The Experts below are selected from a list of 126 Experts worldwide ranked by ideXlab platform
Matthew J Binnicker - One of the best experts on this subject based on the ideXlab platform.
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it is time to use treponema specific antibody Screening tests for diagnosis of syphilis
Journal of Clinical Microbiology, 2012Co-Authors: Michael J Loeffelholz, Matthew J BinnickerAbstract:Assays that detect treponema-specific antibodies, which are either automated or can be done as point-of-care tests, have been developed, some of which are FDA approved. These assays have the advantage of being easily performed and demonstrate high sensitivity, both key features of an Infectious Disease Screening test. As a result, many high-volume clinical laboratories have begun to offer a reverse syphilis testing algorithm where a treponema-specific test is used for Screening, followed by a nontreponemal test (i.e., rapid plasma reagin [RPR]) to assess Disease activity and treatment status. Concerns about physicians being able to understand and apply this new testing algorithm have been expressed (8). In this point-counterpoint, Michael Loeffelholz of the University of Texas Medical Branch at Galveston explains why his laboratory has adopted this reverse algorithmic approach. Matthew Binnicker of the Mayo Clinic, Rochester, MN, explains why the reverse algorithm may not be suitable for all clinical laboratories and every clinical situation.
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point counterpoint it is time to use treponema specific antibody Screening tests for diagnosis of syphilis
Journal of Clinical Microbiology, 2012Co-Authors: Michael J Loeffelholz, Matthew J BinnickerAbstract:ABSTRACT Assays that detect treponema-specific antibodies, which are either automated or can be done as point-of-care tests, have been developed, some of which are FDA approved. These assays have the advantage of being easily performed and demonstrate high sensitivity, both key features of an Infectious Disease Screening test. As a result, many high-volume clinical laboratories have begun to offer a reverse syphilis testing algorithm where a treponema-specific test is used for Screening, followed by a nontreponemal test (i.e., rapid plasma reagin [RPR]) to assess Disease activity and treatment status. Concerns about physicians being able to understand and apply this new testing algorithm have been expressed (8). In this point-counterpoint, Michael Loeffelholz of the University of Texas Medical Branch at Galveston explains why his laboratory has adopted this reverse algorithmic approach. Matthew Binnicker of the Mayo Clinic, Rochester, MN, explains why the reverse algorithm may not be suitable for all clinical laboratories and every clinical situation.
Michael J Loeffelholz - One of the best experts on this subject based on the ideXlab platform.
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it is time to use treponema specific antibody Screening tests for diagnosis of syphilis
Journal of Clinical Microbiology, 2012Co-Authors: Michael J Loeffelholz, Matthew J BinnickerAbstract:Assays that detect treponema-specific antibodies, which are either automated or can be done as point-of-care tests, have been developed, some of which are FDA approved. These assays have the advantage of being easily performed and demonstrate high sensitivity, both key features of an Infectious Disease Screening test. As a result, many high-volume clinical laboratories have begun to offer a reverse syphilis testing algorithm where a treponema-specific test is used for Screening, followed by a nontreponemal test (i.e., rapid plasma reagin [RPR]) to assess Disease activity and treatment status. Concerns about physicians being able to understand and apply this new testing algorithm have been expressed (8). In this point-counterpoint, Michael Loeffelholz of the University of Texas Medical Branch at Galveston explains why his laboratory has adopted this reverse algorithmic approach. Matthew Binnicker of the Mayo Clinic, Rochester, MN, explains why the reverse algorithm may not be suitable for all clinical laboratories and every clinical situation.
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point counterpoint it is time to use treponema specific antibody Screening tests for diagnosis of syphilis
Journal of Clinical Microbiology, 2012Co-Authors: Michael J Loeffelholz, Matthew J BinnickerAbstract:ABSTRACT Assays that detect treponema-specific antibodies, which are either automated or can be done as point-of-care tests, have been developed, some of which are FDA approved. These assays have the advantage of being easily performed and demonstrate high sensitivity, both key features of an Infectious Disease Screening test. As a result, many high-volume clinical laboratories have begun to offer a reverse syphilis testing algorithm where a treponema-specific test is used for Screening, followed by a nontreponemal test (i.e., rapid plasma reagin [RPR]) to assess Disease activity and treatment status. Concerns about physicians being able to understand and apply this new testing algorithm have been expressed (8). In this point-counterpoint, Michael Loeffelholz of the University of Texas Medical Branch at Galveston explains why his laboratory has adopted this reverse algorithmic approach. Matthew Binnicker of the Mayo Clinic, Rochester, MN, explains why the reverse algorithm may not be suitable for all clinical laboratories and every clinical situation.
Kayvan Bozorgmehr - One of the best experts on this subject based on the ideXlab platform.
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Infectious Disease health services for refugees and asylum seekers during a time of crisis a scoping study of six european union countries
Health Policy, 2019Co-Authors: Kayvan Bozorgmehr, Mariya Samuilova, Roumyana Petrovabenedict, Enrico Girardi, Pierluca Piselli, Alexander KentikelenisAbstract:Abstract Background Systematic information on Infectious Disease services provided to refugees and asylum seekers in the European Union (EU) is sparse. We conducted a scoping study of experts in six EU countries in order to map health system responses related to Infectious Disease prevention and control among refugees and asylum seekers. Methods We conducted 27 semi-structured in-depth interviews with first-line staff and health officials to collect information about existing guidelines and practices at each stage of reception in first-entry (Greece/Italy), transit (Croatia/Slovenia), and destination countries (Austria/Sweden). Thematic coding was used to perform a content analysis of interview material. Results Guidance on Infectious Disease Screening and health assessments lack standardisation across and—partly—within countries. Data collection on notifiable Infectious Diseases is mainly reported to be performed by national public health institutions, but is not stratified by migrant status. Health-related information is not transferred in a standardized way between facilities within a single country. International exchange of medical information between countries along the migration route is irregular. Services were reported to be fragmented, and respondents mentioned no specific coordination bodies beyond health authorities at different levels. Conclusion Infectious Disease health services provided to refugees and asylum seekers lack standardisation in health assessments, data collection, transfer of health-related information and (partly) coordination. This may negatively affect health system performance including public health emergency preparedness.
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Infectious Disease Screening in asylum seekers range coverage and economic evaluation in germany 2015
Eurosurveillance, 2017Co-Authors: Kayvan Bozorgmehr, Katharina Wahedi, Stefan Noest, Joachim Szecsenyi, Oliver RazumAbstract:Screening asylum seekers for Infectious Diseases is widely performed, but economic evaluations of such are scarce. We performed a policy analysis and economic evaluation of such Screening in Germany, and analysed the effect of Screening policies on cost differences between federal states. Of the 16 states, Screening was compulsory for tuberculosis (TB) in asylum seekers ≥ 16 years of age in all states as well as in children < 16 years of age and pregnant women in six states, hepatitis B and enteropathogens in three, syphilis in two and human immunodeficiency virus (HIV) in one state. Of 441,899 asylum seekers, 88.0% were screened for TB, 22.9% for enteropathogens, 16.9% for hepatitis B, 13.1% for syphilis and 11.3% for HIV. The total costs for compulsory Screening in 2015 were 10.3 million euros (EUR). Costs per case were highest for infections with Shigella spp. (80,200 EUR), Salmonella spp. (8,000 EUR), TB in those ≥ 16 years of age (5,300 EUR) and syphilis (1,150 EUR). States with extended Screening had per capita costs 2.84 times those of states that exclusively screened for TB in asylum seekers ≥ 16 years of age (p < 0.0001, 95% confidence interval (CI): 1.96–4.10). Screening practices in Germany entailed high costs; evidence-based approaches to Infectious Disease Screening are needed.
Alexander Kentikelenis - One of the best experts on this subject based on the ideXlab platform.
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Infectious Disease health services for refugees and asylum seekers during a time of crisis a scoping study of six european union countries
Health Policy, 2019Co-Authors: Kayvan Bozorgmehr, Mariya Samuilova, Roumyana Petrovabenedict, Enrico Girardi, Pierluca Piselli, Alexander KentikelenisAbstract:Abstract Background Systematic information on Infectious Disease services provided to refugees and asylum seekers in the European Union (EU) is sparse. We conducted a scoping study of experts in six EU countries in order to map health system responses related to Infectious Disease prevention and control among refugees and asylum seekers. Methods We conducted 27 semi-structured in-depth interviews with first-line staff and health officials to collect information about existing guidelines and practices at each stage of reception in first-entry (Greece/Italy), transit (Croatia/Slovenia), and destination countries (Austria/Sweden). Thematic coding was used to perform a content analysis of interview material. Results Guidance on Infectious Disease Screening and health assessments lack standardisation across and—partly—within countries. Data collection on notifiable Infectious Diseases is mainly reported to be performed by national public health institutions, but is not stratified by migrant status. Health-related information is not transferred in a standardized way between facilities within a single country. International exchange of medical information between countries along the migration route is irregular. Services were reported to be fragmented, and respondents mentioned no specific coordination bodies beyond health authorities at different levels. Conclusion Infectious Disease health services provided to refugees and asylum seekers lack standardisation in health assessments, data collection, transfer of health-related information and (partly) coordination. This may negatively affect health system performance including public health emergency preparedness.
Donna B Mak - One of the best experts on this subject based on the ideXlab platform.
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changing faces a review of Infectious Disease Screening of refugees by the migrant health unit western australia in 2003 and 2004
The Medical Journal of Australia, 2006Co-Authors: Jennifer A Martin, Donna B MakAbstract:Objective: To document demographic characteristics and prevalence of Infectious Diseases in refugees and humanitarian entrants attending the Migrant Health Unit (MHU) in Perth for health assessment from 1 January 2003 to 31 December 2004. Design: Retrospective case series. Participants: All refugees and humanitarian entrants arriving in Western Australia on subclass 200 and subclass 202 visas who were invited to attend the MHU. Main outcome measures: Demographic details, results of Mantoux tests, and blood and faecal tests for Infectious Diseases and parasites. Results: WA accepted 2781 refugee and humanitarian entrants in 2003 and 2004; 2617 were invited to attend the MHU, and 2111 (81%) actually attended for Screening. Over three-quarters arrived from Africa. Overall, 25% had a positive Mantoux test result, 5% were carriers of hepatitis B, and 5% had positive serological test results for syphilis. People arriving from sub-Saharan Africa had the highest prevalence of most Diseases, with 8% having malaria, 7% schistosomiasis, 5% hookworm, and 2% strongyloidiasis. Conclusion: Disease prevalence varied greatly between refugees from different countries and was particularly high in those arriving from sub-Saharan Africa, the origin of most of Australia's refugee and humanitarian entrants. These data support the need for refugees and humanitarian entrants from countries with high rates of Disease to have access to a comprehensive postarrival medical assessment and appropriate follow-up health care. Health services must provide beneficial and cost-effective services that protect the health of both individual refugees and the wider community.