The Experts below are selected from a list of 9 Experts worldwide ranked by ideXlab platform

M. P. Copper - One of the best experts on this subject based on the ideXlab platform.

  • Drug-induced sleep endoscopy while administering CPAP therapy in patients with CPAP failure
    Sleep and Breathing, 2020
    Co-Authors: E. Dieleman, C. C. A. F. M. Veugen, J. A. Hardeman, M. P. Copper
    Abstract:

    Study objectives To study the pattern of upper airway collapse in patients with CPAP failure by performing DISE while administering CPAP therapy and to determine the reason for CPAP failure accordingly. Methods This observational retrospective study comprised 30 patients diagnosed with OSA and CPAP failure, who underwent DISE while administering CPAP therapy. During DISE, the upper airway was assessed with and without CPAP therapy using the VOTE classification. Additionally, a jaw thrust Maneuver was performed, in order to mimic the effect of an additional mandibular advancement device (MAD) in combination with CPAP therapy. Consequently, the outcome of DISE was translated into a clinically relevant categorization. Results Eleven patients (37%) had a persistent anteroposterior (AP) collapse, including a collapse at velum, tongue base, or epiglottis level and multilevel collapse. Eight patients (27%) had a floppy epiglottis. Five patients (17%) had a persistent complete concentric collapse (CCC) and three patients had a persistent laryngeal collapse (10%). In three patients (10%), no airway collapse was found after CPAP administration. Conclusions Based on the results of the reported study, in most cases, the potential cause of CPAP failure can be determined by this new diagnostic method. Consequently, suggestions can be made for additional therapy.

E. Dieleman - One of the best experts on this subject based on the ideXlab platform.

  • Drug-induced sleep endoscopy while administering CPAP therapy in patients with CPAP failure
    Sleep and Breathing, 2020
    Co-Authors: E. Dieleman, C. C. A. F. M. Veugen, J. A. Hardeman, M. P. Copper
    Abstract:

    Study objectives To study the pattern of upper airway collapse in patients with CPAP failure by performing DISE while administering CPAP therapy and to determine the reason for CPAP failure accordingly. Methods This observational retrospective study comprised 30 patients diagnosed with OSA and CPAP failure, who underwent DISE while administering CPAP therapy. During DISE, the upper airway was assessed with and without CPAP therapy using the VOTE classification. Additionally, a jaw thrust Maneuver was performed, in order to mimic the effect of an additional mandibular advancement device (MAD) in combination with CPAP therapy. Consequently, the outcome of DISE was translated into a clinically relevant categorization. Results Eleven patients (37%) had a persistent anteroposterior (AP) collapse, including a collapse at velum, tongue base, or epiglottis level and multilevel collapse. Eight patients (27%) had a floppy epiglottis. Five patients (17%) had a persistent complete concentric collapse (CCC) and three patients had a persistent laryngeal collapse (10%). In three patients (10%), no airway collapse was found after CPAP administration. Conclusions Based on the results of the reported study, in most cases, the potential cause of CPAP failure can be determined by this new diagnostic method. Consequently, suggestions can be made for additional therapy.

C. C. A. F. M. Veugen - One of the best experts on this subject based on the ideXlab platform.

  • Drug-induced sleep endoscopy while administering CPAP therapy in patients with CPAP failure
    Sleep and Breathing, 2020
    Co-Authors: E. Dieleman, C. C. A. F. M. Veugen, J. A. Hardeman, M. P. Copper
    Abstract:

    Study objectives To study the pattern of upper airway collapse in patients with CPAP failure by performing DISE while administering CPAP therapy and to determine the reason for CPAP failure accordingly. Methods This observational retrospective study comprised 30 patients diagnosed with OSA and CPAP failure, who underwent DISE while administering CPAP therapy. During DISE, the upper airway was assessed with and without CPAP therapy using the VOTE classification. Additionally, a jaw thrust Maneuver was performed, in order to mimic the effect of an additional mandibular advancement device (MAD) in combination with CPAP therapy. Consequently, the outcome of DISE was translated into a clinically relevant categorization. Results Eleven patients (37%) had a persistent anteroposterior (AP) collapse, including a collapse at velum, tongue base, or epiglottis level and multilevel collapse. Eight patients (27%) had a floppy epiglottis. Five patients (17%) had a persistent complete concentric collapse (CCC) and three patients had a persistent laryngeal collapse (10%). In three patients (10%), no airway collapse was found after CPAP administration. Conclusions Based on the results of the reported study, in most cases, the potential cause of CPAP failure can be determined by this new diagnostic method. Consequently, suggestions can be made for additional therapy.

J. A. Hardeman - One of the best experts on this subject based on the ideXlab platform.

  • Drug-induced sleep endoscopy while administering CPAP therapy in patients with CPAP failure
    Sleep and Breathing, 2020
    Co-Authors: E. Dieleman, C. C. A. F. M. Veugen, J. A. Hardeman, M. P. Copper
    Abstract:

    Study objectives To study the pattern of upper airway collapse in patients with CPAP failure by performing DISE while administering CPAP therapy and to determine the reason for CPAP failure accordingly. Methods This observational retrospective study comprised 30 patients diagnosed with OSA and CPAP failure, who underwent DISE while administering CPAP therapy. During DISE, the upper airway was assessed with and without CPAP therapy using the VOTE classification. Additionally, a jaw thrust Maneuver was performed, in order to mimic the effect of an additional mandibular advancement device (MAD) in combination with CPAP therapy. Consequently, the outcome of DISE was translated into a clinically relevant categorization. Results Eleven patients (37%) had a persistent anteroposterior (AP) collapse, including a collapse at velum, tongue base, or epiglottis level and multilevel collapse. Eight patients (27%) had a floppy epiglottis. Five patients (17%) had a persistent complete concentric collapse (CCC) and three patients had a persistent laryngeal collapse (10%). In three patients (10%), no airway collapse was found after CPAP administration. Conclusions Based on the results of the reported study, in most cases, the potential cause of CPAP failure can be determined by this new diagnostic method. Consequently, suggestions can be made for additional therapy.

Mansour Mohamed - One of the best experts on this subject based on the ideXlab platform.

  • Effect of fiberoptic intubation on myocardial ischemia and hormonal stress response in diabetics with ischemic heart disease
    Production and hosting by Elsevier B.V., 2014
    Co-Authors: Mohamed, Nashwa Nabil, Hasanein Reham, Rashwan Doaa, Mansour Mohamed
    Abstract:

    AbstractBackgroundDiabetic patients with ischemic heart disease can greatly benefit from decreasing the stress response to intubation with its metabolic sequelae. The use of fiberoptic bronchoscopy will eliminate the response to direct laryngoscopy while lubrication of ETT with lidocaine gel 2% will decrease the response to endotracheal intubation. This study was conducted to compare the stress response hormones (glucose, cortisol and c-peptide) and the hemodynamic responses to intubation between direct laryngoscopy and fiberoptic bronchoscopy in diabetic ischemic patients.Patients and methodsForty-four adult diabetic patients with ischemic heart disease, ASA II, with a blood glucose level between 120 and 180mg/dL, requiring orotracheal intubation under general anesthesia were divided into 2 equal groups. The laryngoscopic group (n=22) and the fiberoptic group (n=22). Ovassapian airway was used to facilitate fiberoptic intubation with avoidance of jaw thrust Maneuver. Blood glucose, cortisol and c-peptide were recorded before induction and 10min after intubation and compared between both groups. The hemodynamic parameters were recorded and compared between both groups. Automated ST segment monitoring was used to detect ischemia.ResultsThere was statistically significant increase in HR, SBP and DBP in laryngoscopic group than in fiberoptic group. However, the incidence of ECG ST-segment changes was comparable with no statistically significant difference between groups. There were no statistically significant differences regarding glucose, cortisol and c-peptide levels between the study groups pre and post-induction. The intubation time in the fiberoptic group showed a statistically significant increase in comparison with the laryngoscope group (39±12.04 vs. 29.3±8.54s; P