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Jesse M Pines - One of the best experts on this subject based on the ideXlab platform.
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the epidemiology of Intentional non fatal self harm Poisoning in the united states 2001 2004
Journal of Medical Toxicology, 2007Co-Authors: Jane Prosser, Jeanmarie Perrone, Jesse M PinesAbstract:Introduction Suicide attempts through Intentional Poisoning are an important public health concern. This investigation sought to determine the different US incident rates of Poisonings (with intent to do self-harm) by race, sex, and gender.
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The epidemiology of Intentional non-fatal self-harm Poisoning in the United States: 2001–2004
Journal of Medical Toxicology, 2007Co-Authors: Jane Prosser, Jeanmarie Perrone, Jesse M PinesAbstract:Introduction Suicide attempts through Intentional Poisoning are an important public health concern. This investigation sought to determine the different US incident rates of Poisonings (with intent to do self-harm) by race, sex, and gender. Methods We used data from the National Electronic Injury Surveillance System — All Injury Program (NEISS-AIP) to describe differences in incidence rates of non-fatal, self-harm Poisonings evaluated in US emergency departments (ED) from 2001 to 2004. WISQARS defines self-harm as “either confirmed or suspected from injury or Poisoning resulting from a deliberate act inflicted on oneself with the intent to take one’s own life or harm oneself.” Results From 2001 to 2004, there were 976,974 (95% Confidence Interval (CI) 772,884 – 1,181,065) non-fatal self-harm Poisonings reported in US Emergency Departments. Young white females between 15 to 19 years of age were at highest risk with an incidence rate of 248 per 100,000 (95% CI 180 – 315). Females had higher rates of self-harm Poisonings than males: the rate for females was 101 per 100,000 (95% CI 81 – 123); the rate for males was 66 per 100,000 (95% CI 51 – 81), p < 0.001. Whites had slightly higher rates than blacks, and significantly higher rates than Hispanics: whites rates were 71 per 100,000 (95% 51 – 91); black rates were 65 per 100,000 (95% CI 35 – 96), and Hispanic rates were 23 per 100,000 (95% 10 – 37). There was a significant increase in the incidence rate from 2002 to 2003 (p < 0.001). Incident rates decreased for females and males older than 19 years of age (p < 0.001 for males and females). Conclusion Recently, the incidence of self-harm Poisoning has risen considerably. It rose from 75 (CI 53–98) per 100,000 in 2002 to 94 (CI 74–115) per 100,000 in 2003; incidence remained relatively steady in 2004. Whites have higher incidence rates than blacks and significantly higher incidence rates than Hispanics. Females are at higher risk than males, and adolescent white females are at highest risk. An understanding of the demographic factors associated with self-harm Poisoning may provide useful information to improve prevention and treatment strategies.
Keith W Dockery - One of the best experts on this subject based on the ideXlab platform.
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fatal Intentional salt Poisoning associated with a radiopaque mass
Pediatrics, 1992Co-Authors: Keith W DockeryAbstract:Intentional Poisoning has become recognized more widely as a form of child abuse in recent years.1 Many substances have been reported as the agents used, including common table salt (sodium chloride).2-5 However, there is very little published information on the manifestations of salt Poisoning when it is administered in large quantities in the undissolved, crystallized form. A case of fatal salt Poisoning is reported which emphasizes two characteristics of crystallized salt that have not been described previously and which emphasizes once again that Poisoning in young children may be a form of child abuse. Case Report A 5-year-old girl was brought to a local emergency department with seizures and hypernatremia.
Jeffrey Brent - One of the best experts on this subject based on the ideXlab platform.
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Current Management of Ethylene Glycol Poisoning
Drugs, 2001Co-Authors: Jeffrey BrentAbstract:Ethylene glycol, a common antifreeze, coolant and industrial solvent, is responsible for many instances of accidental and Intentional Poisoning annually. Following ingestion, ethylene glycol is first hepatically metabolised to glycoaldehyde by alcohol dehydrogenase. Glycoaldehyde is then oxidised to glycolic acid, glyoxylic acid and finally oxalic acid. While ethylene glycol itself causes intoxication, the accumulation of toxic metabolites is responsible for the potentially fatal acidosis and renal failure, which characterises ethylene glycol Poisoning. Treatment of ethylene glycol Poisoning consists of emergent stabilisation, correction of metabolic acidosis, inhibition of further metabolism and enhancing elimination of both unmetabolised parent compound and its metabolites. The prevention of ethylene glycol metabolism is accomplished by the use of antidotes that inhibit alcohol dehydrogenase. Historically, this has been done with intoxicating doses of ethanol. At a sufficiently high concentration, ethanol saturates alcohol dehydrogenase, preventing it from acting on ethylene glycol, thus allowing the latter to be excreted unchanged by the kidneys. However, ethanol therapy is complicated by its own inherent toxicity, and the need to carefully monitor serum ethanol concentrations and adjust the rate of administration. A recent alternative to ethanol therapy is fomepizole, or 4-methylpyrazole. Like ethanol, fomepizole inhibits alcohol dehydrogenase; however it does so without producing serious adverse effects. Unlike ethanol, fomepizole is metabolised in a predictable manner, allowing for the use of a standard, validated administration regimen. Fomepizole therapy eliminates the need for the haemodialysis that is required in selected patients who are non-acidotic and have adequate renal function.
Jane Prosser - One of the best experts on this subject based on the ideXlab platform.
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the epidemiology of Intentional non fatal self harm Poisoning in the united states 2001 2004
Journal of Medical Toxicology, 2007Co-Authors: Jane Prosser, Jeanmarie Perrone, Jesse M PinesAbstract:Introduction Suicide attempts through Intentional Poisoning are an important public health concern. This investigation sought to determine the different US incident rates of Poisonings (with intent to do self-harm) by race, sex, and gender.
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The epidemiology of Intentional non-fatal self-harm Poisoning in the United States: 2001–2004
Journal of Medical Toxicology, 2007Co-Authors: Jane Prosser, Jeanmarie Perrone, Jesse M PinesAbstract:Introduction Suicide attempts through Intentional Poisoning are an important public health concern. This investigation sought to determine the different US incident rates of Poisonings (with intent to do self-harm) by race, sex, and gender. Methods We used data from the National Electronic Injury Surveillance System — All Injury Program (NEISS-AIP) to describe differences in incidence rates of non-fatal, self-harm Poisonings evaluated in US emergency departments (ED) from 2001 to 2004. WISQARS defines self-harm as “either confirmed or suspected from injury or Poisoning resulting from a deliberate act inflicted on oneself with the intent to take one’s own life or harm oneself.” Results From 2001 to 2004, there were 976,974 (95% Confidence Interval (CI) 772,884 – 1,181,065) non-fatal self-harm Poisonings reported in US Emergency Departments. Young white females between 15 to 19 years of age were at highest risk with an incidence rate of 248 per 100,000 (95% CI 180 – 315). Females had higher rates of self-harm Poisonings than males: the rate for females was 101 per 100,000 (95% CI 81 – 123); the rate for males was 66 per 100,000 (95% CI 51 – 81), p < 0.001. Whites had slightly higher rates than blacks, and significantly higher rates than Hispanics: whites rates were 71 per 100,000 (95% 51 – 91); black rates were 65 per 100,000 (95% CI 35 – 96), and Hispanic rates were 23 per 100,000 (95% 10 – 37). There was a significant increase in the incidence rate from 2002 to 2003 (p < 0.001). Incident rates decreased for females and males older than 19 years of age (p < 0.001 for males and females). Conclusion Recently, the incidence of self-harm Poisoning has risen considerably. It rose from 75 (CI 53–98) per 100,000 in 2002 to 94 (CI 74–115) per 100,000 in 2003; incidence remained relatively steady in 2004. Whites have higher incidence rates than blacks and significantly higher incidence rates than Hispanics. Females are at higher risk than males, and adolescent white females are at highest risk. An understanding of the demographic factors associated with self-harm Poisoning may provide useful information to improve prevention and treatment strategies.
Wesam Abuznadah - One of the best experts on this subject based on the ideXlab platform.
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Pattern of Drug Overdose and Chemical Poisoning Among Patients Attending an Emergency Department, Western Saudi Arabia
Journal of Community Health, 2015Co-Authors: Mohamad Bakhaidar, Saber Jan, Ahmad Attar, Basim Alsaywid, Fayssal Farahat, Wesam AbuznadahAbstract:Poisoning is a medical emergency that represent a major health problem all over the world. Studies on drug overdose and chemical Poisoning are very limited in Saudi Arabia (SA). We aimed to describe the current pattern and assess risk factors of drug overdose and chemical Poisoning in King Khalid National Guard hospital, Jeddah, SA. Medical records of patients attended emergency department in King Khalid National Guard hospital during the period from January 2008 to December 2012 due to drug overdose and chemical Poisoning were reviewed. A total of 129 cases were included in the study. The majority of the population was Saudi (97.7 %), and almost half of them were females (54.3 %). Children under 12 years were the most affected age group (44.2 %). Drug overdose was the most common cause of Poisoning (92.2 %). Analgesics and non-steroidal anti-inflammatory drugs represented the highest percentage of used medications (20.4 %). The most commonly reported symptoms were symptoms of the central nervous system (57.4 %) followed by GIT symptoms (41.9 %). Intentional Poisoning was reported in 34 cases (26.4 %). Female patients were significantly more likely to attempt suicide than male patients (OR = 7.22, 95 % CI = 1.70, 30.62). Children continue to be at high risk for medication and chemical Poisoning. Accessibility to medications at homes encountered for most of Poisoning cases among children. Implementing methods to raise public awareness and minimize children access to medications would significantly contribute to reducing burden of this problem on the community.
