The Experts below are selected from a list of 699 Experts worldwide ranked by ideXlab platform
Nelson, Pilar Juliet - One of the best experts on this subject based on the ideXlab platform.
-
Leukocyte recruitment to the peritoneum of cultured summer flounder (Paralichthys dentatus) during bacterial infection
DigitalCommons@URI, 2014Co-Authors: Nelson, Pilar JulietAbstract:Summer flounder (Paralichthys dentatus) constitutes a major fishery in the coastal northeastern United States. Spurred by population declines, cultivation of summer flounder began in 1996, but expansion of culture efforts has been constrained by disease outbreaks. Flounder Infectious Necrotizing Enteritis (FINE) causes significant mortality of juvenile flounder. The disease is characterized by ascites, Intestinal Prolapse, and severe inflammation of the mesentery and posterior Intestinal serosa, often resulting in Intestinal rupture. FINE is caused by Vibrio harveyi, a bacterial pathogen of cultured marine fish and invertebrates. To better understand the immune response to FINE, recruitment and fluctuation of leukocytes within the summer flounder peritoneum were investigated during intraperitoneal challenge with V. harveyi. Consistent with the pathology of FINE, massive infiltration of large granular leukocytes was observed in coelom of flounder 24 hours after intra-peritoneal injection of live bacteria. In these fish, the number of lymphocytes doubled, though the number of B-cells was not significantly different from saline-injected animals. The large influx of granular cells resulted in a 15-fold increase in that population, decreasing the lymphocyte population from ∼65% to ∼20% of the total coelomic leukocyte pool. It is hypothesized that the influx of large granular leukocytes into the coelom of challenged animals may contribute significantly to the pathology of the disease
-
LEUKOCYTE RECRUITMENT TO THE PERITONEUM OF CULTURED SUMMER FLOUNDER (\u3cem\u3ePARALICHTHYS DENTATUS\u3c/em\u3e) DURING BACTERIAL
DigitalCommons@URI, 2014Co-Authors: Nelson, Pilar JulietAbstract:Summer flounder (Paralichthys dentatus) constitutes a major fishery in the coastal northeastern United States. Spurred by population declines, cultivation of summer flounder began in 1996, but expansion of culture efforts has been constrained by disease outbreaks. Flounder Infectious Necrotizing Enteritis (FINE) causes significant mortality of juvenile flounder. The disease is characterized by ascites, Intestinal Prolapse, and severe inflammation of the mesentery and posterior Intestinal serosa, often resulting in Intestinal rupture. FINE is caused by Vibrio harveyi, a bacterial pathogen of cultured marine fish and invertebrates. To better understand the immune response to FINE, recruitment and fluctuation of leukocytes within the summer flounder peritoneum were investigated during intraperitoneal challenge with V. harveyi. Consistent with the pathology of FINE, massive infiltration of large granular leukocytes was observed in coelom of flounder 24 hours after intra-peritoneal injection of live bacteria. In these fish, the number of lymphocytes doubled, though the number of B-cells was not significantly different from saline-injected animals. The large influx of granular cells resulted in a 15-fold increase in that population, decreasing the lymphocyte population from ~65% to ~20% of the total coelomic leukocyte pool. It is hypothesized that the influx of large granular leukocytes into the coelom of challenged animals may contribute significantly to the pathology of the disease
Murat Gultekin - One of the best experts on this subject based on the ideXlab platform.
-
posthysterectomy Intestinal Prolapse after coitus and vaginal repair
Archives of Gynecology and Obstetrics, 2005Co-Authors: K Yuce, Polat Dursun, Murat GultekinAbstract:Introduction Transvaginal bowel evisceration following either vaginal or abdominal gynecologic operations is a very rare complication. Furthermore, vaginal cuff rupture with the Prolapse of the small bowel through the vagina during sexual intercourse after abdominal hysterectomy in a premenopausal woman is even more rare. However, regardless of the etiology, transvaginal evisceration requires prompt recognition and surgical intervention.
John P Gearhart - One of the best experts on this subject based on the ideXlab platform.
-
anterior innominate osteotomy in repair of bladder exstrophy
Journal of Bone and Joint Surgery American Volume, 2001Co-Authors: Paul D Sponseller, Mihir M Jani, Robert D Jeffs, John P GearhartAbstract:Background: Classic bladder exstrophy is a developmental defect presenting at birth with a wide pubic separation and an exposed bladder; cloacal exstrophy involves, in addition, Intestinal Prolapse. Reconstruction requires several surgical procedures. The use of anterior iliac osteotomies in this process has not been reviewed in a large series. Methods: We reviewed the results of eighty-six anterior innominate osteotomies performed in conjunction with genitourinary repair of classic and cloacal bladder exstrophy in eighty-two patients. Clinical outcome measures were successful bladder closure, achievement of continence, and maintenance of a normal gait. Radiographs of the pelvis were reviewed, and the pubic intersymphyseal diastasis (a measure of the reduction in tension on the anterior closure) was measured preoperatively and at three time-points postoperatively. Children with classic exstrophy who had undergone osteotomy and bladder neck reconstruction but not bladder augmentation were divided into four groups on the basis of the degree of continence. In addition, children with classic exstrophy were stratified according to age at the time of the osteotomy. The mean postoperative percent reduction in the amount of the original diastasis was determined for all groups. Results: Children with classic exstrophy and those with cloacal exstrophy had correction of the diastasis after the osteotomy, with greater correction in those with classic exstrophy, presumably because of better bone quality. Daytime continence was achieved with anterior osteotomy and bladder neck reconstruction in 74% of the children for whom continence was a goal. However, no difference in the symphyseal diastasis or in the percentage of pubic reduction was detected among the four continence groups. Children who were older at the time of the osteotomy maintained better correction over time. Wound dehiscence or bladder Prolapse occurred in 4% of the patients who had osteotomy and primary closure, and the only important complication of the osteotomies was transient palsy of the left femoral nerve in seven children. Conclusions: Anterior innominate osteotomy is an effective part of reconstructive repair of bladder exstrophy. The primary goals of the osteotomy are to reduce the tension in the closed bladder and the lower abdominal wall and to promote continence by restoring the sling of the pelvic floor muscles. These goals can be achieved in the majority of patients.
K Yuce - One of the best experts on this subject based on the ideXlab platform.
-
posthysterectomy Intestinal Prolapse after coitus and vaginal repair
Archives of Gynecology and Obstetrics, 2005Co-Authors: K Yuce, Polat Dursun, Murat GultekinAbstract:Introduction Transvaginal bowel evisceration following either vaginal or abdominal gynecologic operations is a very rare complication. Furthermore, vaginal cuff rupture with the Prolapse of the small bowel through the vagina during sexual intercourse after abdominal hysterectomy in a premenopausal woman is even more rare. However, regardless of the etiology, transvaginal evisceration requires prompt recognition and surgical intervention.
Paul D Sponseller - One of the best experts on this subject based on the ideXlab platform.
-
anterior innominate osteotomy in repair of bladder exstrophy
Journal of Bone and Joint Surgery American Volume, 2001Co-Authors: Paul D Sponseller, Mihir M Jani, Robert D Jeffs, John P GearhartAbstract:Background: Classic bladder exstrophy is a developmental defect presenting at birth with a wide pubic separation and an exposed bladder; cloacal exstrophy involves, in addition, Intestinal Prolapse. Reconstruction requires several surgical procedures. The use of anterior iliac osteotomies in this process has not been reviewed in a large series. Methods: We reviewed the results of eighty-six anterior innominate osteotomies performed in conjunction with genitourinary repair of classic and cloacal bladder exstrophy in eighty-two patients. Clinical outcome measures were successful bladder closure, achievement of continence, and maintenance of a normal gait. Radiographs of the pelvis were reviewed, and the pubic intersymphyseal diastasis (a measure of the reduction in tension on the anterior closure) was measured preoperatively and at three time-points postoperatively. Children with classic exstrophy who had undergone osteotomy and bladder neck reconstruction but not bladder augmentation were divided into four groups on the basis of the degree of continence. In addition, children with classic exstrophy were stratified according to age at the time of the osteotomy. The mean postoperative percent reduction in the amount of the original diastasis was determined for all groups. Results: Children with classic exstrophy and those with cloacal exstrophy had correction of the diastasis after the osteotomy, with greater correction in those with classic exstrophy, presumably because of better bone quality. Daytime continence was achieved with anterior osteotomy and bladder neck reconstruction in 74% of the children for whom continence was a goal. However, no difference in the symphyseal diastasis or in the percentage of pubic reduction was detected among the four continence groups. Children who were older at the time of the osteotomy maintained better correction over time. Wound dehiscence or bladder Prolapse occurred in 4% of the patients who had osteotomy and primary closure, and the only important complication of the osteotomies was transient palsy of the left femoral nerve in seven children. Conclusions: Anterior innominate osteotomy is an effective part of reconstructive repair of bladder exstrophy. The primary goals of the osteotomy are to reduce the tension in the closed bladder and the lower abdominal wall and to promote continence by restoring the sling of the pelvic floor muscles. These goals can be achieved in the majority of patients.
