The Experts below are selected from a list of 174 Experts worldwide ranked by ideXlab platform

D E Woodrum - One of the best experts on this subject based on the ideXlab platform.

  • estimation of Intrapleural Pressure in the newborn
    Pediatric Pulmonology, 1990
    Co-Authors: Dennis E Mayock, Jon F Watchko, T A Standaert, D E Woodrum
    Abstract:

    We examined the changes in esophageal (Pes), proximal airway (Paw), and direct Intrapleural (Ppl) Pressure measurements following end-expiratory airway occlusion in anesthetized spontaneously breathing newborn piglets. Simultaneous occluded Pressure measurements were obtained during resting ventilation, inspiratory resistive loaded (IRL) breathing, and bilateral transvenous phrenic nerve stimulation. During spontaneous resting ventilation, occluded Paw/Ppl averaged 104 ± 4% and occluded Pes/Ppl averaged 89 ± 3%. Similar values were found for occluded spontaneous breaths with IRL. During phrenic nerve stimulation at end-expiratory lung volume, occluded Paw/Ppl averaged 104 ± 6% while occluded Pes/Ppl decreased to 70 ± 22%. We conclude that proximal airway Pressure more accurately reflects Intrapleural Pressure than esophageal Pressure with occlusion in newborn swine. During phrenic nerve stimulation, esophageal Pressure measures are grossly inaccurate estimates of Intrapleural Pressure with occlusion. Pediatr Pulmonol 1990; 9:30–33.

Rafal Krenke - One of the best experts on this subject based on the ideXlab platform.

  • therapeutic thoracentesis impact on respiratory rate and Intrapleural Pressure amplitude change
    European Respiratory Journal, 2017
    Co-Authors: Elzbieta M Grabczak, Marcin Michnikowski, Tomasz Golczewski, Monika Zielinskakrawczyk, Krzysztof Zielinski, Piotr Korczynski, Anna Stecka, Rafal Krenke
    Abstract:

    Introduction: Although therapeutic thoracentesis is a common procedure, some physiological aspects of pleural fluid removal have not been adequately studied. Aim: To assess the changes in pleural Pressure amplitude (Ppl ampl ) and respiratory rate(RR) during pleural fluid withdrawal. Material and Methods: This was a prospective study in consecutive patients referred for therapeutic thoracentesis. 23 subjects with symptomatic pleural effusion underwent thoracentesis with pleural Pressure (Ppl) measurement. A computer based electronic system was used to register the Ppl curve at baseline and after the withdrawal of consecutive portions of pleural fluid. In all patients the Ppl curves were analyzed in five points at 0,25%,50%,75% and 100% of the total volume of withdrawn pleural fluid. Results: There were 11 patients with right sided pleural effusion, male predominance (14/9), median age 68(range 46-85 years). In 20(87%) patients pleural effusion was related to malignant diseases. The median total volume of withdrawn pleural fluid was 1800(IQR 1500-2400) ml. An increase of Ppl ampl between the first and last measurement point was registered in 22/23 patients(median Ppl ampl 3.4(2.4-5.9) cmH 2 O vs. 10.7(8.1-15.6) cmH 2 O, respectively(p=0.0000)). Three patterns of Ppl ampl changes were identified.Also, significant increase in RR was registered(p=0.0097), however the patterns of RR changes were more diversified. Conclusion: The therapeutic thoracentesis is associated with significant increase of Ppl ampl and respiratory rate. The significance of these changes should be elucidated in further studies. Acknowledgment The study received financial support from the Polish National Science Centre (grant No 2012/05/B/NZ5/01343).

  • development of an electronic manometer for Intrapleural Pressure monitoring
    Respiration, 2011
    Co-Authors: Rafal Krenke, Elzbieta M Grabczak, Marcin Michnikowski, K J Palko, Ryszarda Chazan, Tomasz Golczewski
    Abstract:

    Background: Measurement of Intrapleural Pressure is useful during various pleural procedures. However, a pleural manometer is rarely available. Objectives: The ai

Kim G Prisk - One of the best experts on this subject based on the ideXlab platform.

Dennis E Mayock - One of the best experts on this subject based on the ideXlab platform.

  • estimation of Intrapleural Pressure in the newborn
    Pediatric Pulmonology, 1990
    Co-Authors: Dennis E Mayock, Jon F Watchko, T A Standaert, D E Woodrum
    Abstract:

    We examined the changes in esophageal (Pes), proximal airway (Paw), and direct Intrapleural (Ppl) Pressure measurements following end-expiratory airway occlusion in anesthetized spontaneously breathing newborn piglets. Simultaneous occluded Pressure measurements were obtained during resting ventilation, inspiratory resistive loaded (IRL) breathing, and bilateral transvenous phrenic nerve stimulation. During spontaneous resting ventilation, occluded Paw/Ppl averaged 104 ± 4% and occluded Pes/Ppl averaged 89 ± 3%. Similar values were found for occluded spontaneous breaths with IRL. During phrenic nerve stimulation at end-expiratory lung volume, occluded Paw/Ppl averaged 104 ± 6% while occluded Pes/Ppl decreased to 70 ± 22%. We conclude that proximal airway Pressure more accurately reflects Intrapleural Pressure than esophageal Pressure with occlusion in newborn swine. During phrenic nerve stimulation, esophageal Pressure measures are grossly inaccurate estimates of Intrapleural Pressure with occlusion. Pediatr Pulmonol 1990; 9:30–33.

Elzbieta M Grabczak - One of the best experts on this subject based on the ideXlab platform.

  • therapeutic thoracentesis impact on respiratory rate and Intrapleural Pressure amplitude change
    European Respiratory Journal, 2017
    Co-Authors: Elzbieta M Grabczak, Marcin Michnikowski, Tomasz Golczewski, Monika Zielinskakrawczyk, Krzysztof Zielinski, Piotr Korczynski, Anna Stecka, Rafal Krenke
    Abstract:

    Introduction: Although therapeutic thoracentesis is a common procedure, some physiological aspects of pleural fluid removal have not been adequately studied. Aim: To assess the changes in pleural Pressure amplitude (Ppl ampl ) and respiratory rate(RR) during pleural fluid withdrawal. Material and Methods: This was a prospective study in consecutive patients referred for therapeutic thoracentesis. 23 subjects with symptomatic pleural effusion underwent thoracentesis with pleural Pressure (Ppl) measurement. A computer based electronic system was used to register the Ppl curve at baseline and after the withdrawal of consecutive portions of pleural fluid. In all patients the Ppl curves were analyzed in five points at 0,25%,50%,75% and 100% of the total volume of withdrawn pleural fluid. Results: There were 11 patients with right sided pleural effusion, male predominance (14/9), median age 68(range 46-85 years). In 20(87%) patients pleural effusion was related to malignant diseases. The median total volume of withdrawn pleural fluid was 1800(IQR 1500-2400) ml. An increase of Ppl ampl between the first and last measurement point was registered in 22/23 patients(median Ppl ampl 3.4(2.4-5.9) cmH 2 O vs. 10.7(8.1-15.6) cmH 2 O, respectively(p=0.0000)). Three patterns of Ppl ampl changes were identified.Also, significant increase in RR was registered(p=0.0097), however the patterns of RR changes were more diversified. Conclusion: The therapeutic thoracentesis is associated with significant increase of Ppl ampl and respiratory rate. The significance of these changes should be elucidated in further studies. Acknowledgment The study received financial support from the Polish National Science Centre (grant No 2012/05/B/NZ5/01343).

  • development of an electronic manometer for Intrapleural Pressure monitoring
    Respiration, 2011
    Co-Authors: Rafal Krenke, Elzbieta M Grabczak, Marcin Michnikowski, K J Palko, Ryszarda Chazan, Tomasz Golczewski
    Abstract:

    Background: Measurement of Intrapleural Pressure is useful during various pleural procedures. However, a pleural manometer is rarely available. Objectives: The ai