Lugols Iodine

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Prateek Sharma - One of the best experts on this subject based on the ideXlab platform.

Allan P. Weston - One of the best experts on this subject based on the ideXlab platform.

R Sankareswari - One of the best experts on this subject based on the ideXlab platform.

  • Study of effectiveness of combined test Pap smear, visual inspection with acetic acid and Lugols Iodine for mass screening of premalignant and malignant lesions of cervix -
    International Journal of Reproduction Contraception Obstetrics and Gynecology, 2016
    Co-Authors: V S Nivedhitha, R Sankareswari
    Abstract:

    Background: Cancer cervix is the leading cause of morbidity and mortality in developing nations. This study aims to evaluate the usefulness of visual inspection with acetic acid (VIA) and Lugols Iodine (VILI) as adjunct to improve the sensitivity of cervical cytology with Pap smear and to enhance the test performance. Methods: Study was conducted in Gynaec OPD clinic in SVMCH & RC, Ariyur, Pondicherry during the period of January 2015 to June 2015. 350 patients enrolled in the study, 10 patients (2.8%) had positive Pap smear, 96 patients (27.4%) had inflammatory smears and 244 (69.7%) had normal smear. VIA was positive in 29 patients (8.2%). VILI was positive in 50 patients (14.2%). Results: Sensitivity of Pap smear = 40% (CI 19.82-64.25%), sensitivity of VIA=40% (CI 19.82-64.25%), sensitivity of VILI = 86.66% (CI 62.12-92.26%), sensitivity of VIA+VILI tests = 86.66% (CI 62.12-96.26), sensitivity of combination tests (Pap + VIA + VILI) = 100% (CI 79.60-100.00). As shown by our study, VILI picked up the maximum premalignant lesions confirmed by cervical biopsy (15 premalignant lesions on cervical biopsy, and VILI is positive in 13 cases) and 6 were picked up by VIA, whereas Pap was positive in 6 patients. Conclusions: This study concludes that the effectiveness of cervical cancer screening can be improved by a combination test of Pap, VILI and VIA, even in tertiary centers in India.

Madhya Pradesh - One of the best experts on this subject based on the ideXlab platform.

  • a prospective study for evaluating visual inspection after acetic acid via and Lugols Iodine vili application in screening of premalignant lesions of cervix
    Journal of Evolution of medical and Dental Sciences, 2013
    Co-Authors: Kalpana Yadav, Monika Patidar, Meena Bhargava, Madhya Pradesh
    Abstract:

    AIMS AND OBJECTIVES: To evaluate the potential of VIA & VILI in the screening of preinvasive and invasive lesions in unhealthy cervix and comparing them with colposcopy guided biopsy thereby determining its usefulness in screening. Also to evaluate the correlation of demographic data like age, socioeconomic status, education, residential area, parity, age at marriage, use of various contraceptive methods in premalignant lesions of cervix. METHODS STUDY was conducted on 200 symptomatic and asymptomatic women with abnormal cervices who attended outdoor department of SSMC associated hospital SGMH. All cases were subjected to Pap smear, VIA, VILI and colposcopy, women with premalignant lesion were subjected to directed biopsy from suspicious areas and sent for histopathological examination (HPE). Results of Pap smear, VIA, VILI and colposcopy are compared to HPE report. OBSERVATIONS: On cytology 27.5% of cases had LSIL & HSIL. All were positive by VIA & VILI, of which 80% had dysplasia on biopsy. On colposcopy, incidence of CIN was 38.5%. all were positive on VIA & VILI, out of which, 76.6% were proved dysplastic on colposcopy guided biopsy. VIA when compared with HPR had sensitivity & specificity of 80% & 67% respectively, while that of VILI was found to be 80% & 87% respectively. CONCLUSION: VIA & VILI are simple, inexpensive, low technology test. Both when combined has high sensitivity as well as specificity. This can be practiced by clinicians and paramedics on wide scale. Another advantage is immediate availability of results, so that treatment can be started during same visit.

V S Nivedhitha - One of the best experts on this subject based on the ideXlab platform.

  • Study of effectiveness of combined test Pap smear, visual inspection with acetic acid and Lugols Iodine for mass screening of premalignant and malignant lesions of cervix -
    International Journal of Reproduction Contraception Obstetrics and Gynecology, 2016
    Co-Authors: V S Nivedhitha, R Sankareswari
    Abstract:

    Background: Cancer cervix is the leading cause of morbidity and mortality in developing nations. This study aims to evaluate the usefulness of visual inspection with acetic acid (VIA) and Lugols Iodine (VILI) as adjunct to improve the sensitivity of cervical cytology with Pap smear and to enhance the test performance. Methods: Study was conducted in Gynaec OPD clinic in SVMCH & RC, Ariyur, Pondicherry during the period of January 2015 to June 2015. 350 patients enrolled in the study, 10 patients (2.8%) had positive Pap smear, 96 patients (27.4%) had inflammatory smears and 244 (69.7%) had normal smear. VIA was positive in 29 patients (8.2%). VILI was positive in 50 patients (14.2%). Results: Sensitivity of Pap smear = 40% (CI 19.82-64.25%), sensitivity of VIA=40% (CI 19.82-64.25%), sensitivity of VILI = 86.66% (CI 62.12-92.26%), sensitivity of VIA+VILI tests = 86.66% (CI 62.12-96.26), sensitivity of combination tests (Pap + VIA + VILI) = 100% (CI 79.60-100.00). As shown by our study, VILI picked up the maximum premalignant lesions confirmed by cervical biopsy (15 premalignant lesions on cervical biopsy, and VILI is positive in 13 cases) and 6 were picked up by VIA, whereas Pap was positive in 6 patients. Conclusions: This study concludes that the effectiveness of cervical cancer screening can be improved by a combination test of Pap, VILI and VIA, even in tertiary centers in India.