Langerhans Cell Histiocytosis

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Jonathan N Glickman - One of the best experts on this subject based on the ideXlab platform.

  • gastrointestinal tract involvement in Langerhans Cell Histiocytosis case report and literature review
    Pediatrics, 2006
    Co-Authors: Elizabeth J Hait, Marilyn G Liang, Barbara A Degar, Jonathan N Glickman
    Abstract:

    Digestive tract involvement in Langerhans Cell Histiocytosis is exceedingly rare. We report a case of Langerhans Cell Histiocytosis in an otherwise thriving neonate presenting with hematochezia, anemia, and rash. We also review the few cases of Langerhans Cell Histiocytosis with gastrointestinal involvement reported in the English-language medical literature. Although gastrointestinal involvement can range in severity from mild to life-threatening, its presence may be indicative of multisystemic disease, and aggressive treatment should be considered.

Elizabeth J Hait - One of the best experts on this subject based on the ideXlab platform.

  • gastrointestinal tract involvement in Langerhans Cell Histiocytosis case report and literature review
    Pediatrics, 2006
    Co-Authors: Elizabeth J Hait, Marilyn G Liang, Barbara A Degar, Jonathan N Glickman
    Abstract:

    Digestive tract involvement in Langerhans Cell Histiocytosis is exceedingly rare. We report a case of Langerhans Cell Histiocytosis in an otherwise thriving neonate presenting with hematochezia, anemia, and rash. We also review the few cases of Langerhans Cell Histiocytosis with gastrointestinal involvement reported in the English-language medical literature. Although gastrointestinal involvement can range in severity from mild to life-threatening, its presence may be indicative of multisystemic disease, and aggressive treatment should be considered.

H Dalichau - One of the best experts on this subject based on the ideXlab platform.

  • pulmonary Langerhans Cell Histiocytosis Histiocytosis x following metastasizing malignant melanoma
    Swiss Medical Weekly, 2002
    Co-Authors: Theodor Tirilomis, Dieter Zenker, Masoud Mirzaie, H Dalichau
    Abstract:

    Background: Pulmonary Langerhans' Cell Histiocytosis (Histiocytosis X) is an uncommon, diffuse interstitial lung disease of unknown cause, mostly presenting in young smokers. Association of pulmonary Langerhans' Cell Histiocytosis with a malignant neoplasm is rare. Case description and results: We present and discuss the case of a 48-year-old man (ex-smoker) with metastasising malignant melanoma. A few months after chemotherapy and a modified Whipple procedure for retroduodenal metastasis of a malignant melanoma, computer tomographic scans revealed intrapulmonary "ring-shaped structures". Endobronchial biopsies and bronchioalveolar lavage showed no evidence of neoplasm or inflammation. Open-lung biopsy was performed and revealed pulmonary Langerhans' Cell Histiocytosis. Conclusion: To our knowledge this is the first reported case of pulmonary Langerhans' Cell Histiocytosis in association with malignant melanoma. Chemotherapy for malignant melanoma may be related to the development of pulmonary Langerhans' Cell Histiocytosis.

Marilyn G Liang - One of the best experts on this subject based on the ideXlab platform.

  • gastrointestinal tract involvement in Langerhans Cell Histiocytosis case report and literature review
    Pediatrics, 2006
    Co-Authors: Elizabeth J Hait, Marilyn G Liang, Barbara A Degar, Jonathan N Glickman
    Abstract:

    Digestive tract involvement in Langerhans Cell Histiocytosis is exceedingly rare. We report a case of Langerhans Cell Histiocytosis in an otherwise thriving neonate presenting with hematochezia, anemia, and rash. We also review the few cases of Langerhans Cell Histiocytosis with gastrointestinal involvement reported in the English-language medical literature. Although gastrointestinal involvement can range in severity from mild to life-threatening, its presence may be indicative of multisystemic disease, and aggressive treatment should be considered.

Barbara A Degar - One of the best experts on this subject based on the ideXlab platform.

  • gastrointestinal tract involvement in Langerhans Cell Histiocytosis case report and literature review
    Pediatrics, 2006
    Co-Authors: Elizabeth J Hait, Marilyn G Liang, Barbara A Degar, Jonathan N Glickman
    Abstract:

    Digestive tract involvement in Langerhans Cell Histiocytosis is exceedingly rare. We report a case of Langerhans Cell Histiocytosis in an otherwise thriving neonate presenting with hematochezia, anemia, and rash. We also review the few cases of Langerhans Cell Histiocytosis with gastrointestinal involvement reported in the English-language medical literature. Although gastrointestinal involvement can range in severity from mild to life-threatening, its presence may be indicative of multisystemic disease, and aggressive treatment should be considered.