The Experts below are selected from a list of 5424 Experts worldwide ranked by ideXlab platform
P Verma - One of the best experts on this subject based on the ideXlab platform.
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assessing software reliability performance under highly critical but Infrequent Event occurrences
International Symposium on Software Reliability Engineering, 1997Co-Authors: M S Alam, W H Chen, W K Ehrlich, M E Engel, D A Kropfl, P VermaAbstract:Operational testing is expensive and time-consuming in applications with highly critical but Infrequent Event occurrences, and procedures are needed for obtaining valid software reliability estimates. Two such procedures are accelerated stress testing and experimental design techniques. Examples of accelerated stress in software include: a higher request arrival rate, increasing data traffic "burstiness", and so on. Furthermore, when the software is tested by executing the system under emergency conditions or exception Events, it is critical that experimental design techniques are used to account for "carry-over" effects in failure performance. An application of software reliability testing of a telecommunication system node controller is used to describe the issues and our overall approach to software reliability assessment. The reliability projections based on our approach are compared to reliability estimates derived analytically and through simulation. Our results suggest that these statistical techniques are useful techniques for measuring reliability performance under critical Events that have a low probability of occurrence.
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ISSRE - Assessing software reliability performance under highly critical but Infrequent Event occurrences
Proceedings The Eighth International Symposium on Software Reliability Engineering, 1Co-Authors: M S Alam, W H Chen, W K Ehrlich, M E Engel, D A Kropfl, P VermaAbstract:Operational testing is expensive and time-consuming in applications with highly critical but Infrequent Event occurrences, and procedures are needed for obtaining valid software reliability estimates. Two such procedures are accelerated stress testing and experimental design techniques. Examples of accelerated stress in software include: a higher request arrival rate, increasing data traffic "burstiness", and so on. Furthermore, when the software is tested by executing the system under emergency conditions or exception Events, it is critical that experimental design techniques are used to account for "carry-over" effects in failure performance. An application of software reliability testing of a telecommunication system node controller is used to describe the issues and our overall approach to software reliability assessment. The reliability projections based on our approach are compared to reliability estimates derived analytically and through simulation. Our results suggest that these statistical techniques are useful techniques for measuring reliability performance under critical Events that have a low probability of occurrence.
Jy Sung - One of the best experts on this subject based on the ideXlab platform.
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Somatic β-catenin mutation in gastric carcinoma – an Infrequent Event that is not specific for microsatellite instability
Cancer letters, 2001Co-Authors: Joanna Hung-man Tong, James Y.w. Lau, Tin L. Lee, W.k. Leung, Nelson L.s. Tang, Fkl Chan, Jy SungAbstract:We screened 90 cases of gastric carcinoma (GCA) samples for β-catenin exon 3 mutation and assessed its possible relationship with microsatellite instability (MSI). Three mutations were detected in two samples, including a single mutation in an intestinal type and double mutations in a diffuse type GCA. One of the mutations found in the diffuse type GCA sample was a non-sense mutation at codon 68 (CAG→TAG). This novel mutation was predicted to disrupt the binding of β-catenin to α-catenin and may be related to the diffuse type morphology. The other two mutations were missense mutations involved or related to the GSK-3β phosphorylation site, which have been reported previously. No MSI can be demonstrated in the two cases with β-catenin mutation. Our results suggested that β-catenin mutation was Infrequent in GCA and appeared not specific for MSI.
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somatic β catenin mutation in gastric carcinoma an Infrequent Event that is not specific for microsatellite instability
Cancer Letters, 2001Co-Authors: Joanna Hung-man Tong, James Y.w. Lau, Tin L. Lee, W.k. Leung, Nelson L.s. Tang, Fkl Chan, Jy Sung, S C S ChungAbstract:We screened 90 cases of gastric carcinoma (GCA) samples for β-catenin exon 3 mutation and assessed its possible relationship with microsatellite instability (MSI). Three mutations were detected in two samples, including a single mutation in an intestinal type and double mutations in a diffuse type GCA. One of the mutations found in the diffuse type GCA sample was a non-sense mutation at codon 68 (CAG→TAG). This novel mutation was predicted to disrupt the binding of β-catenin to α-catenin and may be related to the diffuse type morphology. The other two mutations were missense mutations involved or related to the GSK-3β phosphorylation site, which have been reported previously. No MSI can be demonstrated in the two cases with β-catenin mutation. Our results suggested that β-catenin mutation was Infrequent in GCA and appeared not specific for MSI.
Joanna Hung-man Tong - One of the best experts on this subject based on the ideXlab platform.
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Somatic β-catenin mutation in gastric carcinoma – an Infrequent Event that is not specific for microsatellite instability
Cancer letters, 2001Co-Authors: Joanna Hung-man Tong, James Y.w. Lau, Tin L. Lee, W.k. Leung, Nelson L.s. Tang, Fkl Chan, Jy SungAbstract:We screened 90 cases of gastric carcinoma (GCA) samples for β-catenin exon 3 mutation and assessed its possible relationship with microsatellite instability (MSI). Three mutations were detected in two samples, including a single mutation in an intestinal type and double mutations in a diffuse type GCA. One of the mutations found in the diffuse type GCA sample was a non-sense mutation at codon 68 (CAG→TAG). This novel mutation was predicted to disrupt the binding of β-catenin to α-catenin and may be related to the diffuse type morphology. The other two mutations were missense mutations involved or related to the GSK-3β phosphorylation site, which have been reported previously. No MSI can be demonstrated in the two cases with β-catenin mutation. Our results suggested that β-catenin mutation was Infrequent in GCA and appeared not specific for MSI.
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somatic β catenin mutation in gastric carcinoma an Infrequent Event that is not specific for microsatellite instability
Cancer Letters, 2001Co-Authors: Joanna Hung-man Tong, James Y.w. Lau, Tin L. Lee, W.k. Leung, Nelson L.s. Tang, Fkl Chan, Jy Sung, S C S ChungAbstract:We screened 90 cases of gastric carcinoma (GCA) samples for β-catenin exon 3 mutation and assessed its possible relationship with microsatellite instability (MSI). Three mutations were detected in two samples, including a single mutation in an intestinal type and double mutations in a diffuse type GCA. One of the mutations found in the diffuse type GCA sample was a non-sense mutation at codon 68 (CAG→TAG). This novel mutation was predicted to disrupt the binding of β-catenin to α-catenin and may be related to the diffuse type morphology. The other two mutations were missense mutations involved or related to the GSK-3β phosphorylation site, which have been reported previously. No MSI can be demonstrated in the two cases with β-catenin mutation. Our results suggested that β-catenin mutation was Infrequent in GCA and appeared not specific for MSI.
M S Alam - One of the best experts on this subject based on the ideXlab platform.
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assessing software reliability performance under highly critical but Infrequent Event occurrences
International Symposium on Software Reliability Engineering, 1997Co-Authors: M S Alam, W H Chen, W K Ehrlich, M E Engel, D A Kropfl, P VermaAbstract:Operational testing is expensive and time-consuming in applications with highly critical but Infrequent Event occurrences, and procedures are needed for obtaining valid software reliability estimates. Two such procedures are accelerated stress testing and experimental design techniques. Examples of accelerated stress in software include: a higher request arrival rate, increasing data traffic "burstiness", and so on. Furthermore, when the software is tested by executing the system under emergency conditions or exception Events, it is critical that experimental design techniques are used to account for "carry-over" effects in failure performance. An application of software reliability testing of a telecommunication system node controller is used to describe the issues and our overall approach to software reliability assessment. The reliability projections based on our approach are compared to reliability estimates derived analytically and through simulation. Our results suggest that these statistical techniques are useful techniques for measuring reliability performance under critical Events that have a low probability of occurrence.
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ISSRE - Assessing software reliability performance under highly critical but Infrequent Event occurrences
Proceedings The Eighth International Symposium on Software Reliability Engineering, 1Co-Authors: M S Alam, W H Chen, W K Ehrlich, M E Engel, D A Kropfl, P VermaAbstract:Operational testing is expensive and time-consuming in applications with highly critical but Infrequent Event occurrences, and procedures are needed for obtaining valid software reliability estimates. Two such procedures are accelerated stress testing and experimental design techniques. Examples of accelerated stress in software include: a higher request arrival rate, increasing data traffic "burstiness", and so on. Furthermore, when the software is tested by executing the system under emergency conditions or exception Events, it is critical that experimental design techniques are used to account for "carry-over" effects in failure performance. An application of software reliability testing of a telecommunication system node controller is used to describe the issues and our overall approach to software reliability assessment. The reliability projections based on our approach are compared to reliability estimates derived analytically and through simulation. Our results suggest that these statistical techniques are useful techniques for measuring reliability performance under critical Events that have a low probability of occurrence.
S C S Chung - One of the best experts on this subject based on the ideXlab platform.
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somatic β catenin mutation in gastric carcinoma an Infrequent Event that is not specific for microsatellite instability
Cancer Letters, 2001Co-Authors: Joanna Hung-man Tong, James Y.w. Lau, Tin L. Lee, W.k. Leung, Nelson L.s. Tang, Fkl Chan, Jy Sung, S C S ChungAbstract:We screened 90 cases of gastric carcinoma (GCA) samples for β-catenin exon 3 mutation and assessed its possible relationship with microsatellite instability (MSI). Three mutations were detected in two samples, including a single mutation in an intestinal type and double mutations in a diffuse type GCA. One of the mutations found in the diffuse type GCA sample was a non-sense mutation at codon 68 (CAG→TAG). This novel mutation was predicted to disrupt the binding of β-catenin to α-catenin and may be related to the diffuse type morphology. The other two mutations were missense mutations involved or related to the GSK-3β phosphorylation site, which have been reported previously. No MSI can be demonstrated in the two cases with β-catenin mutation. Our results suggested that β-catenin mutation was Infrequent in GCA and appeared not specific for MSI.