The Experts below are selected from a list of 15 Experts worldwide ranked by ideXlab platform
Thilaga Rani K Kuppusamy.k - One of the best experts on this subject based on the ideXlab platform.
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Kimuras Disease a case report
University Journal of Pre and Paraclinical Sciences, 2016Co-Authors: Thilaga Rani K Kuppusamy.kAbstract:Kimuras Disease is a rare chronic inflammatory Disease that presents as a subcutaneous mass in the head and neck region often associated with regional cervical lymphadenopathy. We report a case of Kimuras Disease in a 14yr male. who presented with bilateral cervical lymphadenopathy. The diagnosis was based on characteristic histopathological findings in correlation with peripheral eosinophilia and elevated serum Immunoglobulin E levels. The histopathological differential diagnoses have also been discussed.
Vinay Babu Venkataramana - One of the best experts on this subject based on the ideXlab platform.
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Kimuras Disease-A CASE REPORT
University Journal of Medicine and Medical Specialities, 2016Co-Authors: Vinay Babu VenkataramanaAbstract:A 24 year old female patient presented with multiple, painless swellings in the neck and axilla for 6 months. Routine investigations were inconclusive except elevated eosinophilic count. Clinically it appeared to be lymphoma. Fine needle aspiration cytology was reported to be a reactive hyperplasia while excision biopsy of the cervical lymph node revealed the diagnosis as Kimuras Disease. This disorder should be suspected when painless cervical adenopathy, hypereosinophilia and hyper-IgE is present, particularly in male Asian patients. Keyword :Kimuras Disease, lymphadenopathy, eosinophilia and hyperimmunoglobulinaemia. Introduction Kimura’s Disease (KD) is an allergic inflammatory disorder of unknown cause characterized by swelling in the head and neck region with the involvement of subcutaneous tissue, major salivary glands and lymph nodes. It is a benign condition but may be mistaken for malignant Disease. Kimura’s Disease is often accompanied by lymphadenopathy, eosinophilia and elevated IgE concentration. Renal involvement is its only systemic manifestation. Various treatment modalities have been tried including oral and intralesional steroid, surgical excision, cryotherapy, laser therapy and radiotherapy. However, the Disease is usually persistent and difficult to eradicate.
M G Roccia - One of the best experts on this subject based on the ideXlab platform.
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uncommon clinical presentation of Kimuras Disease as bilateral retroauricular masses in a young malian male successful surgical approach
Journal of Biological Regulators and Homeostatic Agents, 2016Co-Authors: Fausto Fama, A Sindoni, Georgi Tchernev, A A Chokoeva, Uwe Wollina, Torello Lotti, G K Maximov, James W Patterson, Massimo Fioranelli, M G RocciaAbstract:We present a case of a 27 year-old Malian male referred to our hospital for two large, painless retroauricolar masses that had appeared two years earlier. Bilateral cervical painless lymphadenopathy was present at physical examination, without any other systemic symptoms. His history was relevant for bilateral Kimuras Disease lesions resected 5 years earlier in the same locations. Lymphocytosis and a mild hypereosinophilia were found in routine blood tests, together with increased total IgE levels. After surgery, histology showed lymphoid infiltrates with reactive prominent germinal centres containing eosinophils, suggesting relapse of Kimuras Disease, in the context of nonencapsulated fibrous proliferation with discontinuous collagen fibers, consistent with keloid. Three months after removal of retroauricular masses, abnormal laboratory findings reverted to normal. To the best our knowledge, this is the first case in literature of bilateral keloid lesions developed after surgery for Kimura Disease and harbouring its histopathologic features. Clinicians should be aware of these unusual reactive phenomena and their possible simulators.
Fausto Fama - One of the best experts on this subject based on the ideXlab platform.
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uncommon clinical presentation of Kimuras Disease as bilateral retroauricular masses in a young malian male successful surgical approach
Journal of Biological Regulators and Homeostatic Agents, 2016Co-Authors: Fausto Fama, A Sindoni, Georgi Tchernev, A A Chokoeva, Uwe Wollina, Torello Lotti, G K Maximov, James W Patterson, Massimo Fioranelli, M G RocciaAbstract:We present a case of a 27 year-old Malian male referred to our hospital for two large, painless retroauricolar masses that had appeared two years earlier. Bilateral cervical painless lymphadenopathy was present at physical examination, without any other systemic symptoms. His history was relevant for bilateral Kimuras Disease lesions resected 5 years earlier in the same locations. Lymphocytosis and a mild hypereosinophilia were found in routine blood tests, together with increased total IgE levels. After surgery, histology showed lymphoid infiltrates with reactive prominent germinal centres containing eosinophils, suggesting relapse of Kimuras Disease, in the context of nonencapsulated fibrous proliferation with discontinuous collagen fibers, consistent with keloid. Three months after removal of retroauricular masses, abnormal laboratory findings reverted to normal. To the best our knowledge, this is the first case in literature of bilateral keloid lesions developed after surgery for Kimura Disease and harbouring its histopathologic features. Clinicians should be aware of these unusual reactive phenomena and their possible simulators.
Georgi Tchernev - One of the best experts on this subject based on the ideXlab platform.
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uncommon clinical presentation of Kimuras Disease as bilateral retroauricular masses in a young malian male successful surgical approach
Journal of Biological Regulators and Homeostatic Agents, 2016Co-Authors: Fausto Fama, A Sindoni, Georgi Tchernev, A A Chokoeva, Uwe Wollina, Torello Lotti, G K Maximov, James W Patterson, Massimo Fioranelli, M G RocciaAbstract:We present a case of a 27 year-old Malian male referred to our hospital for two large, painless retroauricolar masses that had appeared two years earlier. Bilateral cervical painless lymphadenopathy was present at physical examination, without any other systemic symptoms. His history was relevant for bilateral Kimuras Disease lesions resected 5 years earlier in the same locations. Lymphocytosis and a mild hypereosinophilia were found in routine blood tests, together with increased total IgE levels. After surgery, histology showed lymphoid infiltrates with reactive prominent germinal centres containing eosinophils, suggesting relapse of Kimuras Disease, in the context of nonencapsulated fibrous proliferation with discontinuous collagen fibers, consistent with keloid. Three months after removal of retroauricular masses, abnormal laboratory findings reverted to normal. To the best our knowledge, this is the first case in literature of bilateral keloid lesions developed after surgery for Kimura Disease and harbouring its histopathologic features. Clinicians should be aware of these unusual reactive phenomena and their possible simulators.
