 48h has important clinical significance in the early prediction of the prognosis of the threatened Abortion.
He Yuan-yuan - One of the best experts on this subject based on the ideXlab platform.
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Clinical value of monitoring serum CA-125、β-HCG and progesterone continuously in predicting outcome of threatened Abortion
2011Co-Authors: He Yuan-yuanAbstract:Objective To explore the value of monitoring serum CA-125、β-HCG and progesterone continuously in predicting the outcome of threatened Abortion.Methods The serum CA-125、β-HCG and progesterone levels of 96 patients with threatened Abortion were measured before treatment and 1,2,4 weeks after treatment.According to their outcomes,the patients were divided into Inevitable Abortion group and evitable Abortion group.At the same time,30 normal pregnant women were selected as contrastive group.Results The serum CA-125 level of the Inevitable Abortion group was significantly higher than that of evitable Abortion group or contrastive group,while theβ-HCG and progesterone level were significantly lower than those the other two groups at all times(P0.01).The serum CA-125 level of the evitable Abortion group was higher than that of contrastive group before treatment,while theβ-HCG and progesterone level was lower than that of contrastive group before treatment(P0.05).2 weeks after treatment,all serum levels of the evitable Abortion group and the contrastive group were no significant difference.Conclusions By a single serum CA125 level,we can predict the outcome of threatened Abortion fast and early.By combining dynamic observation of serum β-HCG and progesterone,we can improve the accuracy.