The Experts below are selected from a list of 159 Experts worldwide ranked by ideXlab platform

G P Lardy - One of the best experts on this subject based on the ideXlab platform.

  • short communication growth and attainment of puberty in calves from cows supplemented with Linseed Meal during late gestation and early lactation
    Canadian Journal of Animal Science, 2012
    Co-Authors: R Ilse, G P Lardy, V L Anderso, D S Uchana, K G Odde, K A Vonnahme
    Abstract:

    Ilse, B. R., Anderson, V. L., Buchanan, D. S., Odde, K. G., Lardy, G. P. and Vonnahme, K. A. 2012. Short Communication: Growth and attainment of puberty in calves from cows supplemented with Linseed Meal during late gestation and early lactation. Can. J. Anim. Sci. 92: 443–447. To test the objective that a Linseed Meal (LSM) supplement in beef cows during late gestation and early lactation would impact offspring growth performance, steer carcass composition, and attainment of puberty in heifer calves, multiparous beef cows received either LSM or a control supplement for the last 60 d of gestation (exp. 1; n=72) or during the first 60 d of lactation (exp. 2; n=91). In both experiments, birth weight, weaning weight, and ADG of calves were not affected (P>0.31) by LSM supplementation. There was no effect (P>0.09) of supplementation on carcass characteristics of steer progeny fed to market weight. In exps. 1 and 2, attainment of puberty in heifer calves was not influenced (P>0.58) by supplement type. Linseed ...

  • impacts of Linseed Meal and estradiol 17β on cellularity angiogenic and vasoactive factor mrna expression and vascularity of the uterus in ovariectomized ewes
    Canadian Journal of Animal Science, 2012
    Co-Authors: R Ilse, G P Lardy, M R Oneil, L P Reynolds, K A Vonnahme
    Abstract:

    Ilse, B. R., O'Neil, M. R., Lardy, G. P., Reynolds, L. P. and Vonnahme, K. A. 2012. Impacts of Linseed Meal and estradiol-17β on cellularity, angiogenic and vasoactive factor mRNA expression, and vascularity of the uterus in ovariectomized ewes. Can. J. Anim. Sci. 92: 297–306. The objective of the current study was to determine the estrogenic potential of the phytoestrogen secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on uterine cell proliferation, vascularity, and angiogenic factor mRNA expression. Ovariectomized ewes (n=48) were fed a diet containing 12.5% LSM for 0, 1, 7, or 14 d and implanted with estradiol-17β (E2) for 0, 6, or 24 h before tissue collection. There was an interaction of LSM×E2 on uterine mass (grams; P=0.03; percentage change; P<0.003). Uterine mass increased (P≤0.02) after 24 h of E2 exposure on days 1, 7, and 14 of LSM feeding, with the greatest mass occurring in ewes exposed to E2 for 24 h and 1 d LSM feeding. Regardless of days fed LSM, after 24 h of E2 exposu...

  • impacts of Linseed Meal and estradiol 17β on cellularity angiogenic and vasoactive factor mrna expression and vascularity of the uterus in ovariectomized ewes
    Canadian Journal of Plant Science, 2012
    Co-Authors: R Ilse, G P Lardy, M R Oneil, L P Reynolds, K A Vonnahme
    Abstract:

    Ilse, B. R., O'Neil, M. R., Lardy, G. P., Reynolds, L. P. and Vonnahme, K. A. 2012. Impacts of Linseed Meal and estradiol-17β on cellularity, angiogenic and vasoactive factor mRNA expression, and vascularity of the uterus in ovariectomized ewes. Can. J. Anim. Sci. 92: 297–306. The objective of the current study was to determine the estrogenic potential of the phytoestrogen secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on uterine cell proliferation, vascularity, and angiogenic factor mRNA expression. Ovariectomized ewes (n=48) were fed a diet containing 12.5% LSM for 0, 1, 7, or 14 d and implanted with estradiol-17β (E2) for 0, 6, or 24 h before tissue collection. There was an interaction of LSM×E2 on uterine mass (grams; P=0.03; percentage change; P<0.003). Uterine mass increased (P≤0.02) after 24 h of E2 exposure on days 1, 7, and 14 of LSM feeding, with the greatest mass occurring in ewes exposed to E2 for 24 h and 1 d LSM feeding. Regardless of days fed LSM, after 24 h of E2 exposure uterine mass was greatest. The greatest percentage increase in uterine mass occurred in ewes exposed to E2 for 24 h and fed 1 d of LSM. Cell proliferation within the uterine luminal epithelium was greatest (P<0.01) with 24 h of E2 exposure compared with 0 h and 6 h. When expressed as the percentage change in uterine cell proliferation, feeding LSM for 14 d negated these effects. Only length of E2 exposure impacted vascularity with capillary number density at 6 h of E2 exposure being greater (P=0.02) than at 24 h. While mRNA expression of several angiogenic factors was influenced by E2, there was a LSM×E2 interaction (P≤0.03) only on vascular endothelial growth factor receptor 2 and fibroblast growth factor receptor 2C. It appears that growth and angiogenesis of E2 sensitive tissues may be influenced by the duration of LSM feeding.

  • estradiol 17β and Linseed Meal interact to alter visceral organ mass and hormone concentrations from ovariectomized ewes
    Domestic Animal Endocrinology, 2009
    Co-Authors: M R Oneil, G P Lardy, L P Reynolds, M E Wilso, C O Lemley, J S Cato, K A Vonnahme
    Abstract:

    Abstract To evaluate the estrogenic potential of secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on visceral organ mass, IGF-I, and thyroid hormone (T 3 and T 4 ) concentrations, 48 multiparous, ovariectomized ewes (54.6±1.1kg) were used in a 3×4 factorial arrangement. Main effects were length of LSM feeding (0, 1, 7, or 14 d) and length of exposure to estradiol-17β (E 2 ) implant (0, 6, or 24h prior to tissue collection). Implanting ewes with E 2 for 24h increased liver mass relative to empty body weight (EBW; g/kg EBW) compared with ewes implanted for 0 or 6h ( P ≤0.03), whereas feeding LSM for 14 d decreased liver mass compared with ewes fed LSM for 1 or 7 d ( P ≤0.02). There was an LSM×E 2 interaction ( P =0.01) for duodenal mass (g/kg EBW), LSM, and E 2 tended ( P =0.07) to influence the stomach complex mass; however, ileal mass was not affected. Neither LSM nor E 2 affected ( P ≥0.12) CYP2C or CYP3A mRNA expression or cellularity of the liver. Exogenous E 2 influenced circulating concentrations of IGF-I, T 3 , and T 4 . The estrogenic or anti-estrogenic potential of LSM is dependent upon the tissue, exposure to E 2 , and the duration of LSM feeding. Feeding LSM during gestation, lactation, or during the grow-finish phase warrants further investigation.

  • impacts of Linseed Meal and estradiol 17β on mass cellularity angiogenic factors and vascularity of the jejunum
    Journal of Animal Science, 2008
    Co-Authors: M R Oneil, G P Lardy, L P Reynolds, J S Cato, K A Vonnahme
    Abstract:

    To evaluate the estrogenic potential of the phytoestrogen secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on jejunal mass, cellular proliferation, vascularity, and expression of angiogenic factors and their receptors, 48 ovariectomized ewes (54.6 +/- 1.1 kg) were fed a diet containing 12.5% LSM for 0, 1, 7, or 14 d and implanted with estradiol-17beta (E(2)) for 0, 6, or 24 h before tissue collection. Angiogenic factors and receptors measured included vascular endothelial growth factor (VEGF), VEGF receptor-1 (FLT), VEGF receptor-2 (KDR), fibroblast growth factor (FGF), FGF receptor 2 IIIc (FGFR), angiopoietin (ANG)-1, ANG-2, ANG receptor (Tie-2), endothelial nitric oxide synthase (eNOS), and soluble guanylate cyclase (sGC). There was a LSM x E(2) interaction (P = 0.003) on the jejunal cellular proliferation index. Jejunal cellular proliferation increased (P 0.75) or vascular surface area (P > 0.29) of the jejunal villi. Expression of mRNA for the angiogenic factors VEGF, FGF, FGFR, ANG-1, ANG-2, and Tie-2 were not altered (P > 0.33) by feeding LSM or implanting ewes with E(2). Implanting ewes with E(2) for 6 h increased (P = 0.04) eNOS expression compared with ewes implanted for 0 h. Feeding LSM and implanting ewes with E(2) interacted to alter mRNA expression of FLT (P = 0.04), KDR (P 0.11). The impacts of E(2) and LSM on nutrient uptake and growth during physiologically important time points are unknown.

K A Vonnahme - One of the best experts on this subject based on the ideXlab platform.

  • short communication growth and attainment of puberty in calves from cows supplemented with Linseed Meal during late gestation and early lactation
    Canadian Journal of Animal Science, 2012
    Co-Authors: R Ilse, G P Lardy, V L Anderso, D S Uchana, K G Odde, K A Vonnahme
    Abstract:

    Ilse, B. R., Anderson, V. L., Buchanan, D. S., Odde, K. G., Lardy, G. P. and Vonnahme, K. A. 2012. Short Communication: Growth and attainment of puberty in calves from cows supplemented with Linseed Meal during late gestation and early lactation. Can. J. Anim. Sci. 92: 443–447. To test the objective that a Linseed Meal (LSM) supplement in beef cows during late gestation and early lactation would impact offspring growth performance, steer carcass composition, and attainment of puberty in heifer calves, multiparous beef cows received either LSM or a control supplement for the last 60 d of gestation (exp. 1; n=72) or during the first 60 d of lactation (exp. 2; n=91). In both experiments, birth weight, weaning weight, and ADG of calves were not affected (P>0.31) by LSM supplementation. There was no effect (P>0.09) of supplementation on carcass characteristics of steer progeny fed to market weight. In exps. 1 and 2, attainment of puberty in heifer calves was not influenced (P>0.58) by supplement type. Linseed ...

  • impacts of Linseed Meal and estradiol 17β on cellularity angiogenic and vasoactive factor mrna expression and vascularity of the uterus in ovariectomized ewes
    Canadian Journal of Animal Science, 2012
    Co-Authors: R Ilse, G P Lardy, M R Oneil, L P Reynolds, K A Vonnahme
    Abstract:

    Ilse, B. R., O'Neil, M. R., Lardy, G. P., Reynolds, L. P. and Vonnahme, K. A. 2012. Impacts of Linseed Meal and estradiol-17β on cellularity, angiogenic and vasoactive factor mRNA expression, and vascularity of the uterus in ovariectomized ewes. Can. J. Anim. Sci. 92: 297–306. The objective of the current study was to determine the estrogenic potential of the phytoestrogen secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on uterine cell proliferation, vascularity, and angiogenic factor mRNA expression. Ovariectomized ewes (n=48) were fed a diet containing 12.5% LSM for 0, 1, 7, or 14 d and implanted with estradiol-17β (E2) for 0, 6, or 24 h before tissue collection. There was an interaction of LSM×E2 on uterine mass (grams; P=0.03; percentage change; P<0.003). Uterine mass increased (P≤0.02) after 24 h of E2 exposure on days 1, 7, and 14 of LSM feeding, with the greatest mass occurring in ewes exposed to E2 for 24 h and 1 d LSM feeding. Regardless of days fed LSM, after 24 h of E2 exposu...

  • impacts of Linseed Meal and estradiol 17β on cellularity angiogenic and vasoactive factor mrna expression and vascularity of the uterus in ovariectomized ewes
    Canadian Journal of Plant Science, 2012
    Co-Authors: R Ilse, G P Lardy, M R Oneil, L P Reynolds, K A Vonnahme
    Abstract:

    Ilse, B. R., O'Neil, M. R., Lardy, G. P., Reynolds, L. P. and Vonnahme, K. A. 2012. Impacts of Linseed Meal and estradiol-17β on cellularity, angiogenic and vasoactive factor mRNA expression, and vascularity of the uterus in ovariectomized ewes. Can. J. Anim. Sci. 92: 297–306. The objective of the current study was to determine the estrogenic potential of the phytoestrogen secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on uterine cell proliferation, vascularity, and angiogenic factor mRNA expression. Ovariectomized ewes (n=48) were fed a diet containing 12.5% LSM for 0, 1, 7, or 14 d and implanted with estradiol-17β (E2) for 0, 6, or 24 h before tissue collection. There was an interaction of LSM×E2 on uterine mass (grams; P=0.03; percentage change; P<0.003). Uterine mass increased (P≤0.02) after 24 h of E2 exposure on days 1, 7, and 14 of LSM feeding, with the greatest mass occurring in ewes exposed to E2 for 24 h and 1 d LSM feeding. Regardless of days fed LSM, after 24 h of E2 exposure uterine mass was greatest. The greatest percentage increase in uterine mass occurred in ewes exposed to E2 for 24 h and fed 1 d of LSM. Cell proliferation within the uterine luminal epithelium was greatest (P<0.01) with 24 h of E2 exposure compared with 0 h and 6 h. When expressed as the percentage change in uterine cell proliferation, feeding LSM for 14 d negated these effects. Only length of E2 exposure impacted vascularity with capillary number density at 6 h of E2 exposure being greater (P=0.02) than at 24 h. While mRNA expression of several angiogenic factors was influenced by E2, there was a LSM×E2 interaction (P≤0.03) only on vascular endothelial growth factor receptor 2 and fibroblast growth factor receptor 2C. It appears that growth and angiogenesis of E2 sensitive tissues may be influenced by the duration of LSM feeding.

  • Linseed Meal during early pregnancy increases litter size in pigs without affecting post natal growth
    Canadian Journal of Animal Science, 2010
    Co-Authors: K A Vonnahme, R C Zimprich, E K Harris, E P Erg, D J Newma, D S Uchana
    Abstract:

    Vonnahme,K.A.,Zimprich,R.C.,Harris,E.K.,Berg,E.P.,Newman,D.J.andBuchanan,D.S.2010.LinseedMealduringearlypregnancyincreaseslittersizeinpigswithoutaffectingpost-natalgrowth.Can.J.Anim.Sci.90:491 493.TodeterminehowfeedingLinseedMeal(LSM)duringgestationinfluenceslittersize,placentalweight,andpigletgrowth,sows(n 30) received a phytoestrogen-free Control diet throughout gestation; 12.5% LSM diet throughout gestation(LSM114);or12.5%LSMdietfromday1today15ofgestationandcontroldietuntilparturition(LSM15).Maternaldietdidnotaffectbirthweight,placentalweight,orpostnatalgrowth.Thenumberoffullyformedpigletswasincreased(P 0.05)inLSM15sowscomparedwithControlandLSM114sows(13.5vs.10.1and11.691.0,respectively).FeedingLSMduringthefirst2wkafterbreedingmayenhancelittersize.Key words: Littersize,LinseedMeal,pigVonnahme,K.A.,Zimprich,R.C.,Harris,E.K.,Berg,E.P.,Newman,D.J.etBuchanan,D.S.2010.Letourteaudelinende´butdegrossesseaugmentelatailledesporte´eschezlesporcssansaffecterlacroissancepost-natale.Can.J.Anim.Sci.90:491 493.Afindede´terminercommentnourritureavecfarinedesgrainesdelin(LSM)pendantlagestationinfluencetaille de litie`re, poid placentaire, et croissance des porcelets, truies (n 30) ont recu un re´gime de controˆle sans-phytoestrogenpendanttoutelagestation;alimentationLSMde12,5%toutesagestation(LSM114);ou12,5%LSMDie`tedejour1a`15dure´gimedegestation,etcontroˆlejusqu’a`laparturition(LSM15).Alimentationmaternellen’affectaitpasnaissance, poids placentaire ou croissance postnatale. Porcelets entie`rement forme´se´te´augmente´es (P 0,05) dans lestruies LSM15 par rapport a`la commande et LSM114 truies (13,5 VS 10.1 et 11,691.0, respectivement). AlimentationLSMpendantlesdeuxpremie`ressemainesapre`sreproductionpeutame´liorerlatailledelalitie`re.Mots cle´s: Tailledelitie`re,farinedesgrainesdelin,porc

  • estradiol 17β and Linseed Meal interact to alter visceral organ mass and hormone concentrations from ovariectomized ewes
    Domestic Animal Endocrinology, 2009
    Co-Authors: M R Oneil, G P Lardy, L P Reynolds, M E Wilso, C O Lemley, J S Cato, K A Vonnahme
    Abstract:

    Abstract To evaluate the estrogenic potential of secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on visceral organ mass, IGF-I, and thyroid hormone (T 3 and T 4 ) concentrations, 48 multiparous, ovariectomized ewes (54.6±1.1kg) were used in a 3×4 factorial arrangement. Main effects were length of LSM feeding (0, 1, 7, or 14 d) and length of exposure to estradiol-17β (E 2 ) implant (0, 6, or 24h prior to tissue collection). Implanting ewes with E 2 for 24h increased liver mass relative to empty body weight (EBW; g/kg EBW) compared with ewes implanted for 0 or 6h ( P ≤0.03), whereas feeding LSM for 14 d decreased liver mass compared with ewes fed LSM for 1 or 7 d ( P ≤0.02). There was an LSM×E 2 interaction ( P =0.01) for duodenal mass (g/kg EBW), LSM, and E 2 tended ( P =0.07) to influence the stomach complex mass; however, ileal mass was not affected. Neither LSM nor E 2 affected ( P ≥0.12) CYP2C or CYP3A mRNA expression or cellularity of the liver. Exogenous E 2 influenced circulating concentrations of IGF-I, T 3 , and T 4 . The estrogenic or anti-estrogenic potential of LSM is dependent upon the tissue, exposure to E 2 , and the duration of LSM feeding. Feeding LSM during gestation, lactation, or during the grow-finish phase warrants further investigation.

M R Oneil - One of the best experts on this subject based on the ideXlab platform.

  • impacts of Linseed Meal and estradiol 17β on cellularity angiogenic and vasoactive factor mrna expression and vascularity of the uterus in ovariectomized ewes
    Canadian Journal of Animal Science, 2012
    Co-Authors: R Ilse, G P Lardy, M R Oneil, L P Reynolds, K A Vonnahme
    Abstract:

    Ilse, B. R., O'Neil, M. R., Lardy, G. P., Reynolds, L. P. and Vonnahme, K. A. 2012. Impacts of Linseed Meal and estradiol-17β on cellularity, angiogenic and vasoactive factor mRNA expression, and vascularity of the uterus in ovariectomized ewes. Can. J. Anim. Sci. 92: 297–306. The objective of the current study was to determine the estrogenic potential of the phytoestrogen secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on uterine cell proliferation, vascularity, and angiogenic factor mRNA expression. Ovariectomized ewes (n=48) were fed a diet containing 12.5% LSM for 0, 1, 7, or 14 d and implanted with estradiol-17β (E2) for 0, 6, or 24 h before tissue collection. There was an interaction of LSM×E2 on uterine mass (grams; P=0.03; percentage change; P<0.003). Uterine mass increased (P≤0.02) after 24 h of E2 exposure on days 1, 7, and 14 of LSM feeding, with the greatest mass occurring in ewes exposed to E2 for 24 h and 1 d LSM feeding. Regardless of days fed LSM, after 24 h of E2 exposu...

  • impacts of Linseed Meal and estradiol 17β on cellularity angiogenic and vasoactive factor mrna expression and vascularity of the uterus in ovariectomized ewes
    Canadian Journal of Plant Science, 2012
    Co-Authors: R Ilse, G P Lardy, M R Oneil, L P Reynolds, K A Vonnahme
    Abstract:

    Ilse, B. R., O'Neil, M. R., Lardy, G. P., Reynolds, L. P. and Vonnahme, K. A. 2012. Impacts of Linseed Meal and estradiol-17β on cellularity, angiogenic and vasoactive factor mRNA expression, and vascularity of the uterus in ovariectomized ewes. Can. J. Anim. Sci. 92: 297–306. The objective of the current study was to determine the estrogenic potential of the phytoestrogen secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on uterine cell proliferation, vascularity, and angiogenic factor mRNA expression. Ovariectomized ewes (n=48) were fed a diet containing 12.5% LSM for 0, 1, 7, or 14 d and implanted with estradiol-17β (E2) for 0, 6, or 24 h before tissue collection. There was an interaction of LSM×E2 on uterine mass (grams; P=0.03; percentage change; P<0.003). Uterine mass increased (P≤0.02) after 24 h of E2 exposure on days 1, 7, and 14 of LSM feeding, with the greatest mass occurring in ewes exposed to E2 for 24 h and 1 d LSM feeding. Regardless of days fed LSM, after 24 h of E2 exposure uterine mass was greatest. The greatest percentage increase in uterine mass occurred in ewes exposed to E2 for 24 h and fed 1 d of LSM. Cell proliferation within the uterine luminal epithelium was greatest (P<0.01) with 24 h of E2 exposure compared with 0 h and 6 h. When expressed as the percentage change in uterine cell proliferation, feeding LSM for 14 d negated these effects. Only length of E2 exposure impacted vascularity with capillary number density at 6 h of E2 exposure being greater (P=0.02) than at 24 h. While mRNA expression of several angiogenic factors was influenced by E2, there was a LSM×E2 interaction (P≤0.03) only on vascular endothelial growth factor receptor 2 and fibroblast growth factor receptor 2C. It appears that growth and angiogenesis of E2 sensitive tissues may be influenced by the duration of LSM feeding.

  • estradiol 17β and Linseed Meal interact to alter visceral organ mass and hormone concentrations from ovariectomized ewes
    Domestic Animal Endocrinology, 2009
    Co-Authors: M R Oneil, G P Lardy, L P Reynolds, M E Wilso, C O Lemley, J S Cato, K A Vonnahme
    Abstract:

    Abstract To evaluate the estrogenic potential of secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on visceral organ mass, IGF-I, and thyroid hormone (T 3 and T 4 ) concentrations, 48 multiparous, ovariectomized ewes (54.6±1.1kg) were used in a 3×4 factorial arrangement. Main effects were length of LSM feeding (0, 1, 7, or 14 d) and length of exposure to estradiol-17β (E 2 ) implant (0, 6, or 24h prior to tissue collection). Implanting ewes with E 2 for 24h increased liver mass relative to empty body weight (EBW; g/kg EBW) compared with ewes implanted for 0 or 6h ( P ≤0.03), whereas feeding LSM for 14 d decreased liver mass compared with ewes fed LSM for 1 or 7 d ( P ≤0.02). There was an LSM×E 2 interaction ( P =0.01) for duodenal mass (g/kg EBW), LSM, and E 2 tended ( P =0.07) to influence the stomach complex mass; however, ileal mass was not affected. Neither LSM nor E 2 affected ( P ≥0.12) CYP2C or CYP3A mRNA expression or cellularity of the liver. Exogenous E 2 influenced circulating concentrations of IGF-I, T 3 , and T 4 . The estrogenic or anti-estrogenic potential of LSM is dependent upon the tissue, exposure to E 2 , and the duration of LSM feeding. Feeding LSM during gestation, lactation, or during the grow-finish phase warrants further investigation.

  • impacts of Linseed Meal and estradiol 17β on mass cellularity angiogenic factors and vascularity of the jejunum
    Journal of Animal Science, 2008
    Co-Authors: M R Oneil, G P Lardy, L P Reynolds, J S Cato, K A Vonnahme
    Abstract:

    To evaluate the estrogenic potential of the phytoestrogen secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on jejunal mass, cellular proliferation, vascularity, and expression of angiogenic factors and their receptors, 48 ovariectomized ewes (54.6 +/- 1.1 kg) were fed a diet containing 12.5% LSM for 0, 1, 7, or 14 d and implanted with estradiol-17beta (E(2)) for 0, 6, or 24 h before tissue collection. Angiogenic factors and receptors measured included vascular endothelial growth factor (VEGF), VEGF receptor-1 (FLT), VEGF receptor-2 (KDR), fibroblast growth factor (FGF), FGF receptor 2 IIIc (FGFR), angiopoietin (ANG)-1, ANG-2, ANG receptor (Tie-2), endothelial nitric oxide synthase (eNOS), and soluble guanylate cyclase (sGC). There was a LSM x E(2) interaction (P = 0.003) on the jejunal cellular proliferation index. Jejunal cellular proliferation increased (P 0.75) or vascular surface area (P > 0.29) of the jejunal villi. Expression of mRNA for the angiogenic factors VEGF, FGF, FGFR, ANG-1, ANG-2, and Tie-2 were not altered (P > 0.33) by feeding LSM or implanting ewes with E(2). Implanting ewes with E(2) for 6 h increased (P = 0.04) eNOS expression compared with ewes implanted for 0 h. Feeding LSM and implanting ewes with E(2) interacted to alter mRNA expression of FLT (P = 0.04), KDR (P 0.11). The impacts of E(2) and LSM on nutrient uptake and growth during physiologically important time points are unknown.

L P Reynolds - One of the best experts on this subject based on the ideXlab platform.

  • impacts of Linseed Meal and estradiol 17β on cellularity angiogenic and vasoactive factor mrna expression and vascularity of the uterus in ovariectomized ewes
    Canadian Journal of Animal Science, 2012
    Co-Authors: R Ilse, G P Lardy, M R Oneil, L P Reynolds, K A Vonnahme
    Abstract:

    Ilse, B. R., O'Neil, M. R., Lardy, G. P., Reynolds, L. P. and Vonnahme, K. A. 2012. Impacts of Linseed Meal and estradiol-17β on cellularity, angiogenic and vasoactive factor mRNA expression, and vascularity of the uterus in ovariectomized ewes. Can. J. Anim. Sci. 92: 297–306. The objective of the current study was to determine the estrogenic potential of the phytoestrogen secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on uterine cell proliferation, vascularity, and angiogenic factor mRNA expression. Ovariectomized ewes (n=48) were fed a diet containing 12.5% LSM for 0, 1, 7, or 14 d and implanted with estradiol-17β (E2) for 0, 6, or 24 h before tissue collection. There was an interaction of LSM×E2 on uterine mass (grams; P=0.03; percentage change; P<0.003). Uterine mass increased (P≤0.02) after 24 h of E2 exposure on days 1, 7, and 14 of LSM feeding, with the greatest mass occurring in ewes exposed to E2 for 24 h and 1 d LSM feeding. Regardless of days fed LSM, after 24 h of E2 exposu...

  • impacts of Linseed Meal and estradiol 17β on cellularity angiogenic and vasoactive factor mrna expression and vascularity of the uterus in ovariectomized ewes
    Canadian Journal of Plant Science, 2012
    Co-Authors: R Ilse, G P Lardy, M R Oneil, L P Reynolds, K A Vonnahme
    Abstract:

    Ilse, B. R., O'Neil, M. R., Lardy, G. P., Reynolds, L. P. and Vonnahme, K. A. 2012. Impacts of Linseed Meal and estradiol-17β on cellularity, angiogenic and vasoactive factor mRNA expression, and vascularity of the uterus in ovariectomized ewes. Can. J. Anim. Sci. 92: 297–306. The objective of the current study was to determine the estrogenic potential of the phytoestrogen secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on uterine cell proliferation, vascularity, and angiogenic factor mRNA expression. Ovariectomized ewes (n=48) were fed a diet containing 12.5% LSM for 0, 1, 7, or 14 d and implanted with estradiol-17β (E2) for 0, 6, or 24 h before tissue collection. There was an interaction of LSM×E2 on uterine mass (grams; P=0.03; percentage change; P<0.003). Uterine mass increased (P≤0.02) after 24 h of E2 exposure on days 1, 7, and 14 of LSM feeding, with the greatest mass occurring in ewes exposed to E2 for 24 h and 1 d LSM feeding. Regardless of days fed LSM, after 24 h of E2 exposure uterine mass was greatest. The greatest percentage increase in uterine mass occurred in ewes exposed to E2 for 24 h and fed 1 d of LSM. Cell proliferation within the uterine luminal epithelium was greatest (P<0.01) with 24 h of E2 exposure compared with 0 h and 6 h. When expressed as the percentage change in uterine cell proliferation, feeding LSM for 14 d negated these effects. Only length of E2 exposure impacted vascularity with capillary number density at 6 h of E2 exposure being greater (P=0.02) than at 24 h. While mRNA expression of several angiogenic factors was influenced by E2, there was a LSM×E2 interaction (P≤0.03) only on vascular endothelial growth factor receptor 2 and fibroblast growth factor receptor 2C. It appears that growth and angiogenesis of E2 sensitive tissues may be influenced by the duration of LSM feeding.

  • estradiol 17β and Linseed Meal interact to alter visceral organ mass and hormone concentrations from ovariectomized ewes
    Domestic Animal Endocrinology, 2009
    Co-Authors: M R Oneil, G P Lardy, L P Reynolds, M E Wilso, C O Lemley, J S Cato, K A Vonnahme
    Abstract:

    Abstract To evaluate the estrogenic potential of secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on visceral organ mass, IGF-I, and thyroid hormone (T 3 and T 4 ) concentrations, 48 multiparous, ovariectomized ewes (54.6±1.1kg) were used in a 3×4 factorial arrangement. Main effects were length of LSM feeding (0, 1, 7, or 14 d) and length of exposure to estradiol-17β (E 2 ) implant (0, 6, or 24h prior to tissue collection). Implanting ewes with E 2 for 24h increased liver mass relative to empty body weight (EBW; g/kg EBW) compared with ewes implanted for 0 or 6h ( P ≤0.03), whereas feeding LSM for 14 d decreased liver mass compared with ewes fed LSM for 1 or 7 d ( P ≤0.02). There was an LSM×E 2 interaction ( P =0.01) for duodenal mass (g/kg EBW), LSM, and E 2 tended ( P =0.07) to influence the stomach complex mass; however, ileal mass was not affected. Neither LSM nor E 2 affected ( P ≥0.12) CYP2C or CYP3A mRNA expression or cellularity of the liver. Exogenous E 2 influenced circulating concentrations of IGF-I, T 3 , and T 4 . The estrogenic or anti-estrogenic potential of LSM is dependent upon the tissue, exposure to E 2 , and the duration of LSM feeding. Feeding LSM during gestation, lactation, or during the grow-finish phase warrants further investigation.

  • impacts of Linseed Meal and estradiol 17β on mass cellularity angiogenic factors and vascularity of the jejunum
    Journal of Animal Science, 2008
    Co-Authors: M R Oneil, G P Lardy, L P Reynolds, J S Cato, K A Vonnahme
    Abstract:

    To evaluate the estrogenic potential of the phytoestrogen secoisolariciresinol diglycoside (SDG) found in Linseed Meal (LSM) on jejunal mass, cellular proliferation, vascularity, and expression of angiogenic factors and their receptors, 48 ovariectomized ewes (54.6 +/- 1.1 kg) were fed a diet containing 12.5% LSM for 0, 1, 7, or 14 d and implanted with estradiol-17beta (E(2)) for 0, 6, or 24 h before tissue collection. Angiogenic factors and receptors measured included vascular endothelial growth factor (VEGF), VEGF receptor-1 (FLT), VEGF receptor-2 (KDR), fibroblast growth factor (FGF), FGF receptor 2 IIIc (FGFR), angiopoietin (ANG)-1, ANG-2, ANG receptor (Tie-2), endothelial nitric oxide synthase (eNOS), and soluble guanylate cyclase (sGC). There was a LSM x E(2) interaction (P = 0.003) on the jejunal cellular proliferation index. Jejunal cellular proliferation increased (P 0.75) or vascular surface area (P > 0.29) of the jejunal villi. Expression of mRNA for the angiogenic factors VEGF, FGF, FGFR, ANG-1, ANG-2, and Tie-2 were not altered (P > 0.33) by feeding LSM or implanting ewes with E(2). Implanting ewes with E(2) for 6 h increased (P = 0.04) eNOS expression compared with ewes implanted for 0 h. Feeding LSM and implanting ewes with E(2) interacted to alter mRNA expression of FLT (P = 0.04), KDR (P 0.11). The impacts of E(2) and LSM on nutrient uptake and growth during physiologically important time points are unknown.

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  • nutritional assessment of Linseed Meal linum usitatissimum l protein concentrate in feed of silver catfish
    Animal Feed Science and Technology, 2020
    Co-Authors: Dirleise Pianesso, Naglezi De Menezes Lovatto, Patricia Ines Mombach, Taida Juliana Adoria, Marina Osmari Dalci, L Loebens, Yuri Bohnenberge Telles, S S Roballo, Leila Picolli Da Silva
    Abstract:

    Abstract Linseed protein concentrate (LPC) was produced in the laboratory and subsequently a feed assay was performed to evaluate the inclusion of increasing levels of LPC in replacement of fish Meal on growth, nutrient utilization, metabolic responses and goblet cells of silver catfish (Rhamdia quelen). Five isotopic and isocaloric diets were formulated, including 0, 100, 200, 300 and 400 g/kg of LPC protein replacing the fish Meal, respectively. Each diet was randomly distributed to quadruplicate groups of 25 fish (initial average weight of 6.13 g) per tank, totaling 20 tanks. The crude protein of LPC was lower (P 0.05) than animals submitted to the 0 g/kg LPC diet. Diets of 300 and 400 g/kg LPC provided higher (P

  • Alternative protein sources in nutrition and metabolism of jundiá:in nature and demucilaged Linseed Meal
    2018
    Co-Authors: Fernanda Rodrigues Goula, Caroline Sefri Speroni, Naglezi De Menezes Lovatto, Uno Biach Loureiro, Ana Betine Ende, Alexandra Pretto, João RadÜnz Neto, Leila Picolli Da Silva
    Abstract:

    This study evaluated the growth response and metabolic effects of partial replacement of animal protein source with in natura (LM) or demucilaged (DLM) Linseed Meal in the diet of jundiá (Rhamdia quelen) juveniles. After demucilagen increased crude protein content and reduced soluble fiber of Linseed Meal. During seven weeks, 240 jundiá juveniles were reared in water recirculation system and fed to apparent satiation with the following diets: control diet (meat and bones Meal and soybean protein concentrate as the main protein sources); 17% LM (17% crude protein of Linseed Meal replacing meat and bones Meal); 17% DLM (17% crude protein of demucilaged Linseed Meal replacing meat and bones Meal) or 35% DLM (35% crude protein of demucilaged Linseed Meal replacing meat and bones Meal). At the end of the experiment, weight, total and standard length of the animals did not differ between treatments, but lower values of feed conversion were found in the control group. As for metabolic response, animals fed with 35% DLM diet showed higher level of glucose and cholesterol in plasma, but triglycerides, albumin, total protein and liver biochemistry (glycogen, glucose, lactate, protein, amino acids, ammonia) were not changed between treatments. The results demonstrated that in natura and demucilaged Linseed Meal can be used in the diet of jundiá without compromising metabolic parameters and final weight.

  • alternative protein sources in nutrition and metabolism of jundia in nature and demucilaged Linseed Meal
    Revista Brasileira de Saúde e Produção Animal, 2015
    Co-Authors: Fernanda Rodrigues Goula, Caroline Sefri Speroni, Naglezi De Menezes Lovatto, Alexandra Pretto, João RadÜnz Neto, Uno Loureiro Ianch, Ana Betine Beutinge Ende, Leila Picolli Da Silva
    Abstract:

    Este estudo avaliou o crescimento e efeitos metabolicos da substituicao parcial da fonte proteica de origem animal pelos farelos de linhaca in natura (FL) e demucilada (FLD) na dieta de juvenis de jundia (Rhamdia quelen). Apos a demucilagem, os niveis de proteina bruta aumentaram e houve reducao da fibra soluvel do farelo de linhaca. Durante sete semanas, 240 juvenis de jundia foram criados em sistema de recirculacao de agua e alimentados ate a saciedade aparente com as seguintes dietas: dieta controle (farinha de carne e ossos e concentrado proteico de soja como as principais fontes proteicas); 17%FL (17% da proteina bruta do farelo de linhaca em substituicao da farinha de carne e ossos); 17% FLD (17% da proteina bruta do farelo de linhaca demucilada em substituicao da farinha de carne e ossos); 35%FLD (35% da proteina bruta do farelo de linhaca demucilada em substituicao da farinha de carne e ossos). Ao final do experimento, peso e comprimento total e padrao nao diferiram entre os tratamentos, porem menores valores de conversao alimentar foram encontrados no grupo controle. Em relacao as repostas metabolicas, os animais alimentados com 35%FLD apresentaram maiores niveis de glicose e colesterol no plasma, porem triglicerideos, albumina, proteinas totais e os parâmetros bioquimicos do figado (glicogenio, glicose, lactato, proteina, aminoacidos, amonia) nao foram alterados entre os tratamentos. Os resultados demonstraram que tanto o farelo de linhaca in natura como o demucilado podem ser utilizados na dieta de jundias sem comprometer os parâmetros metabolicos e de peso final.

  • atividade de enzimas digestivas e parâmetros de crescimento de juvenis de jundia rhamdia quelen alimentados com farelo de linhaca in natura e demucilada activity of digestive enzymes and growth parameters of juvenile jundia rhandia quelen fed Linseed
    2013
    Co-Authors: Fernanda Rodrigues Goula, Caroline Sefri Speroni, Naglezi De Menezes Lovatto, João RadÜnz Neto, Uno Bianch Loureiro, Viviane Correia, Leila Picolli Da Silva
    Abstract:

    This study was conducted out to evaluate the effect of partial replacement of animal protein (PBOA) for crude protein demucilaged Linseed Meal (PBFLD) and in nature (PBFL) in the diet of jundia on growth parameters and digestive enzyme. The treatments were: control diet; 17%FL (Linseed Meal in nature):17% replacement of the PBOA by PBFL; 17%FLD (demucilaged Linseed Meal):17% replacement PBFLD by PBOA and 35%FLD: 35% replacement PBFLD by PBOA. Over seven week, 240 juvenile jundia (14.49 1