Ipomoea Aquatica

14,000,000 Leading Edge Experts on the ideXlab platform

Scan Science and Technology

Contact Leading Edge Experts & Companies

Scan Science and Technology

Contact Leading Edge Experts & Companies

The Experts below are selected from a list of 1629 Experts worldwide ranked by ideXlab platform

E R Jansz - One of the best experts on this subject based on the ideXlab platform.

  • Oral hypoglycaemic activity of Ipomoea Aquatica in streptozotocin-induced, diabetic wistar rats and Type II diabetics.
    Phytotherapy research : PTR, 2003
    Co-Authors: T.sugandhika Malalavidhane, S M D N Wickramasinghe, M. S. A. Perera, E R Jansz
    Abstract:

    Ipomoea Aquatica Forsk is a common green leafy vegetable consumed in many parts of the world. The present study was designed to investigate the oral hypoglycaemic activity of Ipomea Aquatica in streptozotocin induced diabetic Wistar rats, and Type II diabetic patients. Experimental diabetes was induced with streptozotocin in Wistar rats. The rats were then divided into test and control groups. In addition to the standard feed given to both groups the test was fed with the shredded leaves of Ipomoea Aquatica (3.4 g/kg) for one week. Type II diabetic patients were subjected to a glucose challenge before and after a single dose of blended I. Aquatica. Patients acted as their own controls. The results revealed that consumption of the shredded, fresh, edible portion of I. Aquatica for one week, effectively reduced the fasting blood sugar level of streptozotocin-induced diabetic rats (p = 0.01). When subjected to a glucose challenge, the Type II diabetic subjects showed a significant reduction (p = 0.001) in the serum glucose concentration 2 h after the glucose load. However, it was not significantly reduced at 1 h (p < 0.09) post glucose load. There was a 29.4% decrease in the serum glucose concentration of the diabetic patients when treated with the plant extract. Copyright © 2003 John Wiley & Sons, Ltd.

  • an aqueous extract of the green leafy vegetable Ipomoea Aquatica is as effective as the oral hypoglycaemic drug tolbutamide in reducing the blood sugar levels of wistar rats
    Phytotherapy Research, 2001
    Co-Authors: S Malalavidhane, S M D N Wickramasinghe, E R Jansz
    Abstract:

    This study was undertaken to compare the oral hypoglycaemic activity of an aqueous extract of the green leafy vegetable Ipomoea Aquatica (dose equivalent to 3.3 g starting material /kg body weight) with that of the known oral hypoglycaemic drug tolbutamide (15 mg/kg body weight) in glucose challenged Wistar rats (3 g/kg body weight, administered 30 min after the administration of Ipomoea Aquatica or tolbutamide). One and half hours after administration of glucose (equivalent to 2 h after administration of plant extract or tolbutamide), the mean blood glucose level of the Ipomoea Aquatica treated group was 47.5% lower than that of the control group treated with distilled water. The tolbutamide treated group showed a mean blood glucose level which was only 33.8% lower than that of the control group. However, statistical analysis indicated that the blood glucose levels of the Ipomoea Aquatica treated group were not significantly different from that of the tolbutamide treated group. Our results show that the aqueous extract of Ipomoea Aquatica is as effectve as tolbutamide in reducing the blood glucose levels of glucose-challenged Wistar rats. Copyright © 2001 John Wiley & Sons, Ltd.

  • oral hypoglycaemic activity of Ipomoea Aquatica
    Journal of Ethnopharmacology, 2000
    Co-Authors: S Malalavidhane, S Nalinie M D Wickramasinghe, E R Jansz
    Abstract:

    Ipomoea Aquatica is a commonly consumed green leafy vegetable in Sri Lanka which is supposed to possess an insulin-like activity [Jayaweera, D.M.A., 1982. Medicinal Plants (Indigenous and Exotic) Used in Ceylon. Part 11. National Science Council, Colombo, Sri Lanka, pp. 99]. Only a little attention has been paid to the therapeutic use of this plant. We studied the oral hypoglycaemic activity of single and multiple doses of I. Aquatica in healthy, male Wistar rats after a glucose challenge. There was a significant reduction in the serum glucose concentrations with both single (33%, P<0.0027) and multiple (25%, P<0.02) doses. The optimum dose was 3.4 g/kg while the optimum activity was given 2 h after the administration of the extract. The present study indicates that a boiled, whole extract of I. Aquatica exerts an oral hypoglycaemic effect in healthy, male, Wistar rats after a glucose challenge.

  • Oral hypoglycaemic activity of Ipomoea Aquatica
    Journal of Ethnopharmacology, 2000
    Co-Authors: T.sugandhika Malalavidhane, S.m.d.nalinie Wickramasinghe, E R Jansz
    Abstract:

    Ipomoea Aquatica is a commonly consumed green leafy vegetable in Sri Lanka which is supposed to possess an insulin-like activity [Jayaweera, D.M.A., 1982. Medicinal Plants (Indigenous and Exotic) Used in Ceylon. Part 11. National Science Council, Colombo, Sri Lanka, pp. 99]. Only a little attention has been paid to the therapeutic use of this plant. We studied the oral hypoglycaemic activity of single and multiple doses of I. Aquatica in healthy, male Wistar rats after a glucose challenge. There was a significant reduction in the serum glucose concentrations with both single (33%, P

A Hadi - One of the best experts on this subject based on the ideXlab platform.

  • Ipomoea Aquatica extract shows protective action against thioacetamide induced hepatotoxicity
    Molecules, 2012
    Co-Authors: Salim S Alkiyumi, Mahmood Ameen Abdullah, Ahmed S Alrashdi, Suzy M Salama, Siddig Ibrahim Abdelwahab, Abdul Hamid, A Hadi
    Abstract:

    In the Indian system of traditional medicine (Ayurveda) it is recommended to consume Ipomoea Aquatica to mitigate disorders like jaundice. In this study, the protective effects of ethanol extract of I. Aquatica against liver damage were evaluated in thioacetamide (TAA)-induced chronic hepatotoxicity in rats. There was no sign of toxicity in the acute toxicity study, in which Sprague-Dawley (SD) rats were orally fed with I. Aquatica (250 and 500 mg/kg) for two months along with administration of TAA (i.p injection 200 mg/kg three times a week for two months). The results showed that the treatment of I. Aquatica significantly lowered the TAA-induced serum levels of hepatic enzyme markers (ALP, ALT, AST, protein, albumin, bilirubin and prothrombin time). The hepatic content of activities and expressions SOD and CAT that were reduced by TAA were brought back to control levels by the plant extract supplement. Meanwhile, the rise in MDA level in the TAA receiving groups also were significantly reduced by I. Aquatica treatment. Histopathology of hepatic tissues by H&E and Masson trichrome stains displayed that I. Aquatica has reduced the incidence of liver lesions, including hepatic cells cloudy swelling, infiltration, hepatic necrosis, and fibrous connective tissue proliferation induced by TAA in rats. Therefore, the results of this study show that the protective effect of I. Aquatica in TAA-induced liver damage might be contributed to its modulation on detoxification enzymes and its antioxidant and free radical

  • Ipomoea Aquatica Extract Shows Protective Action Against Thioacetamide-Induced Hepatotoxicity
    Molecules (Basel Switzerland), 2012
    Co-Authors: Salim S Alkiyumi, Mahmood Ameen Abdullah, Ahmed S Alrashdi, Suzy M Salama, Siddig Ibrahim Abdelwahab, Abdul Hamid, A Hadi
    Abstract:

    In the Indian system of traditional medicine (Ayurveda) it is recommended to consume Ipomoea Aquatica to mitigate disorders like jaundice. In this study, the protective effects of ethanol extract of I. Aquatica against liver damage were evaluated in thioacetamide (TAA)-induced chronic hepatotoxicity in rats. There was no sign of toxicity in the acute toxicity study, in which Sprague-Dawley (SD) rats were orally fed with I. Aquatica (250 and 500 mg/kg) for two months along with administration of TAA (i.p injection 200 mg/kg three times a week for two months). The results showed that the treatment of I. Aquatica significantly lowered the TAA-induced serum levels of hepatic enzyme markers (ALP, ALT, AST, protein, albumin, bilirubin and prothrombin time). The hepatic content of activities and expressions SOD and CAT that were reduced by TAA were brought back to control levels by the plant extract supplement. Meanwhile, the rise in MDA level in the TAA receiving groups also were significantly reduced by I. Aquatica treatment. Histopathology of hepatic tissues by H&E and Masson trichrome stains displayed that I. Aquatica has reduced the incidence of liver lesions, including hepatic cells cloudy swelling, infiltration, hepatic necrosis, and fibrous connective tissue proliferation induced by TAA in rats. Therefore, the results of this study show that the protective effect of I. Aquatica in TAA-induced liver damage might be contributed to its modulation on detoxification enzymes and its antioxidant and free radical scavenger effects. Moreover, it confirms a scientific basis for the traditional use of I. Aquatica for the treatment of liver disorders.

Guo-ping Sheng - One of the best experts on this subject based on the ideXlab platform.

  • Nitrogen removal from eutrophic water by floating-bed-grown water spinach (Ipomoea Aquatica Forsk.) with ion implantation.
    Water research, 2007
    Co-Authors: Guo-ping Sheng
    Abstract:

    The aim of this study was to investigate the use of water spinach (Ipomoea Aquatica Forsk.) with N(+) ion-beam implantation for removal of nutrient species from eutrophic water. The mutated water spinach was grown on floating beds, and growth chambers were used to examine the growth of three cultivars of water spinach with ion implantation for 14 days in simulated eutrophic water at both high and low nitrogen levels. The specific weight growth rates of three cultivars of water spinach with ion implantation were significantly higher than the control, and their NO(3)-N and NH(4)-N removal efficiencies were also greater than those of the control. Furthermore, compared with the control, the nitrogen contents in the plant biomass with ion implantation were higher as well.

S Malalavidhane - One of the best experts on this subject based on the ideXlab platform.

  • an aqueous extract of the green leafy vegetable Ipomoea Aquatica is as effective as the oral hypoglycaemic drug tolbutamide in reducing the blood sugar levels of wistar rats
    Phytotherapy Research, 2001
    Co-Authors: S Malalavidhane, S M D N Wickramasinghe, E R Jansz
    Abstract:

    This study was undertaken to compare the oral hypoglycaemic activity of an aqueous extract of the green leafy vegetable Ipomoea Aquatica (dose equivalent to 3.3 g starting material /kg body weight) with that of the known oral hypoglycaemic drug tolbutamide (15 mg/kg body weight) in glucose challenged Wistar rats (3 g/kg body weight, administered 30 min after the administration of Ipomoea Aquatica or tolbutamide). One and half hours after administration of glucose (equivalent to 2 h after administration of plant extract or tolbutamide), the mean blood glucose level of the Ipomoea Aquatica treated group was 47.5% lower than that of the control group treated with distilled water. The tolbutamide treated group showed a mean blood glucose level which was only 33.8% lower than that of the control group. However, statistical analysis indicated that the blood glucose levels of the Ipomoea Aquatica treated group were not significantly different from that of the tolbutamide treated group. Our results show that the aqueous extract of Ipomoea Aquatica is as effectve as tolbutamide in reducing the blood glucose levels of glucose-challenged Wistar rats. Copyright © 2001 John Wiley & Sons, Ltd.

  • oral hypoglycaemic activity of Ipomoea Aquatica
    Journal of Ethnopharmacology, 2000
    Co-Authors: S Malalavidhane, S Nalinie M D Wickramasinghe, E R Jansz
    Abstract:

    Ipomoea Aquatica is a commonly consumed green leafy vegetable in Sri Lanka which is supposed to possess an insulin-like activity [Jayaweera, D.M.A., 1982. Medicinal Plants (Indigenous and Exotic) Used in Ceylon. Part 11. National Science Council, Colombo, Sri Lanka, pp. 99]. Only a little attention has been paid to the therapeutic use of this plant. We studied the oral hypoglycaemic activity of single and multiple doses of I. Aquatica in healthy, male Wistar rats after a glucose challenge. There was a significant reduction in the serum glucose concentrations with both single (33%, P<0.0027) and multiple (25%, P<0.02) doses. The optimum dose was 3.4 g/kg while the optimum activity was given 2 h after the administration of the extract. The present study indicates that a boiled, whole extract of I. Aquatica exerts an oral hypoglycaemic effect in healthy, male, Wistar rats after a glucose challenge.

S M D N Wickramasinghe - One of the best experts on this subject based on the ideXlab platform.

  • Oral hypoglycaemic activity of Ipomoea Aquatica in streptozotocin-induced, diabetic wistar rats and Type II diabetics.
    Phytotherapy research : PTR, 2003
    Co-Authors: T.sugandhika Malalavidhane, S M D N Wickramasinghe, M. S. A. Perera, E R Jansz
    Abstract:

    Ipomoea Aquatica Forsk is a common green leafy vegetable consumed in many parts of the world. The present study was designed to investigate the oral hypoglycaemic activity of Ipomea Aquatica in streptozotocin induced diabetic Wistar rats, and Type II diabetic patients. Experimental diabetes was induced with streptozotocin in Wistar rats. The rats were then divided into test and control groups. In addition to the standard feed given to both groups the test was fed with the shredded leaves of Ipomoea Aquatica (3.4 g/kg) for one week. Type II diabetic patients were subjected to a glucose challenge before and after a single dose of blended I. Aquatica. Patients acted as their own controls. The results revealed that consumption of the shredded, fresh, edible portion of I. Aquatica for one week, effectively reduced the fasting blood sugar level of streptozotocin-induced diabetic rats (p = 0.01). When subjected to a glucose challenge, the Type II diabetic subjects showed a significant reduction (p = 0.001) in the serum glucose concentration 2 h after the glucose load. However, it was not significantly reduced at 1 h (p < 0.09) post glucose load. There was a 29.4% decrease in the serum glucose concentration of the diabetic patients when treated with the plant extract. Copyright © 2003 John Wiley & Sons, Ltd.

  • an aqueous extract of the green leafy vegetable Ipomoea Aquatica is as effective as the oral hypoglycaemic drug tolbutamide in reducing the blood sugar levels of wistar rats
    Phytotherapy Research, 2001
    Co-Authors: S Malalavidhane, S M D N Wickramasinghe, E R Jansz
    Abstract:

    This study was undertaken to compare the oral hypoglycaemic activity of an aqueous extract of the green leafy vegetable Ipomoea Aquatica (dose equivalent to 3.3 g starting material /kg body weight) with that of the known oral hypoglycaemic drug tolbutamide (15 mg/kg body weight) in glucose challenged Wistar rats (3 g/kg body weight, administered 30 min after the administration of Ipomoea Aquatica or tolbutamide). One and half hours after administration of glucose (equivalent to 2 h after administration of plant extract or tolbutamide), the mean blood glucose level of the Ipomoea Aquatica treated group was 47.5% lower than that of the control group treated with distilled water. The tolbutamide treated group showed a mean blood glucose level which was only 33.8% lower than that of the control group. However, statistical analysis indicated that the blood glucose levels of the Ipomoea Aquatica treated group were not significantly different from that of the tolbutamide treated group. Our results show that the aqueous extract of Ipomoea Aquatica is as effectve as tolbutamide in reducing the blood glucose levels of glucose-challenged Wistar rats. Copyright © 2001 John Wiley & Sons, Ltd.