The Experts below are selected from a list of 57426 Experts worldwide ranked by ideXlab platform
Alexander M Binshtok - One of the best experts on this subject based on the ideXlab platform.
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chronic pain related remodeling of cerebral cortex pain memory a possible target for treatment of chronic pain
Pain management, 2013Co-Authors: Avigail Lithwick, Shaya Lev, Alexander M BinshtokAbstract:SUMMARY Chronic pain is a major health problem worldwide, yet its management is nonspecific and often insufficient. In order to be able to alleviate chronic pain, it is crucial to understand the profound and comprehensive mechanisms by which chronic pain is triggered and processed in higher brain areas. Painful stimuli are processed by an intricate axis of peripheral and central components. Adding to the Inherent Complexity, the system is highly dynamic, undergoing constant plastic changes that often lead to perpetuation of pain. Given the key role that the cerebral cortex plays in sensory perception, understanding pain-related changes in cortical areas allocated to pain sensation is crucial. This review aims to summarize present research on pain-related plastic changes in the cerebral cortex.
Avigail Lithwick - One of the best experts on this subject based on the ideXlab platform.
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chronic pain related remodeling of cerebral cortex pain memory a possible target for treatment of chronic pain
Pain management, 2013Co-Authors: Avigail Lithwick, Shaya Lev, Alexander M BinshtokAbstract:SUMMARY Chronic pain is a major health problem worldwide, yet its management is nonspecific and often insufficient. In order to be able to alleviate chronic pain, it is crucial to understand the profound and comprehensive mechanisms by which chronic pain is triggered and processed in higher brain areas. Painful stimuli are processed by an intricate axis of peripheral and central components. Adding to the Inherent Complexity, the system is highly dynamic, undergoing constant plastic changes that often lead to perpetuation of pain. Given the key role that the cerebral cortex plays in sensory perception, understanding pain-related changes in cortical areas allocated to pain sensation is crucial. This review aims to summarize present research on pain-related plastic changes in the cerebral cortex.
Helen J Cooper - One of the best experts on this subject based on the ideXlab platform.
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higher energy collision dissociation hcd product ion triggered electron transfer dissociation etd mass spectrometry for the analysis of n linked glycoproteins
Journal of Proteome Research, 2012Co-Authors: Charandeep Singh, Cleidiane G Zampronio, Andrew J Creese, Helen J CooperAbstract:Large scale mass spectrometry analysis of N-linked glycopeptides is complicated by the Inherent Complexity of the glycan structures. Here, we evaluate a mass spectrometry approach for the targeted ...
Jonas Bergquist - One of the best experts on this subject based on the ideXlab platform.
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prediction of chromatographic retention and protein identification in liquid chromatography mass spectrometry
Analytical Chemistry, 2002Co-Authors: Magnus Palmblad, Margareta Ramstrom, Karin E Markides, P Hakansson, Jonas BergquistAbstract:Liquid chromatography coupled on- or off-line with mass spectrometry is rapidly advancing as a tool in proteomics capable of dealing with the Inherent Complexity in biology and complementing conventional approaches based on two-dimensional gel electrophoresis. Proteins can be identified by proteolytic digestion and peptide mass fingerprinting or by searching databases using short-sequence tags generated by tandem mass spectrometry. This paper shows that information on the chromatographic behavior of peptides can assist protein identification by peptide mass fingerprinting in liquid chromatography/mass spectrometry. This additional information is significant and already available at no extra experimental cost.
Bonnie Simpson - One of the best experts on this subject based on the ideXlab platform.
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understanding the Inherent Complexity of sustainable consumption a social cognitive framework
Journal of Business Research, 2013Co-Authors: Marcus Phipps, Lucie K Ozanne, Michael G Luchs, Saroja Subrahmanyan, Sommer Kapitan, Jesse R Catlin, Roland Gau, Rebecca Walker Naylor, Randall L Rose, Bonnie SimpsonAbstract:Abstract This article explores the potential of a theoretical framework, based on social cognitive theory (SCT), to inspire future research into sustainable consumption. The SCT framework provides a dynamic perspective on sustainable consumption through exploring the interactive nature of personal, environmental and behavioral factors of consumption. The SCT framework, which builds on prior theoretical models of sustainable consumption, incorporates the concept of reciprocal determinism, wherein personal, environmental and behavioral factors create a feedback loop to influence each other. Two examples, toy sharing in New Zealand and water conservation in Australia, illustrate the dynamic nature of sustainable consumption and the potential of an SCT based framework to provide a more nuanced view of behavioral change in this context. From these two examples, several ideas for future research emerge to help illustrate the potential of SCT to inform and inspire the next wave of research on sustainable consumption.