The Experts below are selected from a list of 9 Experts worldwide ranked by ideXlab platform

Zhigang Zhou - One of the best experts on this subject based on the ideXlab platform.

  • Orthogonal test design for optimization of Lipid accumulation and Lipid Property in Nannochloropsis oculata for biodiesel production.
    Bioresource technology, 2013
    Co-Authors: Likun Wei, Xuxiong Huang, Zhenzheng Huang, Zhigang Zhou
    Abstract:

    Abstract In order to improve the Property of Nannochloropsis oculata as biodiesel feedstock, a L 9 (3 4 ) orthogonal test on limited nitrogen supplementation (0, 0.22 and 0.44 mmol N L  −1 ), high iron concentration (1.2 × 10 −2 , 1.2 × 10 −1 and 1.2 mmol Fe L −1 ) and culture temperature (10, 20 and 30 °C) was conducted to select the most effective combinational measurement. Results showed that microalgae displayed the highest total Lipid content (60.44 ± 0.68%), the highest neutral Lipid proportion (90.74 ± 0.18%), the highest Lipid yield (152.70 ± 7.40 mg L −1 ) and the largest cetane number (CN, 64.34 ± 0.13) under different combined conditions. There were significant interaction among nitrogen supplementation, iron concentration and culture temperature on the Lipid yield and CN of N. oculata. Nitrogen supplementation, followed by iron concentration and temperature orderly, was the most influential factor in Lipid yield. It is therefore suggested that the combination of 0.44 mmol N L −1 , 1.2 × 10 −1  mmol Fe L −1 and 20 °C was the best measurement for improving the Property of N. oculata as biodiesel feedstock.

Likun Wei - One of the best experts on this subject based on the ideXlab platform.

  • Orthogonal test design for optimization of Lipid accumulation and Lipid Property in Nannochloropsis oculata for biodiesel production.
    Bioresource technology, 2013
    Co-Authors: Likun Wei, Xuxiong Huang, Zhenzheng Huang, Zhigang Zhou
    Abstract:

    Abstract In order to improve the Property of Nannochloropsis oculata as biodiesel feedstock, a L 9 (3 4 ) orthogonal test on limited nitrogen supplementation (0, 0.22 and 0.44 mmol N L  −1 ), high iron concentration (1.2 × 10 −2 , 1.2 × 10 −1 and 1.2 mmol Fe L −1 ) and culture temperature (10, 20 and 30 °C) was conducted to select the most effective combinational measurement. Results showed that microalgae displayed the highest total Lipid content (60.44 ± 0.68%), the highest neutral Lipid proportion (90.74 ± 0.18%), the highest Lipid yield (152.70 ± 7.40 mg L −1 ) and the largest cetane number (CN, 64.34 ± 0.13) under different combined conditions. There were significant interaction among nitrogen supplementation, iron concentration and culture temperature on the Lipid yield and CN of N. oculata. Nitrogen supplementation, followed by iron concentration and temperature orderly, was the most influential factor in Lipid yield. It is therefore suggested that the combination of 0.44 mmol N L −1 , 1.2 × 10 −1  mmol Fe L −1 and 20 °C was the best measurement for improving the Property of N. oculata as biodiesel feedstock.

Xuxiong Huang - One of the best experts on this subject based on the ideXlab platform.

  • Orthogonal test design for optimization of Lipid accumulation and Lipid Property in Nannochloropsis oculata for biodiesel production.
    Bioresource technology, 2013
    Co-Authors: Likun Wei, Xuxiong Huang, Zhenzheng Huang, Zhigang Zhou
    Abstract:

    Abstract In order to improve the Property of Nannochloropsis oculata as biodiesel feedstock, a L 9 (3 4 ) orthogonal test on limited nitrogen supplementation (0, 0.22 and 0.44 mmol N L  −1 ), high iron concentration (1.2 × 10 −2 , 1.2 × 10 −1 and 1.2 mmol Fe L −1 ) and culture temperature (10, 20 and 30 °C) was conducted to select the most effective combinational measurement. Results showed that microalgae displayed the highest total Lipid content (60.44 ± 0.68%), the highest neutral Lipid proportion (90.74 ± 0.18%), the highest Lipid yield (152.70 ± 7.40 mg L −1 ) and the largest cetane number (CN, 64.34 ± 0.13) under different combined conditions. There were significant interaction among nitrogen supplementation, iron concentration and culture temperature on the Lipid yield and CN of N. oculata. Nitrogen supplementation, followed by iron concentration and temperature orderly, was the most influential factor in Lipid yield. It is therefore suggested that the combination of 0.44 mmol N L −1 , 1.2 × 10 −1  mmol Fe L −1 and 20 °C was the best measurement for improving the Property of N. oculata as biodiesel feedstock.

Zhenzheng Huang - One of the best experts on this subject based on the ideXlab platform.

  • Orthogonal test design for optimization of Lipid accumulation and Lipid Property in Nannochloropsis oculata for biodiesel production.
    Bioresource technology, 2013
    Co-Authors: Likun Wei, Xuxiong Huang, Zhenzheng Huang, Zhigang Zhou
    Abstract:

    Abstract In order to improve the Property of Nannochloropsis oculata as biodiesel feedstock, a L 9 (3 4 ) orthogonal test on limited nitrogen supplementation (0, 0.22 and 0.44 mmol N L  −1 ), high iron concentration (1.2 × 10 −2 , 1.2 × 10 −1 and 1.2 mmol Fe L −1 ) and culture temperature (10, 20 and 30 °C) was conducted to select the most effective combinational measurement. Results showed that microalgae displayed the highest total Lipid content (60.44 ± 0.68%), the highest neutral Lipid proportion (90.74 ± 0.18%), the highest Lipid yield (152.70 ± 7.40 mg L −1 ) and the largest cetane number (CN, 64.34 ± 0.13) under different combined conditions. There were significant interaction among nitrogen supplementation, iron concentration and culture temperature on the Lipid yield and CN of N. oculata. Nitrogen supplementation, followed by iron concentration and temperature orderly, was the most influential factor in Lipid yield. It is therefore suggested that the combination of 0.44 mmol N L −1 , 1.2 × 10 −1  mmol Fe L −1 and 20 °C was the best measurement for improving the Property of N. oculata as biodiesel feedstock.

Stefano Giovagnoli - One of the best experts on this subject based on the ideXlab platform.

  • exploring the nano spray drying technology as an innovative manufacturing method for solid Lipid nanoparticle dry powders
    Aaps Pharmscitech, 2019
    Co-Authors: Krystyna Glaubitt, Maurizio Ricci, Stefano Giovagnoli
    Abstract:

    To take advantage of solid-state properties, the nano spray-drying (NSD) technique was investigated as an innovative one-step method to produce solid Lipid nanoparticles (SLN) in the form of a dry powder starting from a Lipid/leucine O/W emulsion. Compritol was chosen as wall-forming Lipid. Rapamycin (Rp) was employed as a model drug to be loaded into SLN. Based on an initial screening, Lutrol F68 was chosen as surfactant and high-shear homogenization as an emulsification method. A two-level fractional factorial design and an extended factorial design were employed to determine critical factors and best preparation conditions. Compritol concentration, l-leucine/Lipid ratio, and Lutrol F68 concentration resulted critical. Best conditions granted 51% yield, 3.2 μm l-leucine/SLN particle size, and a SLN population around 150 nm. All samples showed the presence of Lipid aggregates. Material loss in the emulsification step was found responsible for SLN aggregation and low yield. The almost quantitative Rp loading increased SLN population span. Replacing compritol with cetyl palmitate produced aggregation of dry powders and SLN. Overall, NSD was found a fast method to produce SLN dry powders. More insightful assessment of the emulsification step and Lipid Property effects will be critical to the optimization of the NSD process. Hypotheses account for direct coupling of high-pressure homogenization with NSD for future successful development of this promising manufacturing method.