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Ewa M Roos - One of the best experts on this subject based on the ideXlab platform.

  • item selection for 12 item short forms of the Knee Injury and osteoarthritis outcome score koos 12 and hip disability and osteoarthritis outcome score hoos 12
    Osteoarthritis and Cartilage, 2019
    Co-Authors: Barbara Gandek, Ewa M Roos, Patricia D Franklin, John E Ware
    Abstract:

    Summary Objective To develop 12-item short forms (KOOS-12, HOOS-12) of the 42-item Knee Injury and Osteoarthritis Outcome Score (KOOS) and 40-item Hip disability and Osteoarthritis Outcome Score (HOOS) that represent the full-length instruments sufficiently to provide joint-specific pain, function and quality of life (QOL) domain and summary joint impact scores. This paper describes KOOS-12 and HOOS-12 item selection. Subsequent papers will examine KOOS-12 and HOOS-12 reliability, validity and responsiveness. Design Items were selected based on qualitative information from patients, clinicians and KOOS/HOOS translators and analysis of data from 1,395 Knee osteoarthritis (OA) and 1,281 hip OA patients from the FORCE-TJR cohort who completed KOOS or HOOS before and after total joint replacement (TJR). Item response theory models and computerized adaptive test (CAT) simulations were used to identify items that best measured patients' levels of pain and function pre- and post-TJR. KOOS-12/HOOS-12 items were selected based on content, coverage of a wide measurement range, high item information, item usage in CAT simulations, scale-level properties (reliability, validity, responsiveness), and qualitative information. Results KOOS-12 and HOOS-12 each included a pain frequency item and three items measuring pain during increasingly difficult activities (sitting/lying, walking, up/down stairs); function items about standing, rising from sitting, getting in/out of a car, and twisting/pivoting (KOOS-12) or walking on an uneven surface (HOOS-12); and the original 4-item QOL scale. Conclusions This study demonstrated the benefits of examining patient-reported outcome measures using modern psychometric methods, to create short forms with diverse content that provide domain-specific and summary joint impact scores.

  • meaningful change scores in the Knee Injury and osteoarthritis outcome score in patients undergoing anterior cruciate ligament reconstruction
    American Journal of Sports Medicine, 2018
    Co-Authors: Caroline B Terwee, Lina Holm Ingelsrud, Berend Terluin, Larspetter Granan, Lars Engebretsen, Kathryn Mills, Ewa M Roos
    Abstract:

    Background:Meaningful change scores in the Knee Injury and Osteoarthritis Outcome Score (KOOS) in patients undergoing anterior cruciate ligament (ACL) reconstruction have not yet been established.Purpose:To define the minimal important change (MIC) for the KOOS after ACL reconstruction.Study Design:Cohort study (diagnosis); Level of evidence, 2.Methods:KOOS and anchor questions with 7-point scales ranging from “better, an important improvement” to “worse, an important worsening” were completed postoperatively by randomly chosen participants from the Norwegian Knee Ligament Registry. Presurgery KOOS scores were retrieved from the registry. The MIC for improvement was calculated with anchor-based approaches using the predictive modeling method adjusted for the proportion of improved patients, the mean change method, and the receiver operating characteristic (ROC) method.Results:Complete data for at least one of the KOOS subscales were obtained from 542 (45.3%) participants. Predictive modeling MIC values we...

  • Knee Injury and osteoarthritis outcome score koos systematic review and meta analysis of measurement properties
    Osteoarthritis and Cartilage, 2016
    Co-Authors: Natalie J. Collins, Caroline B Terwee, C A C Prinsen, Robin Christensen, E M Bartels, Ewa M Roos
    Abstract:

    Summary Objective To conduct a systematic review and meta-analysis to synthesize evidence regarding measurement properties of the Knee Injury and Osteoarthritis Outcome Score (KOOS). Design A comprehensive literature search identified 37 eligible papers evaluating KOOS measurement properties in participants with Knee injuries and/or osteoarthritis (OA). Methodological quality was evaluated using the COSMIN checklist. Where possible, meta-analysis of extracted data was conducted for all studies and stratified by age and Knee condition; otherwise narrative synthesis was performed. Results KOOS has adequate internal consistency, test-retest reliability and construct validity in young and old adults with Knee injuries and/or OA. The ADL subscale has better content validity for older patients and Sport/Rec for younger patients with Knee injuries, while the Pain subscale is more relevant for painful Knee conditions. The five-factor structure of the original KOOS is unclear. There is some evidence that the KOOS subscales demonstrate sufficient unidimensionality, but this requires confirmation. Although measurement error requires further evaluation, the minimal detectable change for KOOS subscales ranges from 14.3 to 19.6 for younger individuals, and ≥20 for older individuals. Evidence of responsiveness comes from larger effect sizes following surgical (especially total Knee replacement) than non-surgical interventions. Conclusions KOOS demonstrates adequate content validity, internal consistency, test-retest reliability, construct validity and responsiveness for age- and condition-relevant subscales. Structural validity, cross-cultural validity and measurement error require further evaluation, as well as construct validity of KOOS Physical function Short form. Suggested order of subscales for different Knee conditions can be applied in hierarchical testing of endpoints in clinical trials. Systematic review registration: PROSPERO (CRD42011001603).

  • examining the minimal important difference of patient reported outcome measures for individuals with Knee osteoarthritis a model using the Knee Injury and osteoarthritis outcome score
    The Journal of Rheumatology, 2016
    Co-Authors: Kathryn Mills, Ewa M Roos, Justine M Naylor, Jillian P Eyles, David J Hunter
    Abstract:

    Objective. To examine the influence of different analytical methods, baseline covariates, followup periods, and anchor questions when establishing a minimal important difference (MID) for individuals with Knee osteoarthritis (OA). Second, to propose MID for improving and worsening on the Knee Injury and Osteoarthritis Outcome Score (KOOS). Methods. Retrospective analysis of prospectively collected data from 272 patients with Knee OA undergoing a multidisciplinary nonsurgical management strategy. The magnitude and rate of change as well as the influence of baseline covariates were examined for 5 KOOS subscales over 52 weeks. The MID for improving and worsening were investigated using 4 anchor-based methods. Results. Waitlisted for joint replacement and exhibiting unilateral/bilateral symptoms influenced change in KOOS over time. Generally, low correlations between anchors and KOOS change scores limited calculations of MID; thus, they were only proposed for the pain, activities of daily living, and quality of life subscales. The method used to calculate the MID influenced the cutpoint; however, the type of anchor question only influenced the MID when analyzed with a particular mean change method. Depending on patient and clinical characteristics, the subscale, and the analytical approach used, the MID for KOOS improvement ranged from an absolute change of −1.5 to 20.6 points and worsening ranged from −19.17 to 8.5 points. Conclusion. MID vary with patient and clinical characteristics, KOOS subscale, and analytical approach. Provided the anchor question is relevant to the patient-reported outcome and baseline status is considered, the anchor does not appear to influence the MID for improvement or worsening when using some anchor-based methods.

  • cross cultural translation and measurement properties of the polish version of the Knee Injury and osteoarthritis outcome score koos following anterior cruciate ligament reconstruction
    Health and Quality of Life Outcomes, 2013
    Co-Authors: Przemyslaw T Paradowski, Dariusz Witonski, Rafal Keska, Ewa M Roos
    Abstract:

    Background: Knee Injury and Osteoarthritis Outcome Score (KOOS) is available in over 30 languages and a commonly used Patient-Reported Outcome (PRO) for assessment of treatment effects following Knee surgery. The aim of the study was to report the linguistic translational process and evaluate the psychometric properties of the Polish version of the KOOS questionnaire. Methods: We translated and culturally adapted the KOOS according to current guidelines for use in Poland. Patients who had undergone anterior cruciate ligament reconstruction (ACLR) completed the KOOS and Short Form 36 Health Survey (SF-36). We evaluated floor/ceiling effects, reliability (using Cronbach’s alpha, intraclass correlation coefficients (ICC) and measurement error), convergent and divergent construct validity (using four ap riori stated hypotheses) and responsiveness (using data obtained prior to and one year after ACLR and described by both effect size (ES) and standardized response mean (SRM)). Results: The clinical study population consisted of 72 subjects (mean age 29.8, 28% women). We did not observe floor effects in any KOOS subscales neither pre- nor postoperatively. As expected, ceiling effects were found postoperatively for the subscales Pain and ADL in this cohort assessed on average 1.3 year after surgery as more than 15% reported no pain or limitations in daily activities. The Cronbach’s alpha was above 0.9 for all subscales indicating excellent internal consistency. The test-retest reliability of all KOOS subscales at one-year postoperatively was excellent with ICCs exceeding 0.86 for all subscales. The minimal detectable change on group level ranged from 1.3 to 2.4, and on an individual level from 10.9 to 20.2. Responsiveness was demonstrated since the expected pattern of effect sizes between subscales following ACLR was found. Conclusions: We found the Polish version of the KOOS to be a valid and reliable instrument for use in patient groups having ACLR. We caution against monitoring individual patients since the smallest change considered clinically relevant cannot reliably be detected.

Elena Losina - One of the best experts on this subject based on the ideXlab platform.

  • effectiveness of Knee Injury and anterior cruciate ligament tear prevention programs a meta analysis
    PLOS ONE, 2015
    Co-Authors: Laurel A Donnellfink, Kristina M Klara, Jamie E Collins, Heidi Y Yang, Melissa G Goczalk, Jeffrey N Katz, Elena Losina
    Abstract:

    Objective Individuals frequently involved in jumping, pivoting or cutting are at increased risk of Knee Injury, including anterior cruciate ligament (ACL) tears. We sought to use meta-analytic techniques to establish whether neuromuscular and proprioceptive training is efficacious in preventing Knee and ACL Injury and to identify factors related to greater efficacy of such programs. Methods We performed a systematic literature search of studies published in English between 1996 and 2014. Intervention efficacy was ascertained from incidence rate ratios (IRRs) weighted by their precision (1/variance) using a random effects model. Separate analyses were performed for Knee and ACL Injury. We examined whether year of publication, study quality, or specific components of the intervention were associated with efficacy of the intervention in a meta-regression analysis. Results Twenty-four studies met the inclusion criteria and were used in the meta-analysis. The mean study sample was 1,093 subjects. Twenty studies reported data on Knee Injury in general terms and 16 on ACL Injury. Maximum Jadad score was 3 (on a 0–5 scale). The summary incidence rate ratio was estimated at 0.731 (95% CI: 0.614, 0.871) for Knee Injury and 0.493 (95% CI: 0.285, 0.854) for ACL Injury, indicating a protective effect of intervention. Meta-regression analysis did not identify specific intervention components associated with greater efficacy but established that later year of publication was associated with more conservative estimates of intervention efficacy. Conclusion The current meta-analysis provides evidence that neuromuscular and proprioceptive training reduces Knee Injury in general and ACL Injury in particular. Later publication date was associated with higher quality studies and more conservative efficacy estimates. As study quality was generally low, these data suggest that higher quality studies should be implemented to confirm the preventive efficacy of such programs.

  • effectiveness of Knee Injury and anterior cruciate ligament tear prevention programs a meta analysis
    PLOS ONE, 2015
    Co-Authors: Laurel A Donnellfink, Jamie E Collins, Heidi Y Yang, Melissa G Goczalk, Jeffrey N Katz, Elena Losina, Kristina Klara
    Abstract:

    Objective Individuals frequently involved in jumping, pivoting or cutting are at increased risk of Knee Injury, including anterior cruciate ligament (ACL) tears. We sought to use meta-analytic techniques to establish whether neuromuscular and proprioceptive training is efficacious in preventing Knee and ACL Injury and to identify factors related to greater efficacy of such programs.

Jackie L Whittaker - One of the best experts on this subject based on the ideXlab platform.

  • What Does the Future Hold? Health-Related Quality of Life 3–12 Years Following a Youth Sport-Related Knee Injury
    'MDPI AG', 2021
    Co-Authors: Clodagh M. Toomey, Carolyn A Emery, Jackie L Whittaker
    Abstract:

    Knee trauma can lead to poor health-related quality of life (HRQoL) and osteoarthritis. We aimed to assess HRQoL 3–12 years following youth sport-related Knee Injury considering HRQoL and osteoarthritis determinants. Generic (EQ-5D-5L index, EQ-VAS) and condition-specific (Knee Injury and Osteoarthritis Outcome Score quality of life subscale, KOOS QOL) HRQoL were assessed in 124 individuals 3–12 years following youth sport-related Knee Injury and 129 uninjured controls of similar age, sex, and sport. Linear regression examined differences in HRQoL outcomes by Injury group. Multivariable linear regression explored the influence of sex, time-since-Injury, Injury type, body mass index, Knee muscle strength, Intermittent and Constant Osteoarthritis Pain (ICOAP) score, and Godin Leisure-Time Exercise Questionnaire (GLTEQ) moderate-to-strenuous physical activity. Participant median (range) age was 23 years (14–29) and 55% were female. Injury history was associated with poorer KOOS QOL (−8.41; 95%CI −10.76, −6.06) but not EQ-5D-5L (−0.0074; −0.0238, 0.0089) or EQ-VAS (−3.82; −8.77, 1.14). Injury history (−5.14; −6.90, −3.38), worse ICOAP score (−0.40; −0.45, −0.36), and anterior cruciate ligament tear (−1.41; −2.77, −0.06) contributed to poorer KOOS QOL. Worse ICOAP score contributed to poorer EQ-5D-5L (−0.0024; −0.0034, −0.0015) and higher GLTEQ moderate-to-strenuous physical activity to better EQ-VAS (0.10; 0.03, 0.17). Knee trauma is associated with poorer condition-specific but not generic HRQoL 3–12 years post-Injury

  • quantification of triple single leg hop test temporospatial parameters a validated method using body worn sensors for functional evaluation after Knee Injury
    Sensors, 2020
    Co-Authors: Niloufar Ahmadian, Jackie L Whittaker, Milad Nazarahari, Hossein Rouhani
    Abstract:

    Lower extremity kinematic alterations associated with sport-related Knee injuries may contribute to an unsuccessful return to sport or early-onset post-traumatic osteoarthritis. Also, without access to sophisticated motion-capture systems, temporospatial monitoring of horizontal hop tests during clinical assessments is limited. By applying an alternative measurement system of two inertial measurement units (IMUs) per limb, we obtained and validated flying/landing times and hop distances of triple single-leg hop (TSLH) test against motion-capture cameras, assessed these temporospatial parameters amongst injured and uninjured groups, and investigated their association with the Knee Injury and Osteoarthritis Outcome Score (KOOS). Using kinematic features of IMU recordings, strap-down integration, and velocity correction techniques, temporospatial parameters were validated for 10 able-bodied participants and compared between 22 youth with sport-related Knee injuries and 10 uninjured youth. With median (interquartile range) errors less than 10(16) ms for flying/landing times, and less than 4.4(5.6)% and 2.4(3.0)% of reference values for individual hops and total TSLH progression, differences between hopping biomechanics of study groups were highlighted. For injured participants, second flying time and all hop distances demonstrated moderate to strong correlations with KOOS Symptom and Function in Daily Living scores. Detailed temporospatial monitoring of hop tests is feasible using the proposed IMUs system.

  • psychological social and contextual factors across recovery stages following a sport related Knee Injury a scoping review
    British Journal of Sports Medicine, 2020
    Co-Authors: Linda K Truong, Amber D Mosewich, Christopher J Holt, Maxi Miciak, Jackie L Whittaker
    Abstract:

    Objective To explore the role of psychological, social and contextual factors across the recovery stages (ie, acute, rehabilitation or return to sport (RTS)) following a traumatic time-loss sport-related Knee Injury. Material and methods This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews and Arksey and O’Malley framework. Six databases were searched using predetermined search terms. Included studies consisted of original data written in English that identified or described a psychological, social or contextual factor related to recovery after a traumatic time-loss sport-related Knee Injury. Two authors independently conducted title–abstract and full-text reviews. Study quality was assessed using the Mixed Methods Appraisal Tool. Thematic analysis was undertaken. Results Of 7289 records, 77 studies representing 5540 participants (37% women, 84% anterior cruciate ligament tears, aged 14–60 years) were included. Psychological factors were investigated across all studies, while social and contextual factors were assessed in 39% and 21% of included studies, respectively. A cross-cutting concept of individualisation was present across four psychological (barriers to progress, active coping, independence and recovery expectations), two social (social support and engagement in care) and two contextual (environmental influences and sport culture) themes. Athletes report multiple barriers to recovery and valued their autonomy, having an active role in their recovery and diverse social support. Conclusion Diverse psychological, social and contextual factors are present and influence all stages of recovery following a traumatic sport-related Knee Injury. A better understanding of these factors at the time of Injury and throughout rehabilitation could assist with optimising Injury management, promoting RTS, and long-term health-related quality-of-life.

  • quadriceps hamstrings intermuscular coherence during single leg squatting 3 12 years following a youth sport related Knee Injury
    Human Movement Science, 2019
    Co-Authors: Maurice Mohr, Vinzenz Von Tscharner, Jackie L Whittaker, Carolyn A Emery, Benno M Nigg
    Abstract:

    Abstract The purpose of this study was to determine the degree of co-contraction as per electromyographic gamma-band intermuscular coherence of the quadricep (Q) and hamstring (H) muscles during single-leg squatting (SLS), and to assess the influence of sex and self-reported Knee complaints on the association between Knee Injury history and medial and lateral Q-H intermuscular coherence. Participants included 34 individuals who suffered a youth sport-related intra-articular Knee Injury 3–12 years previously, and 37 individuals with no Knee Injury history. Surface electromyographic signals were recorded from medial and lateral thigh muscles bilaterally to determine the gamma-band (30–60 Hz) intermuscular coherence between medial and lateral Q-H muscle pairs during SLS. Multivariable linear regression (α = 0.05) was performed to investigate the relationship between Knee Injury history (main exposure) and medial and lateral Q-H coherence (outcome) while accounting for the influence of sex and self-reported Knee pain and symptoms (covariates). The median age of participants was 25 (range 18–30) and 67% were female. Q-H gamma-band coherence was present for 60–90% of legs. Medial and lateral Q-H coherence was higher in females compared to males. There was no evidence for an association between medial Q-H coherence, Knee Injury history, Knee pain, or symptoms. There was evidence for an association between Knee Injury history and lateral Q-H coherence, which was modified by sex such that previously injured males demonstrated reduced Q-H coherence compared to uninjured males. These finding suggest that females demonstrate a more pronounced Q-H co-contraction strategy during a SLS than males regardless of Knee Injury history. Further, that male who suffered a youth sport-related Knee Injury 3–12 years previously demonstrate less Q-H co-contraction during a SLS than uninjured males. The mechanisms behind differences in neuromuscular control between males and females as well as previously injured and uninjured males require further investigation.

  • association between mri defined osteoarthritis pain function and strength 3 10 years following Knee joint Injury in youth sport
    British Journal of Sports Medicine, 2018
    Co-Authors: Jackie L Whittaker, Clodagh Toomey, Linda J Woodhouse, Jacob L Jaremko, Alberto Nettelaguirre, Carolyn A Emery
    Abstract:

    Background Youth and young adults who participate in sport have an increased risk of Knee Injury and subsequent osteoarthritis. Improved understanding of the relationship between structural and clinical outcomes postInjury could inform targeted osteoarthritis prevention interventions. This secondary analysis examines the association between MRI-defined osteoarthritis and self-reported and functional outcomes, 3–10 years following youth sport-related Knee Injury in comparison to healthy controls. Methods Participants included a subsample (n=146) of the Alberta Youth Prevention of Early Osteoarthritis cohort: specifically, 73 individuals with 3–10years history of sport-related intra-articular Knee Injury and 73 age-matched, sex-matched and sport-matched controls with completed MRI studies. Outcomes included: MRI-defined osteoarthritis, radiographic osteoarthritis, Knee Injury and Osteoarthritis Outcome Score, Intermittent and Constant Osteoarthritis Pain, Knee extensor/flexor strength, triple-hop and Y-balance test. Descriptive statistics and univariate logistic regression were used to compare those with and without MRI-defined osteoarthritis. Associations between MRI-defined osteoarthritis and each outcome were assessed using multivariable linear regression considering the influence of Injury history, sex, body mass index and time since Injury. Results Participant median age was 23 years (range 15–27), and 63% were female. MRI-defined osteoarthritis varied by Injury history, Injury type and surgical history and was not isolated to participants with ACL and/or meniscal injuries. Those with a previous Knee Injury had 10-fold (95% CI 2.3 to 42.8) greater odds of MRI-defined osteoarthritis than uninjured participants. MRI-defined osteoarthritis was independently significantly associated with quality of life, but not symptoms, strength or function. Summary MRI-detected structural changes 3– 10 years following youth sport-related Knee Injury may not dictate clinical symptomatology, strength or function but may influence quality of life.

Jon Karlsson - One of the best experts on this subject based on the ideXlab platform.

David J Hunter - One of the best experts on this subject based on the ideXlab platform.

  • does age influence the risk of incident Knee osteoarthritis after a traumatic anterior cruciate ligament Injury
    American Journal of Sports Medicine, 2016
    Co-Authors: David J Hunter, Victoria L Johnson, Justin P Roe, Lucy J Salmon, Leo A Pinczewski
    Abstract:

    Background:The development of radiographic Knee osteoarthritis (OA) after an anterior cruciate ligament (ACL) rupture has long been studied and proven in the adolescent population. However, similar exhaustive investigations have not been conducted in mature-aged athletes or in older populations.Purpose:To identify whether an older adult population had an increased risk of incident radiographic Knee OA after a traumatic Knee Injury compared with a young adult population.Study Design:Cohort study; Level of evidence, 3.Methods:Patients with ACL ruptures who underwent primary reconstruction were enrolled in a prospective, longitudinal single-center study over 15 years. The adult cohort was defined as participants aged ≥35 years who had a Knee Injury resulting in an ACL tear, the adolescent-young cohort suffered similar Knee injuries and were aged ≤25 years, and a third cohort of participants aged 26 to 34 years who suffered a Knee Injury was included to identify the existence of any age-related dose-response ...

  • examining the minimal important difference of patient reported outcome measures for individuals with Knee osteoarthritis a model using the Knee Injury and osteoarthritis outcome score
    The Journal of Rheumatology, 2016
    Co-Authors: Kathryn Mills, Ewa M Roos, Justine M Naylor, Jillian P Eyles, David J Hunter
    Abstract:

    Objective. To examine the influence of different analytical methods, baseline covariates, followup periods, and anchor questions when establishing a minimal important difference (MID) for individuals with Knee osteoarthritis (OA). Second, to propose MID for improving and worsening on the Knee Injury and Osteoarthritis Outcome Score (KOOS). Methods. Retrospective analysis of prospectively collected data from 272 patients with Knee OA undergoing a multidisciplinary nonsurgical management strategy. The magnitude and rate of change as well as the influence of baseline covariates were examined for 5 KOOS subscales over 52 weeks. The MID for improving and worsening were investigated using 4 anchor-based methods. Results. Waitlisted for joint replacement and exhibiting unilateral/bilateral symptoms influenced change in KOOS over time. Generally, low correlations between anchors and KOOS change scores limited calculations of MID; thus, they were only proposed for the pain, activities of daily living, and quality of life subscales. The method used to calculate the MID influenced the cutpoint; however, the type of anchor question only influenced the MID when analyzed with a particular mean change method. Depending on patient and clinical characteristics, the subscale, and the analytical approach used, the MID for KOOS improvement ranged from an absolute change of −1.5 to 20.6 points and worsening ranged from −19.17 to 8.5 points. Conclusion. MID vary with patient and clinical characteristics, KOOS subscale, and analytical approach. Provided the anchor question is relevant to the patient-reported outcome and baseline status is considered, the anchor does not appear to influence the MID for improvement or worsening when using some anchor-based methods.