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Einar Thorsen - One of the best experts on this subject based on the ideXlab platform.

  • Peak oxygen uptake and breathing pattern in COPD patients – a four-year longitudinal study
    BMC Pulmonary Medicine, 2015
    Co-Authors: Bente Frisk, Jon A. Hardie, Birgitte Espehaug, Liv I. Strand, Rolf Moe-nilssen, Tomas M. L. Eagan, Per S. Bakke, Einar Thorsen
    Abstract:

    Background Activities of daily living in patients with chronic obstructive pulmonary disease (COPD) are limited by exertional dyspnea and reduced exercise capacity. The aims of the study were to examine longitudinal changes in peak oxygen uptake (V̇O_2peak), peak minute ventilation (V̇_Epeak) and breathing pattern over four years in a group of COPD patients, and to examine potential explanatory variables of change. Methods This longitudinal study included 63 COPD patients, aged 44-75 years, with a mean forced expiratory Volume in one second (FEV_1) at baseline of 51 % of predicted (SD = 14). The patients performed two cardiopulmonary exercise tests (CPETs) on treadmill 4.5 years apart. The relationship between changes in V̇O_2peak and V̇_Epeak and possible explanatory variables, including dynamic lung Volumes and Inspiratory capacity (IC), were analysed by multivariate linear regression analysis. The breathing pattern in terms of the relationship between minute ventilation (V̇_E) and tidal Volume (V_T) was described by a quadratic equation, V_T = a + b∙V̇_E + c∙V̇_E^2, for each test. The V_Tmax was calculated from the individual quadratic relationships, and was the point where the first derivative of the quadratic equation was zero. The mean changes in the curve parameters (CPET2 minus CPET1) and V_Tmax were analysed by bivariate and multivariate linear regression analyses with age, sex, height, changes in weight, lung function, IC and Inspiratory Reserve Volume as possible explanatory variables. Results Significant reductions in V̇O_2peak ( p  

  • Peak oxygen uptake and breathing pattern in COPD patients – A four year longitudinal study
    BMC Pulmonary Medicine, 2015
    Co-Authors: Bente Frisk, Jon A. Hardie, Birgitte Espehaug, Liv I. Strand, Rolf Moe-nilssen, Tomas M. L. Eagan, Per Bakke, Einar Thorsen
    Abstract:

    Activities of daily living in patients with chronic obstructive pulmonary disease (COPD) are limited by exertional dyspnea and reduced exercise capacity. The aims of the study were to examine longitudinal changes in peak oxygen uptake (VO2peak), peak minute ventilation (VEpeak) and breathing pattern over four years in a group of COPD patients, and to examine potential explanatory variables of change. This longitudinal study included 63 COPD patients, aged 44-75 years, with a mean forced expiratory Volume in one second (FEV1) at baseline of 51 % of predicted (SD = 14). The patients performed two cardiopulmonary exercise tests (CPETs) on treadmill 4.5 years apart. The relationship between changes in VO2peak and VEpeak and possible explanatory variables, including dynamic lung Volumes and Inspiratory capacity (IC), were analysed by multivariate linear regression analysis. The breathing pattern in terms of the relationship between minute ventilation (VE) and tidal Volume (VT) was described by a quadratic equation, VT = a + b∙VE + c∙VE2, for each test. The VTmax was calculated from the individual quadratic relationships, and was the point where the first derivative of the quadratic equation was zero. The mean changes in the curve parameters (CPET2 minus CPET1) and VTmax were analysed by bivariate and multivariate linear regression analyses with age, sex, height, changes in weight, lung function, IC and Inspiratory Reserve Volume as possible explanatory variables. Significant reductions in VO2peak (p 

  • Airway obstruction, dynamic hyperinflation, and breathing pattern during incremental exercise in COPD patients
    Physiological Reports, 2014
    Co-Authors: Bente Frisk, Jon A. Hardie, Birgitte Espehaug, Liv I. Strand, Rolf Moe-nilssen, Tomas M. L. Eagan, Per Bakke, Einar Thorsen
    Abstract:

    Ventilatory capacity is reduced in chronic obstructive pulmonary disease (COPD) patients. Tidal Volume (VT) is lower and breathing frequency higher at a given ventilation (VE) compared to healthy subjects. We examined whether airflow limitation and dynamic hyperinflation in COPD patients were related to breathing pattern. An incremental treadmill exercise test was performed in 63 COPD patients (35 men), aged 65 years (48–79 years) with a mean forced expiratory Volume in 1 sec (FEV1) of 48% of predicted (SD = 15%). Data were averaged over 20‐sec intervals. The relationship between VE and VT was described by the quadratic equation VT = a + bVE + cVE2 for each subject. The relationships between the curve parameters b and c, and spirometric variables and dynamic hyperinflation measured as the difference in Inspiratory capacity from start to end of exercise, were analyzed by multivariate linear regression. The relationship between VE and VT could be described by a quadratic model in 59 patients with median R2 of 0.90 (0.40–0.98). The linear coefficient (b) was negatively (P = 0.001) and the quadratic coefficient (c) positively (P < 0.001) related to FEV1. Forced vital capacity, gender, height, weight, age, Inspiratory Reserve Volume, and dynamic hyperinflation were not associated with the curve parameters after adjusting for FEV1. We concluded that a quadratic model could satisfactorily describe the relationship between VE and VT in most COPD patients. The curve parameters were related to FEV1. With a lower FEV1, maximal VT was lower and achieved at a lower VE. Dynamic hyperinflation was not related to breathing pattern when adjusting for FEV1.

Dirceu Costa - One of the best experts on this subject based on the ideXlab platform.

  • Can a physical activity similar to activities of daily living cause dynamic hyperinflation and change the thoracoabdominal configuration in patients with chronic obstructive pulmonary disease
    International Journal of Chronic Obstructive Pulmonary Disease, 2019
    Co-Authors: Aldenice Magalhães Capeletti, Adriana Do Carmo Santos Sousa, Carla Lima Feitoza, Renata P. Basso-vanelli, Évelim L. F. D. Gomes, Dirceu Costa
    Abstract:

    : Introduction: COPD is characterized by the ventilatory limitation, with reduction of the Inspiratory Reserve Volume and dynamic hyperinflation (DH), which changes the configuration of the thoracic compartment, resulting in a disadvantage in respiratory muscle kinetics, and reduced functional capacity. The optoelectronic plethysmography (OEP) has been used to monitor changes in thoracoabdominal mobility. The Glittre-ADL test is a short battery of functional tests that simulate activities of daily living. In mild and moderate COPD, the effect of Glittre-ADL on thoracoabdominal kinetics and DH is understudied. Objective: The aim of our study was to evaluate the acute effects of the Glittre-ADL test on lung function and thoracoabdominal mobility using OEP in patients with mild and moderate COPD. Materials and methods: Twenty-five male and female patients between 45 and 80 years of age with COPD were submitted to the exercises that simulated Glittre-ADL test. Spirometry and OEP were performed before and after the test. Results: After the Glittre test, increases were found in EV (p=0.005), percentage of contribution of the abdominal compartment (p=0.054) and expiratory Reserve Volume (ERV) (p=0.006) and reductions were found in the contribution of the upper thoracic compartment (p=0.008) and Inspiratory capacity (IC) (p=0.040). Conclusion: The acute effect of ADL was a change in thoracoabdominal kinetics, especially the percentage of contribution of the abdominal compartment, as demonstrated by OEP. These findings, together with the reduction in IC and increase in ERV, after the Glittre-ADL test suggest the occurrence of DH, even in patients with mild to moderate COPD according to the GOLD classification.

  • Pulmonary Function after Weight Loss in Obese Women Undergoing Roux-en-Y Gastric Bypass: One-Year Followup
    International Scholarly Research Notices, 2013
    Co-Authors: Marcela Barbalho-moulim, Gustavo Peixoto Soares Miguel, Eli Maria Pazzianotto Forti, Flávio Do Amaral Campos, Fabiana Sobral Peixoto-souza, Dirceu Costa
    Abstract:

    Introduction. Obesity is a condition that causes damage to the respiratory function. However, studies have demonstrated that weight loss due to bariatric surgery has resulted in a huge improvement on some lung Volumes, but controversy still persists regarding the behavior of the respiratory muscle strength and IRV (Inspiratory Reserve Volume). Objective. To evaluate the effect of weight loss, after 1 year of the Roux-en-Y gastric bypass surgery (RYGB), on the lung Volumes and the respiratory muscle strength in obese women. Methods. 24 obese women candidates were recruited for RYGB. Lung Volumes (spirometry) and respiratory muscle strength were evaluated in preoperative period and one year after surgery. Results. There was a significant increase in some lung Volumes. However, when examining the components of the VC (vital capacity) separately, an increase in ERV (expiratory Reserve Volume) and reduction of IRV were observed. Moreover, a statistically significant reduction in the values of respiratory muscle strength was recorded: MIP (maximal Inspiratory pressure) and MEP (maximal expiratory pressure). Conclusion. Weight loss induced by bariatric surgery provides an increase in some lung Volumes of obese women, but reduction in IRV. Additionally, there was also a reduction in the respiratory muscle strength.

  • The impact of obesity on pulmonary function in adult women
    Clinics, 2008
    Co-Authors: Dirceu Costa, Marcela Cangussu Barbalho, Gustavo Peixoto Soares Miguel, Eli Maria Pazzianotto Forti, João Luiz Moreira Coutinho Azevedo
    Abstract:

    INTRODUCTION: Obesity can cause deleterious effects on respiratory function and impair health and quality of life. OBJECTIVE: To evaluate the effects of obesity on the pulmonary function of adult women. METHODS: An obese group, constituted of 20 women between 20 and 35 years old with a BMI of 35 - 49.99 kg/m2 who were non-smokers and sedentary and had no lung disease were recruited. The non-obese group consisted of 20 women between 20 and 35 years old who were sedentary and non-smokers and had no lung disease and a body mass index between 18.5 and 24.99 kg/m2. Spirometry was performed in all subjects. The statistical analysis consisted of parametric or non-parametric tests, depending on the distribution of each variable, considering p < 0.05 to be statistically significant. RESULTS: The obese group presented a mean age of 25.85 ± 3.89 years and a mean BMI of 41.1 ± 3.46 kg/m2, and the non-obese group presented a mean age of 23.9 ± 2.97 years and a mean body mass index of 21.91 ± 1.81 kg/m2. There were no significant differences between the obese group and the non-obese group as to the age, vital capacity, tidal Volume, forced vital capacity, and forced expiratory Volume in one second. However, the obese group presented a greater Inspiratory Reserve Volume (2.44 ± 0.47 L vs. 1.87 ± 0.42 L), a lower expiratory Reserve Volume (0.52 ± 0.32 L vs. 1.15 ± 0.32 L), and a maximal voluntary ventilation (108.5 ± 13.3 L/min vs. 122.6 ± 19.8 L/min) than the non-obese group, respectively. CONCLUSION: The alterations evidenced in the components of the vital capacity (Inspiratory Reserve Volume and expiratory Reserve Volume) suggest damage to the chest mechanics caused by obesity. These factors probably contributed to a reduction of the maximal voluntary ventilation.

Bente Frisk - One of the best experts on this subject based on the ideXlab platform.

  • Peak oxygen uptake and breathing pattern in COPD patients – a four-year longitudinal study
    BMC Pulmonary Medicine, 2015
    Co-Authors: Bente Frisk, Jon A. Hardie, Birgitte Espehaug, Liv I. Strand, Rolf Moe-nilssen, Tomas M. L. Eagan, Per S. Bakke, Einar Thorsen
    Abstract:

    Background Activities of daily living in patients with chronic obstructive pulmonary disease (COPD) are limited by exertional dyspnea and reduced exercise capacity. The aims of the study were to examine longitudinal changes in peak oxygen uptake (V̇O_2peak), peak minute ventilation (V̇_Epeak) and breathing pattern over four years in a group of COPD patients, and to examine potential explanatory variables of change. Methods This longitudinal study included 63 COPD patients, aged 44-75 years, with a mean forced expiratory Volume in one second (FEV_1) at baseline of 51 % of predicted (SD = 14). The patients performed two cardiopulmonary exercise tests (CPETs) on treadmill 4.5 years apart. The relationship between changes in V̇O_2peak and V̇_Epeak and possible explanatory variables, including dynamic lung Volumes and Inspiratory capacity (IC), were analysed by multivariate linear regression analysis. The breathing pattern in terms of the relationship between minute ventilation (V̇_E) and tidal Volume (V_T) was described by a quadratic equation, V_T = a + b∙V̇_E + c∙V̇_E^2, for each test. The V_Tmax was calculated from the individual quadratic relationships, and was the point where the first derivative of the quadratic equation was zero. The mean changes in the curve parameters (CPET2 minus CPET1) and V_Tmax were analysed by bivariate and multivariate linear regression analyses with age, sex, height, changes in weight, lung function, IC and Inspiratory Reserve Volume as possible explanatory variables. Results Significant reductions in V̇O_2peak ( p  

  • Peak oxygen uptake and breathing pattern in COPD patients – A four year longitudinal study
    BMC Pulmonary Medicine, 2015
    Co-Authors: Bente Frisk, Jon A. Hardie, Birgitte Espehaug, Liv I. Strand, Rolf Moe-nilssen, Tomas M. L. Eagan, Per Bakke, Einar Thorsen
    Abstract:

    Activities of daily living in patients with chronic obstructive pulmonary disease (COPD) are limited by exertional dyspnea and reduced exercise capacity. The aims of the study were to examine longitudinal changes in peak oxygen uptake (VO2peak), peak minute ventilation (VEpeak) and breathing pattern over four years in a group of COPD patients, and to examine potential explanatory variables of change. This longitudinal study included 63 COPD patients, aged 44-75 years, with a mean forced expiratory Volume in one second (FEV1) at baseline of 51 % of predicted (SD = 14). The patients performed two cardiopulmonary exercise tests (CPETs) on treadmill 4.5 years apart. The relationship between changes in VO2peak and VEpeak and possible explanatory variables, including dynamic lung Volumes and Inspiratory capacity (IC), were analysed by multivariate linear regression analysis. The breathing pattern in terms of the relationship between minute ventilation (VE) and tidal Volume (VT) was described by a quadratic equation, VT = a + b∙VE + c∙VE2, for each test. The VTmax was calculated from the individual quadratic relationships, and was the point where the first derivative of the quadratic equation was zero. The mean changes in the curve parameters (CPET2 minus CPET1) and VTmax were analysed by bivariate and multivariate linear regression analyses with age, sex, height, changes in weight, lung function, IC and Inspiratory Reserve Volume as possible explanatory variables. Significant reductions in VO2peak (p 

  • Airway obstruction, dynamic hyperinflation, and breathing pattern during incremental exercise in COPD patients
    Physiological Reports, 2014
    Co-Authors: Bente Frisk, Jon A. Hardie, Birgitte Espehaug, Liv I. Strand, Rolf Moe-nilssen, Tomas M. L. Eagan, Per Bakke, Einar Thorsen
    Abstract:

    Ventilatory capacity is reduced in chronic obstructive pulmonary disease (COPD) patients. Tidal Volume (VT) is lower and breathing frequency higher at a given ventilation (VE) compared to healthy subjects. We examined whether airflow limitation and dynamic hyperinflation in COPD patients were related to breathing pattern. An incremental treadmill exercise test was performed in 63 COPD patients (35 men), aged 65 years (48–79 years) with a mean forced expiratory Volume in 1 sec (FEV1) of 48% of predicted (SD = 15%). Data were averaged over 20‐sec intervals. The relationship between VE and VT was described by the quadratic equation VT = a + bVE + cVE2 for each subject. The relationships between the curve parameters b and c, and spirometric variables and dynamic hyperinflation measured as the difference in Inspiratory capacity from start to end of exercise, were analyzed by multivariate linear regression. The relationship between VE and VT could be described by a quadratic model in 59 patients with median R2 of 0.90 (0.40–0.98). The linear coefficient (b) was negatively (P = 0.001) and the quadratic coefficient (c) positively (P < 0.001) related to FEV1. Forced vital capacity, gender, height, weight, age, Inspiratory Reserve Volume, and dynamic hyperinflation were not associated with the curve parameters after adjusting for FEV1. We concluded that a quadratic model could satisfactorily describe the relationship between VE and VT in most COPD patients. The curve parameters were related to FEV1. With a lower FEV1, maximal VT was lower and achieved at a lower VE. Dynamic hyperinflation was not related to breathing pattern when adjusting for FEV1.

Endang Kumaidah - One of the best experts on this subject based on the ideXlab platform.

  • perbedaan nilai tidal Volume Inspiratory Reserve Volume dan Inspiratory capacity antar cabang olahraga pada atlet usia 6 12 tahun studi pada cabang olahraga bola voli sepak bola renang dantaekwondo di kota semarang
    2015
    Co-Authors: Isfahan Dwi Putra, Yuswo Supadmo, Endang Kumaidah
    Abstract:

    Background: The peak of human body growth and development happens during childhood with different intensity of activities and exercise. It influences the level of physical fitness and health. This research states that daily exercise has a significant impact towards the function of cardiorespiratory system. Each kind of sport has different energy system depends on the kind and the intensity of exercise. Aim: To prove the difference tidal Volume, Inspiratory Reserve Volume and Inspiratory capacity on athlete in age 6-12 between swimmer, taekwondo player, football player and volleyball player in Semarang. Method: This cross-sectional study was done in 20 male athlete age 6-12 each sport branches, being in total 80 athlete. Among respiratory functions test, TV,IRV and IC ware measured using Spirometer spirolab II. Kruskal-Wallis test and One-way annova was applied for statistical analysis. Result: Mean TV values volleyball athlete is 1,12 L, football athlete 1,06 L, swimming athlete 1,27 L and taekwondo athlete 0,89 L. Mean IRV values volleyball athlete is 0,54 L, football athlete 0,70 L, swimming athlete 0,71 L and taekwondo athlete 0,67 L. Mean IC values volleyball athlete is 1,66 L, football athlete 1,76 L, swimming athlete 1,91 L and taekwondo athlete 1,56 L. Swimmer athlete has higher VC, IRV and IC values than other athlete. Conclusion: There is a significant difference TV values between sport branches in athlete age 6-12. Beside that, there is not a significant difference IRV and IC values between sport branches in athlete age 6-12. Keyword: Athlete, tidal Volume, Inspiratory Reserve Volume, Inspiratory capacity, TV, IRV, IC.

  • perbedaan nilai tidal Volume Inspiratory Reserve Volume dan Inspiratory capacity antar cabang olahraga pada atlet usia 6 12 tahun
    JURNAL KEDOKTERAN DIPONEGORO, 2015
    Co-Authors: Isfahan Dwi Putra, Yuswo Supatmo, Endang Kumaidah
    Abstract:

    Background: The peak of human body growth and development happens during childhood with different intensity of activities and exercise. It influences the level of physical fitness and health. This research states that daily exercise has a significant impact towards the function of cardiorespiratory system. Each kind of sport has different energy system depends on the kind and the intensity of exercise. Aim: To prove the difference tidal Volume, Inspiratory Reserve Volume and Inspiratory capacity on athlete in age 6-12 between swimmer, taekwondo player, football player and volleyball player in Semarang. Method: This cross-sectional study was done in 20 male athlete age 6-12 each sport branches, being in total 80 athlete. Among respiratory functions test, TV,IRV and IC ware measured using Spirometer spirolab II. Kruskal-Wallis test and One-way annova was applied for statistical analysis. Result: Mean TV values volleyball athlete is 1,12 L, football athlete 1,06 L, swimming athlete 1,27 L and taekwondo athlete 0,89 L. Mean IRV values volleyball athlete is 0,54 L, football athlete 0,70 L, swimming athlete 0,71 L and taekwondo athlete 0,67 L. Mean IC values volleyball athlete is 1,66 L, football athlete 1,76 L, swimming athlete 1,91 L and taekwondo athlete 1,56 L. Swimmer athlete has higher VC, IRV and IC values than other athlete. Conclusion: There is a significant difference TV values between sport branches in athlete age 6-12. Beside that, there is not a significant difference IRV and IC values between sport branches in athlete age 6-12.

Marcela Barbalho-moulim - One of the best experts on this subject based on the ideXlab platform.

  • Pulmonary Function after Weight Loss in Obese Women Undergoing Roux-en-Y Gastric Bypass: One-Year Followup
    International Scholarly Research Notices, 2013
    Co-Authors: Marcela Barbalho-moulim, Gustavo Peixoto Soares Miguel, Eli Maria Pazzianotto Forti, Flávio Do Amaral Campos, Fabiana Sobral Peixoto-souza, Dirceu Costa
    Abstract:

    Introduction. Obesity is a condition that causes damage to the respiratory function. However, studies have demonstrated that weight loss due to bariatric surgery has resulted in a huge improvement on some lung Volumes, but controversy still persists regarding the behavior of the respiratory muscle strength and IRV (Inspiratory Reserve Volume). Objective. To evaluate the effect of weight loss, after 1 year of the Roux-en-Y gastric bypass surgery (RYGB), on the lung Volumes and the respiratory muscle strength in obese women. Methods. 24 obese women candidates were recruited for RYGB. Lung Volumes (spirometry) and respiratory muscle strength were evaluated in preoperative period and one year after surgery. Results. There was a significant increase in some lung Volumes. However, when examining the components of the VC (vital capacity) separately, an increase in ERV (expiratory Reserve Volume) and reduction of IRV were observed. Moreover, a statistically significant reduction in the values of respiratory muscle strength was recorded: MIP (maximal Inspiratory pressure) and MEP (maximal expiratory pressure). Conclusion. Weight loss induced by bariatric surgery provides an increase in some lung Volumes of obese women, but reduction in IRV. Additionally, there was also a reduction in the respiratory muscle strength.

  • Study on pulmonary Volumes and thoracoabdominal mobility in morbidly obese women undergoing bariatric surgery, treated with two different physical therapy methods
    Revista Brasileira De Fisioterapia, 2009
    Co-Authors: Daniel P. Costa, Emp Forti, Marcela Barbalho-moulim, Irineu Rasera-junior
    Abstract:

    OBJECTIVE: To compare the effects of conventional respiratory physical therapy (CRP) and CRP associated with transcutaneous electrical diaphragmatic stimulation (TEDS) on the pulmonary Volumes and the thoracoabdominal mobility of patients undergoing bariatric surgery. METHODS: This randomized prospective study evaluated 44 female candidates for bariatric surgery (age 37.4±8.1 years; body mass index 47.4±6.1 kg/m2), before surgery and 15 and 30 days after surgery. The candidates were evaluated with regard to measurements of Inspiratory Reserve Volume (IRV), expiratory Reserve Volume (ERV), Inspiratory capacity (IC) and thoracoabdominal mobility, by means of spirometry and cirtometry, respectively. CRP consisted of diaphragmatic respiratory exercises, deep fractionated inspiration and respiratory exercises associated with upper limb movement. One set of 10 repetitions of each exercise was carried out twice daily while hospitalized. For TEDS, two electrodes were placed on the parasternal region, next to the xiphoid process, and another two between the sixth and seventh intercostal spaces, bilaterally on the anterior axillary lines. Friedman's test was used to compare repeated measures within groups, and the Mann-Whitney test for comparisons between groups. P values