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Hendrik Meyer-lueckel - One of the best experts on this subject based on the ideXlab platform.

  • Elution of Monomers from an Infiltrant Compared with Different Resin-Based Dental Materials.
    Oral health & preventive dentistry, 2020
    Co-Authors: Hendrik Meyer-lueckel, Christian Hartwig, Hans G Börner, Julian Lausch
    Abstract:

    PURPOSE Low-molecular weight residuals eluting from dental materials may contribute to local and systemic adverse effects. Therefore, the aim of the present study was to compare triethylene glycol dimethacrylate (TEGDMA)-based commercial Infiltrant with different conventional resin-based materials regarding their release of monomers. MATERIALS AND METHODS Cylindrical blocks (n = 10) of either two sealants (Helioseal, Delton FS+), a composite (EcuSphere), an adhesive (Teco) and an Infiltrant (Icon) were prepared. Additionally, 20 artificial lesions (depths ≥100 µm) were created in bovine enamel and after etching with phosphoric acid infiltrated with the Infiltrant. Except for 10 infiltrated lesions, all other specimens were polished. Each specimen was stored in 1 ml distilled water (elution medium) for 240 h. The medium was renewed in logarithmical divided time periods (4.5 min-76 h). RESULTS Total concentrations of eluted monomers within 240 h from the cylindrical specimens were 0.04-0.09 mg/ml (p >0.05; Mann-Whitney test). Unpolished infiltrated specimens showed significantly higher monomer concentrations compared to all other groups, whereas polishing of specimens resulted in significantly lower concentrations (p

  • Micro-filled resin infiltration of fissure caries lesions in vitro
    Journal of dentistry, 2016
    Co-Authors: Julian Lausch, Haitham Askar, Sebastian Paris, Hendrik Meyer-lueckel
    Abstract:

    Abstract Objectives The aim of this in vitro study was to evaluate three treatment modalities [Infiltrant resin (IR), micro-filled Infiltrant resin (MFIR), Infiltrant-sealant-combination (ISC)] regarding both their abilities to penetrate lesions differing in ICDAS-codes and to fill fissures and cavities. Materials and methods Extracted human molars (n = 90) showing fissure caries lesions with and without cavitations were etched with 15% hydrochloric acid (HCl) that was mixed with abrasives and a 15% HCl-solution (1:1). The etching gel was rubbed for 30 s within the fissure and, if eligible, within the cavity using a brush. After this pretreatment an Infiltrant (Icon; DMG; IR) or an Infiltrant mixed with microfillers (MFIR) was applied. ISC included the application of an Infiltrant followed by a fissure sealant (Helioseal; Ivoclar Vivadent) From each tooth slices showing a non-cavitated (based on ICDAS-2) or cavitated lesion part (based on ICDAS-3/5) were prepared. Lesion (LA) and penetration areas (PA) as well as the completeness of fissure and cavity filling were analyzed using dual staining and confocal laser scanning microscopy. Results Percentage penetration (PP) was calculated as 100 × PA/LA. PP [median (25th/75th)] did not differ significantly between IR [95 (86/100)%], MFIR [93 (62/100)%] or ISC [89 (67/97)%] (p > 0.05; Kruskal-Wallis test). All three materials filled about 90% of the dimensions of fissures and cavities (p > 0.05; Kruskal-Wallis test). Conclusion It can be concluded that MFIR seems to be suitable to fill fissures and cavities like a fissure sealant and that it penetrates fissure caries lesions similarly deep as the conventional Infiltrant after an experimental etching regime. Clinical significance The MFIR seems to combine advantages of the fissure sealing and the caries infiltration procedure.

  • Penetration of micro-filled Infiltrant resins into artificial caries lesions.
    Journal of dentistry, 2015
    Co-Authors: Haitham Askar, Hendrik Meyer-lueckel, Christof E. Dörfer, Julian Lausch, Sebastian Paris
    Abstract:

    Objectives Infiltrants are non-filled low-viscosity resins that have been developed to arrest lesion progression by penetrating into the porosities of non-cavitated lesions where they are hardened and arrest lesion progression. The addition of fillers to Infiltrant resin might combine the high penetrativity of the former with the better applicability of composite resins. The aim of the present study was to evaluate the penetration of different experimental micro-filled Infiltrant resins (MFIRs) into artificial enamel lesions. Methods An Infiltrant (Icon; DMG) was mixed with either one of three fillers [OF83: organic filler (83 μm), OF42: organic filler (42 μm) or GF0.7: glass filler (0.7 μm)] reaching 35, 45 and 55% filler content, respectively. In each of 180 bovine enamel specimens three artificial lesions were created; two lesions were etched for 5 s (37% H3PO4), leaving one lesion as control. Specimens were randomly allocated to 10 groups, in which either one of the MFIRs or the Infiltrant was applied onto the two etched lesions for either 5 s or 10 s (n = 18/group). Percentage of penetration (PP) was calculated and analysed. Results For both application times a significant influence of filler size but not of filler concentration on PP could be revealed (p 

  • Micro-hardness and mineral loss of enamel lesions after infiltration with various resins: influence of Infiltrant composition and application frequency in vitro
    Journal of dentistry, 2013
    Co-Authors: Sebastian Paris, Christof E. Dörfer, F. Schwendicke, S. Seddig, W.-d. Müller, Hendrik Meyer-lueckel
    Abstract:

    Abstract Objectives The aim of this in vitro study was to evaluate the influence of Infiltrant composition and application frequency on micro-hardness and lesion progression after resin infiltration of artificial enamel lesions. Methods In each of 100 bovine enamel samples, three artificial caries lesions were created (pH = 4.95, 50 days). After etching two of the lesions (37% phosphoric acid) specimens were randomly allocated to five Infiltrants (four experimental Infiltrants with different monomer and solvent compositions and penetration coefficients, and one commercial Infiltrant [Icon, DMG]). Lesions were then infiltrated and light-cured, and infiltration repeated afterwards for one of the lesions. Infiltrated samples were cut into halves, with one half being demineralised for further 50 days. Micro-hardness (VHN) and integrated mineral loss (Δ Z ) were evaluated at baseline and after second demineralisation. Repeated measures ANOVA and paired t -tests were used to analyse influence of material composition and application frequency on micro-hardness and lesion progression (integrated mineral loss difference ΔΔ Z ). Results Resin infiltration significantly increased micro-hardness and reduced lesion progression compared to untreated artificial lesions ( p t -test). Neither micro-hardness nor lesion progression were significantly influenced by material composition ( p  > 0.05, ANOVA). In contrast, twice application resulted in significantly increased micro-hardness and demineralisation resistance of infiltrated lesions ( p Conclusion Resin infiltration significantly improves micro-hardness and demineralisation resistance of enamel lesions; these effects are significantly enhanced if resins are applied twice. Experimental resins did not outperform the commercial Infiltrant. Clinical significance This in vitro study demonstrated that resin infiltration significantly increases both micro-hardness and demineralisation resistance of enamel caries lesions. Twice application of the Infiltrant seems to increase these effects. In contrast, the composition of the Infiltrant had no significant influence on investigated parameters.

  • Pretreatment of natural caries lesions affects penetration depth of Infiltrants in vitro
    Clinical oral investigations, 2012
    Co-Authors: Sebastian Paris, Vera Mendes Soviero, M. Schuch, Hendrik Meyer-lueckel
    Abstract:

    Objectives Limited evidence exists about the usefulness of ethanol or acetone application to desiccate caries lesions before resin infiltration. Therefore, this in vitro study aimed to compare the penetration depths (PD) of an Infiltrant (DMG, Germany) into natural caries lesions using various pretreatments.

Sebastian Paris - One of the best experts on this subject based on the ideXlab platform.

  • Micro-filled resin infiltration of fissure caries lesions in vitro
    Journal of dentistry, 2016
    Co-Authors: Julian Lausch, Haitham Askar, Sebastian Paris, Hendrik Meyer-lueckel
    Abstract:

    Abstract Objectives The aim of this in vitro study was to evaluate three treatment modalities [Infiltrant resin (IR), micro-filled Infiltrant resin (MFIR), Infiltrant-sealant-combination (ISC)] regarding both their abilities to penetrate lesions differing in ICDAS-codes and to fill fissures and cavities. Materials and methods Extracted human molars (n = 90) showing fissure caries lesions with and without cavitations were etched with 15% hydrochloric acid (HCl) that was mixed with abrasives and a 15% HCl-solution (1:1). The etching gel was rubbed for 30 s within the fissure and, if eligible, within the cavity using a brush. After this pretreatment an Infiltrant (Icon; DMG; IR) or an Infiltrant mixed with microfillers (MFIR) was applied. ISC included the application of an Infiltrant followed by a fissure sealant (Helioseal; Ivoclar Vivadent) From each tooth slices showing a non-cavitated (based on ICDAS-2) or cavitated lesion part (based on ICDAS-3/5) were prepared. Lesion (LA) and penetration areas (PA) as well as the completeness of fissure and cavity filling were analyzed using dual staining and confocal laser scanning microscopy. Results Percentage penetration (PP) was calculated as 100 × PA/LA. PP [median (25th/75th)] did not differ significantly between IR [95 (86/100)%], MFIR [93 (62/100)%] or ISC [89 (67/97)%] (p > 0.05; Kruskal-Wallis test). All three materials filled about 90% of the dimensions of fissures and cavities (p > 0.05; Kruskal-Wallis test). Conclusion It can be concluded that MFIR seems to be suitable to fill fissures and cavities like a fissure sealant and that it penetrates fissure caries lesions similarly deep as the conventional Infiltrant after an experimental etching regime. Clinical significance The MFIR seems to combine advantages of the fissure sealing and the caries infiltration procedure.

  • penetration of micro filled Infiltrant resins into artificial caries lesions
    Journal of Dentistry, 2015
    Co-Authors: Haitham Askar, Christof E. Dörfer, Julian Lausch, Hendrik Meyerlueckel, Sebastian Paris
    Abstract:

    Objectives Infiltrants are non-filled low-viscosity resins that have been developed to arrest lesion progression by penetrating into the porosities of non-cavitated lesions where they are hardened and arrest lesion progression. The addition of fillers to Infiltrant resin might combine the high penetrativity of the former with the better applicability of composite resins. The aim of the present study was to evaluate the penetration of different experimental micro-filled Infiltrant resins (MFIRs) into artificial enamel lesions. Methods An Infiltrant (Icon; DMG) was mixed with either one of three fillers [OF83: organic filler (83 μm), OF42: organic filler (42 μm) or GF0.7: glass filler (0.7 μm)] reaching 35, 45 and 55% filler content, respectively. In each of 180 bovine enamel specimens three artificial lesions were created; two lesions were etched for 5 s (37% H3PO4), leaving one lesion as control. Specimens were randomly allocated to 10 groups, in which either one of the MFIRs or the Infiltrant was applied onto the two etched lesions for either 5 s or 10 s (n = 18/group). Percentage of penetration (PP) was calculated and analysed. Results For both application times a significant influence of filler size but not of filler concentration on PP could be revealed (p < 0.05; two-way ANOVA). PP of MFIRs-OF42 was not significantly different from unfilled Infiltrant but significantly higher than those of OF83 and GF0.7 (p < 0.05; two-way ANOVA). Conclusions MFIRs-OF42 showed the ability to penetrate into artificial enamel caries lesions similar to the unfilled Infiltrant resin. Clinical significance MFIRs could provide a new micro-invasive treatment for small-cavitated lesions.

  • Penetration of micro-filled Infiltrant resins into artificial caries lesions.
    Journal of dentistry, 2015
    Co-Authors: Haitham Askar, Hendrik Meyer-lueckel, Christof E. Dörfer, Julian Lausch, Sebastian Paris
    Abstract:

    Objectives Infiltrants are non-filled low-viscosity resins that have been developed to arrest lesion progression by penetrating into the porosities of non-cavitated lesions where they are hardened and arrest lesion progression. The addition of fillers to Infiltrant resin might combine the high penetrativity of the former with the better applicability of composite resins. The aim of the present study was to evaluate the penetration of different experimental micro-filled Infiltrant resins (MFIRs) into artificial enamel lesions. Methods An Infiltrant (Icon; DMG) was mixed with either one of three fillers [OF83: organic filler (83 μm), OF42: organic filler (42 μm) or GF0.7: glass filler (0.7 μm)] reaching 35, 45 and 55% filler content, respectively. In each of 180 bovine enamel specimens three artificial lesions were created; two lesions were etched for 5 s (37% H3PO4), leaving one lesion as control. Specimens were randomly allocated to 10 groups, in which either one of the MFIRs or the Infiltrant was applied onto the two etched lesions for either 5 s or 10 s (n = 18/group). Percentage of penetration (PP) was calculated and analysed. Results For both application times a significant influence of filler size but not of filler concentration on PP could be revealed (p 

  • Micro-hardness and mineral loss of enamel lesions after infiltration with various resins: influence of Infiltrant composition and application frequency in vitro
    Journal of dentistry, 2013
    Co-Authors: Sebastian Paris, Christof E. Dörfer, F. Schwendicke, S. Seddig, W.-d. Müller, Hendrik Meyer-lueckel
    Abstract:

    Abstract Objectives The aim of this in vitro study was to evaluate the influence of Infiltrant composition and application frequency on micro-hardness and lesion progression after resin infiltration of artificial enamel lesions. Methods In each of 100 bovine enamel samples, three artificial caries lesions were created (pH = 4.95, 50 days). After etching two of the lesions (37% phosphoric acid) specimens were randomly allocated to five Infiltrants (four experimental Infiltrants with different monomer and solvent compositions and penetration coefficients, and one commercial Infiltrant [Icon, DMG]). Lesions were then infiltrated and light-cured, and infiltration repeated afterwards for one of the lesions. Infiltrated samples were cut into halves, with one half being demineralised for further 50 days. Micro-hardness (VHN) and integrated mineral loss (Δ Z ) were evaluated at baseline and after second demineralisation. Repeated measures ANOVA and paired t -tests were used to analyse influence of material composition and application frequency on micro-hardness and lesion progression (integrated mineral loss difference ΔΔ Z ). Results Resin infiltration significantly increased micro-hardness and reduced lesion progression compared to untreated artificial lesions ( p t -test). Neither micro-hardness nor lesion progression were significantly influenced by material composition ( p  > 0.05, ANOVA). In contrast, twice application resulted in significantly increased micro-hardness and demineralisation resistance of infiltrated lesions ( p Conclusion Resin infiltration significantly improves micro-hardness and demineralisation resistance of enamel lesions; these effects are significantly enhanced if resins are applied twice. Experimental resins did not outperform the commercial Infiltrant. Clinical significance This in vitro study demonstrated that resin infiltration significantly increases both micro-hardness and demineralisation resistance of enamel caries lesions. Twice application of the Infiltrant seems to increase these effects. In contrast, the composition of the Infiltrant had no significant influence on investigated parameters.

  • Pretreatment of natural caries lesions affects penetration depth of Infiltrants in vitro
    Clinical oral investigations, 2012
    Co-Authors: Sebastian Paris, Vera Mendes Soviero, M. Schuch, Hendrik Meyer-lueckel
    Abstract:

    Objectives Limited evidence exists about the usefulness of ethanol or acetone application to desiccate caries lesions before resin infiltration. Therefore, this in vitro study aimed to compare the penetration depths (PD) of an Infiltrant (DMG, Germany) into natural caries lesions using various pretreatments.

Heitor Marques Honório - One of the best experts on this subject based on the ideXlab platform.

  • Experimental self-etching resin Infiltrants on the treatment of simulated carious white spot lesions.
    Journal of the mechanical behavior of biomedical materials, 2020
    Co-Authors: Linda Wang, Maria Cristina Carvalho De Almendra Freitas, Daniela Rios, Anuradha Prakki, Victor Mosquim, Alejandra Hortencia Miranda González, Heitor Marques Honório
    Abstract:

    OBJECTIVES To evaluate the penetration depth (μm) of experimental resin Infiltrants containing different percentages of triethylene glycol dimethacrylate (TEGDMA) and phosphoric acid 2-hydroxyethyl methacrylate ester (PAM) in artificial carious white spot lesions (WSL). METHODS WSL were produced in 65 bovine flat enamel specimens by pH cycling protocol, which were treated with either Icon (control) or experimental acidic Infiltrants based on different percentages of TEGDMA and PAM monomers (acidic), and their association or not with previous acid-etching with phosphoric acid. Ten readings using Confocal Laser Scanning Microscopy were conducted on each specimen and the penetration depth was calculated from the surface until the deepest point with the fluorescent dye Rhodamine B (0.02 mg/mL). The pH and the viscosity of the experimental Infiltrants were also tested. Data were statistically analyzed with two-way ANOVA and Tukey tests (α 

  • In vitro effect of a resin Infiltrant on different artificial caries-like enamel lesions.
    Archives of oral biology, 2018
    Co-Authors: Maria Cristina Carvalho De Almendra Freitas, Larissa Vasconcellos Nunes, Lívia Picchi Comar, Daniela Rios, Ana Carolina Magalhães, Heitor Marques Honório, Linda Wang
    Abstract:

    Abstract Objectives A resin Infiltrant was employed for the treatment of active white spot lesions due to its ability to penetrate into the enamel pores and prevent the progression of the lesion. However, limited information is available about its mechanical effect on different artificial enamel lesions as well as on its resistance to further demineralization. Therefore, this study aimed to evaluate the effects of the Icon® Infiltrant on different artificial caries-like enamel lesions and its resistance to new acid challenges. Design Artificial lesions were produced in bovine enamel using three different protocols (demineralization/remineralization cycling, DE-RE; 8% methylcellulose gel, MC; and methyl ethyl diphosphonate solution, MHDP; n = 13). The specimens were treated with Icon® and subjected to a new acid challenge using DE-RE cycling. The surface and cross-sectional hardness were evaluated in sound, demineralized, treated and further demineralized enamel areas. Data were statistically analyzed using ANOVA and Tukey’s test (p  Results All of the demineralizing protocols produced subsurface artificial caries lesions. The Infiltrant was able to partially recover the surface hardness and prevent further surface hardness loss in enamel previously demineralized using the DE-RE and MHDP protocols. In regard to cross-sectional hardness, no positive effect was found. Conclusions The effect of the Infiltrant depends on the type of lesion created in vitro, and its action is limited to the lesion surface.

Linda Wang - One of the best experts on this subject based on the ideXlab platform.

  • Experimental self-etching resin Infiltrants on the treatment of simulated carious white spot lesions.
    Journal of the mechanical behavior of biomedical materials, 2020
    Co-Authors: Linda Wang, Maria Cristina Carvalho De Almendra Freitas, Daniela Rios, Anuradha Prakki, Victor Mosquim, Alejandra Hortencia Miranda González, Heitor Marques Honório
    Abstract:

    OBJECTIVES To evaluate the penetration depth (μm) of experimental resin Infiltrants containing different percentages of triethylene glycol dimethacrylate (TEGDMA) and phosphoric acid 2-hydroxyethyl methacrylate ester (PAM) in artificial carious white spot lesions (WSL). METHODS WSL were produced in 65 bovine flat enamel specimens by pH cycling protocol, which were treated with either Icon (control) or experimental acidic Infiltrants based on different percentages of TEGDMA and PAM monomers (acidic), and their association or not with previous acid-etching with phosphoric acid. Ten readings using Confocal Laser Scanning Microscopy were conducted on each specimen and the penetration depth was calculated from the surface until the deepest point with the fluorescent dye Rhodamine B (0.02 mg/mL). The pH and the viscosity of the experimental Infiltrants were also tested. Data were statistically analyzed with two-way ANOVA and Tukey tests (α 

  • In vitro effect of a resin Infiltrant on different artificial caries-like enamel lesions.
    Archives of oral biology, 2018
    Co-Authors: Maria Cristina Carvalho De Almendra Freitas, Larissa Vasconcellos Nunes, Lívia Picchi Comar, Daniela Rios, Ana Carolina Magalhães, Heitor Marques Honório, Linda Wang
    Abstract:

    Abstract Objectives A resin Infiltrant was employed for the treatment of active white spot lesions due to its ability to penetrate into the enamel pores and prevent the progression of the lesion. However, limited information is available about its mechanical effect on different artificial enamel lesions as well as on its resistance to further demineralization. Therefore, this study aimed to evaluate the effects of the Icon® Infiltrant on different artificial caries-like enamel lesions and its resistance to new acid challenges. Design Artificial lesions were produced in bovine enamel using three different protocols (demineralization/remineralization cycling, DE-RE; 8% methylcellulose gel, MC; and methyl ethyl diphosphonate solution, MHDP; n = 13). The specimens were treated with Icon® and subjected to a new acid challenge using DE-RE cycling. The surface and cross-sectional hardness were evaluated in sound, demineralized, treated and further demineralized enamel areas. Data were statistically analyzed using ANOVA and Tukey’s test (p  Results All of the demineralizing protocols produced subsurface artificial caries lesions. The Infiltrant was able to partially recover the surface hardness and prevent further surface hardness loss in enamel previously demineralized using the DE-RE and MHDP protocols. In regard to cross-sectional hardness, no positive effect was found. Conclusions The effect of the Infiltrant depends on the type of lesion created in vitro, and its action is limited to the lesion surface.

Vera Mendes Soviero - One of the best experts on this subject based on the ideXlab platform.