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Jae Seog Hyun - One of the best experts on this subject based on the ideXlab platform.

  • Location of Brain Electrical Source Activation by Visually Stimulated Sexual Arousal in Young Men and Women: a Cross Spectral Analysis using Low Resolution Brain Electromagnetic Tomography (LORETA)
    Korean Journal of Urology, 2007
    Co-Authors: Sung Chul Kam, Oh-young Kwon, Jae Seog Hyun
    Abstract:

    Purpose: To investigate the locations of the cerebral cortex activated by visually stimulated sexual arousal, and to discriminate the gender differences between the cortical activation patterns in response to sexual stimuli. Materials and Methods: Thirty-two male and the twenty-one female volunteers from right-handed medical students were enrolled in this study. The electroencephalography (EEGs) included the segments recorded during resting, watching a music-video, intermission and watching a pornographic video. The low-resolution brain electromagnetic tomography (LORETA) images of cross-spectral analysis were obtained from the segments using the LORETA-KEY software. Results: The beta 1, 2 and 3 activities of males showed the point of maximal current densities in both the uncus and parahippocampal gyrus of the left Limbic Lobe, the anterior cingulate of the right Limbic Lobe, the superior temporal gyrus of both temporal Lobes, the precuneus of the right parietal Lobe, the medial frontal gyrus and superior frontal gyrus of the right frontal Lobe, the superior parietal lobule of the right parietal Lobe, and the middle occipital gyrus of both occipital Lobes. The delta, theta, alpha and beta 1 activities of females showed the point of maximal current densities in the postcentral gyrus and inferior parietal lobule of the left parietal Lobe, the middle frontal gyrus of the left frontal Lobe, the middle occipital gyrus of the left occipital Lobe, the left cuneus, the superior temporal gyrus of both temporal Lobes and the left parahippocampal gyrus. Conclusions: There was a difference in the visually stimulated sexual arousal-associated with the cerebral neuroanatomical areas between men and women, as estimated using the LORETA software. These areas; therefore, were thought to play important roles in the sexual arousal of males and females in response to audiovisual sexual stimulation. (Korean J Urol 2007;48:333-343)

  • Location of Brain Electrical Source Activation according to Visually Stimulated Sexual Arousal: A Cross Spectral Analysis using Low Resolution Brain Electromagnetic Tomography (LORETA)
    Korean Journal of Urology, 2006
    Co-Authors: Sung Chul Kam, See Min Choi, S.u. Jeh, Jeong Seok Hwa, Ky Hyun Jung, Suk Won Jeong, Oh-young Kwon, Jae Seog Hyun
    Abstract:

    Purpose: Low resolution brain electromagnetic tomography (LORETA) is a kind of functional imaging technique and it is also an up-to-date technique for conducting electroencephalography (EEG) analysis. We tried to investigate the locations on the cerebral cortex that are activated by visually stimulated sexual arousal. Materials and Methods: Thirty-three male volunteers (age range: 24.7±1.7 years) among all the right-handed medical students at our university were enrolled in this study. The EEGs included the segments recorded during resting, watching a music-video, intermission and watching a porno-video. The LORETA images of the cross-spectral analysis were obtained with using segments of LORETA-KEY (KEY Institute for Brain-Mind Research, Switzerland) software. Results: In the statistical nonparam etric m aps (SnPM) of each spectrum and the delta, theta and alpha waves did not show the increased current density. The beta 1, 2 and 3 activity showed the point of maximal current densities in the anterior parahippocampal gyrus of the left Limbic Lobe and the superior temporal gyrus of both temporal Lobes, the superior temporal gyrus of the right temporal Lobe, the precuneus of the right parietal Lobe, the medial frontal gyrus of the left frontal Lobe, the middle occipital gyrus of the right occipital Lobe, the superior temporal gyrus of both temporal Lobes and the superior frontal gyrus of the right frontal Lobe. Conclusions: The sexual arousal by visual stimulation may activate the anterior parahippocampal gyrus of the left Limbic Lobe, the superior temporal gyrus of both temporal Lobes, the precuneus of the right parietal Lobe, the medial frontal gyrus of the left frontal gyrus, and the middle occipital gyrus of the right occipital Lobe. (Korean J Urol 2006;47:779-785)

Jie Yuan - One of the best experts on this subject based on the ideXlab platform.

  • Herpes zoster chronification to postherpetic neuralgia induces brain activity and grey matter volume change.
    American journal of translational research, 2018
    Co-Authors: Song Cao, Bangyong Qin, Yi Zhang, Jie Yuan, Peng Xie, Ganjun Song
    Abstract:

    OBJECTIVE Herpes zoster (HZ) can develop into postherpetic neuralgia (PHN), which is a chronic neuropathic pain (NP). Whether the chronification from HZ to PHN induced brain functional or structural change is unknown and no study compared the changes of the same brains of patients who transited from HZ to PHN. We minimized individual differences and observed whether the chronification of HZ to PHN induces functional and pain duration dependent grey matter volume (GMV) change in HZ-PHN patients. METHODS To minimize individual differences induced error, we enrolled 12 patients with a transition from HZ to PHN. The functional and structural changes of their brains between the two states were identified with resting-state functional MRI (rs-fMRI) technique (i.e., the regional homogeneity (ReHo) and fractional aptitude of low-frequency fluctuation (fALFF) method) and the voxel based morphometry (VBM) technology respectively. The correlations between MRI parameters (i.e., ΔReHo, ΔfALFF and ΔVBM) and Δpain duration were analyzed too. RESULTS Compared with HZ brains, PHN brains exhibited abnormal ReHo, fALFF and VBM values in pain matrix (the frontal Lobe, parietal Lobe, thalamus, Limbic Lobe and cerebellum) as well as the occipital Lobe and temporal Lobe. Nevertheless, the activity of vast area of cerebellum and frontal Lobe significantly increased while that of occipital Lobe and Limbic Lobe showed apparent decrease when HZ developed to PHN. In addition, PHN brain showed decreased GMV in the frontal Lobe, the parietal Lobe and the occipital Lobe but increased in the cerebellum and the temporal Lobe. Correlation analyses showed that some of the ReHo, fALFF and VBM differential areas (such as the cerebellum posterior Lobe, the thalamus extra-nuclear and the middle temporal gyrus) correlated well with Δpain duration. CONCLUSIONS HZ chronification induced functional and structural change in cerebellum, occipital Lobe, temporal Lobe, parietal Lobe and Limbic Lobe. These changes may be correlated with HZ-PHN chronification. In addition, these changes could be reasons of refractory chronic pain of PHN.

  • Local Brain Activity Differences Between Herpes Zoster and Postherpetic Neuralgia Patients: A Resting-State Functional MRI Study.
    Pain physician, 2017
    Co-Authors: Song Cao, Bangyong Qin, Yi Zhang, Peng Xie, Wenwen Deng, Jie Yuan
    Abstract:

    Background Herpes zoster (HZ) can develop into postherpetic neuralgia (PHN), both of which are painful diseases. PHN patients suffer chronic pain and emotional disorders. Previous studies showed that the PHN brain displayed abnormal activity and structural change, but the difference in brain activity between HZ and PHN is still not known. Objectives To identify regional brain activity changes in HZ and PHN brains with resting-state functional magnetic resonance imaging (rs-fMRI) technique, and to observe the differences between HZ and PHN patients. Study design Observational study. Setting University hospital. Methods Regional homogeneity (ReHo) and fractional aptitude of low-frequency fluctuation (fALFF) methods were employed to analysis resting-state brain activity. Seventy-three age and gender matched patients (50 HZ, 23 PHN) and 55 healthy controls were enrolled. ReHo and fALFF changes were analyzed to detect the functional abnormality in HZ and PHN brains. Results Compared with healthy controls, HZ and PHN patients exhibited abnormal ReHo and fALFF values in classic pain-related brain regions (such as the frontal Lobe, thalamus, insular, and cerebellum) as well as the brainstem, Limbic Lobe, and temporal Lobe. When HZ developed to PHN, the activity in the vast area of the cerebellum significantly increased while that of some regions in the occipital Lobe, temporal Lobe, parietal Lobe, and Limbic Lobe showed an apparent decrease. Limitations (a) Relatively short pain duration (mean 12.2 months) and small sample size (n = 23) for PHN group. (b) Comparisons at different time points (with paired t-tests) for each patient may minimize individual differences. Conclusions HZ and PHN induced local brain activity changed in the pain matrix, brainstem, and Limbic system. HZ chronification induced functional change in the cerebellum, occipital Lobe, temporal Lobe, parietal Lobe, and Limbic Lobe. These brain activity changes may be correlated with HZ-PHN transition. Key words Herpes zoster, postherpetic neuralgia, resting-state fMRI (rs-fMRI), regional homogeneity (ReHo), fractional aptitude of low-frequency fluctuation (fALFF).

Sung Chul Kam - One of the best experts on this subject based on the ideXlab platform.

  • Location of Brain Electrical Source Activation by Visually Stimulated Sexual Arousal in Young Men and Women: a Cross Spectral Analysis using Low Resolution Brain Electromagnetic Tomography (LORETA)
    Korean Journal of Urology, 2007
    Co-Authors: Sung Chul Kam, Oh-young Kwon, Jae Seog Hyun
    Abstract:

    Purpose: To investigate the locations of the cerebral cortex activated by visually stimulated sexual arousal, and to discriminate the gender differences between the cortical activation patterns in response to sexual stimuli. Materials and Methods: Thirty-two male and the twenty-one female volunteers from right-handed medical students were enrolled in this study. The electroencephalography (EEGs) included the segments recorded during resting, watching a music-video, intermission and watching a pornographic video. The low-resolution brain electromagnetic tomography (LORETA) images of cross-spectral analysis were obtained from the segments using the LORETA-KEY software. Results: The beta 1, 2 and 3 activities of males showed the point of maximal current densities in both the uncus and parahippocampal gyrus of the left Limbic Lobe, the anterior cingulate of the right Limbic Lobe, the superior temporal gyrus of both temporal Lobes, the precuneus of the right parietal Lobe, the medial frontal gyrus and superior frontal gyrus of the right frontal Lobe, the superior parietal lobule of the right parietal Lobe, and the middle occipital gyrus of both occipital Lobes. The delta, theta, alpha and beta 1 activities of females showed the point of maximal current densities in the postcentral gyrus and inferior parietal lobule of the left parietal Lobe, the middle frontal gyrus of the left frontal Lobe, the middle occipital gyrus of the left occipital Lobe, the left cuneus, the superior temporal gyrus of both temporal Lobes and the left parahippocampal gyrus. Conclusions: There was a difference in the visually stimulated sexual arousal-associated with the cerebral neuroanatomical areas between men and women, as estimated using the LORETA software. These areas; therefore, were thought to play important roles in the sexual arousal of males and females in response to audiovisual sexual stimulation. (Korean J Urol 2007;48:333-343)

  • Location of Brain Electrical Source Activation according to Visually Stimulated Sexual Arousal: A Cross Spectral Analysis using Low Resolution Brain Electromagnetic Tomography (LORETA)
    Korean Journal of Urology, 2006
    Co-Authors: Sung Chul Kam, See Min Choi, S.u. Jeh, Jeong Seok Hwa, Ky Hyun Jung, Suk Won Jeong, Oh-young Kwon, Jae Seog Hyun
    Abstract:

    Purpose: Low resolution brain electromagnetic tomography (LORETA) is a kind of functional imaging technique and it is also an up-to-date technique for conducting electroencephalography (EEG) analysis. We tried to investigate the locations on the cerebral cortex that are activated by visually stimulated sexual arousal. Materials and Methods: Thirty-three male volunteers (age range: 24.7±1.7 years) among all the right-handed medical students at our university were enrolled in this study. The EEGs included the segments recorded during resting, watching a music-video, intermission and watching a porno-video. The LORETA images of the cross-spectral analysis were obtained with using segments of LORETA-KEY (KEY Institute for Brain-Mind Research, Switzerland) software. Results: In the statistical nonparam etric m aps (SnPM) of each spectrum and the delta, theta and alpha waves did not show the increased current density. The beta 1, 2 and 3 activity showed the point of maximal current densities in the anterior parahippocampal gyrus of the left Limbic Lobe and the superior temporal gyrus of both temporal Lobes, the superior temporal gyrus of the right temporal Lobe, the precuneus of the right parietal Lobe, the medial frontal gyrus of the left frontal Lobe, the middle occipital gyrus of the right occipital Lobe, the superior temporal gyrus of both temporal Lobes and the superior frontal gyrus of the right frontal Lobe. Conclusions: The sexual arousal by visual stimulation may activate the anterior parahippocampal gyrus of the left Limbic Lobe, the superior temporal gyrus of both temporal Lobes, the precuneus of the right parietal Lobe, the medial frontal gyrus of the left frontal gyrus, and the middle occipital gyrus of the right occipital Lobe. (Korean J Urol 2006;47:779-785)

Song Cao - One of the best experts on this subject based on the ideXlab platform.

  • Herpes zoster chronification to postherpetic neuralgia induces brain activity and grey matter volume change.
    American journal of translational research, 2018
    Co-Authors: Song Cao, Bangyong Qin, Yi Zhang, Jie Yuan, Peng Xie, Ganjun Song
    Abstract:

    OBJECTIVE Herpes zoster (HZ) can develop into postherpetic neuralgia (PHN), which is a chronic neuropathic pain (NP). Whether the chronification from HZ to PHN induced brain functional or structural change is unknown and no study compared the changes of the same brains of patients who transited from HZ to PHN. We minimized individual differences and observed whether the chronification of HZ to PHN induces functional and pain duration dependent grey matter volume (GMV) change in HZ-PHN patients. METHODS To minimize individual differences induced error, we enrolled 12 patients with a transition from HZ to PHN. The functional and structural changes of their brains between the two states were identified with resting-state functional MRI (rs-fMRI) technique (i.e., the regional homogeneity (ReHo) and fractional aptitude of low-frequency fluctuation (fALFF) method) and the voxel based morphometry (VBM) technology respectively. The correlations between MRI parameters (i.e., ΔReHo, ΔfALFF and ΔVBM) and Δpain duration were analyzed too. RESULTS Compared with HZ brains, PHN brains exhibited abnormal ReHo, fALFF and VBM values in pain matrix (the frontal Lobe, parietal Lobe, thalamus, Limbic Lobe and cerebellum) as well as the occipital Lobe and temporal Lobe. Nevertheless, the activity of vast area of cerebellum and frontal Lobe significantly increased while that of occipital Lobe and Limbic Lobe showed apparent decrease when HZ developed to PHN. In addition, PHN brain showed decreased GMV in the frontal Lobe, the parietal Lobe and the occipital Lobe but increased in the cerebellum and the temporal Lobe. Correlation analyses showed that some of the ReHo, fALFF and VBM differential areas (such as the cerebellum posterior Lobe, the thalamus extra-nuclear and the middle temporal gyrus) correlated well with Δpain duration. CONCLUSIONS HZ chronification induced functional and structural change in cerebellum, occipital Lobe, temporal Lobe, parietal Lobe and Limbic Lobe. These changes may be correlated with HZ-PHN chronification. In addition, these changes could be reasons of refractory chronic pain of PHN.

  • Local Brain Activity Differences Between Herpes Zoster and Postherpetic Neuralgia Patients: A Resting-State Functional MRI Study.
    Pain physician, 2017
    Co-Authors: Song Cao, Bangyong Qin, Yi Zhang, Peng Xie, Wenwen Deng, Jie Yuan
    Abstract:

    Background Herpes zoster (HZ) can develop into postherpetic neuralgia (PHN), both of which are painful diseases. PHN patients suffer chronic pain and emotional disorders. Previous studies showed that the PHN brain displayed abnormal activity and structural change, but the difference in brain activity between HZ and PHN is still not known. Objectives To identify regional brain activity changes in HZ and PHN brains with resting-state functional magnetic resonance imaging (rs-fMRI) technique, and to observe the differences between HZ and PHN patients. Study design Observational study. Setting University hospital. Methods Regional homogeneity (ReHo) and fractional aptitude of low-frequency fluctuation (fALFF) methods were employed to analysis resting-state brain activity. Seventy-three age and gender matched patients (50 HZ, 23 PHN) and 55 healthy controls were enrolled. ReHo and fALFF changes were analyzed to detect the functional abnormality in HZ and PHN brains. Results Compared with healthy controls, HZ and PHN patients exhibited abnormal ReHo and fALFF values in classic pain-related brain regions (such as the frontal Lobe, thalamus, insular, and cerebellum) as well as the brainstem, Limbic Lobe, and temporal Lobe. When HZ developed to PHN, the activity in the vast area of the cerebellum significantly increased while that of some regions in the occipital Lobe, temporal Lobe, parietal Lobe, and Limbic Lobe showed an apparent decrease. Limitations (a) Relatively short pain duration (mean 12.2 months) and small sample size (n = 23) for PHN group. (b) Comparisons at different time points (with paired t-tests) for each patient may minimize individual differences. Conclusions HZ and PHN induced local brain activity changed in the pain matrix, brainstem, and Limbic system. HZ chronification induced functional change in the cerebellum, occipital Lobe, temporal Lobe, parietal Lobe, and Limbic Lobe. These brain activity changes may be correlated with HZ-PHN transition. Key words Herpes zoster, postherpetic neuralgia, resting-state fMRI (rs-fMRI), regional homogeneity (ReHo), fractional aptitude of low-frequency fluctuation (fALFF).

Oh-young Kwon - One of the best experts on this subject based on the ideXlab platform.

  • Location of Brain Electrical Source Activation by Visually Stimulated Sexual Arousal in Young Men and Women: a Cross Spectral Analysis using Low Resolution Brain Electromagnetic Tomography (LORETA)
    Korean Journal of Urology, 2007
    Co-Authors: Sung Chul Kam, Oh-young Kwon, Jae Seog Hyun
    Abstract:

    Purpose: To investigate the locations of the cerebral cortex activated by visually stimulated sexual arousal, and to discriminate the gender differences between the cortical activation patterns in response to sexual stimuli. Materials and Methods: Thirty-two male and the twenty-one female volunteers from right-handed medical students were enrolled in this study. The electroencephalography (EEGs) included the segments recorded during resting, watching a music-video, intermission and watching a pornographic video. The low-resolution brain electromagnetic tomography (LORETA) images of cross-spectral analysis were obtained from the segments using the LORETA-KEY software. Results: The beta 1, 2 and 3 activities of males showed the point of maximal current densities in both the uncus and parahippocampal gyrus of the left Limbic Lobe, the anterior cingulate of the right Limbic Lobe, the superior temporal gyrus of both temporal Lobes, the precuneus of the right parietal Lobe, the medial frontal gyrus and superior frontal gyrus of the right frontal Lobe, the superior parietal lobule of the right parietal Lobe, and the middle occipital gyrus of both occipital Lobes. The delta, theta, alpha and beta 1 activities of females showed the point of maximal current densities in the postcentral gyrus and inferior parietal lobule of the left parietal Lobe, the middle frontal gyrus of the left frontal Lobe, the middle occipital gyrus of the left occipital Lobe, the left cuneus, the superior temporal gyrus of both temporal Lobes and the left parahippocampal gyrus. Conclusions: There was a difference in the visually stimulated sexual arousal-associated with the cerebral neuroanatomical areas between men and women, as estimated using the LORETA software. These areas; therefore, were thought to play important roles in the sexual arousal of males and females in response to audiovisual sexual stimulation. (Korean J Urol 2007;48:333-343)

  • Location of Brain Electrical Source Activation according to Visually Stimulated Sexual Arousal: A Cross Spectral Analysis using Low Resolution Brain Electromagnetic Tomography (LORETA)
    Korean Journal of Urology, 2006
    Co-Authors: Sung Chul Kam, See Min Choi, S.u. Jeh, Jeong Seok Hwa, Ky Hyun Jung, Suk Won Jeong, Oh-young Kwon, Jae Seog Hyun
    Abstract:

    Purpose: Low resolution brain electromagnetic tomography (LORETA) is a kind of functional imaging technique and it is also an up-to-date technique for conducting electroencephalography (EEG) analysis. We tried to investigate the locations on the cerebral cortex that are activated by visually stimulated sexual arousal. Materials and Methods: Thirty-three male volunteers (age range: 24.7±1.7 years) among all the right-handed medical students at our university were enrolled in this study. The EEGs included the segments recorded during resting, watching a music-video, intermission and watching a porno-video. The LORETA images of the cross-spectral analysis were obtained with using segments of LORETA-KEY (KEY Institute for Brain-Mind Research, Switzerland) software. Results: In the statistical nonparam etric m aps (SnPM) of each spectrum and the delta, theta and alpha waves did not show the increased current density. The beta 1, 2 and 3 activity showed the point of maximal current densities in the anterior parahippocampal gyrus of the left Limbic Lobe and the superior temporal gyrus of both temporal Lobes, the superior temporal gyrus of the right temporal Lobe, the precuneus of the right parietal Lobe, the medial frontal gyrus of the left frontal Lobe, the middle occipital gyrus of the right occipital Lobe, the superior temporal gyrus of both temporal Lobes and the superior frontal gyrus of the right frontal Lobe. Conclusions: The sexual arousal by visual stimulation may activate the anterior parahippocampal gyrus of the left Limbic Lobe, the superior temporal gyrus of both temporal Lobes, the precuneus of the right parietal Lobe, the medial frontal gyrus of the left frontal gyrus, and the middle occipital gyrus of the right occipital Lobe. (Korean J Urol 2006;47:779-785)