The Experts below are selected from a list of 279 Experts worldwide ranked by ideXlab platform
Peter Metz - One of the best experts on this subject based on the ideXlab platform.
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Enantioselective Total Synthesis of Natural Isoflavans: Asymmetric Transfer Hydrogenation/Deoxygenation of Isoflavanones with Dynamic Kinetic Resolution.
Organic letters, 2018Co-Authors: Anton Keßberg, Tilo Lübken, Peter MetzAbstract:A concise and highly enantioselective synthesis of structurally diverse isoflavans from a single chromone is described. The key transformation is a single-step conversion of racemic Isoflavanones into virtually enantiopure isoflavans by domino asymmetric transfer hydrogenation/deoxygenation with dynamic kinetic resolution.
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enantioselective total synthesis of natural isoflavans asymmetric transfer hydrogenation deoxygenation of Isoflavanones with dynamic kinetic resolution
Organic Letters, 2018Co-Authors: Anton Kesberg, Tilo Lübken, Peter MetzAbstract:A concise and highly enantioselective synthesis of structurally diverse isoflavans from a single chromone is described. The key transformation is a single-step conversion of racemic Isoflavanones into virtually enantiopure isoflavans by domino asymmetric transfer hydrogenation/deoxygenation with dynamic kinetic resolution.
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Enantioselective Total Synthesis of Natural Isoflavans: Asymmetric Transfer Hydrogenation/Deoxygenation of Isoflavanones with Dynamic Kinetic Resolution
2018Co-Authors: Anton Keßberg, Tilo Lübken, Peter MetzAbstract:A concise and highly enantioselective synthesis of structurally diverse isoflavans from a single chromone is described. The key transformation is a single-step conversion of racemic Isoflavanones into virtually enantiopure isoflavans by domino asymmetric transfer hydrogenation/deoxygenation with dynamic kinetic resolution
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Enantioselective Synthesis of Isoflavanones by Catalytic Dynamic Kinetic Resolution
Organic letters, 2017Co-Authors: Tao Qin, Peter MetzAbstract:A ruthenium-catalyzed asymmetric transfer hydrogenation of racemic Isoflavanones with dynamic kinetic resolution yields virtually enantiopure isoflavanols as single diastereomers. Subsequent oxidation gives rise to Isoflavanones in high enantiomeric purities.
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Enantioselective Synthesis of Isoflavanones by Catalytic Dynamic Kinetic Resolution
2017Co-Authors: Tao Qin, Peter MetzAbstract:A ruthenium-catalyzed asymmetric transfer hydrogenation of racemic Isoflavanones with dynamic kinetic resolution yields virtually enantiopure isoflavanols as single diastereomers. Subsequent oxidation gives rise to Isoflavanones in high enantiomeric purities
Tilo Lübken - One of the best experts on this subject based on the ideXlab platform.
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Enantioselective Total Synthesis of Natural Isoflavans: Asymmetric Transfer Hydrogenation/Deoxygenation of Isoflavanones with Dynamic Kinetic Resolution.
Organic letters, 2018Co-Authors: Anton Keßberg, Tilo Lübken, Peter MetzAbstract:A concise and highly enantioselective synthesis of structurally diverse isoflavans from a single chromone is described. The key transformation is a single-step conversion of racemic Isoflavanones into virtually enantiopure isoflavans by domino asymmetric transfer hydrogenation/deoxygenation with dynamic kinetic resolution.
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enantioselective total synthesis of natural isoflavans asymmetric transfer hydrogenation deoxygenation of Isoflavanones with dynamic kinetic resolution
Organic Letters, 2018Co-Authors: Anton Kesberg, Tilo Lübken, Peter MetzAbstract:A concise and highly enantioselective synthesis of structurally diverse isoflavans from a single chromone is described. The key transformation is a single-step conversion of racemic Isoflavanones into virtually enantiopure isoflavans by domino asymmetric transfer hydrogenation/deoxygenation with dynamic kinetic resolution.
Anton Keßberg - One of the best experts on this subject based on the ideXlab platform.
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Enantioselective Total Synthesis of Natural Isoflavans: Asymmetric Transfer Hydrogenation/Deoxygenation of Isoflavanones with Dynamic Kinetic Resolution.
Organic letters, 2018Co-Authors: Anton Keßberg, Tilo Lübken, Peter MetzAbstract:A concise and highly enantioselective synthesis of structurally diverse isoflavans from a single chromone is described. The key transformation is a single-step conversion of racemic Isoflavanones into virtually enantiopure isoflavans by domino asymmetric transfer hydrogenation/deoxygenation with dynamic kinetic resolution.
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Enantioselective Total Synthesis of Natural Isoflavans: Asymmetric Transfer Hydrogenation/Deoxygenation of Isoflavanones with Dynamic Kinetic Resolution
2018Co-Authors: Anton Keßberg, Tilo Lübken, Peter MetzAbstract:A concise and highly enantioselective synthesis of structurally diverse isoflavans from a single chromone is described. The key transformation is a single-step conversion of racemic Isoflavanones into virtually enantiopure isoflavans by domino asymmetric transfer hydrogenation/deoxygenation with dynamic kinetic resolution
Corrado Galeffi - One of the best experts on this subject based on the ideXlab platform.
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prenylated isoflavonoids from millettia pervilleana
Phytochemistry, 2003Co-Authors: Giovanna Palazzino, Elena Federici, Philippe Rasoanaivo, Marcello Nicoletti, Corrado GaleffiAbstract:Abstract From the root bark of Millettia pervilleana , which had shown significant cytotoxic activity, a 3-phenylcoumarin, named pervilleanine, two new pterocarpans, pervilline and pervillinine, and one known, emoroidocarpan, were isolated in addition to rotenone and 3α-hydroxyrotenone. The anticancer activity of two previously isolated Isoflavanones, pervilleanone and 3′- O -demethylpervilleanone is reported.
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Prenylated isoflavonoids from Millettia pervilleana
'Elsevier BV', 2003Co-Authors: Giovanna Palazzino, Elena Federici, Philippe Rasoanaivo, Marcello Nicoletti, Corrado GaleffiAbstract:From the root bark of Millettia pervilleana, which had shown significant cytotoxic activity, a 3-phenylcoumarin, named pervilleanine, two new pterocarpans, pervilline and pervillinine, and one known, emoroidocarpan, were isolated in addition to rotenone and 3alpha-hydroxyrotenone. The anticancer activity of two previously isolated Isoflavanones, pervilleanone and 3'-O-demethylpervilleanone is reported. (C) 2003 Elsevier Science Ltd. All rights reserved
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Two prenylated Isoflavanones from Millettia pervilleana
Phytochemistry, 1997Co-Authors: Corrado Galeffi, Philippe Rasoanaivo, Elena Federici, Giovanna Palazzino, Marcello Nicoletti, Benoı̂t RasolondratovoAbstract:Abstract From the root bark of Millettia pervilleana , which showed high cytotoxic activity, two prenylated Isoflavanones were isolated. Their structures were determined by means of chemical and spectroscopic properties to be (3 R )-2′,7-dihydroxy-3′,4′-dimethoxy-5′- α , α -dimethylallylisoflavanone, named pervilleanone, and its 3′- O -demethyl derivative.
Munekazu Iinuma - One of the best experts on this subject based on the ideXlab platform.
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Four Isoflavanones from roots of Sophora tetraptera
Phytochemistry, 1999Co-Authors: Yoshiaki Shirataki, Satoko Matsuoka, Manki Komatsu, Masayoshi Ohyama, Toshiyuki Tanaka, Munekazu IinumaAbstract:Four new Isoflavanones, tetrapterols F–I, were isolated from roots of Sophora tetraptera in addition to seven known flavonoids, lupinifolin, 8-O-methylretusin, 5,7,4′-trihydroxy-6,3′-di(γ,γ-dimethylallyl)isoflavone, (−)-maackiain, sophoracarpan A, medicagol and 2-(2,4-dihydroxyphenyl)-5,6-methylenedioxybenzofuran. The structure of the new Isoflavanones was determined to be 3,5,7–trihydroxy-2′-methoxy-8-γ,γ-dimethylallyl-6‴,6‴-dimethylpyrano[2‴,3‴:4′,3′]isoflavanone(tetrapterol F), 5,7,2′,4′-tetrahydroxy-6,5′-di(γ,γ-dimethylallyl)isoflavanone(tetrapterol G), 5,7,2′–trihydroxy–4′–methoxy-8,5′-di(γ,γ-dimethylallyl) isoflavanone(tetrapterol H) and 7,4′-dihydroxy-6,3′-di(γ,γ-dimethylallyl)isoflavanone (tetrapterol I) by means of spectroscopic analysis.
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Flavonoid compounds in roots of Sophora tetraptera
Phytochemistry, 1995Co-Authors: Munekazu Iinuma, Masayoshi Ohyama, Yoko Kawasaka, Toshiyuki TanakaAbstract:Abstract Two novel flavonoid compounds, an isoflavanone, tetrapterol A, and a pterocarpan, tetrapterol B, and three new Isoflavanones, tetrapterols C-E, were isolated from the roots of Sophora tetraptera , in addition to eight known phenolic compounds (kenusanone A, lespedeol B, euchenone a 9 , lonchocarpol A, cajanone, (−)-maackiain, isoneorautenol and pentacosanyl caffeate). The two novel compounds had a common characteristic partial structure which is derived from a geranyl group which forms a new aromatic ring after cyclization with a hydroxyl group located at a side ring in a flavonoid framework and dehydrogenation. The new Isoflavanones had a geranyl or an isoprenyl group on their A or B ring. The structures were determined by analysis of spectral data, in particular, 2D-NMR.
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Three Isoflavanones from roots ofSophora prostrata
Phytochemistry, 1994Co-Authors: Munekazu Iinuma, Masayoshi Ohyama, Toshiyuki TanakaAbstract:Abstract Three new Isoflavanones, named prostratols A–C, were isolated from the roots of Sophora prostrata . The structures were confirmed by means of spec
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An isoflavanone from roots of Echinosophora koreensis
Phytochemistry, 1991Co-Authors: Munekazu Iinuma, Masayoshi Ohyama, Toshiyuki Tanaka, Mizuo Mizuno, Soon-keun HongAbstract:Abstract In addition to known phenolic compounds, medicarpin, maackiain, echinoisoflavanone and echinoisosophoranone, a new isoflavanone named kenusanone A was isolated from the roots of Echinosophora koreensis . The structure was determined to be 5′-geranyl-5,7,2′,4′-tetrahydroxyisoflavanone by means of spectroscopic analysis.
