Statistically Significant Difference

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Berit Calissendorff - One of the best experts on this subject based on the ideXlab platform.

  • factors influencing the formation of posterior capsular opacities after extracapsular cataract extraction with posterior chamber lens implant
    Acta Ophthalmologica, 2009
    Co-Authors: Agneta K Westling, Berit Calissendorff
    Abstract:

    This study was designed to determine whether different factors could influence the formation of posterior capsular opacities. The study group comprised 271 patients who had undergone an extracapsular cataract extraction with implantation of a posterior chamber lens either with or without laser ridge. Between 12 and 25 months after surgery, a Statistically Significant Difference was found with a lower rate of secondary cataract in the laser ridge group, but with respect to advanced secondary cataract, i.e. eyes which needed YAG capsulotomy, no Statistically Significant Difference was found (P-value 0.99). No association was found between age or sex of patients, different surgeons or complications during or after surgery and the risk of getting a secondary cataract.

Ali Guermazi - One of the best experts on this subject based on the ideXlab platform.

Iqbal Ike K Ahmed - One of the best experts on this subject based on the ideXlab platform.

  • efficacy and safety of femtosecond laser assisted cataract surgery compared with manual cataract surgery a meta analysis of 14 567 eyes
    Ophthalmology, 2016
    Co-Authors: Marko Popovic, Xavier Camposmoller, Matthew B Schlenker, Iqbal Ike K Ahmed
    Abstract:

    Topic To investigate the efficacy and safety of femtosecond laser-assisted cataract surgery (FLACS) relative to manual cataract surgery (MCS). Clinical Relevance It is unclear whether FLACS is more efficacious and safe relative to MCS. Methods A literature search of MEDLINE, EMBASE, and Scopus from 2007 to March 2016 was conducted. Studies containing both FLACS and MCS arms that reported on relevant efficacy and/or safety parameters were included. Weighted mean Differences (WMDs) and risk ratios (RRs) with 95% confidence intervals (CIs) were calculated. Results From 2802 screened articles, 14 567 eyes from 15 randomized controlled trials and 22 observational cohort studies were included. For primary visual and refractive outcomes, no Statistically Significant Difference was detected between FLACS and MCS in uncorrected distance visual acuity (WMD, −0.02; 95% CI, −0.04 to 0.01; P  = 0.19), corrected distance visual acuity (WMD, −0.01; 95% CI, −0.02 to 0.01; P  = 0.26), and mean absolute error (WMD, −0.02; 95% CI, −0.07 to 0.04; P  = 0.57). In terms of secondary surgical end points, there was a Statistically Significant Difference in favor of FLACS over MCS for effective phacoemulsification time (WMD, −3.03; 95% CI, −3.80 to −2.25; P P P  = 0.02), and corneal endothelial cell reduction (WMD, −55.43; 95% CI, −95.18 to −15.69; P  = 0.006). There was no Statistically Significant Difference between FLACS and MCS for total surgery time (WMD, 1.25; 95% CI, −0.08 to 2.59; P  = 0.07), capsulotomy circularity using a second formula (WMD, 0.05; 95% CI, −0.01 to 0.12; P  = 0.10), and corneal endothelial cell count (WMD, 73.39; 95% CI, −6.28 to 153.07; P  = 0.07). As well, there was a Significantly higher concentration of prostaglandins after FLACS relative to MCS (WMD, 198.34; 95% CI, 129.99–266.69; P P  = 0.16); however, posterior capsular tears were Significantly more common in FLACS versus MCS (RR, 3.73; 95% CI, 1.50–9.25; P  = 0.005). Conclusions There were no Statistically Significant Differences detected between FLACS and MCS in terms of patient-important visual and refractive outcomes and overall complications. Although FLACS did show a Statistically Significant Difference for several secondary surgical outcomes, it was associated with higher prostaglandin concentrations and higher rates of posterior capsular tears.

Agneta K Westling - One of the best experts on this subject based on the ideXlab platform.

  • factors influencing the formation of posterior capsular opacities after extracapsular cataract extraction with posterior chamber lens implant
    Acta Ophthalmologica, 2009
    Co-Authors: Agneta K Westling, Berit Calissendorff
    Abstract:

    This study was designed to determine whether different factors could influence the formation of posterior capsular opacities. The study group comprised 271 patients who had undergone an extracapsular cataract extraction with implantation of a posterior chamber lens either with or without laser ridge. Between 12 and 25 months after surgery, a Statistically Significant Difference was found with a lower rate of secondary cataract in the laser ridge group, but with respect to advanced secondary cataract, i.e. eyes which needed YAG capsulotomy, no Statistically Significant Difference was found (P-value 0.99). No association was found between age or sex of patients, different surgeons or complications during or after surgery and the risk of getting a secondary cataract.

Fang Liu - One of the best experts on this subject based on the ideXlab platform.