The Experts below are selected from a list of 171 Experts worldwide ranked by ideXlab platform

Jeffrey M. Weinberg - One of the best experts on this subject based on the ideXlab platform.

  • Cutaneous tuberculosis: diagnosis and treatment.
    American journal of clinical dermatology, 2002
    Co-Authors: Joseph Barbagallo, Patricia Tager, Rosemary Ingleton, Ranella J. Hirsch, Jeffrey M. Weinberg
    Abstract:

    As we move into the 21st century, cutaneous tuberculosis has re-emerged in areas with a high incidence of HIV infection and multi-drug resistant pulmonary tuberculosis. Mycobacterium tuberculosis, Mycobacterium bovis, and the BCG vaccine cause tuberculosis involving the skin. True cutaneous tuberculosis lesions can be acquired either exogenously or endogenously, show a wide spectrum of morphology and M. tuberculosis can be diagnosed by acid-fast bacilli (AFB) stains, culture or polymerase chain reaction (PCR). These lesions include tuberculous chancre, tuberculosis verrucosa cutis, lupus vulgaris, scrofuloderma, orificial tuberculosis, miliary tuberculosis, metastatic tuberculosis abscess and most cases of papulonecrotic tuberculid. The tuberculids, like cutaneous tuberculosis, show a wide spectrum of morphology but M. tuberculosis is not identified by AFB stains, culture or PCR. These lesions include Lichen Scrofulosorum, nodular tuberculid, most cases of nodular granulomatous phlebitis, most cases of erythema induratum of Bazin and some cases of papulonecrotic tuberculid. Diagnosis of cutaneous tuberculosis is challenging and requires the correlation of clinical findings with diagnostic testing; in addition to traditional AFB smears and cultures, there has been increased utilization of PCR because of its rapidity, sensitivity and specificity. Since most cases of cutaneous tuberculosis are a manifestation of systemic involvement, and the bacillary load in cutaneous tuberculosis is usually less than in pulmonary tuberculosis, treatment regimens are similar to that of tuberculosis in general. In the immunocompromised, such as an HIV infected patient with disseminated miliary tuberculosis, rapid diagnosis and prompt initiation of treatment are paramount. Unfortunately, despite even the most aggressive efforts, the prognosis in these individuals is poor when multi-drug resistant mycobacterium are present. An increased awareness of the re-emergence of cutaneous tuberculosis will allow for the proper diagnosis and management of this increasingly common skin disorder.

Baikkee Cho - One of the best experts on this subject based on the ideXlab platform.

Eishin Morita - One of the best experts on this subject based on the ideXlab platform.

  • Lichen Scrofulosorum caused by pulmonary mycobacterium avium complex mac infection
    European Journal of Dermatology, 2011
    Co-Authors: Reiko Tobita, Yasuyuki Sumikawa, Kaoru Imaoka, Susumu Murata, Itaru Dekio, Riruke Maruyama, Eishin Morita
    Abstract:

    ejd.2011.1377 Auteur(s) : Reiko Tobita1 reiko.kikkawa@sunny.ocn.ne.jp, Yasuyuki Sumikawa1, Kaoru Imaoka1, Susumu Murata1, Itaru Dekio1, Riruke Maruyama2, Eishin Morita1 1 Department of Dermatology, Shimane University School of Medicine, 89-1 Enya-cho Izumo, Shimane 693-8501, Japan 2 Department of Organ Pathology, Shimane University School of Medicine, 89-1 Enya-cho Izumo, Shimane 693-8501, Japan Lichen Scrofulosorum (LS) is a rare tuberculid that usually develops in children and young adults. It [...]

Befon A - One of the best experts on this subject based on the ideXlab platform.

  • Lichen Scrofulosorum in a Patient with Tuberculous Cervical Lymphadenopathy: A case report
    Epidemiology, 2017
    Co-Authors: Kostopoulos N, Tzanetakou, Platsidaki E, Theologi, Christofidou E, Befon A
    Abstract:

    Introduction: Cutaneous tuberculosis (CTB) is a rare presentation of extrapulmonary tuberculosis (TB) with various clinical manifestations. Tuberculids, a type of CTB, are probably the result of hyperergic immune reaction induced by Mycobacterium tuberculosis. Lichen Scrofulosorum (LS) is a rare tuberculid mostly seen in children and young adults with or without other manifestations of tuberculosis. Case report: We present a 30 year old patient presented with a papular eruption on his trunk and upper extremities. The patient had recently started on a 4 drug-regimen treatment for a diagnosed tuberculous cervical lymphadenitis and he was under investigation for pulmonary TB. Histopathology of the papular lesions showed epithelioid granulomas strongly indicating Lichen Scrofulosorum. The eruption responded to antitubercular therapy with complete clearance of the lesions. Discussion: The tuberculids are a form of CTB caused by hypersensitivity reactions to Mycobacterium tuberculosis. The diagnosis of LS is problematic and frequently delayed because of its rarity and clinical similarity to many other more common skin conditions.

Joseph Barbagallo - One of the best experts on this subject based on the ideXlab platform.

  • Cutaneous tuberculosis: diagnosis and treatment.
    American journal of clinical dermatology, 2002
    Co-Authors: Joseph Barbagallo, Patricia Tager, Rosemary Ingleton, Ranella J. Hirsch, Jeffrey M. Weinberg
    Abstract:

    As we move into the 21st century, cutaneous tuberculosis has re-emerged in areas with a high incidence of HIV infection and multi-drug resistant pulmonary tuberculosis. Mycobacterium tuberculosis, Mycobacterium bovis, and the BCG vaccine cause tuberculosis involving the skin. True cutaneous tuberculosis lesions can be acquired either exogenously or endogenously, show a wide spectrum of morphology and M. tuberculosis can be diagnosed by acid-fast bacilli (AFB) stains, culture or polymerase chain reaction (PCR). These lesions include tuberculous chancre, tuberculosis verrucosa cutis, lupus vulgaris, scrofuloderma, orificial tuberculosis, miliary tuberculosis, metastatic tuberculosis abscess and most cases of papulonecrotic tuberculid. The tuberculids, like cutaneous tuberculosis, show a wide spectrum of morphology but M. tuberculosis is not identified by AFB stains, culture or PCR. These lesions include Lichen Scrofulosorum, nodular tuberculid, most cases of nodular granulomatous phlebitis, most cases of erythema induratum of Bazin and some cases of papulonecrotic tuberculid. Diagnosis of cutaneous tuberculosis is challenging and requires the correlation of clinical findings with diagnostic testing; in addition to traditional AFB smears and cultures, there has been increased utilization of PCR because of its rapidity, sensitivity and specificity. Since most cases of cutaneous tuberculosis are a manifestation of systemic involvement, and the bacillary load in cutaneous tuberculosis is usually less than in pulmonary tuberculosis, treatment regimens are similar to that of tuberculosis in general. In the immunocompromised, such as an HIV infected patient with disseminated miliary tuberculosis, rapid diagnosis and prompt initiation of treatment are paramount. Unfortunately, despite even the most aggressive efforts, the prognosis in these individuals is poor when multi-drug resistant mycobacterium are present. An increased awareness of the re-emergence of cutaneous tuberculosis will allow for the proper diagnosis and management of this increasingly common skin disorder.