The Experts below are selected from a list of 48 Experts worldwide ranked by ideXlab platform
Hochul Shin - One of the best experts on this subject based on the ideXlab platform.
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quantification of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle beef milk egg shrimp flatfish and eel using a simplified extraction method coupled with liquid chromatography triple quadrupole tandem mass spectrometry
Journal of Chromatography B, 2017Co-Authors: Jina Park, N A Afifi, Byungjoon Chang, Weijia Zheng, Jeongmin Choi, Hee Yi, Jaehan Shim, A Abd M Elaty, Hochul ShinAbstract:Abstract In this study, a simple analytical approach has been developed and validated for the determination of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle, beef, milk, egg, shrimp, flatfish, and eel using liquid chromatography-tandem mass spectrometry (LC–MS/MS). A 0.1% solution of acetic acid in acetonitrile combined with n-hexane was used for deproteinization and defatting of all tested matrices and the target drugs were well separated on a Waters Xbridge™ C18 analytical column using a mobile phase consisting of 0.1% acetic acid (A) and 0.1% solution of acetic acid in methanol (B). The linearity estimated from six-point matrix-matched calibrations was good, with coefficients of determination ≥0.9873. The limits of quantification (LOQs) for bupivacaine hydrochloride and Isoflupredone Acetate were 1 and 2 ng g−1, respectively. Recovery percentages in the ranges of 72.51–112.39% (bupivacaine hydrochloride) and 72.58–114.56% (Isoflupredone Acetate) were obtained from three different fortification concentrations with relative standard deviations (RSDs) of
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quantification of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle beef milk egg shrimp flatfish and eel using a simplified extraction method coupled with liquid chromatography triple quadrupole tandem mass spectrometry
Journal of Chromatography A, 2017Co-Authors: Jina Park, N A Afifi, Byungjoon Chang, Weijia Zheng, Jeongmin Choi, Hee Yi, Jaehan Shim, A Abd M Elaty, Hochul ShinAbstract:In this study, a simple analytical approach has been developed and validated for the determination of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle, beef, milk, egg, shrimp, flatfish, and eel using liquid chromatography-tandem mass spectrometry (LC–MS/MS). A 0.1% solution of acetic acid in acetonitrile combined with n-hexane was used for deproteinization and defatting of all tested matrices and the target drugs were well separated on a Waters Xbridge™ C18 analytical column using a mobile phase consisting of 0.1% acetic acid (A) and 0.1% solution of acetic acid in methanol (B). The linearity estimated from six-point matrix-matched calibrations was good, with coefficients of determination ≥0.9873. The limits of quantification (LOQs) for bupivacaine hydrochloride and Isoflupredone Acetate were 1 and 2ngg⁻¹, respectively. Recovery percentages in the ranges of 72.51–112.39% (bupivacaine hydrochloride) and 72.58–114.56% (Isoflupredone Acetate) were obtained from three different fortification concentrations with relative standard deviations (RSDs) of <15.14%. All samples for the experimental work and method application were collected from the local markets in Seoul, Republic of Korea, and none of them tested positive for the target drugs. In conclusion, a simple method using a 0.1% solution of acetic acid in acetonitrile and n-hexane followed by LC–MS/MS could effectively extract bupivacaine hydrochloride and Isoflupredone Acetate from porcine muscle, beef, milk, egg, shrimp, flatfish, and eel samples.
A Abd M Elaty - One of the best experts on this subject based on the ideXlab platform.
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quantification of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle beef milk egg shrimp flatfish and eel using a simplified extraction method coupled with liquid chromatography triple quadrupole tandem mass spectrometry
Journal of Chromatography B, 2017Co-Authors: Jina Park, N A Afifi, Byungjoon Chang, Weijia Zheng, Jeongmin Choi, Hee Yi, Jaehan Shim, A Abd M Elaty, Hochul ShinAbstract:Abstract In this study, a simple analytical approach has been developed and validated for the determination of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle, beef, milk, egg, shrimp, flatfish, and eel using liquid chromatography-tandem mass spectrometry (LC–MS/MS). A 0.1% solution of acetic acid in acetonitrile combined with n-hexane was used for deproteinization and defatting of all tested matrices and the target drugs were well separated on a Waters Xbridge™ C18 analytical column using a mobile phase consisting of 0.1% acetic acid (A) and 0.1% solution of acetic acid in methanol (B). The linearity estimated from six-point matrix-matched calibrations was good, with coefficients of determination ≥0.9873. The limits of quantification (LOQs) for bupivacaine hydrochloride and Isoflupredone Acetate were 1 and 2 ng g−1, respectively. Recovery percentages in the ranges of 72.51–112.39% (bupivacaine hydrochloride) and 72.58–114.56% (Isoflupredone Acetate) were obtained from three different fortification concentrations with relative standard deviations (RSDs) of
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quantification of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle beef milk egg shrimp flatfish and eel using a simplified extraction method coupled with liquid chromatography triple quadrupole tandem mass spectrometry
Journal of Chromatography A, 2017Co-Authors: Jina Park, N A Afifi, Byungjoon Chang, Weijia Zheng, Jeongmin Choi, Hee Yi, Jaehan Shim, A Abd M Elaty, Hochul ShinAbstract:In this study, a simple analytical approach has been developed and validated for the determination of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle, beef, milk, egg, shrimp, flatfish, and eel using liquid chromatography-tandem mass spectrometry (LC–MS/MS). A 0.1% solution of acetic acid in acetonitrile combined with n-hexane was used for deproteinization and defatting of all tested matrices and the target drugs were well separated on a Waters Xbridge™ C18 analytical column using a mobile phase consisting of 0.1% acetic acid (A) and 0.1% solution of acetic acid in methanol (B). The linearity estimated from six-point matrix-matched calibrations was good, with coefficients of determination ≥0.9873. The limits of quantification (LOQs) for bupivacaine hydrochloride and Isoflupredone Acetate were 1 and 2ngg⁻¹, respectively. Recovery percentages in the ranges of 72.51–112.39% (bupivacaine hydrochloride) and 72.58–114.56% (Isoflupredone Acetate) were obtained from three different fortification concentrations with relative standard deviations (RSDs) of <15.14%. All samples for the experimental work and method application were collected from the local markets in Seoul, Republic of Korea, and none of them tested positive for the target drugs. In conclusion, a simple method using a 0.1% solution of acetic acid in acetonitrile and n-hexane followed by LC–MS/MS could effectively extract bupivacaine hydrochloride and Isoflupredone Acetate from porcine muscle, beef, milk, egg, shrimp, flatfish, and eel samples.
Jina Park - One of the best experts on this subject based on the ideXlab platform.
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quantification of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle beef milk egg shrimp flatfish and eel using a simplified extraction method coupled with liquid chromatography triple quadrupole tandem mass spectrometry
Journal of Chromatography B, 2017Co-Authors: Jina Park, N A Afifi, Byungjoon Chang, Weijia Zheng, Jeongmin Choi, Hee Yi, Jaehan Shim, A Abd M Elaty, Hochul ShinAbstract:Abstract In this study, a simple analytical approach has been developed and validated for the determination of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle, beef, milk, egg, shrimp, flatfish, and eel using liquid chromatography-tandem mass spectrometry (LC–MS/MS). A 0.1% solution of acetic acid in acetonitrile combined with n-hexane was used for deproteinization and defatting of all tested matrices and the target drugs were well separated on a Waters Xbridge™ C18 analytical column using a mobile phase consisting of 0.1% acetic acid (A) and 0.1% solution of acetic acid in methanol (B). The linearity estimated from six-point matrix-matched calibrations was good, with coefficients of determination ≥0.9873. The limits of quantification (LOQs) for bupivacaine hydrochloride and Isoflupredone Acetate were 1 and 2 ng g−1, respectively. Recovery percentages in the ranges of 72.51–112.39% (bupivacaine hydrochloride) and 72.58–114.56% (Isoflupredone Acetate) were obtained from three different fortification concentrations with relative standard deviations (RSDs) of
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quantification of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle beef milk egg shrimp flatfish and eel using a simplified extraction method coupled with liquid chromatography triple quadrupole tandem mass spectrometry
Journal of Chromatography A, 2017Co-Authors: Jina Park, N A Afifi, Byungjoon Chang, Weijia Zheng, Jeongmin Choi, Hee Yi, Jaehan Shim, A Abd M Elaty, Hochul ShinAbstract:In this study, a simple analytical approach has been developed and validated for the determination of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle, beef, milk, egg, shrimp, flatfish, and eel using liquid chromatography-tandem mass spectrometry (LC–MS/MS). A 0.1% solution of acetic acid in acetonitrile combined with n-hexane was used for deproteinization and defatting of all tested matrices and the target drugs were well separated on a Waters Xbridge™ C18 analytical column using a mobile phase consisting of 0.1% acetic acid (A) and 0.1% solution of acetic acid in methanol (B). The linearity estimated from six-point matrix-matched calibrations was good, with coefficients of determination ≥0.9873. The limits of quantification (LOQs) for bupivacaine hydrochloride and Isoflupredone Acetate were 1 and 2ngg⁻¹, respectively. Recovery percentages in the ranges of 72.51–112.39% (bupivacaine hydrochloride) and 72.58–114.56% (Isoflupredone Acetate) were obtained from three different fortification concentrations with relative standard deviations (RSDs) of <15.14%. All samples for the experimental work and method application were collected from the local markets in Seoul, Republic of Korea, and none of them tested positive for the target drugs. In conclusion, a simple method using a 0.1% solution of acetic acid in acetonitrile and n-hexane followed by LC–MS/MS could effectively extract bupivacaine hydrochloride and Isoflupredone Acetate from porcine muscle, beef, milk, egg, shrimp, flatfish, and eel samples.
N A Afifi - One of the best experts on this subject based on the ideXlab platform.
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quantification of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle beef milk egg shrimp flatfish and eel using a simplified extraction method coupled with liquid chromatography triple quadrupole tandem mass spectrometry
Journal of Chromatography B, 2017Co-Authors: Jina Park, N A Afifi, Byungjoon Chang, Weijia Zheng, Jeongmin Choi, Hee Yi, Jaehan Shim, A Abd M Elaty, Hochul ShinAbstract:Abstract In this study, a simple analytical approach has been developed and validated for the determination of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle, beef, milk, egg, shrimp, flatfish, and eel using liquid chromatography-tandem mass spectrometry (LC–MS/MS). A 0.1% solution of acetic acid in acetonitrile combined with n-hexane was used for deproteinization and defatting of all tested matrices and the target drugs were well separated on a Waters Xbridge™ C18 analytical column using a mobile phase consisting of 0.1% acetic acid (A) and 0.1% solution of acetic acid in methanol (B). The linearity estimated from six-point matrix-matched calibrations was good, with coefficients of determination ≥0.9873. The limits of quantification (LOQs) for bupivacaine hydrochloride and Isoflupredone Acetate were 1 and 2 ng g−1, respectively. Recovery percentages in the ranges of 72.51–112.39% (bupivacaine hydrochloride) and 72.58–114.56% (Isoflupredone Acetate) were obtained from three different fortification concentrations with relative standard deviations (RSDs) of
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quantification of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle beef milk egg shrimp flatfish and eel using a simplified extraction method coupled with liquid chromatography triple quadrupole tandem mass spectrometry
Journal of Chromatography A, 2017Co-Authors: Jina Park, N A Afifi, Byungjoon Chang, Weijia Zheng, Jeongmin Choi, Hee Yi, Jaehan Shim, A Abd M Elaty, Hochul ShinAbstract:In this study, a simple analytical approach has been developed and validated for the determination of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle, beef, milk, egg, shrimp, flatfish, and eel using liquid chromatography-tandem mass spectrometry (LC–MS/MS). A 0.1% solution of acetic acid in acetonitrile combined with n-hexane was used for deproteinization and defatting of all tested matrices and the target drugs were well separated on a Waters Xbridge™ C18 analytical column using a mobile phase consisting of 0.1% acetic acid (A) and 0.1% solution of acetic acid in methanol (B). The linearity estimated from six-point matrix-matched calibrations was good, with coefficients of determination ≥0.9873. The limits of quantification (LOQs) for bupivacaine hydrochloride and Isoflupredone Acetate were 1 and 2ngg⁻¹, respectively. Recovery percentages in the ranges of 72.51–112.39% (bupivacaine hydrochloride) and 72.58–114.56% (Isoflupredone Acetate) were obtained from three different fortification concentrations with relative standard deviations (RSDs) of <15.14%. All samples for the experimental work and method application were collected from the local markets in Seoul, Republic of Korea, and none of them tested positive for the target drugs. In conclusion, a simple method using a 0.1% solution of acetic acid in acetonitrile and n-hexane followed by LC–MS/MS could effectively extract bupivacaine hydrochloride and Isoflupredone Acetate from porcine muscle, beef, milk, egg, shrimp, flatfish, and eel samples.
Byungjoon Chang - One of the best experts on this subject based on the ideXlab platform.
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quantification of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle beef milk egg shrimp flatfish and eel using a simplified extraction method coupled with liquid chromatography triple quadrupole tandem mass spectrometry
Journal of Chromatography B, 2017Co-Authors: Jina Park, N A Afifi, Byungjoon Chang, Weijia Zheng, Jeongmin Choi, Hee Yi, Jaehan Shim, A Abd M Elaty, Hochul ShinAbstract:Abstract In this study, a simple analytical approach has been developed and validated for the determination of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle, beef, milk, egg, shrimp, flatfish, and eel using liquid chromatography-tandem mass spectrometry (LC–MS/MS). A 0.1% solution of acetic acid in acetonitrile combined with n-hexane was used for deproteinization and defatting of all tested matrices and the target drugs were well separated on a Waters Xbridge™ C18 analytical column using a mobile phase consisting of 0.1% acetic acid (A) and 0.1% solution of acetic acid in methanol (B). The linearity estimated from six-point matrix-matched calibrations was good, with coefficients of determination ≥0.9873. The limits of quantification (LOQs) for bupivacaine hydrochloride and Isoflupredone Acetate were 1 and 2 ng g−1, respectively. Recovery percentages in the ranges of 72.51–112.39% (bupivacaine hydrochloride) and 72.58–114.56% (Isoflupredone Acetate) were obtained from three different fortification concentrations with relative standard deviations (RSDs) of
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quantification of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle beef milk egg shrimp flatfish and eel using a simplified extraction method coupled with liquid chromatography triple quadrupole tandem mass spectrometry
Journal of Chromatography A, 2017Co-Authors: Jina Park, N A Afifi, Byungjoon Chang, Weijia Zheng, Jeongmin Choi, Hee Yi, Jaehan Shim, A Abd M Elaty, Hochul ShinAbstract:In this study, a simple analytical approach has been developed and validated for the determination of bupivacaine hydrochloride and Isoflupredone Acetate residues in porcine muscle, beef, milk, egg, shrimp, flatfish, and eel using liquid chromatography-tandem mass spectrometry (LC–MS/MS). A 0.1% solution of acetic acid in acetonitrile combined with n-hexane was used for deproteinization and defatting of all tested matrices and the target drugs were well separated on a Waters Xbridge™ C18 analytical column using a mobile phase consisting of 0.1% acetic acid (A) and 0.1% solution of acetic acid in methanol (B). The linearity estimated from six-point matrix-matched calibrations was good, with coefficients of determination ≥0.9873. The limits of quantification (LOQs) for bupivacaine hydrochloride and Isoflupredone Acetate were 1 and 2ngg⁻¹, respectively. Recovery percentages in the ranges of 72.51–112.39% (bupivacaine hydrochloride) and 72.58–114.56% (Isoflupredone Acetate) were obtained from three different fortification concentrations with relative standard deviations (RSDs) of <15.14%. All samples for the experimental work and method application were collected from the local markets in Seoul, Republic of Korea, and none of them tested positive for the target drugs. In conclusion, a simple method using a 0.1% solution of acetic acid in acetonitrile and n-hexane followed by LC–MS/MS could effectively extract bupivacaine hydrochloride and Isoflupredone Acetate from porcine muscle, beef, milk, egg, shrimp, flatfish, and eel samples.
