The Experts below are selected from a list of 294 Experts worldwide ranked by ideXlab platform
Michael L. Krychman - One of the best experts on this subject based on the ideXlab platform.
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laxity of the vaginal Introitus after childbirth nonsurgical outpatient procedure for vaginal tissue restoration and improved sexual satisfaction using low energy radiofrequency thermal therapy
Journal of Womens Health, 2013Co-Authors: Yuki Sekiguchi, Yukari Utsugisawa, Yoko Azekosi, Manami Kinjo, Mihyon Song, Yodhinobu Kubota, Sheryl A. Kingsberg, Michael L. KrychmanAbstract:Abstract Introduction: Vaginal childbirth may result in vaginal introital laxity, altered genital sensation during sexual intercourse, and reduced sexual satisfaction. We report the long-term effectiveness of a single nonsurgical procedure with radiofrequency (RF) energy for laxity at the vaginal Introitus. Materials and Methods: Prospective single-arm study of 30 premenopausal women (21–52 year) with one 30-minute office procedure using RF applied to the vaginal Introitus; 12-month outcome assessments included the linguistic validated Japanese versions of the Female Sexual Function Index (FSFI) and Female Sexual Distress Scale-Revised (FSDS-R) and the Vaginal Laxity and Sexual Satisfaction Questionnaires. Results: Sexual function improved significantly throughout 6 months (30 subjects); mean FSFI total score was 22.4±6.7 before treatment and then improved to mean 26.0±5.8 at month 6 (P=0.002), inclusive of improved scores in five of six FSFI domains except desire (P<0.001 –<0.01). In the 22 of 30 subject...
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Laxity of the vaginal Introitus after childbirth: nonsurgical outpatient procedure for vaginal tissue restoration and improved sexual satisfaction using low-energy radiofrequency thermal therapy.
Journal of women's health (2002), 2013Co-Authors: Yuki Sekiguchi, Yukari Utsugisawa, Yoko Azekosi, Manami Kinjo, Mihyon Song, Yodhinobu Kubota, Sheryl A. Kingsberg, Michael L. KrychmanAbstract:Abstract Introduction: Vaginal childbirth may result in vaginal introital laxity, altered genital sensation during sexual intercourse, and reduced sexual satisfaction. We report the long-term effectiveness of a single nonsurgical procedure with radiofrequency (RF) energy for laxity at the vaginal Introitus. Materials and Methods: Prospective single-arm study of 30 premenopausal women (21–52 year) with one 30-minute office procedure using RF applied to the vaginal Introitus; 12-month outcome assessments included the linguistic validated Japanese versions of the Female Sexual Function Index (FSFI) and Female Sexual Distress Scale-Revised (FSDS-R) and the Vaginal Laxity and Sexual Satisfaction Questionnaires. Results: Sexual function improved significantly throughout 6 months (30 subjects); mean FSFI total score was 22.4±6.7 before treatment and then improved to mean 26.0±5.8 at month 6 (P=0.002), inclusive of improved scores in five of six FSFI domains except desire (P
Kate V. Meriwether - One of the best experts on this subject based on the ideXlab platform.
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Repair of colonic neovaginal stenosis using a biological graft in a male-to-female transgender patient
International Urogynecology Journal, 2019Co-Authors: Ankita Gupta, Ryan Stewart, Sean Francis, Deslyn Hobson, Kate V. MeriwetherAbstract:Introduction and hypothesis One in 2900 genotypical men report gender dysphoria, and many undergo gender confirmation surgery to match their physical phenotype to their identity. A variety of surgical techniques are used in male-to-female transgender patients, one of which is bowel vaginoplasty, and postoperative stenosis of the colonic neovagina is common. Extracellular matrix grafts have been used in vaginal reconstruction. with porcine urinary bladder matrix (UBM) acting as a scaffold for smooth-muscle tissue and matrix regeneration. The aim of this surgical video is to describe the use of a UBM biological graft in repair of introital stenosis due to recurrent granulation tissue in the colonic neovagina of a male-to-female transgender patient. Methods A 32-year-old male-to-female transgender patient with a history of rectosigmoid neovagina formation for genital gender confirmation surgery 12 months prior presented with genital granulation tissue and stenosis of her neovaginal Introitus. Despite two surgical revisions, the patient developed recurrence of granulation tissue and obliteration of the neovaginal Introitus, preventing sexual function of the neovagina. Results Reconstruction of the neovaginal Introitus was performed using UBM. The patient noted improvement in comfort, hygiene, and quality of life following the procedure. This video describes our surgical technique and perioperative clinical findings. Conclusions We report the novel use of UBM biological graft in the revision of a neovaginal Introitus after former rectosigmoid vaginoplasty in a male-to-female transgender patient.
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Repair of colonic neovaginal stenosis using a biological graft in a male-to-female transgender patient.
International urogynecology journal, 2018Co-Authors: Ankita Gupta, Sean L. Francis, Ryan Stewart, Deslyn T. G. Hobson, Kate V. MeriwetherAbstract:One in 2900 genotypical men report gender dysphoria, and many undergo gender confirmation surgery to match their physical phenotype to their identity. A variety of surgical techniques are used in male-to-female transgender patients, one of which is bowel vaginoplasty, and postoperative stenosis of the colonic neovagina is common. Extracellular matrix grafts have been used in vaginal reconstruction. with porcine urinary bladder matrix (UBM) acting as a scaffold for smooth-muscle tissue and matrix regeneration. The aim of this surgical video is to describe the use of a UBM biological graft in repair of introital stenosis due to recurrent granulation tissue in the colonic neovagina of a male-to-female transgender patient. A 32-year-old male-to-female transgender patient with a history of rectosigmoid neovagina formation for genital gender confirmation surgery 12 months prior presented with genital granulation tissue and stenosis of her neovaginal Introitus. Despite two surgical revisions, the patient developed recurrence of granulation tissue and obliteration of the neovaginal Introitus, preventing sexual function of the neovagina. Reconstruction of the neovaginal Introitus was performed using UBM. The patient noted improvement in comfort, hygiene, and quality of life following the procedure. This video describes our surgical technique and perioperative clinical findings. We report the novel use of UBM biological graft in the revision of a neovaginal Introitus after former rectosigmoid vaginoplasty in a male-to-female transgender patient.
Yuki Sekiguchi - One of the best experts on this subject based on the ideXlab platform.
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laxity of the vaginal Introitus after childbirth nonsurgical outpatient procedure for vaginal tissue restoration and improved sexual satisfaction using low energy radiofrequency thermal therapy
Journal of Womens Health, 2013Co-Authors: Yuki Sekiguchi, Yukari Utsugisawa, Yoko Azekosi, Manami Kinjo, Mihyon Song, Yodhinobu Kubota, Sheryl A. Kingsberg, Michael L. KrychmanAbstract:Abstract Introduction: Vaginal childbirth may result in vaginal introital laxity, altered genital sensation during sexual intercourse, and reduced sexual satisfaction. We report the long-term effectiveness of a single nonsurgical procedure with radiofrequency (RF) energy for laxity at the vaginal Introitus. Materials and Methods: Prospective single-arm study of 30 premenopausal women (21–52 year) with one 30-minute office procedure using RF applied to the vaginal Introitus; 12-month outcome assessments included the linguistic validated Japanese versions of the Female Sexual Function Index (FSFI) and Female Sexual Distress Scale-Revised (FSDS-R) and the Vaginal Laxity and Sexual Satisfaction Questionnaires. Results: Sexual function improved significantly throughout 6 months (30 subjects); mean FSFI total score was 22.4±6.7 before treatment and then improved to mean 26.0±5.8 at month 6 (P=0.002), inclusive of improved scores in five of six FSFI domains except desire (P<0.001 –<0.01). In the 22 of 30 subject...
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Laxity of the vaginal Introitus after childbirth: nonsurgical outpatient procedure for vaginal tissue restoration and improved sexual satisfaction using low-energy radiofrequency thermal therapy.
Journal of women's health (2002), 2013Co-Authors: Yuki Sekiguchi, Yukari Utsugisawa, Yoko Azekosi, Manami Kinjo, Mihyon Song, Yodhinobu Kubota, Sheryl A. Kingsberg, Michael L. KrychmanAbstract:Abstract Introduction: Vaginal childbirth may result in vaginal introital laxity, altered genital sensation during sexual intercourse, and reduced sexual satisfaction. We report the long-term effectiveness of a single nonsurgical procedure with radiofrequency (RF) energy for laxity at the vaginal Introitus. Materials and Methods: Prospective single-arm study of 30 premenopausal women (21–52 year) with one 30-minute office procedure using RF applied to the vaginal Introitus; 12-month outcome assessments included the linguistic validated Japanese versions of the Female Sexual Function Index (FSFI) and Female Sexual Distress Scale-Revised (FSDS-R) and the Vaginal Laxity and Sexual Satisfaction Questionnaires. Results: Sexual function improved significantly throughout 6 months (30 subjects); mean FSFI total score was 22.4±6.7 before treatment and then improved to mean 26.0±5.8 at month 6 (P=0.002), inclusive of improved scores in five of six FSFI domains except desire (P
Ankita Gupta - One of the best experts on this subject based on the ideXlab platform.
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Repair of colonic neovaginal stenosis using a biological graft in a male-to-female transgender patient
International Urogynecology Journal, 2019Co-Authors: Ankita Gupta, Ryan Stewart, Sean Francis, Deslyn Hobson, Kate V. MeriwetherAbstract:Introduction and hypothesis One in 2900 genotypical men report gender dysphoria, and many undergo gender confirmation surgery to match their physical phenotype to their identity. A variety of surgical techniques are used in male-to-female transgender patients, one of which is bowel vaginoplasty, and postoperative stenosis of the colonic neovagina is common. Extracellular matrix grafts have been used in vaginal reconstruction. with porcine urinary bladder matrix (UBM) acting as a scaffold for smooth-muscle tissue and matrix regeneration. The aim of this surgical video is to describe the use of a UBM biological graft in repair of introital stenosis due to recurrent granulation tissue in the colonic neovagina of a male-to-female transgender patient. Methods A 32-year-old male-to-female transgender patient with a history of rectosigmoid neovagina formation for genital gender confirmation surgery 12 months prior presented with genital granulation tissue and stenosis of her neovaginal Introitus. Despite two surgical revisions, the patient developed recurrence of granulation tissue and obliteration of the neovaginal Introitus, preventing sexual function of the neovagina. Results Reconstruction of the neovaginal Introitus was performed using UBM. The patient noted improvement in comfort, hygiene, and quality of life following the procedure. This video describes our surgical technique and perioperative clinical findings. Conclusions We report the novel use of UBM biological graft in the revision of a neovaginal Introitus after former rectosigmoid vaginoplasty in a male-to-female transgender patient.
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Repair of colonic neovaginal stenosis using a biological graft in a male-to-female transgender patient.
International urogynecology journal, 2018Co-Authors: Ankita Gupta, Sean L. Francis, Ryan Stewart, Deslyn T. G. Hobson, Kate V. MeriwetherAbstract:One in 2900 genotypical men report gender dysphoria, and many undergo gender confirmation surgery to match their physical phenotype to their identity. A variety of surgical techniques are used in male-to-female transgender patients, one of which is bowel vaginoplasty, and postoperative stenosis of the colonic neovagina is common. Extracellular matrix grafts have been used in vaginal reconstruction. with porcine urinary bladder matrix (UBM) acting as a scaffold for smooth-muscle tissue and matrix regeneration. The aim of this surgical video is to describe the use of a UBM biological graft in repair of introital stenosis due to recurrent granulation tissue in the colonic neovagina of a male-to-female transgender patient. A 32-year-old male-to-female transgender patient with a history of rectosigmoid neovagina formation for genital gender confirmation surgery 12 months prior presented with genital granulation tissue and stenosis of her neovaginal Introitus. Despite two surgical revisions, the patient developed recurrence of granulation tissue and obliteration of the neovaginal Introitus, preventing sexual function of the neovagina. Reconstruction of the neovaginal Introitus was performed using UBM. The patient noted improvement in comfort, hygiene, and quality of life following the procedure. This video describes our surgical technique and perioperative clinical findings. We report the novel use of UBM biological graft in the revision of a neovaginal Introitus after former rectosigmoid vaginoplasty in a male-to-female transgender patient.
William J. Ledger - One of the best experts on this subject based on the ideXlab platform.
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investigation of the sensitivity of a cross polarized light visualization system to detect subclinical erythema and dryness in women with vulvovaginitis
American Journal of Obstetrics and Gynecology, 2009Co-Authors: Miranda A. Farage, Mukul Singh, William J. LedgerAbstract:Objective An enhanced visualization technique using polarized light (Syris v600 enhanced visualization system; Syris Scientific LLC, Gray, ME) detects surface and subsurface (≈1 mm depth) inflammation. We sought to compare the Syris v600 system with unaided visual inspection and colposcopy of the female genitalia. Study Design Erythema and dryness of the vulva, Introitus, vagina, and cervix were visualized and scored by each method in patients with and without vulvitis. Results Subsurface visualization was more sensitive in detecting genital erythema and dryness at all sites whether or not symptoms were present. Subsurface inflammation of the Introitus, vagina, and cervix only was detected uniquely in women with vulvar vestibulitis syndrome (VVS). A subset of women presenting with VVS exhibited subclinical inflammation of the vulva vestibule and vagina (designated VVS/lichen sclerosus subgroup). Conclusion Enhanced visualization of the genital epithelial subsurface with cross-polarized light may assist in diagnosing subclinical inflammation in vulvar conditions heretofore characterized as sensory syndromes.
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Investigation of the sensitivity of a cross-polarized light visualization system to detect subclinical erythema and dryness in women with vulvovaginitis.
American journal of obstetrics and gynecology, 2009Co-Authors: Miranda A. Farage, Mukul Singh, William J. LedgerAbstract:An enhanced visualization technique using polarized light (Syris v600 enhanced visualization system; Syris Scientific LLC, Gray, ME) detects surface and subsurface ( approximately 1 mm depth) inflammation. We sought to compare the Syris v600 system with unaided visual inspection and colposcopy of the female genitalia. Erythema and dryness of the vulva, Introitus, vagina, and cervix were visualized and scored by each method in patients with and without vulvitis. Subsurface visualization was more sensitive in detecting genital erythema and dryness at all sites whether or not symptoms were present. Subsurface inflammation of the Introitus, vagina, and cervix only was detected uniquely in women with vulvar vestibulitis syndrome (VVS). A subset of women presenting with VVS exhibited subclinical inflammation of the vulva vestibule and vagina (designated VVS/lichen sclerosus subgroup). Enhanced visualization of the genital epithelial subsurface with cross-polarized light may assist in diagnosing subclinical inflammation in vulvar conditions heretofore characterized as sensory syndromes.
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Human papillomavirus in the vaginal Introitus in women infected with the human immunodeficiency virus.
International journal of STD & AIDS, 2000Co-Authors: Iara M. Linhares, Steven S. Witkin, Maria Eugenia Caetano, Paulo César Giraldo, José Aristodemo Pinotti, William J. LedgerAbstract:The report on Ureaplasma urealyticum in the vaginal Introitus of HIV-infected women and its relation to circulating HIV RNA levels has prompted the authors to examine the same subjects for introital levels of human papillomavirus (HPV). Genital HPV infections occur with high prevalence in HIV-infected women. Paired introital and cervical specimens from 52 consecutive diagnosed and untreated HIV-seropositive women were tested using degenerate consensus primer pairs to the conserved L1 gene. Findings show that 36 (69.2%) of the cervical specimens were positive for HPV. The virus was detected in the Introitus in 21 (58.4%) of the women positive for cervical HPV. HIV-1 RNA levels greater than 10000 copies/ml were identified in the circulation of 14 (26.9%) women; 9 (64.3%) of these women had HPV identified in the Introitus. HIV-1 RNA levels greater than 1000 copies/ml were present in 29 (55.8%) women; 23 (79.3%) of them with introital HPV. Moreover it was suggested that HIV-infected women with HPV in the Introitus might need more frequent monitoring for other infections and a possible malignancy as compared with women whose introital specimens were negative for HPV.
