The Experts below are selected from a list of 1104 Experts worldwide ranked by ideXlab platform
Jeroen J Bax - One of the best experts on this subject based on the ideXlab platform.
-
effect of cardiac resynchronization therapy in patients without left Intraventricular Dyssynchrony
European Heart Journal, 2012Co-Authors: Gabe B Bleeker, Martin J Schalij, Matteo Bertini, Dominique Auger, See Hooi Ewe, Rutger J. Van Bommel, Tomasz Witkowski, Lieselotvan Van Erven, Jeroen J BaxAbstract:Aims To evaluate the effects of cardiac resynchronization therapy (CRT) on long-term survival of patients without baseline left ventricular (LV) mechanical Dyssynchrony. Methods and results A total of 290 heart failure patients (age 67 ± 10 years, 77% males) without significant baseline LV Dyssynchrony (<60 ms as assessed with tissue Doppler imaging) were treated with CRT. Patients were divided according to the median LV Dyssynchrony measured after 48 h of CRT into two groups. All-cause mortality was compared between the subgroups. In addition, the all-cause mortality rates of these subgroups were compared with the all-cause mortality of 290 heart failure patients treated with CRT who showed significant LV Dyssynchrony (≥60 ms) at baseline. In the group of patients without significant LV Dyssynchrony, median LV Dyssynchrony increased from 22 ms (inter-quartile range 16–34 ms) at baseline to 40 ms (24–56 ms) 48 h after CRT. The cumulative mortality rates at 1-, 2-, and 3-year follow-up of patients with LV Dyssynchrony ≥40 ms 48 h after CRT implantation were significantly higher when compared with patients with LV Dyssynchrony <40 ms (10, 17, and 23 vs. 3, 8, and 10%, respectively; log-rank P < 0.001). Finally, the cumulative mortality rates at 1-, 2-, and 3-year follow-up of patients with baseline LV Dyssynchrony were 3, 8, and 11%, respectively (log-rank P = 0.375 vs. patients with LV Dyssynchrony <40 ms). Induction of LV Dyssynchrony after CRT was an independent predictor of mortality (hazard ratio: 1.247; P = 0.009). Conclusion In patients without significant LV Dyssynchrony, the induction of LV Dyssynchrony after CRT may be related to a less favourable long-term outcome.
-
Effect of cardiac resynchronization therapy in patients without left Intraventricular Dyssynchrony
European heart journal, 2012Co-Authors: Dominique Auger, Gabe B Bleeker, Martin J Schalij, Matteo Bertini, See Hooi Ewe, Rutger J. Van Bommel, Tomasz Witkowski, Lieselotvan Van Erven, Jeroen J BaxAbstract:A total of 290 heart failure patients (age 67+ 10 years, 77% males) without significant baseline LV Dyssynchrony (,60 ms as assessed with tissue Doppler imaging) were treated with CRT. Patients were divided according to the median LV Dyssynchrony measured after 48 h of CRT into two groups. All-cause mortality was compared between the subgroups. In addition, the all-cause mortality rates of these subgroups were compared with the all- cause mortality of 290 heart failure patients treated with CRT who showed significant LV Dyssynchrony (≥60 ms) at baseline. In the group of patients without significant LV Dyssynchrony, median LV Dyssynchrony increased from 22 ms (inter-quartile range 16-34 ms) at baseline to 40 ms (24-56 ms) 48 h after CRT. The cumulative mortality rates at 1-, 2-, and 3-year follow-up of patients with LV Dyssynchrony ≥40 ms 48 h after CRT implantation were sig- nificantly higher when compared with patients with LV Dyssynchrony ,40 ms (10, 17, and 23 vs. 3, 8, and 10%, re- spectively; log-rank P , 0.001). Finally, the cumulative mortality rates at 1-, 2-, and 3-year follow-up of patients with baseline LV Dyssynchrony were 3, 8, and 11%, respectively (log-rank P ¼ 0.375 vs. patients with LV Dyssynchrony ,40 ms). Induction of LV Dyssynchrony after CRT was an independent predictor of mortality (hazard ratio: 1.247; P ¼ 0.009). Conclusion In patients without significant LV Dyssynchrony, the induction of LV Dyssynchrony after CRT may be related to a less
-
Triplane Tissue Doppler Imaging to Evaluate Mechanical Dyssynchrony Before and After Cardiac Resynchronization in a Patient with Congenitally Corrected Transposition of the Great Arteries
Journal of cardiovascular electrophysiology, 2006Co-Authors: Nico R. Van De Veire, Eduard R Holman, Martin J Schalij, Nico A. Blom, Jeroen J BaxAbstract:We report the case of a 13-year-old girl with congenitally corrected transposition of the great arteries. Since the implantation of a conventional pacemaker for acquired complete atrioventricular block, the patient experienced increased heart failure symptoms. Using triplane tissue Doppler imaging, significant Intraventricular Dyssynchrony induced by unilateral pacing and associated with diminished exercise capacity was demonstrated. A biventricular pacemaker was successfully implanted transvenously, leading to synchronous activation of the systemic ventricle and improved exercise capacity.
-
assessment of left ventricular Dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy head to head comparison between tissue doppler imaging and velocity encoded magnetic resonance imaging
Journal of the American College of Cardiology, 2006Co-Authors: Jos J M Westenberg, Eduard R Holman, Johannes H. C. Reiber, Hildo J Lamb, Albert De Roos, Gabe B Bleeker, Martin J Schalij, Rob J Van Der Geest, Ernst E Van Der Wall, Jeroen J BaxAbstract:Objectives This study sought to compare tissue Doppler imaging (TDI) with velocity-encoded (VE) magnetic resonance imaging (MRI) for left ventricular (LV) Dyssynchrony assessment. Background Cardiac resynchronization therapy (CRT) is proposed for patients with heart failure, depressed LV function, and a wide QRS complex. Selection is based mainly on electrocardiogram criteria, but recent data suggest that Intraventricular Dyssynchrony may be preferred for selection. An LV Dyssynchrony can adequately be assessed with TDI, but this has not been compared directly with other imaging modalities. A VE MRI potentially allows direct myocardial wall motion measurements similar to TDI. Methods Twenty patients with heart failure, systolic LV dysfunction, and a wide QRS complex were included, as well as 10 normal individuals with normal QRS duration and LV function. The TDI and VE MRI data were acquired to study Intraventricular Dyssynchrony. Results Left ventricular Dyssynchrony was not observed in normal individuals (mean Dyssynchrony −2 ± 15 ms on TDI; mean −5 ± 17 ms on MRI, p = NS). In patients, mean LV Dyssynchrony was 55 ± 37 ms on TDI; 49 ± 38 ms on MRI (p = NS). Good correlation between both modalities was observed (linear regression TDI = 0.99 × MRI − 5, n = 30, r = 0.98, p Conclusions Both MRI and TDI yield comparable information on LV Dyssynchrony; MRI is useful in the selection of patients for CRT.
-
transvenous biventricular pacing in a child after congenital heart surgery as an alternative therapy for congestive heart failure
Journal of Cardiovascular Electrophysiology, 2003Co-Authors: A Nico M D Blom, Jeroen J Bax, Jaap Ottenkamp, Martin J SchalijAbstract:Transvenous Biventricular Pacing in Children. Cardiac resynchronization therapy improves short-term and long-term hemodynamics in adult patients with congestive heart failure and left bundle branch block. We describe the feasibility of transvenous biventricular pacemaker implantation in a 6-year-old child with heart failure and wide QRS complex after congenital heart surgery. Myocardial tissue Doppler imaging was used to demonstrate Intraventricular Dyssynchrony and resynchronization after cardiac resynchronization therapy. During 1-year follow-up, symptomatology and hemodynamic parameters improved.
Martin J Schalij - One of the best experts on this subject based on the ideXlab platform.
-
effect of cardiac resynchronization therapy in patients without left Intraventricular Dyssynchrony
European Heart Journal, 2012Co-Authors: Gabe B Bleeker, Martin J Schalij, Matteo Bertini, Dominique Auger, See Hooi Ewe, Rutger J. Van Bommel, Tomasz Witkowski, Lieselotvan Van Erven, Jeroen J BaxAbstract:Aims To evaluate the effects of cardiac resynchronization therapy (CRT) on long-term survival of patients without baseline left ventricular (LV) mechanical Dyssynchrony. Methods and results A total of 290 heart failure patients (age 67 ± 10 years, 77% males) without significant baseline LV Dyssynchrony (<60 ms as assessed with tissue Doppler imaging) were treated with CRT. Patients were divided according to the median LV Dyssynchrony measured after 48 h of CRT into two groups. All-cause mortality was compared between the subgroups. In addition, the all-cause mortality rates of these subgroups were compared with the all-cause mortality of 290 heart failure patients treated with CRT who showed significant LV Dyssynchrony (≥60 ms) at baseline. In the group of patients without significant LV Dyssynchrony, median LV Dyssynchrony increased from 22 ms (inter-quartile range 16–34 ms) at baseline to 40 ms (24–56 ms) 48 h after CRT. The cumulative mortality rates at 1-, 2-, and 3-year follow-up of patients with LV Dyssynchrony ≥40 ms 48 h after CRT implantation were significantly higher when compared with patients with LV Dyssynchrony <40 ms (10, 17, and 23 vs. 3, 8, and 10%, respectively; log-rank P < 0.001). Finally, the cumulative mortality rates at 1-, 2-, and 3-year follow-up of patients with baseline LV Dyssynchrony were 3, 8, and 11%, respectively (log-rank P = 0.375 vs. patients with LV Dyssynchrony <40 ms). Induction of LV Dyssynchrony after CRT was an independent predictor of mortality (hazard ratio: 1.247; P = 0.009). Conclusion In patients without significant LV Dyssynchrony, the induction of LV Dyssynchrony after CRT may be related to a less favourable long-term outcome.
-
Effect of cardiac resynchronization therapy in patients without left Intraventricular Dyssynchrony
European heart journal, 2012Co-Authors: Dominique Auger, Gabe B Bleeker, Martin J Schalij, Matteo Bertini, See Hooi Ewe, Rutger J. Van Bommel, Tomasz Witkowski, Lieselotvan Van Erven, Jeroen J BaxAbstract:A total of 290 heart failure patients (age 67+ 10 years, 77% males) without significant baseline LV Dyssynchrony (,60 ms as assessed with tissue Doppler imaging) were treated with CRT. Patients were divided according to the median LV Dyssynchrony measured after 48 h of CRT into two groups. All-cause mortality was compared between the subgroups. In addition, the all-cause mortality rates of these subgroups were compared with the all- cause mortality of 290 heart failure patients treated with CRT who showed significant LV Dyssynchrony (≥60 ms) at baseline. In the group of patients without significant LV Dyssynchrony, median LV Dyssynchrony increased from 22 ms (inter-quartile range 16-34 ms) at baseline to 40 ms (24-56 ms) 48 h after CRT. The cumulative mortality rates at 1-, 2-, and 3-year follow-up of patients with LV Dyssynchrony ≥40 ms 48 h after CRT implantation were sig- nificantly higher when compared with patients with LV Dyssynchrony ,40 ms (10, 17, and 23 vs. 3, 8, and 10%, re- spectively; log-rank P , 0.001). Finally, the cumulative mortality rates at 1-, 2-, and 3-year follow-up of patients with baseline LV Dyssynchrony were 3, 8, and 11%, respectively (log-rank P ¼ 0.375 vs. patients with LV Dyssynchrony ,40 ms). Induction of LV Dyssynchrony after CRT was an independent predictor of mortality (hazard ratio: 1.247; P ¼ 0.009). Conclusion In patients without significant LV Dyssynchrony, the induction of LV Dyssynchrony after CRT may be related to a less
-
Triplane Tissue Doppler Imaging to Evaluate Mechanical Dyssynchrony Before and After Cardiac Resynchronization in a Patient with Congenitally Corrected Transposition of the Great Arteries
Journal of cardiovascular electrophysiology, 2006Co-Authors: Nico R. Van De Veire, Eduard R Holman, Martin J Schalij, Nico A. Blom, Jeroen J BaxAbstract:We report the case of a 13-year-old girl with congenitally corrected transposition of the great arteries. Since the implantation of a conventional pacemaker for acquired complete atrioventricular block, the patient experienced increased heart failure symptoms. Using triplane tissue Doppler imaging, significant Intraventricular Dyssynchrony induced by unilateral pacing and associated with diminished exercise capacity was demonstrated. A biventricular pacemaker was successfully implanted transvenously, leading to synchronous activation of the systemic ventricle and improved exercise capacity.
-
assessment of left ventricular Dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy head to head comparison between tissue doppler imaging and velocity encoded magnetic resonance imaging
Journal of the American College of Cardiology, 2006Co-Authors: Jos J M Westenberg, Eduard R Holman, Hildo J Lamb, Albert De Roos, Gabe B Bleeker, Ernst E Van Der Wall, Martin J Schalij, Rob J Van Der Geest, Johannes H. C. ReiberAbstract:OBJECTIVES: This study sought to compare tissue Doppler imaging (TDI) with velocity-encoded (VE) magnetic resonance imaging (MRI) for left ventricular (LV) Dyssynchrony assessment. BACKGROUND: Cardiac resynchronization therapy (CRT) is proposed for patients with heart failure, depressed LV function, and a wide QRS complex. Selection is based mainly on electrocardiogram criteria, but recent data suggest that Intraventricular Dyssynchrony may be preferred for selection. An LV Dyssynchrony can adequately be assessed with TDI, but this has not been compared directly with other imaging modalities. A VE MRI potentially allows direct myocardial wall motion measurements similar to TDI. METHODS: Twenty patients with heart failure, systolic LV dysfunction, and a wide QRS complex were included, as well as 10 normal individuals with normal QRS duration and LV function. The TDI and VE MRI data were acquired to study Intraventricular Dyssynchrony. RESULTS: Left ventricular Dyssynchrony was not observed in normal individuals (mean Dyssynchrony -2 +/- 15 ms on TDI; mean -5 +/- 17 ms on MRI, p = NS). In patients, mean LV Dyssynchrony was 55 +/- 37 ms on TDI; 49 +/- 38 ms on MRI (p = NS). Good correlation between both modalities was observed (linear regression TDI = 0.99 x MRI - 5, n = 30, r = 0.98, p < 0.01). The MRI showed a small, nonsignificant underestimation of 5 +/- 8 ms compared with TDI. Agreement between MRI and TDI for classification according to severity of LV Dyssynchrony (minimal, intermediate, and extensive) was excellent (kappa +/- SE = 0.96 +/- 0.07, p < 0.01) with 95% of patients classified identical. CONCLUSIONS: Both MRI and TDI yield comparable information on LV Dyssynchrony; MRI is useful in the selection of patients for CRT.
-
assessment of left ventricular Dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy head to head comparison between tissue doppler imaging and velocity encoded magnetic resonance imaging
Journal of the American College of Cardiology, 2006Co-Authors: Jos J M Westenberg, Eduard R Holman, Johannes H. C. Reiber, Hildo J Lamb, Albert De Roos, Gabe B Bleeker, Martin J Schalij, Rob J Van Der Geest, Ernst E Van Der Wall, Jeroen J BaxAbstract:Objectives This study sought to compare tissue Doppler imaging (TDI) with velocity-encoded (VE) magnetic resonance imaging (MRI) for left ventricular (LV) Dyssynchrony assessment. Background Cardiac resynchronization therapy (CRT) is proposed for patients with heart failure, depressed LV function, and a wide QRS complex. Selection is based mainly on electrocardiogram criteria, but recent data suggest that Intraventricular Dyssynchrony may be preferred for selection. An LV Dyssynchrony can adequately be assessed with TDI, but this has not been compared directly with other imaging modalities. A VE MRI potentially allows direct myocardial wall motion measurements similar to TDI. Methods Twenty patients with heart failure, systolic LV dysfunction, and a wide QRS complex were included, as well as 10 normal individuals with normal QRS duration and LV function. The TDI and VE MRI data were acquired to study Intraventricular Dyssynchrony. Results Left ventricular Dyssynchrony was not observed in normal individuals (mean Dyssynchrony −2 ± 15 ms on TDI; mean −5 ± 17 ms on MRI, p = NS). In patients, mean LV Dyssynchrony was 55 ± 37 ms on TDI; 49 ± 38 ms on MRI (p = NS). Good correlation between both modalities was observed (linear regression TDI = 0.99 × MRI − 5, n = 30, r = 0.98, p Conclusions Both MRI and TDI yield comparable information on LV Dyssynchrony; MRI is useful in the selection of patients for CRT.
Gabe B Bleeker - One of the best experts on this subject based on the ideXlab platform.
-
effect of cardiac resynchronization therapy in patients without left Intraventricular Dyssynchrony
European Heart Journal, 2012Co-Authors: Gabe B Bleeker, Martin J Schalij, Matteo Bertini, Dominique Auger, See Hooi Ewe, Rutger J. Van Bommel, Tomasz Witkowski, Lieselotvan Van Erven, Jeroen J BaxAbstract:Aims To evaluate the effects of cardiac resynchronization therapy (CRT) on long-term survival of patients without baseline left ventricular (LV) mechanical Dyssynchrony. Methods and results A total of 290 heart failure patients (age 67 ± 10 years, 77% males) without significant baseline LV Dyssynchrony (<60 ms as assessed with tissue Doppler imaging) were treated with CRT. Patients were divided according to the median LV Dyssynchrony measured after 48 h of CRT into two groups. All-cause mortality was compared between the subgroups. In addition, the all-cause mortality rates of these subgroups were compared with the all-cause mortality of 290 heart failure patients treated with CRT who showed significant LV Dyssynchrony (≥60 ms) at baseline. In the group of patients without significant LV Dyssynchrony, median LV Dyssynchrony increased from 22 ms (inter-quartile range 16–34 ms) at baseline to 40 ms (24–56 ms) 48 h after CRT. The cumulative mortality rates at 1-, 2-, and 3-year follow-up of patients with LV Dyssynchrony ≥40 ms 48 h after CRT implantation were significantly higher when compared with patients with LV Dyssynchrony <40 ms (10, 17, and 23 vs. 3, 8, and 10%, respectively; log-rank P < 0.001). Finally, the cumulative mortality rates at 1-, 2-, and 3-year follow-up of patients with baseline LV Dyssynchrony were 3, 8, and 11%, respectively (log-rank P = 0.375 vs. patients with LV Dyssynchrony <40 ms). Induction of LV Dyssynchrony after CRT was an independent predictor of mortality (hazard ratio: 1.247; P = 0.009). Conclusion In patients without significant LV Dyssynchrony, the induction of LV Dyssynchrony after CRT may be related to a less favourable long-term outcome.
-
Effect of cardiac resynchronization therapy in patients without left Intraventricular Dyssynchrony
European heart journal, 2012Co-Authors: Dominique Auger, Gabe B Bleeker, Martin J Schalij, Matteo Bertini, See Hooi Ewe, Rutger J. Van Bommel, Tomasz Witkowski, Lieselotvan Van Erven, Jeroen J BaxAbstract:A total of 290 heart failure patients (age 67+ 10 years, 77% males) without significant baseline LV Dyssynchrony (,60 ms as assessed with tissue Doppler imaging) were treated with CRT. Patients were divided according to the median LV Dyssynchrony measured after 48 h of CRT into two groups. All-cause mortality was compared between the subgroups. In addition, the all-cause mortality rates of these subgroups were compared with the all- cause mortality of 290 heart failure patients treated with CRT who showed significant LV Dyssynchrony (≥60 ms) at baseline. In the group of patients without significant LV Dyssynchrony, median LV Dyssynchrony increased from 22 ms (inter-quartile range 16-34 ms) at baseline to 40 ms (24-56 ms) 48 h after CRT. The cumulative mortality rates at 1-, 2-, and 3-year follow-up of patients with LV Dyssynchrony ≥40 ms 48 h after CRT implantation were sig- nificantly higher when compared with patients with LV Dyssynchrony ,40 ms (10, 17, and 23 vs. 3, 8, and 10%, re- spectively; log-rank P , 0.001). Finally, the cumulative mortality rates at 1-, 2-, and 3-year follow-up of patients with baseline LV Dyssynchrony were 3, 8, and 11%, respectively (log-rank P ¼ 0.375 vs. patients with LV Dyssynchrony ,40 ms). Induction of LV Dyssynchrony after CRT was an independent predictor of mortality (hazard ratio: 1.247; P ¼ 0.009). Conclusion In patients without significant LV Dyssynchrony, the induction of LV Dyssynchrony after CRT may be related to a less
-
assessment of left ventricular Dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy head to head comparison between tissue doppler imaging and velocity encoded magnetic resonance imaging
Journal of the American College of Cardiology, 2006Co-Authors: Jos J M Westenberg, Eduard R Holman, Hildo J Lamb, Albert De Roos, Gabe B Bleeker, Ernst E Van Der Wall, Martin J Schalij, Rob J Van Der Geest, Johannes H. C. ReiberAbstract:OBJECTIVES: This study sought to compare tissue Doppler imaging (TDI) with velocity-encoded (VE) magnetic resonance imaging (MRI) for left ventricular (LV) Dyssynchrony assessment. BACKGROUND: Cardiac resynchronization therapy (CRT) is proposed for patients with heart failure, depressed LV function, and a wide QRS complex. Selection is based mainly on electrocardiogram criteria, but recent data suggest that Intraventricular Dyssynchrony may be preferred for selection. An LV Dyssynchrony can adequately be assessed with TDI, but this has not been compared directly with other imaging modalities. A VE MRI potentially allows direct myocardial wall motion measurements similar to TDI. METHODS: Twenty patients with heart failure, systolic LV dysfunction, and a wide QRS complex were included, as well as 10 normal individuals with normal QRS duration and LV function. The TDI and VE MRI data were acquired to study Intraventricular Dyssynchrony. RESULTS: Left ventricular Dyssynchrony was not observed in normal individuals (mean Dyssynchrony -2 +/- 15 ms on TDI; mean -5 +/- 17 ms on MRI, p = NS). In patients, mean LV Dyssynchrony was 55 +/- 37 ms on TDI; 49 +/- 38 ms on MRI (p = NS). Good correlation between both modalities was observed (linear regression TDI = 0.99 x MRI - 5, n = 30, r = 0.98, p < 0.01). The MRI showed a small, nonsignificant underestimation of 5 +/- 8 ms compared with TDI. Agreement between MRI and TDI for classification according to severity of LV Dyssynchrony (minimal, intermediate, and extensive) was excellent (kappa +/- SE = 0.96 +/- 0.07, p < 0.01) with 95% of patients classified identical. CONCLUSIONS: Both MRI and TDI yield comparable information on LV Dyssynchrony; MRI is useful in the selection of patients for CRT.
-
assessment of left ventricular Dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy head to head comparison between tissue doppler imaging and velocity encoded magnetic resonance imaging
Journal of the American College of Cardiology, 2006Co-Authors: Jos J M Westenberg, Eduard R Holman, Johannes H. C. Reiber, Hildo J Lamb, Albert De Roos, Gabe B Bleeker, Martin J Schalij, Rob J Van Der Geest, Ernst E Van Der Wall, Jeroen J BaxAbstract:Objectives This study sought to compare tissue Doppler imaging (TDI) with velocity-encoded (VE) magnetic resonance imaging (MRI) for left ventricular (LV) Dyssynchrony assessment. Background Cardiac resynchronization therapy (CRT) is proposed for patients with heart failure, depressed LV function, and a wide QRS complex. Selection is based mainly on electrocardiogram criteria, but recent data suggest that Intraventricular Dyssynchrony may be preferred for selection. An LV Dyssynchrony can adequately be assessed with TDI, but this has not been compared directly with other imaging modalities. A VE MRI potentially allows direct myocardial wall motion measurements similar to TDI. Methods Twenty patients with heart failure, systolic LV dysfunction, and a wide QRS complex were included, as well as 10 normal individuals with normal QRS duration and LV function. The TDI and VE MRI data were acquired to study Intraventricular Dyssynchrony. Results Left ventricular Dyssynchrony was not observed in normal individuals (mean Dyssynchrony −2 ± 15 ms on TDI; mean −5 ± 17 ms on MRI, p = NS). In patients, mean LV Dyssynchrony was 55 ± 37 ms on TDI; 49 ± 38 ms on MRI (p = NS). Good correlation between both modalities was observed (linear regression TDI = 0.99 × MRI − 5, n = 30, r = 0.98, p Conclusions Both MRI and TDI yield comparable information on LV Dyssynchrony; MRI is useful in the selection of patients for CRT.
Johannes H. C. Reiber - One of the best experts on this subject based on the ideXlab platform.
-
assessment of left ventricular Dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy head to head comparison between tissue doppler imaging and velocity encoded magnetic resonance imaging
Journal of the American College of Cardiology, 2006Co-Authors: Jos J M Westenberg, Eduard R Holman, Hildo J Lamb, Albert De Roos, Gabe B Bleeker, Ernst E Van Der Wall, Martin J Schalij, Rob J Van Der Geest, Johannes H. C. ReiberAbstract:OBJECTIVES: This study sought to compare tissue Doppler imaging (TDI) with velocity-encoded (VE) magnetic resonance imaging (MRI) for left ventricular (LV) Dyssynchrony assessment. BACKGROUND: Cardiac resynchronization therapy (CRT) is proposed for patients with heart failure, depressed LV function, and a wide QRS complex. Selection is based mainly on electrocardiogram criteria, but recent data suggest that Intraventricular Dyssynchrony may be preferred for selection. An LV Dyssynchrony can adequately be assessed with TDI, but this has not been compared directly with other imaging modalities. A VE MRI potentially allows direct myocardial wall motion measurements similar to TDI. METHODS: Twenty patients with heart failure, systolic LV dysfunction, and a wide QRS complex were included, as well as 10 normal individuals with normal QRS duration and LV function. The TDI and VE MRI data were acquired to study Intraventricular Dyssynchrony. RESULTS: Left ventricular Dyssynchrony was not observed in normal individuals (mean Dyssynchrony -2 +/- 15 ms on TDI; mean -5 +/- 17 ms on MRI, p = NS). In patients, mean LV Dyssynchrony was 55 +/- 37 ms on TDI; 49 +/- 38 ms on MRI (p = NS). Good correlation between both modalities was observed (linear regression TDI = 0.99 x MRI - 5, n = 30, r = 0.98, p < 0.01). The MRI showed a small, nonsignificant underestimation of 5 +/- 8 ms compared with TDI. Agreement between MRI and TDI for classification according to severity of LV Dyssynchrony (minimal, intermediate, and extensive) was excellent (kappa +/- SE = 0.96 +/- 0.07, p < 0.01) with 95% of patients classified identical. CONCLUSIONS: Both MRI and TDI yield comparable information on LV Dyssynchrony; MRI is useful in the selection of patients for CRT.
-
assessment of left ventricular Dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy head to head comparison between tissue doppler imaging and velocity encoded magnetic resonance imaging
Journal of the American College of Cardiology, 2006Co-Authors: Jos J M Westenberg, Eduard R Holman, Johannes H. C. Reiber, Hildo J Lamb, Albert De Roos, Gabe B Bleeker, Martin J Schalij, Rob J Van Der Geest, Ernst E Van Der Wall, Jeroen J BaxAbstract:Objectives This study sought to compare tissue Doppler imaging (TDI) with velocity-encoded (VE) magnetic resonance imaging (MRI) for left ventricular (LV) Dyssynchrony assessment. Background Cardiac resynchronization therapy (CRT) is proposed for patients with heart failure, depressed LV function, and a wide QRS complex. Selection is based mainly on electrocardiogram criteria, but recent data suggest that Intraventricular Dyssynchrony may be preferred for selection. An LV Dyssynchrony can adequately be assessed with TDI, but this has not been compared directly with other imaging modalities. A VE MRI potentially allows direct myocardial wall motion measurements similar to TDI. Methods Twenty patients with heart failure, systolic LV dysfunction, and a wide QRS complex were included, as well as 10 normal individuals with normal QRS duration and LV function. The TDI and VE MRI data were acquired to study Intraventricular Dyssynchrony. Results Left ventricular Dyssynchrony was not observed in normal individuals (mean Dyssynchrony −2 ± 15 ms on TDI; mean −5 ± 17 ms on MRI, p = NS). In patients, mean LV Dyssynchrony was 55 ± 37 ms on TDI; 49 ± 38 ms on MRI (p = NS). Good correlation between both modalities was observed (linear regression TDI = 0.99 × MRI − 5, n = 30, r = 0.98, p Conclusions Both MRI and TDI yield comparable information on LV Dyssynchrony; MRI is useful in the selection of patients for CRT.
Eduard R Holman - One of the best experts on this subject based on the ideXlab platform.
-
Triplane Tissue Doppler Imaging to Evaluate Mechanical Dyssynchrony Before and After Cardiac Resynchronization in a Patient with Congenitally Corrected Transposition of the Great Arteries
Journal of cardiovascular electrophysiology, 2006Co-Authors: Nico R. Van De Veire, Eduard R Holman, Martin J Schalij, Nico A. Blom, Jeroen J BaxAbstract:We report the case of a 13-year-old girl with congenitally corrected transposition of the great arteries. Since the implantation of a conventional pacemaker for acquired complete atrioventricular block, the patient experienced increased heart failure symptoms. Using triplane tissue Doppler imaging, significant Intraventricular Dyssynchrony induced by unilateral pacing and associated with diminished exercise capacity was demonstrated. A biventricular pacemaker was successfully implanted transvenously, leading to synchronous activation of the systemic ventricle and improved exercise capacity.
-
assessment of left ventricular Dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy head to head comparison between tissue doppler imaging and velocity encoded magnetic resonance imaging
Journal of the American College of Cardiology, 2006Co-Authors: Jos J M Westenberg, Eduard R Holman, Hildo J Lamb, Albert De Roos, Gabe B Bleeker, Ernst E Van Der Wall, Martin J Schalij, Rob J Van Der Geest, Johannes H. C. ReiberAbstract:OBJECTIVES: This study sought to compare tissue Doppler imaging (TDI) with velocity-encoded (VE) magnetic resonance imaging (MRI) for left ventricular (LV) Dyssynchrony assessment. BACKGROUND: Cardiac resynchronization therapy (CRT) is proposed for patients with heart failure, depressed LV function, and a wide QRS complex. Selection is based mainly on electrocardiogram criteria, but recent data suggest that Intraventricular Dyssynchrony may be preferred for selection. An LV Dyssynchrony can adequately be assessed with TDI, but this has not been compared directly with other imaging modalities. A VE MRI potentially allows direct myocardial wall motion measurements similar to TDI. METHODS: Twenty patients with heart failure, systolic LV dysfunction, and a wide QRS complex were included, as well as 10 normal individuals with normal QRS duration and LV function. The TDI and VE MRI data were acquired to study Intraventricular Dyssynchrony. RESULTS: Left ventricular Dyssynchrony was not observed in normal individuals (mean Dyssynchrony -2 +/- 15 ms on TDI; mean -5 +/- 17 ms on MRI, p = NS). In patients, mean LV Dyssynchrony was 55 +/- 37 ms on TDI; 49 +/- 38 ms on MRI (p = NS). Good correlation between both modalities was observed (linear regression TDI = 0.99 x MRI - 5, n = 30, r = 0.98, p < 0.01). The MRI showed a small, nonsignificant underestimation of 5 +/- 8 ms compared with TDI. Agreement between MRI and TDI for classification according to severity of LV Dyssynchrony (minimal, intermediate, and extensive) was excellent (kappa +/- SE = 0.96 +/- 0.07, p < 0.01) with 95% of patients classified identical. CONCLUSIONS: Both MRI and TDI yield comparable information on LV Dyssynchrony; MRI is useful in the selection of patients for CRT.
-
assessment of left ventricular Dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy head to head comparison between tissue doppler imaging and velocity encoded magnetic resonance imaging
Journal of the American College of Cardiology, 2006Co-Authors: Jos J M Westenberg, Eduard R Holman, Johannes H. C. Reiber, Hildo J Lamb, Albert De Roos, Gabe B Bleeker, Martin J Schalij, Rob J Van Der Geest, Ernst E Van Der Wall, Jeroen J BaxAbstract:Objectives This study sought to compare tissue Doppler imaging (TDI) with velocity-encoded (VE) magnetic resonance imaging (MRI) for left ventricular (LV) Dyssynchrony assessment. Background Cardiac resynchronization therapy (CRT) is proposed for patients with heart failure, depressed LV function, and a wide QRS complex. Selection is based mainly on electrocardiogram criteria, but recent data suggest that Intraventricular Dyssynchrony may be preferred for selection. An LV Dyssynchrony can adequately be assessed with TDI, but this has not been compared directly with other imaging modalities. A VE MRI potentially allows direct myocardial wall motion measurements similar to TDI. Methods Twenty patients with heart failure, systolic LV dysfunction, and a wide QRS complex were included, as well as 10 normal individuals with normal QRS duration and LV function. The TDI and VE MRI data were acquired to study Intraventricular Dyssynchrony. Results Left ventricular Dyssynchrony was not observed in normal individuals (mean Dyssynchrony −2 ± 15 ms on TDI; mean −5 ± 17 ms on MRI, p = NS). In patients, mean LV Dyssynchrony was 55 ± 37 ms on TDI; 49 ± 38 ms on MRI (p = NS). Good correlation between both modalities was observed (linear regression TDI = 0.99 × MRI − 5, n = 30, r = 0.98, p Conclusions Both MRI and TDI yield comparable information on LV Dyssynchrony; MRI is useful in the selection of patients for CRT.
